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Boundary Points,Minimal L^(2)Integrals and Concavity PropertyⅢ—Linearity on Riemann Surfaces and Fibrations over Open Riemann Surfaces

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2091-2152页

作者： Qi An guan Zhi Tong MI Zheng yuan School of Mathematical Sciences Peking UniversityBeijing 100871P.R.China School of Mathematics and Statistics Beijing Jiaotong UniversityBeijing 100044P.R.China Institute of Mathematics Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190P.R.China

In this article,we.consider a modified version of minimal L^(2) integrals on sublevel sets of plurisubharmonic functions related to modules at boundary points,and obtain a concavity property of the modified *** applications,we.give characterizations for the concavity degenerating to linearity on open Riemann surfaces and on fibrations over open Riemann surfaces.

关键词： Minimal L^(2)integrals plurisubharmonic functions boundary points we.kly pseudoconvex Kähler manifold

Lactate metabolism in neurodegenerative diseases

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Neural Regeneration Research 2024年第1期19卷 69-74页

作者： Chaoguang Yang Rui-yuan Pan Fangxia guan Zengqiang yuan The Brain Science Center Beijing Institute of Basic Medical SciencesBeijingChina School of Life Sciences Zhengzhou UniversityZhengzhouHenan ProvinceChina

Lactate,a byproduct of glycolysis,was thought to be a metabolic waste until the discovery of the Warburg *** not only functions as a metabolic substrate to provide energy but can also function as a signaling molecule to modulate cellular functions under pathophysiological *** Astrocyte-Neuron Lactate Shuttle has cla rified that lactate plays a pivotal role in the central nervous ***,protein lactylation highlights the novel role of lactate in regulating transcription,cellular functions,and disease *** review summarizes the recent advances in lactate metabolism and its role in neurodegenerative diseases,thus providing optimal pers pectives for future research.

关键词： Alzheimer's disease Astrocyte-Neuron Lactate Shuttle brain central nervous system glucose metabolism glycolysis neuroinflammation Parkinson's disease protein lactylation signaling molecule

FUSE: a federated learning and U-shape split learning-based electricity theft detection framework

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Science China(Information Sciences) 2024年第4期67卷 339-340页

作者： Xuan LI Naiyu WANG Liehuang ZHU Shuai yuan Zhitao guan School of Control and Computer Engineering North China Electric Power University School of Cyberspace Science and Technology Beijing Institute of Technology Department of Finance Operationsand Information Systems(FOIS)Brock University

In recent years, the data-driven electricity theft detection methods integrated with edge cloud computing [1, 2] have not only demonstrated superior detection accuracy but also improved efficiency, making them viable alternatives to indoor inspections. Energy service providers(ESPs) typically manage regions by dividing them into various transformer districts(TDs). The detection of electricity theft in a particular region is performed by the associated TD,

关键词： Sensitive data

Alkyl chain modulation of asymmetric hexacyclic fused acceptor synergistically with wide bandgap third component for high efficiency ternary organic solar cells

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International Journal of Minerals,Metallurgy and Materials 2024年第7期31卷 1713-1719页

作者： Shufang Li Huilan guan Can Zhu Chaoyuan Sun Qingya we. Jun yuan Yingping Zou College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083China Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Organic SolidsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China Institute of Carbon Neutrality and New Energy School of Electronics and InformationHangzhou Dianzi UniversityHangzhou 310018China

Herein,two asymmetric hexacyclic fused small molecule acceptors(SMAs),namely BP4F-HU and BP4F-UU,we.e *** elongated outside chains in the BP4F-UU molecule played a crucial role in optimizing the morphology of blend film,thereby improving charge mobility and reducing energy loss within the corresponding ***,the PM6:BP4F-UU device exhibited a higher open-circuit voltage(V_(oc))of 0.878 V compared to the PM6:BP4F-HU device with a V_(oc)of 0.863 ***,a new wide bandgap SMA named BTP-TA was designed and synthesized as the third component to the PM6:BP4F-UU host binary devices,which showe. an ideal complementary absorption spectrum in PM6:BP4F-UU *** addition,BTP-TA can achieve efficient intermolecular energy transfer to BP4F-UU by fluorescence resonance energy transfer(FRET)pathway,due to the good overlap betwe.n the photoluminescence(PL)spectrum of BTP-TA and the absorption region of ***,ternary devices with 15wt%BTP-TA exhibits broader photon utilization,optimal blend morphology,and reduced charge recombination compared to the corresponding binary ***,PM6:BP4F-UU:BTP-TA ternary device achieved an optimal powe. conversion efficiency(PCE)of 17.83%with simultaneously increased V_(oc)of 0.905 V,short-circuit current density(J_(sc))of 26.14 mA/cm^(2),and fill factor(FF)of 75.38%.

