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Experiment and finite element method analysis mass erosion and transfer of Ag/La_2NiO_4-based electrical contacts during operation

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Rare Metals 2013年第1期32卷 93-99页

作者： Song Chen Wei-ming guan Kun-Hua Zhang Zhi-Long Tan ming Xie Kunming Institute of Precious Metals State Key Laboratory of Advanced Technologies for Comprehensive Utilization of Platinum Metals

A uniform transient temperature field model of electrical contacts operation was found by analyzing the process of closing arc constriction resistance Joule heat ~ breaking arc. Essential parameters of Ag/La2NiO4 electrical contact material for transient temperature field calculation were obtained through tests of electrical contact experimental instrument under 18 V DC in different cur- rents, other correlation experiments, and calculation anal- ysis. The finite element method was applied to solve the transient temperature field, and the features and distribution of the transient temperature field were obtained. The condition of material erosion and mass transfer can be forecasted by those calculation results. It is beneficial to research about the lifetime of Ag/La2NiO4 electrical material.

关键词： Electrical contact Finite element Mass transfer Erosion Temperature field model

Diesel molecular composition and blending modeling based on SUBEM framework

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Petroleum Science 2022年第2期19卷 839-847页

作者： Yue-ming guan Dong guan Cheng Zhang Sheng-Hua Yuan guang-Qing Cai Lin-Zhou Zhang State Key Laboratory of Heavy Oil Processing Petroleum Molecular Engineering Center(PMEC)China University of PetroleumBeijing102249China SINOPEC Dalian Research Institute of Petroleum and Petrochemicals SINOPECDalian116045LiaoningChina

Diesel molecular compositional model has important application for diesel quality prediction,blending,and molecular-level process model *** this paper,different types of diesel molecular compositional and blending models were constructed based on the SU-BEM *** than 1500 representative molecules were selected to form the molecular structure *** probability density functions(PDFs)combination was determined by experimental data and experience.A quadratic optimization strategy combining genetic algorithm with local optimization algorithm was adopted to improve the accuracy of the compositional *** model results show good agreement with the experimental *** diesel blending model was constructed at the molecular-level based on the above diesel compositional *** properties of the blending model accord with the experimental *** is proved that the compositional models and blending model constructed have high accuracy and strong prediction capability,and are applicable to the industrial process.

关键词： Molecular compositional model Molecular blending model SU-BEM Framework Diesel

Yield of long-lived fission product transmutation using proton-, deuteron-, and alpha particle-induced spallation

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Nuclear Science and Techniques 2021年第9期32卷 73-83页

作者： Meng-Ting Jin Su-Yang Xu guan-ming Yang Jun Su Sino-French Institute for Nuclear Energy and Technology Sun Yat-sen UniversityZhuhai 519082China

The transmutation of long-lived fission products through spallation induced by light nuclides was investi-gated for the purpose of determining the feasibility of this approach for long-lived fission products,in both economic and environmental *** cross-section data were obtained from the TALYS Evaluated Nuclear Data Library(TENDL).A thick target model was used to study the consumption of the target isotopes in the transmutation *** transmutation yield was calculated using the highest beam intensity available with the China initiative accelerator-driven *** was found that the light nuclide-induced spallation reaction can significantly reduce the radio toxicity of the investigated long-lived fission *** the transmutation target made of elemental LLFP and the proton beam with an intensity of 5 mA,the consumption of 90 Sr,93 Zr,107 Pd,or 137 Cs can reach approximately 500 g per year.

关键词： Transmutation Long-lived fission products Spallation

Influence of screw length and diameter on tibial strain energy density distribution after anterior cruciate ligament reconstruction

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Acta Mechanica Sinica 2014年第2期30卷 241-249页

作者： Jie Yao guan-ming Kuang Duo Wai-Chi Wong Wen-Xin Niu ming Zhang Yu-Bo Fan Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education School of Biological Science and Medical Engineering/National Key Lab of Virtual Reality TechnologyBeihang University Interdisciplinary Division of Biomedical Engineering Faculty of EngineeringThe Hong Kong Polytechnic University Shenzhen Key Laboratory for Innovative Technology in Orthopaedic Trauma Department of Orthopaedics and TraumatologyThe University of Hong Kong-Shenzhen Hospital The University of Hong Kong Tongji University School of Medicine

