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ACTN3 and AMPD1 Polymorphism and Genotype Combinations in Bulgarian Athletes Performing Wingate Test

Journal of Sports Science 2015年第1期3卷 1-10页

作者： Peter Atanasov Trayana Djarova Michael Kalinski Lubomir Petrov Radka Kaneva Sam Mugandani gregori watson Monem Jemni Department of Theory and Methods of Physical Education Faculty of Pedagogy Paissii Hilendarski Plovdiv University Plovdiv4000 Bulgaria Department of Biochemistry and Microbiology University of Zululand Private Bag XI O01 KwaDlagenzwa 3886 South Africa Department of Applied Health Sciences Murray State University Murray Kentucky 42071-3347 USA Department of Physiology and Biochemistry National Sports Academy Sofia 1700 Bulgaria Molecular Medicine Centre Medical Academy Sofia 1431 Bulgaria Department of Biokinetics and Sport Science University of Zululand KwaDlangezwa 3886 South Africa Department of Rehabilitation and Health Sciences Leeds Metropolitan University Leeds LS1 3HE United Kingdom Department of Sport Science College of Arts and Sciences Qatar University AI Tarfa Doha 2713 Qatar

The aim of the study was to investigate ACTN3 （ct-actinin-3） and AMPD1 （adenosine monophosphate deaminase） polymorphism and genotype combinations in Bulgarian athletes competing in various sports and the relation to peak power output. A mixed group of athletes （n = 52） competing at national and international level and a matching genetic control group （n = 109） of volunteers were recruited. Participants were genotyped for ACTN3 and AMPD1 by polymerase chain reaction. There were no significant differences in ACTN3 genotype distribution between athletes performing Wingate test （38% RR, 46% RX, 16% XX） and controls （41.2% RR, 46% RX, 12.8% XX）. AMPD1 distribution was （73% CC, 27% CT, 0% TT） and in controls （73.2% CC, 25% CT, 1.8% TT）. Athletes performing Wingate test showed equal 33% frequency of RR/CC and RX/CC combination, and 12% RX/CT. Significantly higher （P 〈 0.05） peak power output （11.10 W kg1） was found in athletes with RX/CT combination compared to other combinations （range： 8.83-9.71 W kg-1） and in R-power （RR ＋ RX） and C-power （CC ＋ CT） dominant models （9.91 W kgl）. Mean power was higher （P 〈 0.05） in RX/CT combination （8.93 W kg-1） compared to RR/CC （7.75 W kg-1） and RR/CT （7.95 W kgl）. In conclusion, the low frequency of T AMPD1 allele in Bulgarian athletes might indicate that this mutant allele is related to the physical performance. The prevalence of R ACTN3 and C AMPD1 alleles suggests that they could contribute to anaerobic performance. Higher peak power in Wingate test is associated with RX/CT genotype combination and R- and C-power dominant models.

关键词： Genetics, metabolism, exercise, performance, peak power.

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Early Permian arc-related volcanism and sedimentation at the western margin of Gondwana： Insight from the Choiyoi Group lower section

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Geoscience Frontiers 2016年第5期7卷 715-731页

作者： Leonardo Strazzere Daniel A.gregori Leonardo Benedini CONICET and Catedra de Ceologia Argentina Departamento de Geologia Universidad Nacional del Sur San Juan 670 8000 Bahia Blanca Argentina

Permian sedimentary and basic to intermediate volcanic rocks assigned to the Conglomerado del Río Blanco and Portezuelo del Cenizo Formation, lower part of the Choiyoi Group, crop out between the Cordon del Plata, Cordillera Frontal and Precordillera of Mendoza Province, Argentina. The sedimentary rocks are represented by six lithofacies grouped in three facies associations. They were deposited by mantled and gravitational flows modified by high-energy fluvial currents that evolved to low-energy fluvial and lacustrine environments. They constitute the Conglomerado del Río Blanco, which cover unconformably marine Carboniferous sequences. Five volcanic and volcaniclastic facies make up the beginning of volcanic activity. The first volcanic event in the Portezuelo del Cenizo is basaltic to andesitic lava-flows emplaced in the flanks of volcanoes. Lava collapse produced thick block and ash *** in the intermediate volcanic rocks, there are dacites of different geochemical signature,which indicate that the development of acidic volcanism was coetaneous with the first volcanic *** geochemistry of these rocks induces to consider that the Choiyoi Group Lower section belongs to a magmatic arc on continental crust. The age of this section is assigned to the lower Permian（277 ？ 3.0Ma, Kungurian age）.