关键词： asymmetric hexacyclic acceptor outside chain wide bandgap acceptor ternary organic solar cells

Effect of Mn addition on microstructure and mechanical properties of GX40CrNiSi25-12 austenitic heat resistant steel

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China Foundry 2024年第3期21卷 205-212页

作者： guan-yu Jiang Meng-wu Wu Xiao-guang Yang Hui Wang Yu-yuan Zhu Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Longzhong Laboratory Xiangyang 441000HubeiChina we.cast Industries(China)Co. Ltd.Wuhan 430100China

Three types of steels we.e designed on the basis of GX40CrNiSi25-12 austenitic heat resistant steel by adding different Mn contents(2wt.%,6wt.%,and 12wt.%).Thermodynamic calculation,microstructure characterization and mechanical property tests we.e conducted to investigate the effect of Mn addition on the microstructure and mechanical properties of the austenitic heat resistant *** show that the matrix structure in all the three types of steels at room temperature is completely *** NbC and M_(23)C_(6)precipitate at grain boundaries of austenite *** the increase of Mn content,the number of carbides increases and their distribution becomes more *** the Mn content increases from 1.99%to 12.06%,the ultimate tensile strength,yield strength and elongation increase by 14.6%,8.0%and 46.3%,*** improvement of the mechanical properties of austenitic steels can be explained by utilizing classic theories of alloy strengthening,including solid solution strengthening,precipitation strengthening,and grain *** increase in alloy strength can be attributed to solid solution strengthening and precipitation strengthening caused by the addition of *** improvement of the plasticity of austenitic steels can be explained from two aspects:grain refinement and homogenization of precipitated phases.

关键词： austenitic heat resistant steel manganese microstructure mechanical properties

Automated and controlled patch generation for enhanced fixing of communication software vulnerabilities

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Intelligent and Converged Networks 2024年第3期5卷 222-236页

作者： Shuo Feng Shuai yuan Zhitao guan Xiaojiang Du School of Control and Computer Engineering North China Electric Power UniversityBeijing 100029China Department of Finance Operationsand Information SystemsBrock UniversitySt.Catharines L2S3A1Canada Department of Electrical and Computer Engineering Stevens Institute of TechnologyHobokenNJ 07030USA

Software is a crucial component in the communication systems,and its security is of paramount ***,it is susceptible to different types of attacks due to potential ***,significant time and effort is required to fix such *** propose an automated program repair method based on controlled text generation ***,we.utilize a fine-tuned language model for patch generation and introduce a discriminator to evaluate the generation process,selecting results that contribute most to vulnerability ***,we.perform static syntax analysis to expedite the patch verification *** effectiveness of the proposed approach is validated using QuixBugs and Defects4J datasets,demonstrating significant improvements in generating correct patches compared to other existing methods.

关键词： automatic program repair controlled text generation communication software security program language model

Exploring treatment options in cancer: Tumor treatment strategies

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3337-3380页

作者： Beilei Liu Hongyu Zhou Licheng Tan Kin To Hugo Siu Xin-yuan guan Department of Clinical Oncology The University of Hong Kong-Shenzhen HospitalShenzhenChina Department of Clinical Oncology The University of Hong KongHong KongChina state Key Laboratory for Liver Research The University of Hong KongHong KongChina Advanced Energy Science and Technology guangdong Laboratory HuizhouChina MOE Key Laboratory of Tumor Molecular Biology Jinan UniversityGuangzhouChina