Postoperative tunnel enlargement has been frequently reported after anterior cruciate ligament（ACL）*** screw,as a surgical implant in ACL reconstruction,may influence natural loading transmission and contribute to tunnel *** aims of this study are（1）to quantify the alteration of strain energy density（SED）distribution after the anatomic single-bundle ACL reconstruction;and（2）to characterize the influence of screw length and diameter on the degree of the SED alteration.A validated finite element model of human knee joint was *** screw length ranging from 20 to 30 mm with screw diameter ranging from 7 to 9 mm were *** the post-operative knee,the SED increased steeply at the extra-articular tunnel aperture under compressive and complex loadings,whereas the SED decreased beneath the screw shaft and nearby the intra-articular tunnel *** the screw length could lower the SED deprivation in the proximal part of the bone tunnel;whereas increasing either screw length or diameter could aggravate the SED deprivation in the distal part of the bone *** the elastic modulus of the screw could lower the bone SED deprivation around the *** consideration of both graft stability and SED alteration,a biodegradable interference screw with a long length is recommended,which could provide a beneficial mechanical environment at the distal part of the tunnel,and meanwhile decrease the bone-graft motion and synovial fluid propagation at the proximal part of the *** findings together with the clinical and histological factors could help to improve surgical outcome,and serve as a preliminary knowledge for the following study of biodegradable interference screw.

关键词： Anterior crucial ligament reconstruction Strain energy density Screw length Screw diameter

Biochanin A attenuates spinal cord injury in rats during early stages by inhibiting oxidative stress and inflammasome activation

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Neural Regeneration Research 2024年第9期19卷 2050-2056页

作者： Xigong Li Jing Fu ming guan Haifei Shi Wenming Pan Xianfeng Lou Department of Orthopedics The First Affiliated Hospital of Zhejiang UniversityHangzhouZhejiang ProvinceChina Department of Stomatology Xixi HospitalHangzhouZhejiang ProvinceChina Department of Orthopedics and Spine Surgerythe Affiliated Hospital of Xuzhou Medical Schoolthe Second People’s Hospital of ChangshuChangshuJiangsu ProvinceChina

Previous studies have shown that Biochanin A,a flavonoid compound with estrogenic effects,can serve as a neuroprotective agent in the context of cerebral ischemia/reperfusion injury;howeve r,its effect on spinal cord injury is still unclea r. In this study,a rat model of spinal cord injury was established using the heavy o bject impact method,and the rats were then treated with Biochanin A(40 mg/kg) via intrape ritoneal injection for 14 consecutive *** res ults showed that Biochanin A effectively alleviated spinal cord neuronal injury and spinal co rd tissue injury,reduced inflammation and oxidative stress in spinal cord neuro ns,and reduced apoptosis and *** addition,Biochanin A inhibited the expression of inflammasome-related proteins(ASC,NLRP3,and GSDMD)and the Toll-like receptor 4/nuclear factor-κB pathway,activated the Nrf2/heme oxygenase 1 signaling pathway,and increased the expression of the autophagy markers LC3 Ⅱ,Beclin-1,and *** r,the therapeutic effects of Biochanin A on early post-s pinal cord injury were similar to those of *** findings suggest that Biochanin A protected neurons in the injured spinal cord through the Toll-like receptor 4/nuclear factor κB and Nrf2/heme oxygenase 1 signaling *** findings suggest that Biochanin A can alleviate post-spinal cord injury at an early stage.

关键词： apoptosis autophagy Biochanin A heme oxygenase 1 inflammation Nrf2 protein nuclear factor kappa-B oxidative stress spinal cord injury Toll-like receptor 4

Advanced materials for aqueous supercapacitors in the asymmetric design

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Progress in Natural Science:Materials International 2015年第6期25卷 527-544页

作者： Muniyandi Rajkumar Chun-Tsung Hsu Tzu-Ho Wu ming-guan Chen Chi-Chang Hu Laboratory of Electrochemistry and Advanced Materials Department of Chemical EngineeringNational Tsing Hua University

Supercapacitors have been recognized as one of the promising energy storage devices in the future energy *** this perspective,rapid progress is made in the development of fundamental and applied aspects of *** techniques have been developed specifically to estimate the specific *** efforts have been made in the literature to increase the specific capacitance of electrode ***,researchers pay more attention on designing supercapacitors of asymmetric type with extending cell voltage and dissimilar materials with complementary working *** try to increase the specific energy of asymmetric supercapacitors(ASCs).Conversely,it is still a challenge to find a suitable operation conditions for ASCs in various designs,especially for the one with battery type *** this review,we describe our recent research works and other reports on the preparation of various nanostructured electrode materials and the performances of both symmetric and asymmetric ***,we demonstrate effects of charge balance on the capacitive performances of ASCs which consist of one electrode material of the battery type and one capacitive *** also demonstrate how to evaluate the charge capacities of both positive and negative electrode materials for this ASC application.

