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Who benefits from RO resection?A single-center analysis of patients with stage Ⅳ gallbladder cancer

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Chronic Diseases and Translational Medicine 2019年第3期5卷 188-196页

作者： Chen Chen Lin Wang Rui zhang Qi Li Ya-Ling Zhao guan-jun zhang Wen-Zhi Li Zhi-Min Geng Department of Hepatobiliary Surgery First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxi 710061China Department of Geriatric Surgery First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxi 710061China Department of Epidemiology and Biostatistics School of Public HealthXi'an Jiaotong University Health Science CenterXi'anShaanxi 710061China Department of Pathology First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxi 710061China

Objectives:Most patients with gallbladder cancer(GBC)present with advanced-stage disease and have a poor *** resection remains the only therapeutic option to improve survival in patients with *** study aimed to analyze the prognostic factors in patients with stageⅣGBC and to identify a subgroup of patients who might benefit from RO ***:A total of 285 patients with stageⅣGBC were retrospectively analyzed at our institution from January 2008 to December *** potentially influencing the prognosis of GBC after surgery were analyzed by univariate and multivariate ***:The 1-,3-,and 5-year overall survival rates were 6.6%(15/229),0.9%(2/229),and 0(0/229),***(relative risk[RR]=1.631,95%confidence interval[C/]:1.221-2.180,P=0.001),pathological grade(RR=1.337,95%Cl:1.050-1.702,P=0.018),T stage(RR=1.421,95%Cl:1.099-1.837,P=0.000),M stage(RR=1.896,95%Cl:1.409-2.552,P=0.000),and surgery(RR=1.542,95%Cl:1.022-2.327,P=0.039)were identified as independent risk factors influencing *** median survival time(MST)was significantly higher in patients undergoing R0 resection than in those undergoing R1/R2 resection(6.0 vs.2.7 months;P<0.001).In subgroup analyses,stage IVA patients benefited from R0 resection(MST for R0 vs.R1/R2,11.0 vs.4.0 months;P=0.003),while R0 resection had a significant survival benefit than R1/R2 resection in patient with stage IVB GBC without distant metastasis(MST for R0 vs.R1/R2,6.0 vs.3.0 months;P=0.007).Conclusion:Ascites,pathological grade,T stage,M stage,and surgery were independent risk factors influencing prognosis in patients with stageⅣGBC.N2 lymph node metastasis did not preclude curative resection,and radical resection should be considered in patients with stageⅣGBC without distant metastasis once R0 margin was achieved.

关键词： Gallbladder cancer Surgery Prognosis Tumor-node-metastasis(TNM)stage

Research on Oxidative Stress in Melanoma Cancer Cells Induced by He Plasma Jet

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Research on Oxidative Stress in Melanoma Cancer Cells Induce...

Inhibiting Effects of Hydrogen Peroxide Induced by Low Temperature Plasma on Melanoma Cells

第十八届全国等离子体科学技术会议

作者： Gui-min Xu guan-jun zhang Jin-ren Liu Xing-min Shi State Key Laboratory of Electrical Insulation and Power Equipment School of Electrical EngineeringXi'an Jiaotong University Environment and Genes Related to Diseases Key Laboratory of Education Ministry School of Public HealthXi'an Jiaotong University

Atmospheric pressure cold plasma that contains numerous active components including electrons,ions and free radicals has been extensively researched as a promising anticancer treatment technology in recent *** is the most aggressive form of skin cancer with a high prevalence,a median overall survival of less than 2 years,and resistance to current modalities of cancer *** this work,an atmospheric pressure plasma jet(APPJ) with three electrodes in helium is utilized for treatment of murine melanoma caner cells and the oxidative stress in cells is *** a series of biological assay,it is showed that cell viability is decreased,the intracellular total antioxidant capability(T-AOC),malondialdehyde(MDA),reactive oxygen species(ROS) content and degree of DNA damage are increased in a time-dependent manner with10,30,60 s and 90 s plasma treatment compared with the control ***,cell cycle is arrested in G1 phase significantly after plasma *** pre-treatment of cell culture medium with N-acetylcysteine(NAC,which is a free radical scavenger),the decrease in cell viability,the increase of intracellular T-AOC,MDA,ROS content and degree of DNA damage can be prevented after plasma *** results suggest that plasma exerted cytotoxic effects by causing oxidative stress-induced damage to cellular components.

关键词： Oxidative Stress Melanoma Plasma Jet

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Inhibiting Effects of Hydrogen Peroxide Induced by Low Tempe...

