检索结果-南通市图书馆

Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage

Acta Pharmaceutica Sinica B 2021年第2期11卷 456-475,604页

作者： Dominik Bakalarz Marcin Surmiak Xiaoxiao Yang Dagmara Wójcik Edyta Korbut ZbigniewSliwowski grzegorz ginter grzegorz Buszewicz Tomasz Brzozowski Jakub Cieszkowski Urszula Głowacka Katarzyna Magierowska Zhixiang Pan Binghe Wang Marcin Magierowski Department of Physiology Jagiellonian University Medical CollegeCracow 31-531Poland Department of Forensic Toxicology Institute of Forensic ResearchCracow 31-033Poland Department of Internal Medicine Jagiellonian University Medical CollegeCracow 31-531Poland Department of Chemistry and Center for Diagnostics and Therapeutics Georgia State UniversityAtlantaGA30303USA Department of Forensic Medicine Medical University of LublinLublin 20-093Poland

Metal-based carbon monoxide(CO)-releasing molecules have been shown to exert antiinflammatory and anti-oxidative properties maintaining gastric mucosal *** are interested in further development of metal-free CO-based therapeutics for oral ***,we examine the protective effect of representative CO prodrug,*** rat models of gastric damage induced by necrotic ethanol or aspirin,a representative non-steroidal anti-inflammatory *** effectiveness was assessed by measuring the microscopic/macroscopic gastric damage area and gastric blood flow by laser *** mucosal mRNA and/or protein expressions of HMOX1,HMOX2,nuclear factor erythroid 2-related factor 2,COX1,COX2,iNos,Anxa1 and serum contents of TGFB1,TGFB2,IL1 B,IL2,IL4,IL5,IL6,IL10,IL12,tumor necrosis factorα,interferonγ,and GM-CSF were *** content in gastric mucosa was assessed by gas *** with BW-CO-111(0.1 mg/kg,i.g.)increased gastric mucosal content of CO and reduced gastric lesions area in both models followed by increased *** protective effects of the CO prodrug were supported by changes in expressions of molecular ***,because the pathomechanisms of gastric damage differ between topical administration of ethanol and aspirin,the possible protective and anti-inflammatory mechanisms of BW-CO-111 may be somewhat different in these models.

关键词： Gastroprotection Carbon monoxide Prodrug Anti-inflammation NSAID Ethanol Gastric mucosal damage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The IGCP 491 meeting, “Devonian Vertebrates of the Continental Margins”

引用

Episodes 2005年第4期28卷 292-293页

作者： Vachik Hairapetian Michal ginter Department of Geology Azad University Khorasgan branch Esfahan IRAN Institute of Geology University of Warsaw Warszawa POLAND

The first of two meetings of IGCP 491 project ＂Middle Palaeozoic Vertebrate Biogeography, Palaeogeography and Climate＂ planned for 2005 was held in Yerevan, Armenia, from 22 to 27 May. The major focus of the conferenee was on the neritic to hemipelagic vertebrate faunas of the Middle to Upper Devonian on the northern edge of Gondwana and their relationships to contemporaneous faunas of Laurasia and the rest of Gondwana. It was the third general meeting of the project, alter conferences in Riga, Latvia （2003） and Gramado, Brazil （2004）.

关键词：泥盆纪大陆构造气候变化地质条件

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Shifts in Prey Selection and Growth of Juvenile Pikeperch (<i>Sander lucioperca</i>) over Half a Century in a Changing Lake Võrtsjärv

引用

Open Journal of Applied Sciences 2012年第3期2卷 168-176页

作者： Kai ginter Külli Kangur Andu Kangur Peeter Kangur Marina Haldna Centre for Limnology Estonian University of Life Sciences Tartu Estonia

Analysis of historical and recent data is essential to understand how eutrophication and/or climate change might trigger shifts in the feeding mode of fish and trophic dynamics of shallow lakes. To assess long-term changes in the diet and growth of juvenile pikeperch (Sander lucioperca), the prey selection and growth of pikeperch fry from Lake V?rtsj?rv was investigated in 2007 - 2010 and compared with data from 1920 to 1970. Over the observed period, larger cladocerans have become less frequent in the diet as eutrophication has altered the zooplankton community. Furthermore, climate change has triggered a mismatch between the predator and its prey: the smelt population has collapsed but other fish fries are too large for YOY (young-of-the-year) pikeperch. However, the mean length of fish has decreased mainly due to the postponed diet shift.

