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Impacts of high temperature,relative air humidity,and vapor pressure deficit on the seed set of contrasting maize genotypes during flowering

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Journal of Integrative Agriculture 2024年第9期23卷 2955-2969页

作者： Xin Dong Baole Li Zhenzhen Yan Ling Guan Shoubing huang Shujun Li Zhiyun Qi Ling tang Honglin Tian Zhongjun Fu hua Yang Chongqing Academy of Agricultural Sciences Chongqing 401329China College of Agronomy and Biotechnology China Agricultural UniversityBeijing 100193China

Heat stress is a major constraint to current and future maize production at the global *** and female reproductive organs both play major roles in increasing seed set under heat stress at flowering,but their relative contributions to seed set are *** this study,a 2-year field experiment including three sowing dates in each year and 20 inbred lines was *** set,kernel number per ear,and grain yield were all reduced by more than 80%in the third sowing dates compared to the first sowing *** viability,silk emergence ratio,and anthesis-silking interval were the key determinants of seed set under heat stress;and their correlation coefficients were 0.89^(***),0.65^(***),and-0.72^(***),*** pressure deficit(VPD)and relative air humidity(RH)both had significant correlations with pollen viability and the silk emergence *** RH can alleviate the impacts of heat on maize seed set by maintaining high pollen viability and a high silk emergence *** a warming climate from 2020 to 2050,VPD will decrease due to the increased *** on their pollen viability and silk emergence ratios,the 20 genotypes fell into four different *** group with high pollen viability and a high silk emergence ratio performed better under heat stress,and their performance can be further improved by combining the improved flowering pattern traits.

关键词： maize pollen viability silk emergence heat stress relative humidity

Bortezomib depended on PRDM1 and TP53 to exert therapeutic effect in activated B-cell-like diffuse large B-cell lymphoma

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Genes & Diseases 2024年第2期11卷 550-553页

作者： Jing tang Yue Li Jiazhu Wu Haorui Shen hua Yin Jinhua Liang Li Wang Jianyong Li Yi Xia Wei Xu Department of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjingJiangsu 210029China Key Laboratory of Hematology of Nanjing Medical University NanjingJiangsu 210029China Collaborative Innovation Center for Cancer Personalized Medicine NanjingJiangsu 210029China

PR/SET domain 1(PRDM1)gene is located on chromosome 6q21,encoding the B lymphocyte-induced maturation protein 1(BLIMP1).1 It is reported that loss of PRDM1 function is exacerbated in activated B-cell-like(ABC)-diffuse large B cell lymphoma(DLBCL)and associated with inferior ***,it remains unclear what leads to PRDM1 inactivation and the drug resistance mechanism caused by abnormal inactivation of *** investigated the contribution of PRDM1 gene as a prognosis and potential therapeutic target for ABC-DLBCL patients and further clarified the possible mechanism of PRDM1 abnormal *** first proposed that TP53 could regulate PRDM1 by histone ubiquitination modification at the post-transcriptional level.

关键词： PRDM1 TP53 therapeutic

国家自然科学基金视角下我国光纤材料与器件领域的分析和展望

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中国科学：信息科学 2024年第4期54卷 976-987页

作者：唐华国家自然科学基金委员会信息科学部北京100085

光纤作为开启信息时代的关键技术之一,自诞生以来引领了信息、物理等众多相关领域的飞速发展.伴随着光纤材料与器件研究的深入和多元化,其应用领域不断扩展,在多个行业中发挥了不可替代的重要作用.本文从国家自然科学基金的视角,结合201... 详细信息

光纤作为开启信息时代的关键技术之一,自诞生以来引领了信息、物理等众多相关领域的飞速发展.伴随着光纤材料与器件研究的深入和多元化,其应用领域不断扩展,在多个行业中发挥了不可替代的重要作用.本文从国家自然科学基金的视角,结合2018-2022年国家自然科学基金中人才项目、重点项目、重大项目、国家重大科研仪器研制项目、面上项目和地区科学基金项目的资助情况,对各立项项目的题目和关键词进行了热词分析,梳理了我国光纤材料与器件领域的研究现状与挑战,在此基础上分析展望了需进一步深入研究和探讨的方向与内容.

关键词：光纤材料与器件国家自然科学基金热词分析前沿热点研究展望

***2 regulates plant height by affecting the main inflorescence length and first effective branch height in Brassica napus L.