Traditional therapeutic approaches such as chemotherapy and radiation therapy have burdened cancer patients with onerous physical and psychological ***,the landscape of tumor treatment has undergone a comprehensive and remarkable *** as fervently pursued modalities are small molecule targeted agents,antibody-drug conjugates(ADCs),cell-based therapies,and gene *** cutting-edge treatment modalities not only afford personalized and precise tumor targeting,but also provide patients with enhanced therapeutic comfort and the potential to impede disease ***,it is acknowledged that these therapeutic strategies still harbour untapped potential for further *** a comprehensive understanding of the merits and limitations of these treatment modalities holds the promise of offering novel perspectives for clinical practice and foundational research *** this review,we.discussed the different treatment modalities,including small molecule targeted drugs,peptide drugs,antibody drugs,cell therapy,and gene *** will provide a detailed explanation of each method,addressing their status of development,clinical challenges,and potential *** aim is to assist clinicians and researchers in gaining a deeper understanding of these diverse treatment options,enabling them to carry out effective treatment and advance their research more effciently.

关键词： drugs treatment holds

Further study on the genesis of lamellar calcite veins in lacustrine black shale--A case study of Paleogene in Dongying Depression, China

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Petroleum Science 2024年第3期21卷 1508-1523页

作者： guan-Min Wang Yun-Jiao Zhang Zi-yuan Yin Rui Zhu Zhi-Yao Hou Yu Bai School of Geosciences China University of Petroleum(East China)Qingdao266580ShandongChina

Lamellar calcite veins are prevalent in carbonate-rich,lacustrine dark *** formation mechanisms of these veins have been extensively debated,focusing on factors such as timing,depth,material source,and driving *** paper examines dark lacustrine shale lamellar calcite veins in the Paleogene strata of Dongying Depression,using various analytical techniques:petrography,isotope geochemistry,cathodoluminescence,inclusion thermometry,and electron probe *** distinct types of calcite veins have been identified:granular calcite veins and sparry calcite *** two types differ significantly in color,grain structure,morphology,and *** further investigation,it was observed that vein generation occurred from the shallow burial period to the maturation of organic matter,with a transition from granular calcite veins to sparry calcite *** granular calcite veins exhibit characteristics associated with the shallow burial period,including plastically deformed laminae and veins,the development of strawberry pyrite,the absence of oil and gas,we.k fractionation in oxygen isotopes,and their contact relationship with sparry calcite *** granular calcite veins we.e likely influenced by the reduction of sulfate *** the other hand,sparry calcite veins with fibrous grains are antitaxial and closely linked to the evolution and maturation of organic *** contain oil and gas inclusions and show a distribution range of homogenization temperature betwe.n 90℃ and 120℃ and strong fractionation in oxygen isotopes,indicating formation during the hydrocarbon expulsion *** carbon isotope analysis of the surrounding rocks and veins suggests that the material for vein formation originates from the shale itself,specifically authigenic micritic calcite modified by the action of *** opening of horizontal fractures and vein formation is likely driven by fluid overpressure resulting from undercompaction and hydrocarb

关键词： Calcite veins Shale diagenesis Material source Formation period Formation mechanism

Data-driven casting defect prediction model for sand casting based on random forest classification algorithm

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China Foundry 2024年第2期21卷 137-146页

作者： Bang guan Dong-hong Wang Da Shu Shou-qin Zhu Xiao-yuan Ji Bao-de Sun Shanghai Key Lab of Advanced High-Temperature Materials and Precision Forming School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China State Key Lab of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240China Hefei Casting and Forging Factory of Anhui Heli Co. LtdHefei 230000China State Key Laboratory of Materials Processing and Die&Mould Technology Huazhong University of Science and TechnologyWuhan 430074China

The complex sand-casting process combined with the interactions betwe.n process parameters makes it difficult to control the casting quality,resulting in a high scrap rate.A strategy based on a data-driven model was proposed to reduce casting defects and improve production efficiency,which includes the random forest(RF)classification model,the feature importance analysis,and the process parameters optimization with Monte Carlo *** collected data includes four types of defects and corresponding process parameters we.e used to construct the RF *** results show a recall rate above 90% for all *** Gini Index was used to assess the importance of the process parameters in the formation of various defects in the RF ***,the classification model was applied to different production conditions for quality *** the case of process parameters optimization for gas porosity defects,this model serves as an experimental process in the Monte Carlo method to estimate a better temperature *** prediction model,when applied to the factory,greatly improved the efficiency of defect *** show that the scrap rate decreased from 10.16% to 6.68%.

关键词： sand casting process data-driven method classification model quality prediction feature importance