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Large-Scale Multi-Objective Optimization Algorithm Based on Weighted Overlapping Grouping of Decision Variables

Computer Modeling in Engineering & Sciences 2024年第7期140卷 363-383页

作者： Liang Chen Jingbo zhang Linjie Wu Xingjuan cai Yubin Xu Shanxi Key Laboratory of Big Data Analysis and Parallel Computing Taiyuan University of Science and TechnologyTaiyuan030024China School of State Key Laboratory of Novel Software Technology Nanjing UniversityNanjing210008China

The large-scale multi-objective optimization algorithm(LSMOA),based on the grouping of decision variables,is an advanced method for handling high-dimensional decision ***,in practical problems,the interaction among decision variables is intricate,leading to large group sizes and suboptimal optimization effects;hence a large-scale multi-objective optimization algorithm based on weighted overlapping grouping of decision variables(MOEAWOD)is proposed in this ***,the decision variables are perturbed and categorized into convergence and diversity variables;subsequently,the convergence variables are subdivided into groups based on the interactions among different decision *** the size of a group surpasses the set threshold,that group undergoes a process of weighting and overlapping ***,the interaction strength is evaluated based on the interaction frequency and number of objectives among various decision *** decision variable with the highest interaction in the group is identified and disregarded,and the remaining variables are then reclassified into ***,the decision variable with the strongest interaction is added to each *** minimizes the interactivity between different groups and maximizes the interactivity of decision variables within groups,which contributed to the optimized direction of convergence and diversity exploration with different *** was subjected to testing on 18 benchmark large-scale optimization problems,and the experimental results demonstrate the effectiveness of our *** with the other algorithms,our method is still at an advantage.

关键词： Decision variable grouping large-scale multi-objective optimization algorithms weighted overlapping grouping direction-guided evolution

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Efficient and stable PtFe alloy catalyst for electrocatalytic methanol oxidation with high resistance to CO

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Journal of Energy Chemistry 2024年第3期90卷 327-336,I0008页

作者： Qian Yang Sifan zhang Fengshun Wu Lihua Zhu guang Li Mingzhi Chen An Pei Yingliang Feng Jiangxi Provincial Key Laboratory of Functional Molecular Materials Chemistry College of Chemistry and Chemical EngineeringFaculty of Materials Metallurgy and ChemistryJiangxi University of Science and TechnologyGanzhou 341000JiangxiChina College of Chemistry and Chemical Engineering Xiamen UniversityXiamen 361005FujianChina

Direct methanol fuel cells(DMFC) are widely considered to be an ideal green energy conversion device but their widespread applications are limited by the high price of the Pt-based catalysts and the instability in terms of surface CO toxicity in long-term ***,the PtFe alloy nanoparticles(NPs) with small particle size(~4.12 nm) supported on carbon black catalysts with different Pt/Fe atomic ratios(Pt_(1)Fe_(2)/C,Pt_(3)Fe_(4)/C,Pt_(1)Fe_(1)/C,and Pt_(2)Fe_(1)/C) are successfully prepared for enhanced anti-CO poisoning during methanol oxidation reaction(MOR).The optimal atomic ratio of Pt/Fe for the MOR is 1:2,and the mass activity of Pt_(1)Fe_(2)/C(5.40 A mg_(Pt)^(-1)) is 13.5 times higher than that of conventional commercial Pt/C(Pt/C-JM)(0.40 A mg_(Pt)^(-1)).The introduction of Fe into the Pt lattice forms the PtFe alloy phase,and the electron density of Pt is reduced after forming the PtFe ***-situ Fourier transform infrared results indicate that the addition of oxyphilic metal Fe has reduced the adsorption of reactant molecules on Pt during the *** doping of Fe atoms helps to desorb toxic intermediates and regenerate Pt active sites,promoting the cleavage of C-O bonds with good selectivity of CO_(2)(58.1%).Moreover,the Pt_(1)Fe_(2)/C catalyst exhibits higher CO tolerance,methanol electrooxidation activity,and long-term stability than other Pt_(x)Fe_(y)/C catalysts.