关键词： Climate Change Eutrophication YOY Pikeperch Long-Term Changes Diet Shift Stomach Content Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

纵向炉石墨化的控制方法

引用

炭素技术 1989年第3期8卷 17-18页

作者： Józef Gonsior Ewa Cebska Teresa Jeremicz Kazimierz Skoczkowski Piotr Stiebler ginter Czerwicki 时雨

用Castner炉石墨化的电极性质及能量要求取决于温度的增长速率。实际上这一速率受被石墨化电极抗热应力的限制。基于石墨化期间炉芯尺寸的变化推荐出一个炉子功率供给的控制方法。

关键词：石墨化炉控制方法增长速率热应力膨胀仪石油焦单位压力电感传感器延伸率热裂纹

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Reflection Asymmetric Shapes in the Neutron-Rich ^(140,143)Ba Isotopes

引用

Chinese Physics Letters 1997年第8期14卷 569-572页

作者： ZHU Sheng-jiang WANG Mu-ge J.H.Hamilton A.V.Ramayya B.R.S.Babu W.C.Ma LONG Gui-lu DENG Jing-kang ZHU Ling-yan LI Ming T.N.ginter J.Komicki J.D.Cole R.Aryaeinejadv Y.K.Dardenne M.W.Drigert J.O.Rasmussen Yu.Ts.Oganessian M.A.Stoyer S.Y.Chu K.E.Gregorich M.F.Mohar S.G.Prussin I.Y.Lee N.R.Johnson F.K.McGowan Department of Physics Tsinghua UniversityBeijing 100084 Department of Physics Vanderbilt UniversityNashvilleTN 37235U.S.A. Department of Physics Mississippi State UniversityMS 39762U.S.A. daho National Engineering Laboratory Idaho FallsID 83415U.S.A. Lawrence Berkeley Laboratory BerkeleyCA 94720U.S.A. Oak Ridge National Laboratory Oak RidgeTN 37831U.SA.

Level schemes for the neutron-rich ^(140,143)Ba nuclei have been determined by study of promptγ-rays in spontaneous fission of ^(252)*** level pattern and enhanced E1 transitions betweenπ=+andπ=-bands show reflection asymmetric shapes with simplex quantum number s=+1 in ^(140)Ba and s=±i in ^(143)Ba,*** octupole deformation stability with spin variation has been discussed.

关键词： bands transitions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gammasphere上裂变丰中子核核结构若干前沿领域的新进展(Ⅱ:第三和第四部分)(英文)