天线匹配对莱斯信道下紧凑MIMO系统性能的影响

第十八届全国等离子体科学技术会议

作者： Jin-ren Liu Xing-min Shi Gui-min Xu guan-jun zhang Environment and Genes Related to Diseases Key Laboratory of Education Ministry School of Public Health State Key Laboratory of Electrical Insulation and Power Equipment School of Electrical Engineering

The potential application of low temperature plasma(LTP) in anticancer has attracted great attention from *** mechanism of plasma anticancer action may be related to the reactive oxygen and nitrogen oxygen species generated by *** aim of this study is to identify the inhibiting effects of hydrogen peroxide(H2 O2) induced through plasma-medium interaction on B16 melanoma cells cultured in *** this purpose,helium plasma jet is used to irradiate medium with different time,thereby generating plasma-activated medium(PAM),which is applied to the cancer cells ***(CAT) is added into PAM to degrade H2 O2 as intervention groups and pure H2 O2 is added into fresh medium as positive *** content of H2 O2 in medium and cell,cell morphology,cell viability,cell cycle distribution,apoptosis and DNA damage are detected with coumarin boronic acid fluorescence probe,inverted biological microscope observation,3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay,flow cytometry,single cell geleletrophoresis and 8-hydroxy-2-deoxyguanosine(8-OHd G)ELISA kit,*** results show that the content of H2 O2 in PAM increases with prolongation of LTP treatment time after incubation for 0 h and 24 ***,the intracellular content does not change *** assay reveals that the PAM of 75 s treatment causes48.3% growth inhibition,but the rate of that with CAT intervention and H2 O2 group are 13.4%and 41.2%,*** cell morphology results show that the degree of cell damage in 75 s PAM group is equal with the cells in H2 O2 group,whereas the cells in CAT intervention group are *** cytometer results show that compared with control group,PAM with longer treatment times and pure H2 O2 can cause more cell arresting in G1 phase and *** CAT can prevent these changes in cell cycle and cell *** cell geleletrophoresis and8-OHd G assay show that CAT can protect DNA from H2 O2 ***

关键词： low temperature plasma the reactive oxygen and nitrogen oxygen species

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电波科学学报 2009年第6期24卷 1009-1013页

作者：郭强周希朗张唯炯管张均上海交通大学电子工程系上海200240

深入研究了存在天线互耦和空间相关时,天线匹配网络对莱斯信道下多输入多输出MIMO系统性能的影响,建立了包含相关莱斯信道、天线互耦和匹配网络的(MIMO)系统模型。通过仿真分析了匹配阻抗、天线互耦、空间相关性以及信道衰落环境对包络... 详细信息

深入研究了存在天线互耦和空间相关时,天线匹配网络对莱斯信道下多输入多输出MIMO系统性能的影响,建立了包含相关莱斯信道、天线互耦和匹配网络的(MIMO)系统模型。通过仿真分析了匹配阻抗、天线互耦、空间相关性以及信道衰落环境对包络相关性和信道容量的影响。实验结果表明:莱斯信道下匹配阻抗对MIMO系统的影响与瑞利信道情况下有所不同,适当地选择天线匹配阻抗可以改善MIMO系统的性能。

关键词：多输入多输出天线匹配莱斯信道空间相关互耦

From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua Lu jun Shen Xin zhang Lingcong Chao Liang Chen Ding zhang Tao Wei Shoudong Xu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added

一种低复杂度的水声OFDM通信系统子载波分配算法

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计算机科学 2021年第S1期48卷 387-391页

作者：尤凌管张均上海海事大学计算机科学系上海201306 上海海事大学电子工程系上海201306

近年来,随着国家"智慧海洋"战略的推进,以及海洋资源开发的需求,基于OFDM调制的水声通信技术得到了飞速发展,其关键问题之一就是主节点如何分配子载波资源以优化系统性能。据此,提出了一种低复杂度的水声OFDM子载波分配算法,以某个准则... 详细信息

近年来,随着国家"智慧海洋"战略的推进,以及海洋资源开发的需求,基于OFDM调制的水声通信技术得到了飞速发展,其关键问题之一就是主节点如何分配子载波资源以优化系统性能。据此,提出了一种低复杂度的水声OFDM子载波分配算法,以某个准则挑选出每轮待分配的候选节点,选择综合信道状态最差的节点分配子载波,在提高系统整体传输性能的同时兼顾了最差传感器节点的传输性能。此外,针对多轮分配的连续轮空现象,优先为上轮的"空闲"节点分配其上信道状况最好的子载波。仿真结果表明,改进的算法在几乎不降低原算法性能的前提下较好地解决了连续轮空的问题。算法的提出对水下多传感器组网的资源分配有一定的参考意义。

