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perceived ill-health and health seeking behavior in two communities in the nam theun 2 hydroelectric project area in Lao peoples Democratic Republic

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Asian pacific Journal of Tropical Medicine 2009年第6期2卷 63-70页

作者： Sayasone S Erlanger TE Kaul S Sananikhom p Tanner M Utzinger J Odermatt p Department of public health and Epidemiology Swiss Tropical InstituteBaselSwitzerland Institut de la Francophonie pour la Medecine Tropicale VientianeLao PDR International SOS Singapore Nam Theun 2 Power CompanyVientianeLao PDR Nam Theun 2 power Company VientianeLao PDR

Objective:To compare perceived ill-health and health seeking behavior between two communities affected by the large Nam Theun 2 hydroelectric project in central Lao people’s Democratic Republic(pDR).Methods: Two different affected areas;Nakai plateaubeing remote,sparcely populated and mountainous,and Xe Bang Fai lowland plains,more densely populated and comparatively affluent were *** were obtained from two cross-sectional household-based health and socio-economic ***:We found pronounced differences in the frequency of self-reported fever,cough,headache and myalgia according to *** the Nakai plateau,45.1%of the individuals with ill-health report(recall period;2 weeks) went to a local health volunteer compared to only 7.2%in the Xe Bang Fai area(p here were disproportionately more illiterates seeking help from local health volunteers when compared to those who attended at least primary schooling(49.2%versus 17.5%,p h antimalarials was more common in Xe Bang Fai than on Nakai(32.3%versus 7.0%,p he mean amount of money spent per health consultation was US $ 1.7 in Nakai and US $ 7.2 in Xe Bang ***:The observed differences in self-reported ill-health and health seeking behavior among these two Lao communities need to be considered when implementing setting-specific mitigation measures as part of the public health action plan of the Nam Theun 2 hydroelectric project.

关键词： Self-reported ill-health health seeking behavior Lao pDR Nam Theun 2 hydroelectric project

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An investigation into the vibration of harmonic drive systems

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Frontiers of Mechanical Engineering 2013年第4期8卷 409-419页

作者： M.Masoumi h.Alimohammadi School of Mechanical Engineering Semnan University School of Engineering Tarbiat Modares University

harmonic drive systems are precise and specific transmission gear systems which are beneficial in terms of the high transmission ratio and almost zero *** inherent and spectacular properties result in using this mechanism in robotic and space sciences where the precision and lightwieght play an important *** paper presents a vibration analysis of harmonic drive systems using the shell *** of vibration for the flexspline and the circular spline of the system are derived and used to find the natural frequencies for both parts and,moreover,vibration response of the system under the operating condition is ***,obtained vibration equations are utilized to study the effects of different involved parameters such as the geometry of the flexspline and its gear tooth,eccentricity,and unbalancing on the vibrational behavior of the system.

关键词： harmonic drive system strain wave gearing mechanism vibration analysis natural frequencies

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Spatiotemporal switching signals for cancer stem cell activation in pediatric origins of adulthood cancer:Towards a watch-and-wait lifetime strategy for cancer treatment

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World Journal of Stem Cells 2018年第2期10卷 15-22页

作者： Shengwen Calvin Li Mustafa h Kabeer Neuro-oncology and Stem Cell Research Laboratory Children's Hospital of Orange County Department of Neurology University of California-Irvine School of Medicine Children's hospital of Orange County Department of Surgery University of California-Irvine School of Medicine

pediatric origin of cancer stem cell hypothesis holds great promise and potential in adult cancer treatment, however; the road to innovation is full of obstacles as there are plenty of questions left unanswered. First, the key question is to characterize the nature of such stem cells (concept). Second, the quantitative imaging of pediatric stem cells should be implemented(technology). Conceptually, pediatric stem cell origins of adult cancer are based on the notion that plasticity in early life developmental programming evolves local environments to cancer. Technologically, such imaging in children is lacking as all imaging is designed for adult patients. We postulate that the need for quantitative imaging to measure space-time changes of plasticity in early life developmental programming in children may trigger research and development of the imaging technology. Such quantitative imaging of pediatric origin of adulthood cancer will help develop a spatiotemporal monitoring system to determine cancer initiation and progression. Clinical validation of such speculative hypothesis-that cancer originates in a pediatric environment-will help implement a wait-andwatch strategy for cancer treatment.