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The Crop Journal 2024年第4期12卷 1102-1111页

作者： Chengke Pang Jun Yu Liang Zhang Min tang Hongfang Liu Ying Cai Feng Chen Jiefu Zhang Wei hua Xiaodong Wang Ming Zheng Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences Key Laboratory of Biology and Genetic Improvement of Oil CropsMinistry of Agriculture and Rural AffairsWuhan 430062HubeiChina Key Laboratory of Cotton and Rapeseed Ministry of Agriculture and Rural AffairsKey Laboratory of Jiangsu Province for AgrobiologyInstitute of Industrial CropsJiangsu Academy of Agricultural SciencesNanjing 210014JiangsuChina National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070HubeiChina

Rapeseed(Brassica napus L.)is one of the main oil crops in the world,and increasing its yield is of great significance for ensuring the safety of edible ***,improving rapeseed plant architecture is an effective way to increase rapeseed yield with higher planting ***,the regulatory mechanism of rapeseed plant architecture is poorly *** this study,a dwarf rapeseed mutant dwarf08(df08)is obtained by ethyl methane sulfonate(EMS)-*** decrease in plant height of df08 is mainly caused by the reduction in main inflorescence length and first effective branch height and controlled by a single semi-dominant *** hybrid plants(F1)show a semi-dwarf *** map-based cloning and transgenic assay,we confirm that the nonsynonymous single nucleotide variant(SNV)(C to T)in ***2,which is homologous with Arabidopsis(Arabidopsis thaliana)BIN2,is responsible for the dwarfism of ***2 interacts with BnaBZR1/BES1 and involves in brassinosteroids(BRs)signal *** to Leucine substitution in 284(P284L)enhances the protein stability of ***2-D,disrupts BRs signal transduction and affects the expression of genes regulating cell division,leading to dwarfism of *** study provides a new insight for the mechanism of rapeseed plant height regulation and creates an elite germplasm that can be used for genetic improvement of rapeseed architecture.

关键词： Brassica napus Plant height Brassinosteroids BIN2

Semisynthesis of homogeneous spike RBD glycoforms from SARS-CoV-2 for profiling the correlations between glycan composition and function

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National Science Review 2024年第2期11卷 145-154页

作者： Farong Ye Cheng Li Feng-Liang Liu Xinliang Liu Peng Xu Rong-hua Luo Wenping Song Yong-tang Zheng Tianlei Ying Biao Yu Ping Wang Center for Chemical Glycobiology Frontiers Science Center for Transformative Molecules Zhangjiang Institute for Advanced Study School of Chemistry and Chemical Engineering Shanghai Jiao Tong University MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection Shanghai Institute of Infectious Disease and BiosecurityShanghai Engineering Research Center for Synthetic ImmunologySchool of Basic Medical Sciences Shanghai Medical College Fudan University Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province Center for Biosafety Mega-Science Kunming Institute of ZoologyChinese Academy of Sciences State Key Laboratory of Bioorganic and Natural Products Chemistry Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shenzhen Research Institute of Shanghai Jiao Tong University

Vaccines have been the primary remedy in the global fight against coronavirus disease 2019（COVID-19）.The receptor-binding domain（RBD） of the spike protein, a critical viral immunogen, is affected by the heterogeneity of its glycan structures and relatively low immunogenicity. Here, we describe a scalable synthetic platform that enables the precise synthesis of homogeneously glycosylated RBD, facilitating the elucidation of carbohydrate structure–function relationships. Five homogeneously glycosylated RBDs bearing biantennary glycans were prepared, three of which were conjugated to T-helper epitope(Tpep) from tetanus toxoid to improve their weak immune response. Relative to natural HEK293-derived RBD, synthetic RBDs with biantennary N-glycan elicited a higher level of neutralising antibodies against SARS-CoV-2 in mice. Furthermore, RBDs containing Tpepelicited significant immune responses in transgenic mice expressing human angiotensin-converting enzyme 2. Our collective data suggest that trimming the N-glycans and Tpepconjugation of RBD could potentially serve as an effective strategy for developing subunit vaccines providing efficient protection.

