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世界核心医学期刊文摘（儿科学分册） 2006年第11期2卷 59-60页

作者： Cauchi J. p.rikh D.H. Samuel M. gornall p. 王经纬 Dep.rtment of p.ediatric Surgery Birmingham Children's Hospital NHS Trust Steel House Lane B4 6NH BirminghamUnited Kingdom

Background: Outcome after gastroschisis rep.ir without general anesthesia is controversial, and p.blished conclusions are variable with no comp.rative studies. Aim: The aim of this study was to p.esent a comp.rative study evaluating outcome after gastroschisis rep.ir with and without general ***: An ambisp.ctive nonrandomized study of a cohort of 51 neonates born with gastroschisis between July 1998 and December 2003 was p.rformed. Twenty-four neonates (group.) had conventional reduction under general anesthesia, and 27(group.2) cotside minimal intervention reductions were without general anesthesia. Results: Group. were comp.rable regarding gestational age, birth weight, and quality of eviscerated bowel. Statistical significance (p.p. 1 and 2 with regard to age at reduction of gastroschisis(5.6 ±2.5 vs 3 ±1 hours) and time taken for comp.etion of gastroschisis reduction (58.1 ±15 vs 49 ±14 minutes). No statistical significance (p.> 0.05) was seen with resp.ct to start of feeds (10.4 ±3.6 vs 10.9 ±4.1 days), duration of total p.renteral nutrition (21.5 ±7.3 vs 22.4 ±6.8 days), and total hosp.tal(stay 29 ±10 vs 30 ±13 days). Admission to the intensive care unit was required in 92%in group.1 for 1 to 6 days vs 7%in group.2 for 3 to 6 days. There was 1 death in group.1(4%). Total hosp.tal cost in group.1 was ￡12,283 ±￡2438 vs￡6208 ±￡2120 in group.2 (p.= 0.013). Conclusions: Neonates with gastroschisis, whose bowel was reduced without general anesthesia, have similar outcomes to those whose bowel was reduced under general anesthesia. Both ap.roaches ap.ear to be safe and effective, but reduction without general anesthesia was cost-effective.

关键词：复位术比较性研究腹裂切除量重症监护完全胃肠外营养队列研究显著性差异

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