关键词： pediatric origins of adult cancer Imaging of single cells

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克苏鲁神话

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作者： (美) h.p.洛夫克拉夫特

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Feasibility of robotic assisted bladder sparing pelvic exenteration for locally advanced rectal cancer:A single institution case series

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World Journal of Gastrointestinal Surgery 2020年第4期12卷 190-196页

作者： Nathaniel h heah Kar Yong Wong Department of Urology Tan Tock Seng HospitalSingapore 308433Singapore Department of General Surgery Tan Tock Seng HospitalSingapore 308433Singapore

BACKGROUND pelvic exenteration for locally advanced rectal cancer involving prostate has been performed via open *** pelvic exenteration offers benefits of better pelvic visualisation and dissection for bladder preserving prostatectomy with vesicourethral anastomosis,while achieving clear *** To determine the feasibility of robotic assisted bladder sparing pelvic *** We describe robotic assisted pelvic exenteration in three cases of locally advanced rectal cancer involving prostate and seminal vesicles(SV).The da Vinci S robotic system was *** console was docked at left oblique position for abdominal phase and redocked to between the patient’s legs for pelvic *** three cases were performed fully robotically at Tan Tock Seng hospital by colorectal and urological *** Case 1:67-year-old with low rectal tumour 3 cm from anal verge involving the *** underwent neo-adjuvant chemoradiotherapy and robotic abdominoperineal resection with en-bloc *** 2:66-year-old with low rectal tumour 3 cm from anal verge involving prostate and bilateral *** underwent neo-adjuvant chemoradiotherapy and robot assisted ultra-low anterior resection with coloanal anastomosis and en-bloc *** 3:57-year-old with metachronous rectal tumour in the rectovesical pouch inseparable from the anterior mid rectum,prostate and bilateral *** underwent robot assisted ultra-low anterior resection with en-bloc *** neck margin revealed cauterized tumour cells,and he underwent total cystectomy and ileal conduit *** revealed no residual *** patients are currently disease free CONCLUSION Robot assisted bladder sparing pelvic exenteration can be safely performed in locally advanced rectal cancer with acceptable surgical outcome while preserving benefits of minimally invasive surgery.

关键词： Rectal cancer Robot surgery pelvic exenteration Anterior resection prostatectomy Minimal invasive surgery

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Integrated Debris Flow Disaster Mitigation—A Comprehensive Method for Debris Flow Disaster Mitigation

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Journal of Mountain Science 2007年第4期4卷 293-308页

作者： h. Wolfgang Weinmeister University of Natural Resources and Applied Life Sciences Vienna Institute of Mountain Risk Engineering (IAN) Gentzgasse 10/6/7 A-1180 Vienna Austria

Integrated disaster mitigation needs interpreting torrent catchment areas as complex landscape systems. The history of valley-evolution shows the influence of climate and vegetation on the valley-evolution. The energy-concept (energy dissipation concept including the idea of the energy-line) is used for a simple explanation of debris flow. Examples of heavy debris flow disasters in controlled torrents in the Alps and pyrenees give hints, which expanding the time scale can show that side-effects restrict or counteract the mitigation measures. A pallet of different mitigation measures to avoid or to reduce some of the side-effects is shown. The comprehensive method of disaster mitigation also includes the effect of vegetation. The pallet includes: avoiding hazards (hazard mapping, warning and alarming), appropriate land use and avoiding disaster-enhancing measures in the landscape and technical measures, which take into account their side-effects. The energy line is used as simple design theory. The Jiu-Jitsu principle is explained too. With this comprehensive method a more sustainable reduction of disasters seems possible.

关键词： Torrent complex system energyconcept energy dissipation energy line vegetation integrated debris flow counter-measure disaster mitigation

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Gap solitons of spin–orbit-coupled Bose–Einstein condensates in pT periodic potential

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Chinese physics B 2022年第1期31卷 140-145页

作者： S Wang Y h Liu T F Xu hebei Key Laboratory of Microstructural Material physics School of ScienceYanshan UniversityQinhuangdao 066004China School of Science Yanshan UniversityQinhuangdao 066004China

We numerically investigate the gap solitons in Bose–Einstein condensates(BECs)with spin–orbit coupling(SOC)in the parity–time(pT)-symmetric periodic *** find that the dep.h. and periods of the imaginary lattice have an important influence on the shape and stability of these single-peak gap solitons and double-peak gap solitons in the first band *** dynamics of these gap solitons are checked by the split-time-step Crank–Nicolson *** is proved that the dep.h. of the imaginary part of the pT-symmetric periodic potential gradually increase,and the gap solitons become *** the different periods of imaginary part hardly affect the stability of the gap solitons in the corresponding parameter interval.