关键词： Alloy catalyst PtFe Methanol oxidation In-situ FTIR CO resistance

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The virulence regulator AbsR in avian pathogenic Escherichia coli has pleiotropic effects on bacterial physiology

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Journal of Integrative Agriculture 2024年第2期23卷 649-668页

作者： Dongfang Zhao Haobo zhang Xinyang zhang Fengwei Jiang Yijing Li Wentong cai Ganwu Li State Key Laboratory for Animal Disease Control and Prevention Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150069China College of Veterinary Medicine Northeast Agricultural UniversityHarbin 150038China National Animal Tuberculosis Reference Laboratory Division of Zoonoses SurveillanceChina Animal Health and Epidemiology CenterQingdao 266032China Department of Veterinary Diagnostic and Production Animal Medicine College of Veterinary MedicineIowa State UniversityAmesIowa 50011-1134the United States

Avian pathogenic Escherichia coli(APEC)belonging to extraintestinal pathogenic ***(ExPEC)can cause severe infections in extraintestinal tissues in birds and humans,such as the lungs and ***(microcin production regulation,locus A,herein renamed AbsR,a blood survival regulator),a member of the MarR(multiple antibiotic resistance regulator)transcriptional regulator family,governs the expression of capsule biosynthetic genes in human ExPEC and represents a promising druggable target for ***,a deep understanding of the AbsR regulatory mechanism as well as its regulon is *** this study,we present a systems-level analysis of the APEC AbsR regulon using ChIP-Seq(chromatin immunoprecipitation sequencing)and RNA-Seq(RNA sequencing)*** found that AbsR directly regulates 99 genes and indirectly regulates 667 ***,we showed that:1)AbsR contributes to antiphagocytotic effects by macrophages and virulence in a mouse model for systemic infection by directly activating the capsular gene cluster;2)AbsR positively impacts biofilm formation via direct regulation of the T2SS(type II secretion system)but plays a marginal role in virulence;and 3)AbsR directly upregulates the acid tolerance signaling system EvgAS to withstand acid stress but is dispensable in ExPEC ***,our data indicate that the role of AbsR in virulence gene regulation is relatively conserved in ExPEC ***,this study provides a comprehensive analysis of the AbsR regulon and regulatory mechanism,and our data suggest that AbsR likely influences virulence primarily through the control of capsule ***,we found that AbsR severely represses the expression of the type I-F CRISPR(clustered regularly interspaced short palindromic repeats)-Cas(CRISPR associated)systems,which could have implications in CRISPR biology and application.

关键词： avian pathogenic Escherichia coli(APEC) extraintestinal pathogenic Escherichia coli(ExPEC) AbsR RNA-Seq ChIP-Seq gene regulation

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Early Triassic Legoupil Formation in Schmidt Peninsula,Antarctic Peninsula:Provenance and Depositional Settings

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Journal of Earth Science 2024年第2期35卷 317-331页

作者： Chao zhang Ying-Chun Cui Chen-guang Liu Fang-Hua Cui Lu-Yuan Wang Wei-Qiang zhang School of Resources and Environmental Engineering Shandong University of TechnologyZibo255049China MNR Key Laboratory for Polar Science Polar Research Institute of ChinaShanghai201209China Key Laboratory of Marine Sedimentology and Environmental Geology First Institute of OceanographyState Oceanic AdministrationQingdao266061China Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and TechnologyQingdao266061China Key Laboratory of Mineral Resources Evaluation in Northeast Asia Ministry of Land and ResourcesChangchun130061China

Geochemical compositions can be used to determine the tectonic setting of sedimentary basins,while where the link of source to sink is no longer preserved,detrital zircon age patterns can aid in resolving the original basin *** metasedimentary Legoupil Formation,located at Cape Legoupil and the Schmidt Peninsula,could give a hint for the tectonic evolution of Antarctic *** this contribution,we constrain the sedimentary provenance of the Legoupil Formation through geochemistry and detrital zircon U-Pb *** petrography and geochemical features indicate that the provenance of the Legoupil Formation could be felsic *** zircon grains record a steady supply of Permian and Ordovician material into the Legoupil *** youngest concordant zircon ages of 262 Ma suggest that the depositional time of Legoupil Formation is no older than Late *** detrital zircon age spectrum of Legoupil Formation suggests that the Legoupil Formation sediments should be derived from regional sources endemic to western Gondwana prior to its *** with the previous studies,geochemistry and detrital zircons reflect an active continental margin tectonic setting and the detrital zircon spectra of Legoupil Formation are similar to the ones deposited in forearc tectonic setting.

