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Assessment of voluntary rhythmic muscle contraction-induced exercising blood flow variability measured by Doppler ultrasound

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Open Journal of Molecular and Integrative Physiology 2013年第4期3卷 158-165页

作者： Takuya Osada Bengt Saltin goran Radegran Department of Sports Medicine for Health Promotion Tokyo Medical UniversityTokyoJapan The Copenhagen Muscle Research Centre RigshospitaletUniversity of CopenhagenCopenhagenDenmark The Clinic for Heart Failure and Valvular Disease Skane University HospitalLundSweden Department of Cardiology Clinical SciencesLund UniversityLundSweden

Given recent technological developments, ultrasound Doppler can provide valuable measurements of blood velocity/flow in the conduit artery with high temporal resolution. In human-applied science such as exercise physiology, hemodynamic measurements in the conduit artery is commonly performed by blood flow feeding the exercising muscle, as the increase in oxygen uptake (calculated as a product of arterial blood flow to the exercising limb and the arterio-venous oxygen difference) is directly proportional to the work performed. The increased oxygen demand with physical activity is met through a central mechanism, an increase in cardiac output and blood pressure, as well as a peripheral mechanism, an increase in vascular conductance and oxygen extraction (a major part of the whole exercising muscles) from the blood. The increase in exercising muscle blood flow in relation to the target workload (quantitative response) may be one indicator in circulatory adjustment for the ac- tivity of muscle metabolism. Therefore, the determination of local blood flow dynamics (potential oxygen supply) feeding repeated (rhythmic) muscle contractions can contribute to the understanding of the factors limiting work capacity including, for instance, muscle metabolism, substance utilization and magnitude of vasodilatation in the exercising muscle. Using non-invasive measures of pulsed Doppler ultrasound, the validity of blood velocity/flow in the forearm or lower limb conduit artery feeding to the muscle has been previously demonstrated during rhythmic muscle exercise. For the evaluation of exercising blood flow, not only muscle contraction induced internal physiological variability, or fluctuations in the magnitude of blood velocity due to spontaneous muscle contraction and relaxation induced changes in force curve intensity, superimposed in cardiac beat-by-beat, but also the alterations in the blood velocity (external variability) due to a temporary sudden change in the achieved workloa

关键词： Exercising Blood Flow Doppler Ultrasound Muscle Contraction Blood Flow Alterations

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油田钻井废水的物化组合处理技术

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北京化工大学学报（自然科学版） 2005年第4期32卷 19-23,28页

作者：李秀金 goran Nasser 康佳丽李荣平北京化工大学化学工程学院北京100029

对化学混凝膜分离、化学混凝活性碳吸附组合工艺处理油田钻井废水进行了试验研究。通过对4种混凝剂混凝对比试验,确定最佳混凝剂为聚合氯化铁(PFC)。在pH=8.1,助凝剂聚丙烯酰胺(PAM,质量分数0.5%)投加量w(PAM)为10mL·L-1,PFC(质量分数1... 详细信息

对化学混凝膜分离、化学混凝活性碳吸附组合工艺处理油田钻井废水进行了试验研究。通过对4种混凝剂混凝对比试验,确定最佳混凝剂为聚合氯化铁(PFC)。在pH=8.1,助凝剂聚丙烯酰胺(PAM,质量分数0.5%)投加量w(PAM)为10mL·L-1,PFC(质量分数10%)投加量w(KC87)为10mL·L-1的条件下,化学需氧量(COD)去除率达95.3%。混凝出水经膜分离深度处理后,没有达到排放要求。混凝出水经活性炭深度处理获得了较好的效果。在选取的4种活性炭中,KC87粉末状果壳活性炭的吸附效果最好,在吸附时间为1h、投加量w(KC87)为3g·L-1的条件下,可使混凝出水中COD的去除率达75.3%。经PFC化学混凝和KC87活性炭吸附组合工艺处理后,废水COD总去除率达到97.4%,其他污染物也得到了明显的去除,使得最终出水达到了国家废水综合排放标准一级水平。

关键词：钻井废水混凝膜分离吸附活性炭

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Exploitation and Abuse of Children in ＂Entrepreneurial＂ Purposes

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Chinese Business Review 2012年第10期11卷 891-899页

作者： goran Kutnjak Matija Radovic Diana Blaskovic Faculty of Economics Rijeka Rijeka Croatia Pharmacy "Ilona Lenac" Labin Croatia

