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Asymptotic Derivation of a Linear Plate Model for Soft Ferromagnetic Materials

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Chinese Annals of Mathematics,Series B 2018年第3期39卷 451-460页

作者： giuseppe GEYMONAT Francoise KRASUCKI Michele SERPILLI Laboratoire de Mecanique des Solides Ecole PolytechniqueCNRSUniversite Paris-Saclay91128 PalaiseauFrance Institut Montpellierain Alexander Grothendieck UMR-CNRS 5149Universite de Montpellier Place Eugene Bataillon34095 Montpellier Cedex 5France Department of Civil and Building Engineering and ArchitecturePolytechnic University of MarcheVia Brecce Bianche60131 AnconaItaly

The authors use the asymptotic expansion method by *** to obtain a Kirchhoff-Love-type plate model for a linear soft ferromagnetic *** also give a mathematical justification of the obtained model by means of a strong ... 详细信息

关键词： Asymptotic methods Plates Magnetoelasticity

OxInflammation in Alzheimer's disease

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Neural Regeneration Research 2023年第12期18卷 2709-2710页

作者： Carlo Cervellati Giovanni Zuliani giuseppe Valacchi Department of Translational Medicine and for Romagna University of FerraraFerraraItaly Department of Environmental Sciences and Prevention University of FerraraFerraraItaly Plants for Human Health Institute Animal Science DepartmentNC State UniversityKannapolisNCUSA Department of Food and Nutrition Kyung Hee UniversitySeoulSouth Korea

Oxlnflammation:definition and role in disease:Oxlnflammation has been introduced as a new term in the biomedical field to highlight the deep and mutual relationship between the dysregulation of redox and immune homeostasis(Valacchi et al.,2018).Regardless of which is the initial spark,inflammation cannot take place without a concomitant oxidative stress response and *** other words,they are sides of the same coin.

关键词： al. homeostasis inflammation

BACE1 role in Alzheimer’s disease and other dementias:from the theory to the practice

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Neural Regeneration Research 2021年第12期16卷 2407-2408页

作者： Carlo Cervellati giuseppe Valacchi Giovanni Zuliani Department of Translational Medicine and for Romagna University of FerraraFerraraItaly Department of Biomedical and Specialist Surgical Sciences University of FerraraFerraraItalyPlants for Human Health InstituteAnimal Science DepartmentNC State UniversityKannapolisNCUSA

Beta-site amyloid precursor protein(APP)cleaving enzyme-1(BACE1):brief overview on the biology and its role in Alzheimer’s disease(AD)pathogenesis:AD is a multifactorial and multifaceted disease,with a complex and still not completely understood pathogenesis(Cervellati et al.,2016;Iturria-Medina et al.,2016).Multiple hypotheses have been proposed to explain the pathobiology of the disease.

关键词： BACE1 Alzheimer al.

Force Analysis and Curve Design for Laying Pipe in Loop Laying Head of Wire Rod Mills

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Chinese Journal of Mechanical Engineering 2019年第2期32卷 36-52页

作者： Shuangji Yao Marco Ceccarelli giuseppe Carbone Bin Ma College of Material Science and Engineering Yanshan University Qinhuangdao 066004 China University of Cassino and South Latium Cassino 03043 Italy HBIS Group Co. Ltd Handan 056001 China

Laying head is a high-precision engineering device in hot-rolled high speed wire rod production line. Previously research works are focused on the laying pipe wear-resisting. Laying pipe curve design method based on wire rod kinematics and dynamics analyses are not reported before. In order to design and manufacture the laying pipe, the motion and force process of the wire rod in the laying pipe should be studied. In this paper, a novel approach is proposed to investigate the force modeling for hot-rolled wire rod in laying pipe. An idea of limited element method is used to analysis and calculates the forces between laying pipe inner surface and wire rod. The design requirements of laying pipe curve for manufacturing are discussed. The kinematics and dynamics modeling for numerical calculation are built. A laying pipe curve equation is proposed by discussing design boundary conditions. Numerical results with di erent laying pipe curves design parameters are plotted and compared. The proposed approach performs good result which can be applied for laying pipe curve design and analysis for engineering application.

