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Congenital Heart Disease 2022年第4期17卷 387-392页

作者： gregory Perens Takegawa Yoshida J.Paul Finn UCLA Mattel Children’s Hospital Children’s Heart CenterLos AngelesCAUSA Diagnostic Cardiovascular Imaging Laboratory Department of Radiology12222 David Geffen School of Medicine at UCLALos AngelesCAUSA

An infant male presented with the rare anatomy consisting of situs solitus,concordant atrioventricular connections to L-looped ventricles,double outlet right ventricle(DORV),and hypoplastic aortic arch.6 months after neonatal aortic arch repair,the morphologic right ventricle function deteriorated,and surgical evaluation was undertaken to determine if either biventricular repair with a systemic morphologic left ventricle or right ventricular exclusion was *** initial echocardiography,magnetic resonance imaging(MRI)was used to create detailed axial and 4-dimensional(4D)images and 3-dimensional(3D)printed *** detailed anatomy of this rare,complex case and its use in pre-surgical planning is presented.

关键词： Magnetic resonance imaging cardiac segments 3D printing

Morphodynamic signatures derived from daily surface elevation dynamics can explain the morphodynamic development of tidal flats

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Water science and Engineering 2023年第1期16卷 14-25页

作者： Tim J.Grandjean Jaco C.de smit Jim van Belzen gregory s.Fivash Jeroen van Dalen Tom Ysebaert Tjeerd J.Bouma Department of Estuarine and Delta systems Royal Netherlands Institute for Sea Research(NIOZ)4401 NT YersekeThe Netherlands Faculty of Geosciences Department of Physical GeographyUtrecht University3508 TC UtrechtThe Netherlands

Understanding the sensitivity of tidal flats to environmental changes is ***,most studies rely on process-based models to systematically explain the morphodynamic evolution of tidal *** this study,we proposed an alternative empirical approach to explore tidal flat dynamics using statistical indices based on long-term time series of daily surface elevation *** elevation dynamic(sED)indices focus on the magnitude and period of surface elevation changes,while morphodynamic signature(MDs)indices relate sediment dynamics to environmental *** statistical analyses were applied to an intervention site in the Netherlands to determine the effect of recently constructed groynes on the tidal *** these analyses,we were able to(1)detect a reduction in the daily sED and(2)determine that the changes in the daily sED were predominantly caused by the reduction in wave impact between the groynes rather than the reduction in tidal ***,the presented results showed that the combination of novel statistical indices provides new insights into the trajectories of tidal flats,ecosystem functioning,and sensitivity to physical drivers(wind and tides).Finally,we suggested how the sED and MDs indices may help to explore the future trajectories and climate resilience of intertidal habitats.

关键词： surface elevation dynamics Tidal flat trajectories Morphodynamic development Morphodynamic signature Bed level dynamics

GrapevineXL reliably predicts multi-annual dynamics of vine water status, berry growth, and sugar accumulation in vineyards

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Horticulture Research 2023年第6期10卷 56-69页

作者： Weiwei Yang Junqi Zhu Cornelis van Leeuwen Zhanwu Dai gregory AGambetta Beijing Key Laboratory of Grape science and Enology and Key Laboratory of Plant Resources Institute of Botanythe Chinese Academy of SciencesBeijing100093China EGFV Univ.BordeauxBordeaux Sciences AgroINRAEISVVVillenave d’Ornon33882France The Key Laboratory of special Fruits and Vegetables Cultivation Physiology and Germplasm Resources Utilization in Xinjiang Production and Construction Group College of AgricultureShihezi UniversityShihezi832000China The New Zealand Institute for Plant&Food Research Limited Blenheim 7201New Zealand China National Botanical Garden Beijing 100093China

Climate and water availability greatly affect each season’s grape yield and *** models to accurately predict environment impacts on fruit productivity and quality is a huge *** calibrated and validated the functional-structural model,GrapevineXL,with a data set including grapevine seasonal midday stem water potential(�xylem),berry dry weight(DW),fresh weight(FW),and sugar concentration per volume([sugar])for a wine grape cultivar(Vitis vinifera *** Franc)in field conditions over 13 years in Bordeaux,*** results showed that the model could make a fair prediction of seasonal�xylem and good-to-excellent predictions of berry DW,FW,[sugar]and leaf gas exchange responses to predawn and midday leaf water potentials under diverse environmental conditions with 14 key *** running virtual experiments to mimic climate change,an advanced veraison(*** onset of ripening)of 14 and 28 days led to significant decreases of berry FW by 2.70%and 3.22%,clear increases of berry[sugar]by 2.90%and 4.29%,and shortened ripening duration in 8 out of 13 simulated years,***,the impact of the advanced veraison varied with seasonal patterns of climate and soil water ***,the results showed that the GrapevineXL model can predict plant water use and berry growth in field conditions and could serve as a valuable tool for designing sustainable vineyard management strategies to cope with climate change.

