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Journal of Ancient Civilizations 2013年第1期28卷 144-147页

作者： Juan Pablo sánchez Hernández Institute for the History of Ancient Civilizations Northeast Normal University

Review article:COEDès,*** of Greek and Latin Authors on the Far East:Texts Revised and Translated by John sheldon with Contributions by ***,*** Faha&gregory Fox,(XL+185 p.,4 b/w ill.,160 x ***:978-2-503-53366-7 EUR 65,Paperback)and sHELDON,*** on George Coèdes’Texts of Greek and Latin Authors on the Far East.(XVIII+321 p.,160 x 240 mm,IsBN:*** 65,paperback)studia Antiqua Australiensia 4 and ***:Turnhout.

关键词：加利福尼亚大学书评美国加州图书馆出版社洛杉矶

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Connective tissue growth factor differentially binds to members of the cystine knot superfamily and potentiates platelet-derived growth factor-B signaling in rabbit corneal fibroblast cells

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World Journal of Biological Chemistry 2015年第4期6卷 379-388页

作者： Liya Pi Pei-Yu Chung sriniwas sriram Masmudur M Rahman Wen-Yuan song Edward W scott Bryon E Petersen gregory s schultz Department of Pediatrics University of Florida Johnson and Johnson Vision Care Department of Ophthalmology Schepens Eye Research InstituteHarvard Medical School Department of Molecular Genetics and Microbiology University of Florida Department of Plant Pathology University of Florida Department of Obstetrics and Gynecology University of Florida

AIM:To study the binding of connective tissue growth factor(CTGF) to cystine knot-containing ligands and how this impacts platelet-derived growth factor(PDGF)-B signaling. METHODs:The binding strengths of CTGF to cystine knot-containing growth factors including vascular en-dothelial growth factor(VEGF)-A,PDGF-B,bone morphogenetic protein(BMP)-4,and transforming growth factor(TGF)-β1 were compared using the LexA-based yeast two-hybrid system. EYG48 reporter strain that carried a wild-type LEU2 gene under the control of Lex A operators and a lac Z reporter plasmid(p80plac Z) containing eight high affinity Lex A binding sites were used in the yeast two-hybrid analysis. Interactions between CTGF and the tested growth factors were evaluated based on growth of transformed yeast cells on selective media and colorimetric detection in a liquid β-galactosidase activity assay. Dissociation constants of CTGF to VEGF-A isoform 165 or PDGF-BB homo-dimer were measured in surface plasma resonance(sPR) analysis. CTGF regulation in PDGF-B presentation to the PDGF receptor β(PDGFRβ) was also quantitatively assessed by the sPR analysis. Combinational effects of CTGF protein and PDGF-BB on activation of PDGFRβ and downstream signaling molecules ERK1/2 and AKT were assessed in rabbit corneal fibroblast cells by Western analysis. REsULTs:In the LexA-based yeast two-hybrid system,cystine knot motifs of tested growth factors were fused to the activation domain of the transcriptional factor GAL4 while CTGF was fused to the DNA binding domain of the bacterial repressor protein Lex A. Yeast cotransformants containing corresponding fusion proteins for CTGF and all four tested cystine knot motifs survived on selective medium containing galactose and raffinose but lacking histidine,tryptophan,and uracil. In liquid β-galactosidase assays,CTGF expressing cells that were co-transformed with the cystine knot of VEGF-A had the highest activity,at 29.88 ± 0.91 fold above controls(P s conta

关键词： Connective tissue growth factor Vascular endotheli

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三次注气压力对提高采收率的影响

国外油田工程 1998年第3期14卷 1-9页

作者： R.B.Grigg M.D.gregory J.D.Purkaple 杜劲松皇甫煊刘盼喜钱利中原油田地质调查处

对五个原油样品所作的28次三次注气岩芯驱替试验，确立了其压力／采收率的曲线并与相同样品所做的细管采收率试验进行了比较。油田内s、H和M油藏已经完成或正在进行CO2驱替，F和A油藏考虑分别采用注CO_2和烃气。四个CO2注入系统的结果... 详细信息

对五个原油样品所作的28次三次注气岩芯驱替试验，确立了其压力／采收率的曲线并与相同样品所做的细管采收率试验进行了比较。油田内s、H和M油藏已经完成或正在进行CO2驱替，F和A油藏考虑分别采用注CO_2和烃气。四个CO2注入系统的结果与细管试验非常相似。表明在MMP（最小混溶压力）下，采收率下降显著。烃气注入系统的采收率随压力下降线性递减。与MMP无关。对短岩芯而言，最好使用外部过渡带发生器。目前已成功地发展了一种阻止大多数过渡带发生器中产生原油再饱和的新方法。

关键词：提高采收率三次注气压力原油油田

美国内华达Goldstrike矿区卡林型贝茨金矿同变形的富矿分带(续)