关键词： Wire rod mills Laying head Laying pipe curve design Wire rod force analysis

Towards automated validation of charted soundings:Existing tests and limitations

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Geo-Spatial Information Science 2019年第4期22卷 290-303,I0006页

作者： Christos Kastrisios Brian Calder giuseppe Masetti Peter Holmberg Center for Coastal and Ocean Mapping/UNH-NOAA Joint Hydrographic Center University of New HampshireDurhamNHUSA U.S.Department of Commerce National Oceanic and Atmospheric AdministrationNational Ocean ServiceOffice of Coast SurveyHydrographic Survey DivisionSeattleWAUSA

The nautical chart is one of the fundamental tools in navigation used by mariners to plan and safely execute *** compilation follows strict cartographic constraints with the most prominent being that of the ***,the cartographer is called to make the selection of the bathymetric information for portrayal on charts in a way that,at any location,the expected water depth is not deeper than the source *** validate the shoal-biased pattern of selection two standard tests are used,*** triangle and edge *** date,some efforts have been made towards the automation of the triangle test,but the edge test has been largely *** the context of research on a fully automated solution for the compilation of charts at different scales from the source information,this paper presents an algorithmic implementation of the two tests for the validation of selected *** a case study with real-world data,it presents the improved performance of the implementation near and within depth curves and coastlines and points out the importance of the edge test in the validation *** also presents the,by definition,intrinsic limitation of the two tests as part of a fully automated solution and discusses the need for a new test that will complement or supersede the existing ones.

关键词： Automated nautical cartography nautical chart generalization chart safety constraint sounding generalization nautical surface test sounding selection category zone of confidence

Optimal flow conditions of a tracheobronchial model to reengineer lung structures

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Acta Mechanica Sinica 2017年第2期33卷 284-294页

作者： Stefano Casarin Federico Aletti giuseppe Baselli Marc Garbey LASIE UMR CNTS Univeristy of La Rochelle La Rochelle France Houston Methodist Hospital Research Institute Houston TX USA Dipartimento di Elettronica Informazione e Bioingegneria Politecnico di Milano Milan Italy

The high demand for lung transplants cannot be matched by an adequate number of lungs from donors. Since fully ex-novo lungs are far from being feasible, tissue engineering is actively considering implantation of engineered lungs where the devitalized structure of a donor is used as scaffold to be repopulated by stem cells of the receiving patient. A decellularized donated lung is treated inside a bioreactor where transport through the tracheobronchial tree (TBT) will allow for both deposition of stem cells and nourishment for their subsequent growth, thus developing new lung tissue. The key concern is to set optimally the boundary conditions to utilize in the bioreactor. We propose a predictive model of slow liquid ventilation, which combines a one-dimensional (1-D) mathematical model of the TBT and a solute deposition model strongly dependent on fluid velocity across the tree. With it, we were able to track and drive the concentration of a generic solute across the airways, looking for its optimal distribution. This was given by properly adjusting the pumps’ regime serving the bioreactor. A feedback system, created by coupling the two models, allowed us to derive the optimal pattern. The TBT model can be easily invertible, thus yielding a straightforward flow/pressure law at the inlet to optimize the efficiency of the bioreactor.