关键词： sugar cultivar sugar

Rotation and transposition flaps in facial plastic and reconstructive surgery

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Plastic and Aesthetic Research 2022年第1期9卷 466-479页

作者： sebastian sciegienka Andrea Hanick gregory Branham Department of Otolaryngology-Head and Neck surgery Washington University in Saint LouisSt.LouisMO 63110USA Department of Facial Plastic and Reconstructive surgery Otolaryngology-Head and Neck SurgeryWashington University in Saint LouisSt.LouisMO 63110USA

Reconstructive defects of the human face pose unique challenges to even the most experienced surgeon given their myriad of presentations and the individuality of each patient’s anatomy,clinical presentation,and perspective or preferences.A robust armamentarium of reconstructive options must be cultivated for each facial subunit so that experience and artistry can be best utilized to rebuild the patient’s structure and *** review will outline a subset of local rotation and transposition flaps that are most useful for facial reconstruction,organized by facial subunit.

关键词： Rotation transposition reconstruction local flap

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lats基因在细胞周期和肿瘤发生中的作用

生物化学与生物物理进展 2001年第6期28卷 811-814页

作者：陈伟丽邓可京 T.s.gregory 许田上海复旦大学生命科学院发育生物学实验基地上海200433 Howard Hughes Medical Institute Yale UniversitySchool of MedicineDepartment of Genetics

lats基因 (largetumorsuppressorgene)最早在果蝇中发现 ,在小鼠和人中均有同源基因 .该基因的功能从果蝇到人是高度保守的 .lats基因的功能包括 :作为肿瘤抑制基因 ,其突变会导致肿瘤的发生 ;磷酸化的Lats与Cdc2结合 ,参与细胞周期的调... 详细信息

lats基因 (largetumorsuppressorgene)最早在果蝇中发现 ,在小鼠和人中均有同源基因 .该基因的功能从果蝇到人是高度保守的 .lats基因的功能包括 :作为肿瘤抑制基因 ,其突变会导致肿瘤的发生 ;磷酸化的Lats与Cdc2结合 ,参与细胞周期的调控 ;通过细胞细胞间的通讯 ,可能参与生物体个体大小的调控机制 .从果蝇到人lats基因功能的研究。

关键词： lats基因肿瘤抑制基因肿瘤发生细胞周期细胞周期因子大小调控果蝇模式生物

Acute colonic pseudo-obstruction: A systematic review of aetiology and mechanisms

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World Journal of Gastroenterology 2017年第30期23卷 5634-5644页

作者： Cameron I Wells gregory O’Grady Ian P Bissett Department of surgery University of Auckland Department of surgery Auckland District Health Board

To critically review the literature addressing the definition, epidemiology, aetiology and pathophysiology of acute colonic pseudo-obstruction (ACPO). METHODsA systematic search was performed to identify articles investigating the aetiology and pathophysiology of ACPO. A narrative synthesis of the evidence was undertaken. REsULTsNo consistent approach to the definition or reporting of ACPO has been developed, which has led to overlapping investigation with other conditions. A vast array of risk factors has been identified, supporting a multifactorial aetiology. The pathophysiological mechanisms remain unclear, but are likely related to altered autonomic regulation of colonic motility, in the setting of other predisposing factors. CONCLUsIONFuture research should aim to establish a clear and consistent definition of ACPO, and elucidate the pathophysiological mechanisms leading to altered colonic function. An improved understanding of the aetiology of ACPO may facilitate the development of targeted strategies for its prevention and treatment.

关键词： Acute colonic pseudoobstruction Acute colonic pseudo-obstruction Colonic Intestinal Pseudo obstruction Ogilvie’s syndrome Pseudo-Obstruction Pseudo-Obstruction

On a strongly Damped Wave Equation for the Flame Front

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Chinese Annals of Mathematics,series B 2010年第6期31卷 819-840页

作者： Claude-Michel BRAUNER Luca LORENZI gregory I. sIVAsHINsKY Chuanju XU school of Mathematical sciences Xiamen University 361005 Xiamen Fujian China Dipartimento di Matematica Università degli Studi di Parma Viale Parco Area delle Scienze 53/A 43124 Parma Italy school of Mathematical sciences Tel Aviv University 69978 Tel Aviv Israel

In two-dimensional free-interface problems, the front dynamics can be modeled by single parabolic equations such as the Kuramoto-sivashinsky equation (K-s). However, away from the stability threshold, the structure of the front equation may be more involved. In this paper, a generalized K-s equation, a nonlinear wave equation with a strong damping operator, is considered. As a consequence, the associated semigroup turns out to be analytic. Asymptotic convergence to K-s is shown, while numerical results illustrate the dynamics.