The society of today often likes to brand itself as modem, advanced, civilized, or a society of positive changes. However, it is a fact that the world is confronted with huge contradictions that oppose such qualifications. Obviously, one of the most striking and almost unbelievable realities tells us about inhumane and uncivilized actions of child exploitation in ＂entrepreneurial＂ purposes in the widest range of exploitation and abuse. Current period of economic crisis tells us even more about the rising crisis of moral, which is, in statistical terms, confirmed by a rising number of exploited children in a global framework, and even in some national frameworks as well. With that, some positive results about the diminishing number of exploited children are devaluated. The question is what are the ＂limits＂ of such behavior of groups, organizations, and individuals whose behavior is, obviously, tolerated in the frameworks of certain national economies. Does this behavior have clarity as a part of modem society？ Or, even more severe, for how long can we as a society close our eyes in front of such facts？ Do we even have the right？ In this paper, the authors strive towards focusing and objectifying the global problem of exploitation and abuse of children in ＂entrepreneurial＂ purposes, primarily with the purpose of updating all parts of the society of this paradox and the need of raising the awareness and teaching all relevant factors--from institutions to individuals, with the purpose of resolving and more neutralize the equivalents of this uncivilized and non-entrepreneurial ＂phenomenon＂, as well as approaching the same in the framework of different actions with broadest measures possible and with all disposable assets.

关键词： entrepreneurship children exploitation abuse forms of exploitation

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Multicriteria Methods for Distributed Generation Resources Optimization

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Journal of Energy and Power Engineering 2013年第5期7卷 987-994页

作者： Aleksandar Janjic Suzana Savic goran Janackovic Faculty of Electronic Engineering University of Nis Nig 18000 Serbia Faculty of Occupational Safety in Nis University of Nis Nis 18 000 Serbia

The optimization process of embedded, or DG （distributed generation） is a very complex task, and it should be evaluated and compared by means of multi-criteria methods of analysis. The classical method for selection is usually based only on a single criterion analysis, and it is defined by thermal or economic aspects. The problem of optimal dispatch of DG is typical example of optimization, because it differs from the classical problem of generation dispatch in the power system, due to the specific criteria related to the DG interconnection. The most important goals are to maximize the renewable production and to minimize the total cost, while satisfying additional constraints related to the operation of a distribution network. As there are many DGs in a distribution network, it is very complicated to decide the optimal DG outputs to satisfy all the criteria and constraints imposed by the distribution network. Another problem is the lack of the dispatcher control over DGs, and very often, the only available action is to switch on or off the generator. Finally, network operator and DG owner perspective are often opposed regarding appropriate control action in the network. In this paper, a multicriteria decision support based on AHP （analytical hierarchical processes） method is proposed for the choice of the dispatching action. The method is illustrated on the choice of the DG to be switched off in the case or reverse power flow.

关键词： AHP optimal dispatch distributed generation multicriteria decision reverse power flow.

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Liver disease in the era of COVID-19: Is the worst yet to come?

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World Journal of Gastroenterology 2021年第36期27卷 6039-6052页

作者： Ivana Mikolasevic Dorotea Bozic Tajana Pavić Alen Ruzic goran Hauser Marija Radic Delfa Radic-Kristo Melanija Razov-Radas Zeljko Puljiz Sandra Milic Department of Gastroenterology Clinical Hospital Center RijekaRijeka 51000Croatia Department of Gastroenterology University Hospital MerkurZagreb 10000Croatia Faculty of Medicine University of RijekaRijeka 51000Croatia Department for Gastroenterology and Hepatology University Hospital Center SplitSplit 21000Croatia Department of Gastroenterology and Hepatology Faculty of MedicineSestre Milosrdnice University Hospital CenterZagreb 10000Croatia Clinic for Cardiology University Hospital Center RijekaRijeka 51000Croatia Faculty of Health Studies University of RijekaRijeka 51000Croatia Faculty of Medicine Zagreb 10000Croatia Department of Hematology University Hospital MerkurZagreb 10000Croatia Division of Gastroenterology General Hospital ZadarZadar 23000Croatia University of Split School of MedicineSplit 21000Croatia

The global social,economic and political crises related to coronavirus disease 2019(COVID-19)presumably had more indirect than direct negative impacts on health *** lifestyle changes,social isolation and distancing,and individual and global financial crises resulted in robust populations forfeiting healthy habits and seeking comfort in alcoholic beverages,drugs and unhealthy *** inevitable consequences are increases in the incidence of nonalcoholic fatty liver disease,viral hepatitis,acute alcoholic hepatitis,liver cirrhosis decompensation and ultimately liver-related *** inaccessibility of regular clinical and sonographic monitoring systems has caused difficulties in the treatment of patients with chronic liver disease(CLD)and has prevented prompt hepatocellular carcinoma detection and treatment.A dramatic reduction in the number of liver donors and the transformation of numerous transplantation centers into COVID-19 units drastically decreased the rate of orthotopic liver *** indirect,unavoidable effects of the COVID-19 pandemic in the following years have yet to be *** efforts in the management of patients with liver disease in order to overcome the inevitable COVID-19-related morbidity and mortality that will follow have yet to be *** questions regarding the impact of the COVID-19 pandemic on liver disease *** most important question for general CLD patients is:How will the modification of clinical practice during this pandemic affect the outcomes of CLD patients?This article reviews the influence of COVID-19 on patients with liver disease during the pandemic,with particular emphasis on the disease course associated with pandemic resolution.