关键词： Transition metal oxides Chemical Synthesis Aqueous electrolyte Super capacitors Asymmetric Design

Upregulation of UBAP2L in Bone Marrow Mesenchymal Stem Cells Promotes Functional Recovery in Rats with Spinal Cord Injury

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Current Medical Science 2018年第6期38卷 1081-1089页

作者： guan-lin LIN Huan WANG Jun DAI Xiao LI ming guan Qing DING Huai-xi WANG Huang FANG Department of Orthopaedics Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Post-translational modifications of cellular proteins with ubiquitin or ubiquitin-like proteins regulate many cellular processes,such as cell proliferation,differentiation,apoptosis, signal transduction,intercellular immune recognition,inflammatory response,stress response,and DNA ***4/UBAP2L is an important member in the family of ubiquitin-like proteins,and its biological function remains *** study aimed to investigate the effect of UBAP2L on spinal cord injury (SCI).At first,rat bone marrow mesenchymal stem cells (BMSCs)were infected with adeno-associated virus to induce over-expression of ***,the infected BMSCs were transplanted into rats suffering from semi-sectioned *** results showed that the over-expression of Nice4 significantly promoted the proliferation and differentiation of BMSCs. In addition,the transplantation of infected BMSCs into the injured area of SCI rats improved the function repair of ***,the immunohistochemical and hematoxylin-eosin staining and RT-PCR results showed that the number of neuronal cells,oligodendrocytes,and astrocytes was significantly increased in the injured area,along with significantly upregulated expression ofcyclin D1 and p38 mitogen-activated protein kinase (MAPK).Meanwhile,the expression of caspase 3 protein was significantly *** conclusion,the over-expression of Nice4 gene can promote the functional recovery in SCI rats by promoting cell proliferation and inhibiting apoptosis. The results of this study indicate an alternative option for the clinical treatment of SCI.

关键词： bone marrow mesenchymal stem cells spinal cord injury ubiquitin-associated protein 2-like apoptosis proliferation

Preparation of Silica-Based Superfi cially Porous Silica and its Application in Enantiomer Separations: a Review

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Journal of Analysis and Testing 2021年第3期5卷 242-257页

作者： Zhongshan Liu Kaijun Quan Hui Li Jia Chen ming guan Hongdeng Qiu College of Chemistry and Chemical Engineering Xinjiang Normal UniversityUrumqi 830054China CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000China College of Chemistry Zhengzhou UniversityZhengzhou 450001China

Chromatographic substrate material,as a carrier of chromatographic stationary phases,plays a vital role in defining its chromatographic characteristics,including column efficiency,stability,peak capacity and so *** recent years,superficially porous silica(SPS)was widely valued for its excellent performance in improving the column efficiency due to its special structural properties,which was considered as a real substitute for fully porous SiO_(2)(FPS)and had been used to develop a new generation of highly efficient stationary *** help researchers better understand the SPS and further promote its application and development in the field of chromatography,the rapid separation mechanism,preparation method and its applications in the rapid separation and analysis of enantiomers were systematically introduced,and the development prospects of SPS were also prospected in this paper.

关键词： Superficially porous SiO2(SPS) Stationary phase Enantiomers separation Chromatographic base

The characteristics of cerebrospinal fluid tumor microenvironment in a patient with leptomeningeal metastases from cancer of unknown primary

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Genes & Diseases 2024年第3期11卷 39-42页

作者： Haoyu Ruan Zhe Wang Xuemei Tang Qiong Zhan Kun Chen Lu Gao ming guan Department of Laboratory Medicine Huashan HospitalFudan UniversityShanghai 200040China Department of Laboratory Medicine The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Department of Physiology Naval Medical UniversityShanghai 200433China Department of Oncology Huashan HospitalFudan UniversityShanghai 200040China

Cancer of unknown primary(CUP)is a rare disease characterized by metastases in which the primary tumor is of unknown *** cerebrospinal fluid(CSF)tumor microenvironment of CUP is still unknown.A Chinese male was diagnosed with leptomeningeal metastases from CUP(CUP-LM)based on the following medical examination results:partial leptomeningeal enhancement by brain magnetic resonance imaging,few malignant cells of diverse morphology in CSF,and no abnormalities or lymphadenopathy by systemic examination.

关键词： metastases cerebrospinal fluid