关键词： gap solitons spin–orbit coupling pT-symmetric periodic potential

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经CR2激活MApKs与抑制hIV-gp160处理的CD4^+细胞增殖

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中华微生物学和免疫学杂志 2004年第4期24卷 304-310页

作者：罗敏华李太存陈明亮 h.Stoiber M.p.Dierich 苏先狮 Institute fǖr hygiene 中南大学湘雅医学院中南大学湘雅一医院皮肤科中南大学湘雅二医院传染科

目的　建立CR2稳定表达的hOS CR2、hOS CD4CR2细胞系 ,研究细胞中MApKs的活化和细胞增殖变化 ,阐明经CR2的信号传导、CR2的表达对hIV gp16 0等所致的CD4 +细胞的影响。方法　用哺乳动物细胞稳定转染法建立稳定表达CR2的hOS CR2、hOS CD4... 详细信息

目的　建立CR2稳定表达的hOS CR2、hOS CD4CR2细胞系 ,研究细胞中MApKs的活化和细胞增殖变化 ,阐明经CR2的信号传导、CR2的表达对hIV gp16 0等所致的CD4 +细胞的影响。方法　用哺乳动物细胞稳定转染法建立稳定表达CR2的hOS CR2、hOS CD4CR2细胞系 ,细胞经磁珠阳性纯化后 ,用FACS和Westernblot对CR2的表达进行鉴定。用pMA、10 %NhS、hIV gp16 0等处理细胞后 ,经Westernblot检测细胞的MApKs的活化水平 ;用CellTiter 96AqueousOneSolutionReagent检测和分析处理后细胞的增殖差异。结果　FACS检测和统计学方法分析结果表明CR2表达的阳性率高达96 %以上 ;Westernblot结果显示所建hOS CR2、hOS CD4CR2细胞系的CR2的表达水平与Raji细胞相近 ;细胞经pMA、预先激活补体的 10 %NhS处理细胞 ,发现在处理 10min时ERK、JNK、p38的活化达高峰 ;pD980 5 9、Wortmanin和抗 CR2能阻断ERK、JNK、p38的活化。hIV gp16 0、预先激活补体的 10 %NhS能相应激活hOS CR2 ,hOS CD4和hOS CD4CR2细胞ERK、JNK、p38,这些激活均可被相应的抗体所阻断 ;细胞增殖实验结果显示hIV gp16 0能抑制细胞增殖 (p hIV gp16 0所致的细胞增殖抑制 (p <0 .0 1)。结论　磁珠阳性纯化法可浓集稳定表达靶基因的细胞 ,提高阳?

关键词：补体受体信号传导蛋白激酶 hIV CD4^+细胞细胞增殖

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phase-field modeling of void evolution and swelling in materials under irradiation

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Science China(physics,Mechanics & Astronomy) 2011年第5期54卷 856-865页

作者： hENAGER Charles h Jr KhALEEL Mohammad pacific Northwest National Laboratory Richland WA 99352 USA

Void swelling is an important phenomenon observed in both nuclear fuels and cladding materials in operating nuclear reactors. In this work we develop a phase-field model to simulate void evolution and void volume change in irradiated materials. Important material processes, including the generation of defects such as vacancies and self-interstitials, their diffusion and annihilation, and void nucleation and evolution, have been taken into account in this model. The thermodynamic and kinetic properties, such as chemical free energy, interfacial energy, vacancy mobility, and annihilation rate of vacancies and interstitials, are expressed as a function of temperature and/or defect concentrations in a general manner. The model allows for parametric studies of critical void nucleus size, void growth kinetics, and void volume fraction evolutions. Our simulations demonstrated that void swelling displays a quasi-bell shape distribution with temperature often observed in experiments.

关键词： radiation void swelling vacancies interstitials phase-field model

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Formation of Non-Maxwellian Distribution and Its Role in Collisionless Driven Reconnection

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Communications in Computational physics 2008年第8期4卷 496-505页

作者： R.horiuchi h.Ohtani National Institute for Fusion Science Toki 509-52Japan The Graduate University for Advanced Studies Toki 509-52Japan

The dynamical evolution of collisionless driven reconnection is investigated by using an electromagnetic particle simulation code in a microscopic open *** in-plane electrostatic field is excited in the central region of current sheet under the influence of an external driving *** a result of the amplification of unmagnetized meandering motion by the electrostatic field particle distribution function is modified from the shifted Maxwellian to an anisotropic one in the current *** ion hole appears at the center of current sheet in the phase space,where distribution becomes two-peaked and no ions exist in low velocity region between two *** strongmodification of distribution function leads to the generation of off-diagonal components of pressure tensor term,which is one of major causes to violate frozen-in constraint and trigger collisionless reconnection.

关键词： Collisionless reconnection particle simulation open system multi-scale physics

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