关键词： COVID-19 Pandemic Chronic liver disease Management Impact Liverrelated mortality

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Rectal cancer and Fournier's gangrene- current knowledge and therapeutic options

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World Journal of Gastroenterology 2015年第30期21卷 9002-9020页

作者： Tomislav Bruketa Matea Majerovic goran Augustin Department of Surgery University Hospital Center Zagreb Department of Internal Medicine University Hospital Center Zagreb Department of Surgery Division of Gastroin- testinal SurgeryUniversity Hospital Center Zagreb School of Medicine University of Zagreb

Fournier's gangrene(FG) is a rapid progressive bacterial infection that involves the subcutaneous fascia and part of the deep fascia but spares the muscle in the scrotal,perianal and perineal region. The incidence has increased dramatically,while the reported incidence of rectal cancer-induced FG is unknown but is extremely low. Pathophysiology and clinical presentation of rectal cancer-induced FG per se does not differ from the other causes. Only rectal cancer-specific symptoms before presentation can lead to the diagnosis. The diagnosis of rectal cancer-induced FG should be excluded in every patient with blood on digital rectal examination,when urogenital and dermatological causes are excluded and when fever or sepsis of unknown origin is present with perianal symptomatology. Therapeutic options are more complex than for other forms of FG. First,the causative rectal tumor should be removed. The survival of patients with rectal cancer resection is reported as 100%,while with colostomy it is 80%. The preferred method of rectal resection has not been defined. Second,oncological treatment should be administered but the timing should be adjusted to the resolution of the FG and sometimes for the healing of plastic reconstructive procedures that are commonly needed for the reconstruction of large perineal,scrotal and lower abdominal wall defects.

关键词： Fournier's gangrene Necrotizing fasciitis Proctological examination Necrotizing soft tissueinfections Oncological treatment Rectal cancer Surgical treatment Reconstructive surgery

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Implications of a Crisis on Small Businesses in the European Union and Republic of Croatia

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Chinese Business Review 2013年第3期12卷 172-185页

作者： goran Kutnj ak Matija Radovic Dejan Miljenovic University of Rijeka Rijeka Croatia

Until the early 1990s Croatia has been neglecting, and even underestimating the significance, the role, the needs, and the results of small businesses （small and medium entrepreneurship）. Complete attention was focused on big companies. Relatively late, in 2002, small businesses, within the statutory legislation, have gotten its appropriate legal status and economic relevance. Today it is treated as a ＂basic necessity＂ of every society and a generator of economic development. But, economic crisis that has been present since 2008 has manifested all of its negativities, which has reflected on the present state of the economy, the whole society, and it is also shown from the results and some relevant indicators.

关键词： mall- and medium-entrepreneurship European Union Republic of Croatia crisis

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Mast cells and multiple sclerosis in females and males

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World Journal of Neuroscience 2012年第3期2卷 145-149页

作者： Per goran Krüger Sverre Mork Institute of Biomedicine and Institute of Pathology University of BergenBergenNorway

Mast cells were observed in autopsies from 11 females and 8 males. We confirm earlier observations that mast cells are more frequent in close vicinity to MS-plaques. In these plaque-border zone areas, defined as the area within 1 mm distance of the actual plaques, the average number of mast cells was 2.34/mm2 in males and 4.77/mm2 in females, which in average is appr. 10 times more than earlier observed in MS. The difference in number of mast cells between females and males is significant (p < 0.005) and is of interest since females are more inclined to developing MS than males. Mast cells were rare in areas without visible plaques. The mast cells were preferably located close to capillaries and venules. A mechanism for the probable role of mast cells, based on diet-factors and mast cell mediators in the pathogenesis of MS is discussed.