关键词： Front dynamics Wave equation Kuramoto-sivashinsky equation stability Analytic semigroups spectral method

Effects of Nitric Oxide Fumigation on Mortality of Light Brown Apple Moth, <i>Epiphyas postvittana</i>(Lepidoptera: Tortricidae)*

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Agricultural sciences 2021年第11期12卷 1286-1294页

作者： Yong-Biao Liu gregory s. simmons UsDA-ARs Salinas CA USA

Light brown apple moth, Epiphyas postvittana, is a quarantine pest in most countries and has established in California and, therefore, has potential to affect export of fresh products from infested areas. There is currently lack of effective treatment especially against eggs. Nitric oxide is a recently discovered fumigant for postharvest pest control and is evaluated in laboratory fumigations to determine its efficacy against different life stages of this pest. small scale fumigations with nitric oxide at 1.0%, 2.0%, 3.0%, and 5.0% concentrations were conducted under ultralow oxygen conditions at 2˚C against larvae, pupae, and eggs of light brown apple moth. Treatment times ranged from 4 to 24 h depending on nitric oxide concentration and life stage. Complete control of larvae and pupae was achieved in 8 h fumigation with 2.0% NO. Eggs were successfully controlled in 6, 12, and 24 h fumigations with 5.0%, 3.0%, and 2.0% NO respectively. The study demonstrated that nitric oxide fumigation was effective against all life stages of light brown apple moth and, therefore, has potential to be an alternative treatment to methyl bromide fumigation for postharvest control of light brown apple moth.

关键词： Quarantine Treatment Nitric Oxide Fumigation Light Brown Apple Moth

Optical tissue clearing enables rapid,precise and comprehensive assessment of three-dimensional morphology in experimental nerve regeneration research

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Neural Regeneration Research 2022年第6期17卷 1348-1356页

作者： simeon C.Daeschler Jennifer Zhang Tessa Gordon gregory H.Borschel sickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Division of Plastic and Reconstructive surgery the Hospital for Sick ChildrenTorontoONCanada Indiana University school of Medicine IndianapolisINUSA

Morphological analyses are key outcome assessments for nerve regeneration studies but are historically limited to tissue *** optical tissue clearing techniques enabling three-dimensional imaging of entire organs at a subcellular resolution have revolutionized morphological studies of the *** extend their applicability to experimental nerve repair studies we adapted these techniques to nerves and their motor and sensory targets in *** solvent-based protocols rendered harvested peripheral nerves and their target organs transparent within 24 hours while preserving tissue architecture and *** optical clearing was compatible with conventional laboratory techniques,including retrograde labeling studies,and computational image segmentation,providing fast and precise cell ***,optically cleared organs enabled three-dimensional morphometry at an unprecedented scale including dermatome-wide innervation studies,tracing of intramuscular nerve branches or mapping of neurovascular *** their wide-ranging applicability,rapid processing times,and low costs,tissue clearing techniques are likely to be a key technology for next-generation nerve repair *** procedures were approved by the Hospital for sick Children’s Laboratory Animal services Committee(49871/9)on November 9,2019.

关键词： histology image segmentation morphometry nerve regeneration outcome assessment peripheral nerve three-dimensional imaging tissue clearing

Holes in Fossil shells show Effects of Competition and Evolution

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当代外语研究 2005年第3期 22-21页

作者： gregory s.Herbert 张永红

化石能够或多或少地反映出当时生物及其生存环境的状况,这为人类了解生命的历史和地球上生态环境变迁的历史提供了重要的线索。一代又一代的科学家通过对不断发现的越来越多的生物化石的研究,根据它们形态特征上的异同来了解各门类生物... 详细信息

化石能够或多或少地反映出当时生物及其生存环境的状况,这为人类了解生命的历史和地球上生态环境变迁的历史提供了重要的线索。一代又一代的科学家通过对不断发现的越来越多的生物化石的研究,根据它们形态特征上的异同来了解各门类生物之间的亲缘关系。

关键词： Holes in Fossil shells show Effects of Competition and Evolution