关键词： Schmidt Peninsula Legoupil Formation Trinity Peninsula Group detrital zircons Antarctic Peninsula geochemistry

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Heterogeneous engineering of MnSe@NC@ReS2 core-shell nanowires for advanced sodium-/potassium-ion batteries

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Rare Metals 2024年第8期43卷 3713-3723页

作者： Sheng-Jun Lu Jin-Yi Lin cai-Hong Wang Yu-Fei zhang Yi zhang Hao-Sen Fan College of Materials Science and Metallurgy Engineering Guizhou University School of Energy Science and Engineering Nanjing Tech University School of Chemistry and Chemical Engineering Guangzhou University

Sodium-ion batteries（SIBs） and potassium-ion batteries（PIBs） have been attracting great attentions and widely been exploited due to the abundant sodium/potassium ***,the preparation of high-powered anode materials for SIBs/PIBs plays a decisive role for the commercial applications of SIBs/PIBs in the *** selenides are a class of potential anode materials for SIBs/PIBs because of their small band gap and high electrical *** this work,MnSe and ReS2core-shell nanowires connecting by polydopamine derived carbon nanotube（MnSe@NC@ReS2） have been successfully synthesized from growing ReS2nanosheets array on the surface of MnSe@NC nano wires,which present excellent Na+/K+storage *** applied as SIBs anode,the specific capacity of 300 mAh·g-1was maintwined after 400 cycles at the current density of 1.0 A·***,it could also keep 120 mAh·g-1specific capacity after 900 cycles at 1.0 A·g-1for the anode of *** heterogeneous engineering and one-dimensional-two-dimensional（1D-2D） hybrid strategies could provide an ideal strategy for the synthesis of new hetero-structured anode materials with outstanding battery performance for SIBs and PIBs.

关键词： Heterogeneous engineering Core–shell nanowires MnSe@NC@ReS 2 nanowires Na + batteries K + batteries

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Contact Stress Reliability Analysis Model for Cylindrical Gear with Circular Arc Tooth Trace Based on an Improved Metamodel

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Computer Modeling in Engineering & Sciences 2024年第7期140卷 593-619页

作者： Qi zhang Zhixin Chen Yang Wu Guoqi Xiang guang Wen Xuegang zhang Yongchun Xie guangchun Yang School of Intelligent Manufacturing&Automobile Chengdu Industrial Vocational Technical CollegeChengdu610218China School of Intelligent Manufacturing Panzhihua UniversityPanzhihua617000China School of Electrical Engineering Chengdu Industry and Trade CollegeChengdu601165China School of Mechanical Engineering Sichuan UniversityChengdu601165China Chengdu Technological University Chengdu611730China

Although there is currently no unified standard theoretical formula for calculating the contact stress of cylindrical gears with a circular arc tooth trace(referred to as CATT gear),a mathematical model for determining the contact stress of CATT gear is essential for studying how parameters affect its contact stress and building the contact stress limit state equation for contact stress reliability *** this study,a mathematical relationship between design parameters and contact stress is formulated using the *** enhance the model’s accuracy,we propose a new hybrid algorithm that merges the genetic algorithm with the Quantum Particle Swarm optimization algorithm,leveraging the strengths of ***,the“parental inheritance+self-learning”optimization model is used to fine-tune the KrigingMetamodel’s *** this,amathematicalmodel for calculating the contact stress of Variable Hyperbolic Circular-Arc-Tooth-Trace(VH-CATT)gears using the optimized Kriging model was *** then examined how different gear parameters affect the VH-CATT gears’contact *** simulation results show:(1)Improvements in R2,RMSE,and RMAE.R2 rose from0.9852 to 0.9974(a 1.22%increase),nearing 1,suggesting the optimized Kriging Metamodel’s global error is ***,RMSE dropped from3.9210 to 1.6492,a decline of 57.94%.The global error of the GA-IQPSO-Kriging algorithm was also reduced,with RMAE decreasing by 58.69%from 0.1823 to 0.0753,showing the algorithm’s enhanced *** a comparison of ten experimental groups selected randomly,the GA-IQPSO-Kriging and FEM-based contact analysis methods were used to measure contact *** revealed a maximum error of 12.11667 MPA,which represents 2.85%of the real value.(2)Several factors,including the pressure angle,tooth width,modulus,and tooth line radius,are inversely related to contact *** descending order of their impact on the contact stress is:tooth line radius>modulus