关键词： Mast Cells Multiple Sclerosis Quantification Females Males Treatment

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Dynamics of freshwater snails and Schistosoma infection prevalence in schoolchildren during the construction and operation of a multipurpose dam in central Côte d’Ivoire

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Infectious Diseases of Poverty 2017年第1期6卷 810-818页

作者： Nana R.Diakite Mirko S.Winkler Jean T.Coulibaly Negnorogo Guindo-Coulibaly Jürg Utzinger Eliezer K.N’goran Laboratoire de Zoologie et Biologie Animale Unitede Formation et de Recherche BiosciencesUniversite Felix Houphouët-Boigny22 BP 522Abidjan 22Cote d’Ivoire Swiss Tropical and Public Health Institute P.O.BoxCH-4002BaselSwitzerland University of Basel P.O.BoxCH-4003BaselSwitzerland Departement Environnement et Sante Centre Suisse de Recherches Scientifiques en Cote d’Ivoire01 BP 1303Abidjan 01Cote d’Ivoire

Background:The construction and operation of small multipurpose dams in Africa have a history of altering the transmission of water-based diseases,including *** current study was designed to investigate the abundance and dynamics of schistosomiasis intermediate host snails and Schistosoma infections in humans during the construction and the first years of operation of a small multipurpose dam in Côte d’***:The study was carried out in Raffierkro and four neighbouring villages in central Côte d’Ivoire between 2007 and *** were collected by two experienced investigators using scoops and forceps for 15 min at each *** were identified at genera and,whenever possible,species level,and subjected to testing for cercarial *** aged 6-15 years were examined once every year for Schistosoma haematobium and *** infection,using urine filtration and duplication Kato-Katz thick smears,***,551 adults were examined for Schistosoma infection before(June 2007)and 359 individuals 2 years after dam construction(June 2009).Results:Overall,1700 snails belonging to nine different genera were collected from 19 sampling ***(potential intermediate host snails of ***)and Pila were the most common genera,whereas Biomphalaria(potential intermediate host snail of ***),Lymnaea,Physa and Melanoides were found in two *** the first-year sampling period,65 snails were collected,of which 13(20%)were schistosomiasis intermediate *** subsequent years,out of 1635 snails collected,1079(66%)were identified as potential intermediate host for schistosomiasis,but none were shedding *** prevalence of *** among adults in the study area was low(0.4%in 2007 and 0.3%in 2009),whereas the prevalence of *** declined from 13.9%to 2.9%in this two-year ***:The low prevalence of schistosomiasis in humans and the absence of infected intermediate host s

关键词： Schistosomiasis Intermediate host snail Transmission Water resources development and management Multipurpose dam Cote d’Ivoire

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Landfill Gas Modelling in Municipal Landfill of Novi Sad

Landfill Gas Modelling in Municipal Landfill of Novi Sad

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7th World Congress on Recovery, Recycling and Re-integration

作者： goran Vujic Mirjana Vojinovic Miloradov Biljana Tomasevic goran Cabradi Bogdana Vujic Faculty of Technical Sciences Trg Dositeja Obradovica 6 Novi Sad Vojvodina 21000 Yugoslavia Faculty of Technical Sciences Trg Dositeja Obradovica 6 Novi Sad Vojvodina 21000 Yugoslavia Public Company for Solid Waste Management CISTOCA Sentandrejski Put 3 Novi Sad Vojvodina 21000 Yugoslavia Public Company for Solid Waste Management CISTOCA Sentandrejski Put 3 Novi Sad Vojvodina 21000 Yugoslavia Provincial Secretariat for Environmental Protection and Sustainable Development Bulevar Mihajla Pupina 16 Novi Sad Vojvodina 21000 Yugoslavia

Novi Sad landfill has the annual lying down of 100,000 t of municipal solid waste, occupying the area of 56 ha., and has the average solid waste layer of 6 m. It has been in use since 1986. Analyzing the increase in population with the amount of 1.20 kg waste per resident, it is expected that the area for keeping the municipal solid waste would generate 141,000 t by 2021 Furthermore, using the experience and analysis it is calculated that the annual amount of municipal solid waste laid down in the landfill in the period from 1986 to 1995 was approximately 90,000 t/a Novi Sad landfill is one out of the two landfills in Serbia fulfilling the main conditions for properly lying down. Sanitary improvements were made, and one part of the landfill was covered by inert material. At the landfill ground, drilling was done and gas wells were placed. One of the first projects at the landfill is to determine the structure and the amount of landfill gases with the aim of gaining data. Data processing would present useful information for the future managing of municipal solid waste lying down. Landfill gas censoring monitors and analyses filtered water from the landfill. After landfill gas censoring and water analysis, data processing continues towards making risk assessment, total amount of separated CH4 and CO2 estimation, and analyzing possible landfill gas usage for energetic or some other feasible purposes. According to stated data of the amount of municipal solid waste, measured data and foreign experiences, recommendations for further managing of this landfill have been presented especially for use of CH4 in energy purposes.

关键词： landfill gas, energy, modeling

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