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地质找矿论丛 2000年第2期15卷 115-132页

作者： stephen G.Peters gregory C.Ferdock Maria B.Woitsekhow skaya Robert Leonardson Jerry Rahn 李永明美国地质调查所里诺分部内华达大学马凯矿业学院美国内华达里诺895570047 美国内华达大学马凯矿业学院地质科学系美国内华达里诺895570047 巴利克Goldstrike矿业有限公司矿山地质部美国内华达埃尔科89803 不详

(接第1期第16页) 3 富矿分带与控制因素贝茨金矿中不同矿石矿物组合和蚀变类型的分布与构造背景、围岩岩石及在矿体中的位置有关.根据形态、矿物组成和地质背景可分出几种空间形式截然不同的矿石类型,彼此之间由废石或低含金量的岩石... 详细信息

(接第1期第16页) 3 富矿分带与控制因素贝茨金矿中不同矿石矿物组合和蚀变类型的分布与构造背景、围岩岩石及在矿体中的位置有关.根据形态、矿物组成和地质背景可分出几种空间形式截然不同的矿石类型,彼此之间由废石或低含金量的岩石所分隔.富矿体的地球化学、矿物学、地质及冶金方面的分带在三维空间上是连续的.富矿体的形状和定位与Peters向斜构造的特征,沉积岩的岩石组成以及闪长岩接触带的几何形态和厚度有关(图6A,B).

关键词：卡林型金矿同变形富矿分带美国金矿床

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三次注气压力对提高采收率的影响

石油石化节能与计量 1998年第3期 1-9页

作者： R.B.Grigg,M.D.gregory,J.D.Purkaple,杜劲松,皇甫煊,刘盼喜,钱利中原油田地质调查处中原油田地质调查处中原油田地质调查处中原油田地质调查处

对五个原油样品所作的28次三次注气岩芯驱替试验，确立了其压力／采收率的曲线并与相同样品所做的细管采收率试验进行了比较。油田内s、H和M油藏已经完成或正在进行CO2驱替，F和A油藏考虑分别采用注CO2和烃气。四个CO2注入系统的结果与... 详细信息

对五个原油样品所作的28次三次注气岩芯驱替试验，确立了其压力／采收率的曲线并与相同样品所做的细管采收率试验进行了比较。油田内s、H和M油藏已经完成或正在进行CO2驱替，F和A油藏考虑分别采用注CO2和烃气。四个CO2注入系统的结果与细管试验非常相似。表明在MMP（最小混溶压力）下，采收率下降显著。烃气注入系统的采收率随压力下降线性递减。与MMP无关。对短岩芯而言，最好使用外部过渡带发生器。目前已成功地发展了一种阻止大多数过渡带发生器中产生原油再饱和的新方法。

关键词：岩芯气驱最小混溶压力三次驱替饱和度细管试验采收率

γ-secretase binding sites in aged and Alzheimer's disease human cerebrum:The choroid plexus as a putative origin of CsF Aβ

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γ-Secretase binding sites in aged and Alzheimer's disease h...

中国神经科学学会第十届全国学术会议

作者： Zhi-Qin XUE Fei LIU si-Hao DENG Xiong KUN Xue-Gang LUO Peter R.Patrylo gregory M.Rose Huai-Bin CAI Robert G.struble Yan CAI Xiao-Xin YAN Department of Anatomy and Neurobiology Central South University Xiangya School of Medicine Department of Anatomy Xinjiang Medical University Department of Neurosurgery The Third Xiangya HospitalCentral South University Center for Integrated Research in Cognitive and Neural sciences Southern Illinois University Carbondale Laboratory of Neurogenetics National Institute on AgingNational Institutes of Health

Deposition of β-amyloid(Aβ) peptides,cleavage products of p-amyloid precursor protein(APP) by p-secretase-1(BACE1) and y-secretase,is a neuropathological hallmark of Alzheimer’s disease(AD).γ-secretase inhibition is a therapeutical anti-Aβ approach,although less is clear about the change of the enzyme’s activity in AD *** fluid(CsF) Aβ peptides are considered to derive from brain parenchyma,thus may serve as biomarkers for assessing cerebral amyloidosis and anti-Ap *** present study compared active y-secretase binding sites with Ap deposition in aged and AD human cerebrum,and explored a possibility of Ap production and secretion by the choroid plexus(CP).specific binding density of[H]-L-685,458,a radiolabeled high affinity y-secretase inhibitor,in the temporal neocortex and hippocampal formation was similar for AD and control cases with comparable ages and postmortem *** CP in postmortem samples exhibited exceptionally high[H]-L-685,458binding density,with the estimated maximal binding sites(Bmax) reduced in the AD relative to control *** resected human CP exhibited APP,BACE1 and presenilin-1 immunoreactivity,and p-site APP cleavage enzymatic *** primary culture,human CP cells also expressed these amyloidogenic proteins but released Ap40and Ap42 into the *** results suggest that y-secretase activity appears not altered in the cerebrum in AD related to aged control,nor correlated with regional amyloid plaque *** choroid plexus appears to represent a novel non-neuronal source in the brain that may contribute Ap into cerebrospinal fluid,probably at reduced levels in AD.