关键词： peptide ligation glycosylation glycoprotein

Assessing the current situation and the influencing factors affecting perceived stigma among older patients after leukemia diagnosis

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World Journal of Psychiatry 2024年第6期14卷 812-821页

作者： Xuan tang Shuang-Qin Chen Jiang-hua huang Cai-Feng Deng Jie-Qiong Zou Juan Zuo Department of Neurology Hengyang Medical SchoolUniversity of South ChinaHengyang 421001Hunan ProvinceChina Department of Hematology Hengyang Medical SchoolUniversity of South ChinaHengyang 421001Hunan ProvinceChina

BACKGROUND Psychological problems are becoming increasingly prominent among older patients with leukemia,with patients potentially facing stigmatization after ***,there is limited research on the stigma experienced by these patients and the factors that may contribute to *** To investigate the stigma faced by older patients after being diagnosed with leukemia and to analyze the potential influencing *** A retrospective analysis was conducted using clinical data obtained from questionnaire surveys,interviews,and the medical records of older patients with leukemia admitted to the Hengyang Medical School from June 2020 to June *** data obtained included participants’basic demographic information,medical history,leukemia type,family history of leukemia,average monthly family income,pension,and tendency to conceal *** Chinese versions of the Social Impact Scale(SIS),Perceived Social Support Scale(PSSS),Self-Rating Anxiety Scale(SAS),and Self-Rating Depression Scale(SDS)were used to assess indicators related to stigma,social support,and mental health *** used Pearson’s correlation coefficient to analyze the strength and direction of the relationship between the scores of each scale,and regression analysis to explore the factors related to the stigma of older patients with leukemia after *** Data from 120 patients with leukemia aged 65-80 years were *** total score on the SIS and PSSS was 43.60±4.07 and 37.06±2.87,*** SAS score was 58.35±8.32 and the SDS score was 60.58±*** stigma experienced by older leukemia patients was negatively correlated with social support(r=-0.691,P<0.05)and positively correlated with anxiety and depression(r=0.506,0.382,P<0.05).Age,education level,smoking status,average monthly family income,pension,and tendency to conceal illness were significantly associated with the participants’level of stigma(P<0.05).Age,smoking status,social support,anxiety,and depressi

关键词： Senile leukemia Stigma Social support Anxiety Depression Influencing factors

Research progress on temperature field evolution of hot reservoirs under low-temperature tailwater reinjection

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Journal of Groundwater Science and Engineering 2024年第2期12卷 205-222页

作者： Xin Wang Guo-qiang Zhou Yan-guang Liu Ying-nan Zhang Mei-hua Wei Kai Bian School of Earth science and Engineering Hebei University of EngineeringHandan 056038HebeiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuang 050061China Technology Innovation Center of Geothermal&Hot Dry Rock Exploration and Development Ministry of Natural ResourcesShijiazhuang 050061China Shanxi Key Laboratory for Exploration and Exploitation of Geothermal Resources Taiyuan 030024China Shanxi Geological Engineering Exploration Institute Taiyuan 030024China

This paper focuses on the study of the evolutionary mechanism governing the temperature field of geothermal reservoir under low-temperature tailwater reinjection conditions,which is crucial for the sustainable geothermal energy *** advancing exploitation of geothermal resources deepens,precise understanding of this mechanism becomes paramount for devising effective reinjection strategies,optimizing reservoir utilization,and bolstering the economic viability of geothermal energy *** article presents a comprehensive review of temperature field evolution across diverse heterogeneous thermal reservoirs under low-temperature tailwater reinjection conditions,and analyzes key factors influ-encing this *** evaluates existing research methods,highlighting their strengths and *** study identifies gaps in the application of rock seepage and heat transfer theories on a large scale,alongside the need for enhanced accuracy in field test results,particularly regarding computational effi-ciency of fractured thermal reservoir models under multi-well reinjection *** address these shortcomings,the study proposes conducting large-scale rock seepage and heat transfer experiments,coupled with multi-tracer techniques for field testing,aimed at optimizing fractured thermal reservoir models'computational efficiency under multi-well reinjection ***,it suggests integrat-ing deep learning methods into research *** initiatives are of significance in deepening the understanding of the evolution process of the temperature field in deep thermal reservoirs and enhancing the sustainability of deep geothermal resource development.