关键词： Choiyoi group lower section Conglomerado del Río Blanco Cordillera Frontal Argentina

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Seismic hazard analysis for central-western Argentina

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Geodesy and Geodynamics 2018年第1期9卷 25-33页

作者： Salvador Daniel gregori Rodolfo Christiansen Instituto Geofísico Sismológico Volponi Nacional de San Juan(National University of San Juan)San JuanArgentina CONICET(National Scientific and Technical Research Council) San JuanArgentina

In this study, we present a PSHA（Probabilistic Seismic Hazard Analysis） for the city of San Juan, which is located in the central-western region of Argentina（30°S-35.5°S; 66.5°W-71°W）. In addition to crustal earthquakes provided by catalogues, recent paleoseismological and neotectonic investigations have permitted to consider events which occurred during the last 400 *** seismogenic sources that could cause damages to the studied site corresponding to Precordillera,Western Sierras Pampeanas, Basement of the Cuyana Basin and Cordillera Principal were *** on the evaluation of the contribution of these sources,maximum moment magnitudes above 7.5（Mw） are *** values of SA（spectral acceleration）（0.2 and 1 s periods） and PGA（peak ground acceleration） were found in the city of San Juan, which suggests that it is located in a zone of high seismic ***, the obtained SA spectra were compared with the seismic-resistant construction standards of Argentina INPRES-CIRSOC 103 [1]. Results suggest that for the city of San Juan and for a return period of475 years, it covers the seismic requirements of the structures.

关键词： Probabilistic seismic hazard analysis Seismic-resistant construction standards Seismic sources Visual cumulative method

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Lingual mucosal graft urethroplasty 12 years later: Systematic review and meta-analysis

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Asian Journal of Urology 2019年第3期6卷 230-241页

作者： Alberto Abrate Andrea gregori Alchiede Simonato Department of Surgical Oncological and Oral SciencesSection of UrologyUniversity of PalermoPalermoItaly Department of Urology ASST RhodenseG.Salvini HospitalGarbagnate MilaneseMilanItaly

Objective:To evaluate the functional results and complications of the lingual mucosal graft(LMG)urethroplasty and to sum up the current state of the art of this surgical ***:A systematic search of PubMed and Scopus electronic databases was performed,according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)*** involving male patients treated with LMG urethroplasty for urethral stricture were *** protocol is available at http://***/PROSPERO/display_***?ID=CRD42017080121.A meta-analysis comparing functional and long-term oral complication outcomes of LMG and buccal mucosal graft(BMG)was performed,calculating the odds ratio(OR)and 95%confidence interval(CI).Results:Twenty original articles were included in the qualitative *** of 1.5e16.5 cm have been treated with LMG urethroplasty,due to the improvement of harvesting technique and very low rate of long-term oral *** good functional results have been reported by different authors for LMG urethroplasty,with lower rate of oral complications than *** meta-analysis included six comparative studies involving 187 and 178 patients treated with LMG and BMG urethroplasty,*** OR of 1.65(95%CI[0.95e2.87],I^2=0%)and 0.18(95%CI[0.03e1.26],I^2=68%)were found for LMG *** urethroplasty,in terms of success and oral complication rate,***:LMG urethroplasty can be reasonably considered a first choice technique for urethral stricture with very good *** complications are temporary and minimally disabling,basically less than those for BMG,and depend mainly on the graft extent.

关键词： Lingual mucosal graft Meta-analysis Systematic review Urethral stricture Urethroplasty

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The Gondwana Orogeny in northern North Patagonian Massif:Evidences from the Caita Có granite, La Se?a and Pangaré mylonites,Argentina

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Geoscience Frontiers 2016年第4期7卷 621-638页

作者： Daniel A.gregori Bernhardt Saini-Eidukat Leonardo Benedini Leonardo Strazzere Mercedes Barros José Kostadinoff Cátedra de Geología Argentina Departamento de Geología Universidad Nacional del Sur and INGEOSUR Department of Geosciences North Dakota State University Cátedra de Campos Gravitacionales Departamento de Física Universidad Nacional del Sur

Structural analyses in the northern part of the North Patagonia Massif, in the foliated Caita Co granite and in La Sefia and Pangare mylonites, indicate that the pluton was intruded as a sheet-like body into an opening pull-apart structure during the Gondwana Orogeny. Geochronological studies in the massif indicate a first, lower to middle Permian stage of regional deformation, related to movements during indentation tectonics, with emplacement of foliated granites in the western and central areas of the North Patagonian Massif. Between the upper Permian and lower Triassic, evidence indicates emplacement of undeformed granitic bodies in the central part of the North Patagonian Massif. A second pulse of deformation between the middle and upper Triassic is related to the emplacement of the Caita CO granite, the development of mylonitic belts, and the opening of the Los Menucos Basin. During this pulse of deformation, compression direction was from the eastern quadrant.