关键词： CATT gear contact stress finite element method metamodel hybrid algorithm influencing factors

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Therapeutic potential of targeting protein tyrosine phosphatases in liver diseases

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3295-3311页

作者： Ao Wang Yi zhang Xinting Lv guang Liang Department of Pharmacy and Institute of Inflammation Zhejiang Provincial Affiliated People’s HospitalHangzhou Medical CollegeHangzhou 310014China Key Laboratory of Natural Medicines of the Changbai Mountain Ministry of EducationYanbian UniversityYanji 133002China Chemical Biology Research Center School of Pharmaceutical SciencesWenzhou Medical UniversityWenzhou 325035China

Protein tyrosine phosphorylation is a post-translational modification that regulates protein structure to modulate demic organisms’homeostasis and *** physiological process is regulated by two enzyme families,protein tyrosine kinases(PTKs)and protein tyrosine phosphatases(PTPs).As an important regulator of protein function,PTPs are indispensable for maintaining cell intrinsic physiology in different systems,as well as liver physiological and pathological *** of PTPs has been implicated in multiple liver-related diseases,including chronic liver diseases(CLDs),hepatocellular carcinoma(HCC),and liver injury,and several PTPs are being studied as drug therapeutic ***,given the regulatory role of PTPs in diverse liver diseases,a collated review of their function and mechanism is ***,based on the current research status of targeted therapy,we emphasize the inclusion of several PTP members that are clinically significant in the development and progression of liver *** an emerging breakthrough direction in the treatment of liver diseases,this review summarizes the research status of PTP-targeting compounds in liver diseases to illustrate their potential in clinical ***,this review aims to support the development of novel PTP-based treatment pathways for liver diseases.

关键词： Tyrosine phosphorylation PTPs Signal transduction CLDs HCC Allosteric inhibitor PROTACs Drug development

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Appropriate supply of irrigation and nitrogen produced higher yields of cherry tomatoes

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International Journal of Agricultural and Biological Engineering 2024年第2期17卷 149-158页

作者： Zelin cai Mengchi zhang Jiarui Xie Tingting Kong Yuxuan zhang Zhihao He Zhi zhang College of Horticulture Northwest A&F UniversityYangling 712100ShaanxiChina Key Laboratory of Protected Horticultural Engineering in Northwest Ministry of Agriculture/Shaanxi Province Facility Agriculture Engineering CenterYangling 712100ShaanxiChina Key Laboratory for Agricultural Soil and Water Engineering in Arid Area of Ministry of Education Northwest A&F UniversityYangling 712100ShaanxiChina

Accurate irrigation and nitrogen application are essential for promoting the growth and yield of cherry *** investigating the effects of irrigation and nitrogen on the growth,photosynthesis,and yield of cherry tomatoes,nine treatments including three levels of both irrigation and nitrogen were conducted over two growing *** stem diameter and horizontal stem diameter had the best performance at the irrigation level of 75%evaporation(E_(p)),although their responses to nitrogen were different for the two *** height increased with the increase of irrigation and *** dry matter(PDM)was significantly affected by irrigation and nitrogen *** lowest PDM was found in the highest proportion of root dry matter,which occurred under low nitrogen *** net photosynthetic rate(Pn)and transpiration rate enhanced with the increase of *** nitrogen showed promotion effect on all photosynthetic parameters in both growing *** of all fourteen indicators showed significant correlations with ***,single plant fruit number and PDM in 2018 Fall had significant positive direct effects on yield with the path coefficients of 0.648 and 1.159,while the significant direct path coefficients were 0.362 and 0.294 in Fruit dry matter and Pn for 2019 Spring,*** on the comprehensive evaluation of growth and yield by TOPSIS,the irrigation level of 75%E_(p) combined with medium nitrogen application produced higher yields by promoting the growth and photosynthesis of cherry *** provides a strategy for water and nitrogen management of cherry tomatoes in Northwest China.