关键词： Geothermal reinjection Seepage heat transfer Tracer test Numerical simulation Thermal breakthrough

Layered niobium carbide enabling excellent kinetics and cycling stability of Li-Mg-B-H hydrogen storage material Layered niobium carbide enabling excellent kinetics

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Rare Metals 2024年第3期43卷 1153-1166页

作者： Li-Wen Lu Hui Luo guang-Xu Li Yun Li Xin-hua Wang Cun-Ke huang Zhi-QiangLan Wen-Zheng Zhou Jin Guo Mohammad Ismail Hai-Zhen Liu guangxi Novel Battery Materials Research Center of Engineering Technology Guangxi Colleges and Universities Key Laboratory of Blue Energy and Systems IntegrationSchool of Physical Science and TechnologyGuangxi UniversityNanning530004China State Key Laboratory of Featured Metal Materials and Life-Cycle Safety for Composite Structures Nanning530004China School of Mechanical and Electrical Engineering Quzhou College of TechnologyQuzhou324000China Department of Materials Science and Engineering Zhejiang UniversityHangzhou310027China Faculty of Ocean Engineering Technology and Informatics Universiti Malaysia Terengganu21030Kuala NerusTerengganuMalaysia Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjin300071China

The Li-Mg-B-H composite(2LiBH_(4)+MgH_(2))has a high capacity of 11.4 wt%as a hydrogen storage ***,the slow kinetics and poor cycling stability severely restrict its practical *** this work,a layered Nb_(2)C MXene was first synthesized and then introduced to tailor the kinetics and cycling stability of the Li-Mg-B-H *** milled 2LiH+MgB_(2)composites were initially hydrogenated to obtain the 2LiBH_(4)+MgH_(2)*** 2LiBH_(4)+MgH_(2)+5wt%Nb_(2)C can release 9.0 wt%H_(2)in 30 min at 400℃,while it is only 2.7 wt%for the undoped 2LiBH_(4)+MgH_(2).The dehydrogenation activation energies of MgH_(2)and LiBH_(4)are 123 and 154 kJ·mol^(-1)respectively for the 5 wt%Nb_(2)C-doped composite,lower than the undoped composite(164 and 165 kJ·mol^(-1)).The 2LiBH_(4)+MgH_(2)+5 wt%Nb_(2)C possesses excellent cycling stability,with the reversible capacity only slightly reduced from 9.4 wt%for the 1st cycle to 9.3 wt%for the 20th ***_(2)C keeps stable in the composite and acts as an efficient catalyst for the Li-Mg-B-H *** is believed that both the layered structure and the active Nb element contribu te to the enhanced hydrogen storage performances of the Li-Mg-B-H *** work confirms that the Nb_(2)C MXene with layered stru cture has a significant enhancing impact on the Li-Mg-B-H hydrogen storage materials,which is different from the bulk NbC.

关键词： Hydrogen storage Lithium borohydride Magnesium hydride Nb_(2)C MXene

Development status and prospect of underground thermal energy storage technology

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Journal of Groundwater Science and Engineering 2024年第1期12卷 92-108页

作者： Ying-nan Zhang Yan-guang Liu Kai Bian Guo-qiang Zhou Xin Wang Mei-hua Wei School of Earth science and Engineering Hebei University of EngineeringHandan 056038Hebei ProvinceChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuang 050061China Technology Innovation Center of Geothermal&Hot Dry Rock Exploration and Development Ministry of Natural ResourcesShijiazhuang 050061China Shanxi Key Laboratory for Exploration and Exploitation of Geothermal Resources Taiyuan 030024China Shanxi Geological Engineering Exploration Institute Taiyuan 030024China

Underground Thermal Energy Storage(UTES)store unstable and non-continuous energy underground,releasing stable heat energy on *** effectively improve energy utilization and optimize energy *** UTES technology advances,accommodating greater depth,higher temperature and multi-energy complementarity,new research challenges *** paper comprehensively provides a systematic summary of the current research status of *** categorized different types of UTES systems,analyzes the applicability of key technologies of UTES,and evaluate their economic and environmental ***,this paper identifies existing issues with UTES,such as injection blockage,wellbore scaling and corrosion,seepage and heat transfer in cracks,*** suggests deepening the research on blockage formation mechanism and plugging prevention technology,improving the study of anticorrosive materials and water treatment technology,and enhancing the investigation of reservoir fracture network characterization technology and seepage heat *** recommendations serve as valuable references for promoting the high-quality development of UTES.

关键词： Aquifer thermal energy storage Borehole thermal energy storage Cavern thermal energy storage Thermal energy storage technology Benefit evaluation