引用

原子核物理评论 2010年第3期27卷 363-389页

作者：罗亦孝 J.H.Hamilton J.O.Rasmussen A.V.Ramayya C.Goodin A.V.Daniel N.J.Stone 朱胜江 J.K.Hwang 刘少华 C.J.Beyer 李科 H.L.Crowell D.Al mehed S.Frauendorf A.Covello V.Di mitrov 张敬业车兴来姜卓 D.Fong A.Gelberg I.Stefanescu A.Gargano E.F.Jones P.M.Gore I.Y.Lee G.M.Ter-Akopian Yu.Ts.Oganessian M.A.Stoyer R.Donangelo 马文超 J.D.Cole J.Kormicki 张学谦 S.C.Wu J.Gilat T.N.ginter S.J.Asztalos Physics Department Vanderbilt University Nashville TN 37235 USA Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Flerov Laboratory for Nuclear Reactions JINR Dubna Russia Joint Institute for Heavy Ion Research Oak Ridge TN 37831 USA Department of Physics Oxford University Oxford OX1 3PU United Kingdom Department of Physics and Astronomy University of Tennessee Knoxville Tennessee 37996 USA Physics Department Tsinghua University Beijing 100084 China Department of Physics University of Notre Dame Notre Dame IN 46556 USA Institut far Strahlenphysik FZD-Rossendorf Postfach 510119 D-01314 Dresden Germany Dipartimento di Scienze Fisiche Universita di Napoli Federico II and Istituto Nazionale di Fisica Nuclear Complesso Universitario di Monte S. Angelo Via Cintia 80126 Napoli Italy Idaho Accelerator Center Idaho State University Pocatello ID-83209-8263 USA Institut fur Kernphysik Universitat zu Koln 50937 Kdln Germany Department of Chemistry and Biochemistry University of Maryland MD 20742 USA Lawrence Livermore National Laboratory Livermore CA 94550 USA Instituto de Fisica Facultad de Ingenieria C. C. 30 11300 Montevideo Uruguay Mississippi State University Drawer 5167 Mississippi State MS 39762 USA Idaho National Laboratory Bldg. IRCPL MS2114 Idaho Falls ID 83415 USA Department of Physics National Tsing Hua University Hsinchu Taiwan 30013 China National Superconducting Cyclotron Laboratory Michigan State University East Lansing Michigan 48824 USA Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA

使用Gammasphere多探测器系统对252Cf裂变源瞬发γ射线进行γ-γ-γ和γ-γ(θ)符合测量,A～100(Z～40,N>56)丰中子核区关于形状过渡、形状共存和形状突变的深入研究获得了新的进展。奇-Z核的系统研究揭示了从Z=39(Y)同位素的轴对称大... 详细信息

使用Gammasphere多探测器系统对252Cf裂变源瞬发γ射线进行γ-γ-γ和γ-γ(θ)符合测量,A～100(Z～40,N>56)丰中子核区关于形状过渡、形状共存和形状突变的深入研究获得了新的进展。奇-Z核的系统研究揭示了从Z=39(Y)同位素的轴对称大四极形变到Z=43(Tc),44(Ru)和45(Rh)同位素中具有中等四极形变之大三轴形变的过渡。Nb(Z=41)同位素具有过渡核的特征。根据邻近同位素和同中素带交叉信息的系统性及推转壳模型(CSM)计算,Tc和Rh偶-N同位素中观察到的带交叉产生于一对h11/2中子的转动顺排。首次观察到100Nb(Z=41,N=59)的高自旋能级纲图和形变态,从而证实了100Nb中的形状共存,并确认,在Nb同位素链上,基态形状突变发生于N=58(球形)到N=59(大形变);而在Sr(Z=38),Y(Z=39)和Zr(Z=40)各同位素链上,基态形状突变均发生于N=59(球形)到N=60(大形变)。100Nb具有大形变基态,同现有理论预言相矛盾,其大形变的基态及转动带所具有的很大的和不规则的转动惯量具有重要的理论意义。对奇-质子Cs(Z=55)和La(Z=57)丰中子同位素八极激发的详细研究,发现了141,143,144Cs同位素链上电二极矩D0随中子数增加而减小的急剧变化,此前在145,147La中观察到的电二极矩D0的较缓和的减小似乎亦很陡地下延至148La。在Cs和La同位素中观察到的电二极矩D0的急剧下降很可能同偶-质子核146Ba和224Ra中观察到的电二极矩D0的急剧下降相类似,后者已获反射非对称平均场壳修正理论的成功解释。实验证明,141Cs具有很大电二极矩D0。141Cs和142Xe中观测到的很大的电二极矩D0和仅在141Cs中观察到的电二极矩D0的simplex量子数相关性需要进一步的理论研究。根据转动频率比值ω-(I)/ω+(I)的检定,同Xe同位素一样,认定Cs同位素中包括号143Cs的八极激发为八极振动,而在La同位素中存在八极形变。

关键词：形状过渡轴对称形状三轴形变形状突变带交叉奇-质子八极激发 B(E1)/B(E2)比值电二极矩D0 二极矩的下降八极振动 Cs,La同位素

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：