关键词： Gondwana Orogeny Northern Patagonia Foliated granite Mylonites Argentina

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Pennsylvanian glacimarine sedimentation in the Cushamen Formation,western North Patagonian Massif

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Geoscience Frontiers 2018年第2期9卷 485-504页

作者： Paulo Marcos Daniel A.gregori Leonardo Benedini Mercedes Barros Leonardo Strazzere Cecilia Pavón Pivetta Cátedra de Geofísica Departamento de GeologíaUniversidad Nacional del Sur and INGEOSURSan Juan 6708000 Bahía BlancaArgentina Cátedra de Geología Argentina Departamento de GeologíaUniversidad Nacional del Sur and INGEOSURSan Juan 6708000 Bahía BlancaArgentina Cátedra de Geología Minera Departamento de GeologíaUniversidad Nacional del Sur and INGEOSURSan Juan 6708000 Bahía BlancaArgentina

The metasedimentary sequence of the Cushamen Formation in the western North Patagonian Massif is540 m thick and comprises six sedimentary lithofacies associations related to a glacimarine *** of these lithofacies represent distal glacimarine environments, whereas another one was deposited in proximal glacimarine environments, and the last includes subglacial environments. The organization and configuration of these lithofacies associations represent the advance and retreat of the glacier masses. The maximum glacial advance is correlatable with the G2 glacial interval of the Pennsylvanian Pampa de Tepuel, Las Salinas and Valley Chico, formations of the Extraandean Chubut, and the southern part of Neuquen Cordillera. Contemporaneously, in southern Chile there are marine and glacimarine sediments. The chronostratigraphic relationships between the Silurian to Permian units allow five paleogeographic stages to be distinguished. The middle Silurian-late Devonian igneous rocks represent the first magmatic stage. The second stage, which is transitional to the first, is represented by a marine basin that includes the late Devonian-early Carboniferous Esquel and Rio Pescado formations and the Llanquihue Complex. The third stage(early-late Carboniferous) includes granitoids of the second magmatic event that partially overlapped the first magmatic igneous belt. The fourth stage belongs to the late Carboniferous sedimentation of the Cushamen and equivalent formations. The extended early Permian magmatism was the last Paleozoic event in the studied area.

关键词： Pennsylvanian Glacimarine sedimentation Cushamen Formation North Patagonian Massif

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Planktonic ciliate trait structure variation over Yap,Mariana,and Caroline seamounts in the tropical Western Pacific Ocean

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Journal of Oceanology and Limnology 2021年第5期39卷 1705-1717页

作者： Chaofeng WANG Haibo LI Yi DONG Li ZHAO Gérald gregori Yuan ZHAO Wuchang ZHANG Tian XIAO CAS Key Laboratory of Marine Ecology and Environmental Sciences Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laboratory for Marine Ecology and Environmental Science Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China Center for Ocean Mega-Science Chinese Academy of SciencesQingdao 266071China Aix-Marseille University Toulon UniversityCNRSIRDMediterranean Institute of Oceanology UM110Marseille 13288France

Trait structure is increasingly used in plankton ecology to understand diversity and ***,our knowledge of micro zooplankton(*** ciliates)trait structure and its variation with hydrography is *** this study,we analyzed planktonic ciliate trait structure in waters with different hydrography and deep Chlorophyll a maximum(DCM)layers over three seamounts:Yap,Mariana,and Caroline *** seamount had a lower surface temperature than the Yap and Caroline *** layers over Mariana and Caroline seamounts were deeper than Yap *** was a weak upwelling in upper 50 m around top of Mariana *** ciliate distribution showed bimodal pattern(high abundance appeared in the surface and DCM layers)over three *** surface layer,the large size-fraction(>30μm)abundance proportion to aloricate ciliate over Yap seamount(44.4%)was higher than Mariana(32.8%)and Caroline(36.1%)*** tintinnid abundance proportion to total ciliate,Mariana(12.0%)and Caroline(11.5%)seamounts at about 100-m depth were higher than that of Yap seamount(6.4%).Vertically,tintinnid could be divided into 4 groups over the three ***30-m depth,group I(species occurring from surface to 100 m only)was dominant component over Yap and Caroline seamounts,while group IV(species occurring at every depth)changed into dominant component over Mariana seamount,the weak upwelling might be the *** faurei was the top dominant species,which corresponded to deeper DCM layers over Mariana and Caroline *** results showed that the upwelling and the deeper DCM could influence the planktonic ciliate trait structure.