关键词：水声通信正交频分复用子载波分配信道状态信息计算复杂度

Dielectric-ion-conductive ZnNb2O6 layer enabling rapid desolvation and diffusion for dendrite-free Zn metal batteries

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Journal of Energy Chemistry 2025年第1期100卷 693-701页

作者： Haifeng Yang Jian Wang Panpan zhang Xiaomin Cheng Qinghua guan Jing Dong Bixian Chen Lujie Jia Jing zhang Yongzheng zhang Yunjian Liu Hongzhen Lin School of Materials Science and Engineering Jiangsu University i-Lab & CAS Key Laboratory of Nanophotonic Materials and Devices Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Helmholtz Institute Ulm (HIU) Karlsruhe Institute of Technology (KIT) School of Materials Science and Engineering Xi'an University of Technology State Key Laboratory of Chemical Engineering East China University of Science and Technology

Rechargeable aqueous zinc-metal batteries （AZMBs） are promising candidates for large-scale energy storage systems due to their low cost and high ***,their performance and sustainability are significantly hindered by the sluggish desolvation kinetics at the electrode/electrolyte interface and the corresponding hydrogen evolution reaction where active water molecules tightly participate in the Zn（H2O）62+solvation ***,learnt from self-generated solid electrolyte interphase （SEI） in anodes,the dielectric but ion-conductive zinc niobate nanoparticles artificial layer is constructed on metallic Zn surface （ZNB@Zn）,acting as a rapid desolvation *** zincophilic and dielectric-conductive properties of ZNB layer accelerate interfacial desolvation/diffusion and suppress surface corrosion or dendrite formation,achieving uniform Zn plating/stripping behavior,as confirmed by electronic/optical microscopies and interface spectroscopical measurements together with theoretical ***,the as-prepared ZNB@Zn electrode exhibits excellent cycling stability of over 2000 h and robust reversibility （99.54%） even under high current density and depth of discharge ***,the assembled ZNB@Zn-based full cell displays high capacity-retention rate of 80.21%after 3000 cycles at 5 A g-1and outstanding rate performance up to 10 A *** large-areal pouch cell is stabilized for hundreds of cycles,highlighting the bright prospects of the dielectric but ion-conductive layer in further application of AZMBs.

关键词： Zn metal battery Dielectric artificial layer Rapid ion diffusion Zincophilic diffusion Active water inhibition

特殊非Rayleigh相关信道的MIMO-MRC系统性能

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应用科学学报 2009年第6期27卷 557-562页

作者：张唯炯管张均周希朗上海交通大学电子工程系上海200240

基于矩阵变量复超几何函数的性质,提出一种分析低Rician因子信道下MIMO-MRC系统性能的近似方法.该方法利用非中心复Wishart矩阵有序特征值概率密度函数的上界得到最大特征值的近似概率密度函数,据此求得Rician信道下发射相关MIMO-MRC系... 详细信息

基于矩阵变量复超几何函数的性质,提出一种分析低Rician因子信道下MIMO-MRC系统性能的近似方法.该方法利用非中心复Wishart矩阵有序特征值概率密度函数的上界得到最大特征值的近似概率密度函数,据此求得Rician信道下发射相关MIMO-MRC系统的中断容量、平均信噪比及误符号率等性能的封闭表达式.此外还研究了发射相关Nakagami锁孔信道下MIMO-MRC系统信噪比的概率密度函数,并求得系统平均信噪比的封闭表达式.与已有结果相比,所得到的公式更易于计算.仿真结果验证了推导的正确性.

关键词：多输入多输出最大比合并非Rayleigh信道空间相关复超几何函数

基于容量最大化的多用户MIMO-OFDM子载波分配算法

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电讯技术 2011年第9期51卷 127-130页

作者：管张均周希朗上海交通大学电子工程系上海200240

针对多用户MIMO-OFDM通信网络,提出了一种基于系统和容量最大化的子载波分配算法。通过对MIMO-OFDM系统和容量公式进行分析,提取出子载波分配的判决参数,再利用匈牙利算法对子载波进行分配,同时分析了分配后系统平均容量的统计特性。为... 详细信息

针对多用户MIMO-OFDM通信网络,提出了一种基于系统和容量最大化的子载波分配算法。通过对MIMO-OFDM系统和容量公式进行分析,提取出子载波分配的判决参数,再利用匈牙利算法对子载波进行分配,同时分析了分配后系统平均容量的统计特性。为了兼顾公平,又提出了传输速率最小的用户传输速率最大化的子载波分配算法。仿真结果表明,所提容量最大化算法能使系统和容量达到全局最大值,且具有较低的复杂度。

关键词： MIMO-OFDM 子载波分配匈牙利算法容量最大化