关键词： Bioreactor Lung rehabilitation Network flow Tissue engineering Transport of solute

Optimal dual antiplatelet therapy strategy in elderly patients with acute coronary syndrome

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Journal of Geriatric Cardiology 2021年第3期18卷 210-218页

作者： Monica Verdoia Rocco Gioscia giuseppe De Luca Cardiologia e UnitàCoronarica Ospedale degli InfermiASL BiellaItaly/Division of CardiologyAzienda Ospedaliera-Universitaria“Maggiore della Carità”Universitàdel Piemonte OrientaleNovaraItaly

One out of three hospitalizations for acute coronary syndrome(ACS)involve nowadays elderly patients,carrying together a significant burden of comorbidities and a higher risk of *** particular,both ischemic and haemorrhagic risk are markedly enhanced in advanced age,and strictly interconnected,challenging the management of dual antiplatelet therapy(DAPT)in these *** recent development of several therapeutic options in terms of duration and combination of antiplatelet agents have offered a wider spectrum of opportunities for a more individualized approach in the management of DAPT after an ACS,although the criteria for the selection of the most appropriate strategy in each patient still lack *** particular,dose-adjustment,early aspirin discontinuation,laboratory-driven tailoring and shorter or extended DAPT have been addressed with promising safety and efficacy *** present review provides an updated overview on the emerging evidencefrom randomized clinical trials and subanalyses dedicated to the management of DAPT in elderly patients presenting with ACS.

关键词： patients coronary markedly

Effect of stepover and torch tilting angle on a repair process using WAAM

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Advances in Manufacturing 2022年第4期10卷 541-555页

作者： Francesco Baffa giuseppe Venturini Gianni Campatelli Emanuele Galvanetto Department of Industrial Engineering University of FlorenceFlorenceItaly

To sustain the transition to a greener economy and greener manufacturing,it is necessary to develop new approaches and technologies to repair metal components;this will result in a drastic reduction in energy and material *** this study,wire arc additive manufacturing(WAAM)was used to deposit a layer of new material on an existing surface,with the objective of finding the optimal configuration that maximized the layer quality and material *** parameters considered are the stepover among the deposited beads and the inclination of the torch with respect to the repaired *** inclination angle is crucial when repairing complex surfaces,like those of a mold,owing to accessibility issues,the torch cannot be maintained orthogonal to the surfaces along the entire *** configurations were tested in order to assess the quality of the materials in terms of the presence of material voids,depth of penetration,and the heat affected zone(HAZ)and to understand the effects of these variables on the material efficiency and thickness of the repairing *** should be noted that by adopting deposition parameters set to have a low heat input,the use of a tilting angle has beneficial effects on the quality of the deposited layer and the process *** and geometrical measurements were carried out to assess the effect of these two variables depositing a layer of plain carbon steel.

关键词： Wire arc additive manufacturing(WAAM) Repairing·Torch inclination Stepover Remanufacturing

Synthesis and characterization of lanthanum bonded agar-carbomer hydrogel:a promising tool for biomedical research

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Journal of Rare Earths 2011年第3期29卷 259-264页

作者： Filippo Rossi Marco Santoro Tommaso Casalini giuseppe Perale Dipartimento di Chimica Materialied Ingegneria Chimica"G.Natta"Politecnico di MilanoVia Mancinelli7

Agar-Carbomer（branched poly（acrylic acid）） hydrogel,an injectable bio-resorbable scaffold with a controlled nanostructure specifically designed for neural cell housing,was developed together with a new protocol for building three dimensional biohybrid cell/hydrogel *** order to overcome classic structural analysis inconveniences due to the high water amount,which affects instruments results and reliability,agar-Carbomer hydrogels were synthesized by microwave-assisted block copolymerization together with La3＋ *** glycol,glycerol and buffered saline solution were used as cross-linking agents and solvent,*** properties were not affected by the presence of lanthanum,and were checked via swelling and rheological ***,the presence of La3＋ within the polymeric network was characterized by thermogravimetric analysis,environmental scanning electron microscopy and Fourier transformed infrared *** results showed that the rare earth presented uniform distribution in the hydrogel network due to the formation of chemical bonds after polymerization without being modified its luminescence emission spectrum that allowed hydrogel *** results made the obtained host-guest system a useful tool for analytical research studies concerning regenerative medical applications that could also be potentially taken up with in vivo experiments.

关键词： hydrogel acrylic acid agarose lanthanum luminescence drug delivery rare earths