关键词： planktonic ciliate upwelling seamount vertical distribution Western Pacific Ocean

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Cost-effectiveness analysis of beta-blockers vs endoscopic surveillance in patients with cirrhosis and small varices

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World Journal of Gastroenterology 2014年第30期20卷 10464-10469页

作者： Lorenza Di Pascoli Alessra Buja Massimo Bolognesi Sara Montagnese Angelo Gatta Dario gregori Carlo Merkel Hepatic Hemodynamic Laboratory and Clinica Medica 5 Department of MedicineUniversity of Padua35128 PadovaItaly Laboratory of Epidemiological Methodology and Biostatistics Department of Environmental Medicine and Public HealthUniversity of Padua35128 PadovaItaly

AIM: To evaluate the most cost-effectiveness strategy for preventing variceal growth and bleeding in patients with cirrhosis and small esophageal varices.

关键词： Pharmaco-economical analysis Cirrhosis Esophageal varices Variceal bleeding Primary prophylaxis

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Timber-concrete composite bridges:Three case studies

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Journal of Traffic and Transportation Engineering(English Edition) 2018年第6期5卷 429-438页

作者： Massimo Fragiacomo Amedeo gregori Junqing Xue Cristoforo Demartino Matteo Toso Department of Civil Construction-Architectural and Environmental F.ngineeringUniversity of L'AquilaL'Aquila 67200Italy College of Civil Engineering Fuzhou UniversityFuzhou 350108China College of Civil Engineering Nanfling Tech UniversityNanjing 210800China Maffeis Engineering Solagna 36020Italy

During the last years, timber-concrete composite(TCC) structures have been extensively used in Europe both in new and existing buildings. Generally speaking, a composite structure combines the advantages of both materials employed: the strength and stiffness of the concrete in compression and the tensile strength, lightweight, low embodied energy, and aesthetical appearance of the timber. The concrete slab provides protection of the timber beams from direct contact with water, which is crucial to ensure the durability of the timber beams, particularly when used for bridges. Different types of connectors can be used to provide force exchange between the concrete slab and the timber beam. The choice of a structurally effective yet cheap shear connection between the concrete topping and the timber joist is crucial to make the TCC structures a viable solution that can compete with reinforced concrete and steel structures. In this paper, the possibilities offered by TCC structures for short-span bridge decks are discussed. The technology of TCC structures and the general design rules are illustrated. Three case studies are reported, including a short-span bridge tested in Colorado, USA, with the timber layer being constructed from recycled utility poles and notch connection; a TCC bridge with glulam beams and triangular notches with epoxyglued rebar connectors built in Portugal; and a TCC bridge with glulam beams and rectangular notches built in Germany. All the solutions were found to be structurally effective and aesthetically pleasing. They can all provide a sustainable option for short-span bridges.

关键词： Timber-concrete composite Bridge Design Connection system

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Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

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Journal of Innovative Optical Health Sciences 2018年第1期11卷 123-137页

作者： Inmaculada Bueno-Gimeno Enrique España-gregori Andres Gene-Sampedro Juan Carlos Ondategui-Parra Carlos J.Zapata-Rodriguez Department of Optics and Optometry and Vision Science University of Valencia Spain Department of Surgery University of Valencia University Hospital La FeSpain Faculty of Optics and Optometry University Vision Centre Polytechnic University of CataloniaSpain

Purpose:The aim of this paper was to examine the distribution of macular,retinal nerve fiber layer(RNFL)thickness and optic disc parameters of myopic and hyperopic eyes in comparison withemmetropic control eyes and to investigate their variation according to axial length(AL)andspherical equivalent(SE)in healthy ***:This study included 293 pairs of eyes of 293children(145 boys and 148 girks),ranging in age from 6 to 17 years,Subjects were dividedaccording to SE in control(emmetropia,99 children),myopia(100 children)and hyperopia(94children)groups and according to axial AL in 68 short(25.00 mm,36).Macular parameters,RNFL thickness and opticdisc morphology were assessed by the Cirrus^(TM) *** was measured using the ***'s formula was used for calculating the corrected AL-related ocular *** Mean age(±SD)was 10.84±3.05 years;mean(±SD)SE was+0.14±0.51 D(range from8.75 to+8.25 D)and mean AL(±SD)was 23.12±*** RNFL thickness,averagemacular thickness and macular volume decreased as AL and myopia *** correlationsbetween AL/SE and optic disc parameters were found after correcting for magnification ***:AL and refractive error affect measurements of macular and RNFL thickness inhealthy *** make a correct interpretation of ocT measurements,ocular magnificationeffect should be taken into account by clinicians or OCT manufacturers.

关键词： Axial length refractive error children OCT measurements magnification fect

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