关键词： cherry tomatoes yield growth irrigation nitrogen path analysis

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Fast detection of the early decay in oranges using visible-LED structuredillumination imaging combined with spiral phase transform and feature-based classification model

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International Journal of Agricultural and Biological Engineering 2024年第3期17卷 185-192,F0003页

作者： Zhonglei cai Chanjun Sun Yizhi zhang Ruiyao Shi Junyi zhang Hailiang zhang Jiangbo Li College of Mechanical and Electrical Engineering Shihezi UniversityShihezi 832003XinjiangChina Jiangsu Province and Education Ministry Co-sponsored Synergistic Innovation Center of Modern Agricultural Equipment Jiangsu UniversityZhenjiang 212013JiangsuChina Intelligent Equipment Research Center Beijing Academy of Agriculture and Forestry SciencesBeijing100097China College of Electrical and Automation Engineering East China Jiaotong UniversityNanchang 330013China National Engineering Research Center for Information Technology in Agriculture Beijing 100089China

The early decay of citrus can cause economic and serious food safety *** early decayed area has no obvious visual characteristics,making effective detection of this damage very difficult for the citrus *** study constructed a new detection system based on visible-light emitting diode(LED)structured-illumination imaging and proposed an effective methodology combined with a spiral phase transform(SPT)algorithm for the early detection of decayed *** sample obtained three phase-shifting pattern images with phase shifts of−2π/3,0,and 2π/3 at a spatial frequency of 0.25 cycles/*** strategies(i.e.,the conventional three-phase-shifting method,2-phase SPT,and 1-phase SPT)were used to demodulate the original patterned images to recover the direct component(DC)and amplitude component(AC)*** partial least squares discriminant analysis(PLS-DA)and least squares support vector machine(LS-SVM)classification models were established based on the texture features of DC,AC,and RT(*** ratio of AC to DC)***,the random frog(RF)algorithm was used to simplify the optimal full-featured ***,the LS-SVM model constructed using 7 texture features from the RT image obtained an average classification accuracy of 95.1%for all tested *** study indicates that the proposed structured-illumination imaging technique combined with 2-phase SPT and feature-based classification model can achieve the fast identification of early decayed oranges.

关键词： oranges early decay detection structured-illumination imaging spiral phase transform classification model

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OcBSA:An NGS-based bulk segregant analysis tool for outcross populations

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Molecular Plant 2024年第4期17卷 648-657页

作者： Lingkui zhang Yanfeng Duan Zewei zhang Lei zhang Shumin Chen Chengcheng cai Shaoguang Duan Kang zhang guangcun Li Feng Cheng State Key Laboratory of Vegetable Biobreeding Key Laboratory of Biology and Genetic Improvement of Horticultural Crops of the Ministry of Agriculture and Rural AffairsKey Laboratory of Biology and Genetic Improvement of Tuber and Root Crop of Ministry of Agriculture and Rural AffairsSino-Dutch Joint Laboratory of Horticultural GenomicsInstitute of Vegetables and FlowersChinese Academy of Agricultural SciencesBeijing 100081China

Constructing inbred lines for self-incompatible species and species with long generation times is challenging,making the use of F1 outcross/segregating populations the main strategy for genetic studies of such ***,there is a lack of dedicated algorithms/tools for rapid quantitative trait locus(QTL)mapping using the F1 *** this end,we have designed and developed an algorithm/tool called OcBSA specifically for QTL mapping of F1 *** transforms the four-haplotype inheritance problem from the two heterozygous diploid parents of the F1 population into the two-haplotype inheritance problem common in current genetic studies by removing the two haplotypes from the heterozygous parent that do not contribute to phenotype segregation in the F1 *** of OcBSA on 1800 simulated F1 populations demonstrated its advantages over other currently available tools in terms of sensitivity and *** addition,the broad applicability of OcBSA was validated by QTL mapping using seven reported F1 populations of apple,pear,peach,citrus,grape,tea,and *** also used OcBSA to map the QTL for flower color in a newly constructed F1 population of potato generated in this *** OcBSA mapping result was verified by the insertion or deletion markers to be consistent with a previously reported locus harboring the ANTHOCYANIN 2 gene,which regulates potato flower *** together,these results highlight the power and broad utility of OcBSA for QTL mapping using F1 populations and thus a great potential for functional gene mining in outcrossing *** ease of use,we have developed both Windows and Linux versions of OcBSA,which are freely available at:https://***/Bioinformaticslab/OcBSA.

关键词： outcross BSA self-incompatible F1 population QTL mapping potato

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