关键词： β-amyloid BACE1 γ-secretase anti-Aβ therapy AD biomarker

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阿根廷大豆的国际价格传导动态研究

阿根廷大豆的国际价格传导动态研究

作者： Guillermo Andrés Larre 中国农业科学院

学位级别：硕士

从1999年至2019年间,阿根廷大豆出口价格经历了几次大幅波动,受到高度关注。本研究侧重分析了阿根廷大豆出口价格变动与其他大豆主要出口国市场价格之间的传导关系。出口大豆主要来源于阿根廷、巴西和美国,因此选取这三个国家月度离岸... 详细信息

从1999年至2019年间,阿根廷大豆出口价格经历了几次大幅波动,受到高度关注。本研究侧重分析了阿根廷大豆出口价格变动与其他大豆主要出口国市场价格之间的传导关系。出口大豆主要来源于阿根廷、巴西和美国,因此选取这三个国家月度离岸价格分析价格间的横向传导机制。首先采用gregory-Hansen带结构断点的协整检验分析三者间的协整关系,其次通过VECM向量误差修正模型反映偏离长期均衡状态的短期修正机制,为了排除个别大幅波动价格带来的影响,将样本区间按照时间节点再次划分为3个子样本,在此基础上,分别对子样本运用Toda-Yamamoto方法进行价格间Granger因果关系检验。研究发现:阿根廷、美国与巴西出口大豆价格间存在带结构断点的协整关系,断点发生在2009年7月,同时因果关系显示,最初美国大豆出口价格是阿根廷和巴西出口价格波动的Granger原因,但从2007年开始,阿根廷出口价格同时也是美国和巴西价格波动的Granger原因。结果表明,对美国和巴西大豆出口未来价格预测时需要考虑阿根廷大豆出口价格波动的影响。此外,本研究也验证了一价定律在国际商品市场上的适用性。

关键词：国际大豆价格横向空间传导协整分析 Granger因果关系结构突变

Coarctation of the aorta:Management from infancy to adulthood

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World Journal of Cardiology 2015年第11期7卷 765-775页

作者： Rachel D Torok Michael J Campbell gregory A Fleming Kevin D Hill Division of Pediatric Cardiology Department of PediatricsDuke University Medical Center

Coarctation of the aorta is a relatively common form of congenital heart disease, with an estimated incidence of approximately 3 cases per 10000 births. Coarctation is a heterogeneous lesion which may present across all age ranges, with varying clinical symptoms, in isolation, or in association with other cardiac defects. The first surgical repair of aortic coarctation was described in 1944, and since that time, several other surgical techniques have been developed and modified. Additionally, transcatheter balloon angioplasty and endovascular stent placement offer less invasive approaches for the treatment of coarctation of the aorta for some patients. While overall morbidity and mortality rates are low for patients undergoing intervention for coarctation, both surgical and transcatheter interventions are not free from adverse outcomes. Therefore, patients must be followed closely over their lifetime for complications such as recoarctation, aortic aneurysm, persistent hypertension, and changes in any associated cardiac defects. Considerable effort has been expended investigating the utility and outcomes of various treatment approaches for aortic coarctation, which are heavily influenced by a patient's anatomy, size, age, and clinical course. Here we review indications for intervention, describe and compare surgical and transcatheter techniques for management of coarctation, and explore the associated outcomes in both children and adults.

关键词： Coarctation of the aorta Cardiac surgery Cardiac c

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运输装卸和模塑纤维与发泡聚苯乙烯苹果托盘

绿色包装 2018年第12期 73-73页

作者： gregory s.Batt Mackenzie Lussier Kay Cooksey Julie Northcutt 不详

华盛顿州的苹果被运往全美各地进行零售,需要足够的包装,以尽量减少苹果在分销过程中的损害。苹果托盘常用的两种材料是膨胀聚苯乙烯(EPs)和成型纤维(MF)。最近,行业从MF转向EPs托盘,引发了人们对探索两者之间业绩差异的兴趣。分布环境... 详细信息

华盛顿州的苹果被运往全美各地进行零售,需要足够的包装,以尽量减少苹果在分销过程中的损害。苹果托盘常用的两种材料是膨胀聚苯乙烯(EPs)和成型纤维(MF)。最近,行业从MF转向EPs托盘,引发了人们对探索两者之间业绩差异的兴趣。分布环境危害包括冲击、振动和压缩力。以往的研究主要集中在比较EPs和MF托盘在苹果保护中的振动或冲击性能。在本研究中,我们在一个更大的抽样范围内考虑了案例包装和零售制剂之间所遇到的各种典型危害。对冲击、振动和层间动力压缩力进行了模拟,并对人工处理情况下可能出现的自由落体进行了模拟。摘要提出了一种新的装置和试验方法来模拟人手从苹果盒中取出苹果托盘所产生的力量。并对苹果冷凝最严重的情况进行微生物分析,比较托盘材料对苹果微生物种群的影响。通过物理和微生物检测,得出EPs和MF苹果托盘在物理保护和微生物种群增长方面没有统计学差异。苹果托盘材料的选择可以转移到其他因素,如成本或消费者的喜好。

关键词： MF 微生物种群

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