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Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression

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Cellular & Molecular Immunology 2016年第6期13卷 862-870页

作者： Jeong-Min Lee Young-Saeng Jang Bo-Ra Jin Sun-Jin Kim Hyeon-Jin Kim Bo-Eun Kwon Hyun-Jeong Ko Sung-il Yoon Geun-Shik Lee Woan-Sub Kim goo-Young Seo Pyeung-Hyeun Kim Department of Molecular Bioscience School of Biomedical Science Kangwon National University Chuncheon Republic of Korea Laboratory of Microbiology and Immunology College of Pharmacy Kangwon National University Chuncheon Republic of Korea Department of Systems Immunology College of Biomedical Science Kangwon National University Chuncheon 200-701 Republic of Korea College of Veterinary Medicine Kangwon National University Chuncheon Gangwon 200-701 Republic of Korea Department of Animal Life and Environmental Science College of Agriculture and Life Science Hankyong National University Anseong-si 456-749 Republic of Korea

Lactoferrin （LF） and retinoic acid （RA） are enriched in colostrum, milk, and mucosal tissues. We recently showed that LF-induced IgA class switching through binding to betaglycan （transforming growth factor-beta receptor III, TpRIII） and activation of canonical TGF-p signaling. We investigated the combined effect of LF and RA on the overall IgA response. An increase in IgA production by LF was further augmented by RA. This combination effect was also evident in Ig germ-line α （GLa） transcription and GLa promoter activity, indicating that LF in cooperation with RA increased IgA isotype switching. We subsequently found that RA enhanced TβRIII expression and that this increase contributed to LF-stimulated IgA production. In addition to the IgA response, LF and RA in combination also enhanced the expression of the gut-homing molecules C-C chemokine receptor 9 （CCR9） and a4β7 on B cells. Finally, peroral administration of LF and RA enhanced the frequency of CCR9＋ IgA＋ plasma cells in the lamina propria. Taken together, these results suggest that LF in cooperation with RA can contribute to the establishment of gut IgA responses.

关键词： gut homing molecule IgA lactoferrin retinoic acid TGF-β receptor

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家用电脑与游戏机 2000年第1期 26-27页

作者： Sara goo

Impacts of Pig Manure-Based Liquid Fertilizer Agricultural Application on the Water Quality of Agricultural Catchment

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Journal of Environmental Protection 2013年第2期4卷 195-200页

作者： Min-Kyeong Kim Soon-Ik Kwon Hyen-Cheng Chun goo-Bok Jung Kee-Kyung Kang Department of Agricultural Environment National Academy of Agricultural Science Rural Development Administration Suwon South Korea

This study was conducted to understand the effect of the livestock liquid fertilizer treatment at field-scale up to catchment-scale on the water quality properties. Cultivated paddy rice and upland plots located in Gyeonggi province, Korea were treated with two different liquid fertilizers, SP (Liquid fertilizer with storage process) and SCB (Liquid fertilizer with slurry composting and bio-filtration process). Plots with no fertilizer (control A) and chemical fertilizer (control B) were also prepared for comparison. Water quantity and quality were monitored at the catchment outlet for assessing the effect on water quality of stream water. As a result, the losses of N and P and the values of EC (Electronic Conductivity) in the surface drainage water from paddy rice plots treated with SP and SCB were higher than those from the control plots (A and B). In addition, the losses of N and P by the runoff water from upland plots with SP and SCB treatment were higher than those from control plots (A and B). The nutrient outflow from paddy rice fields and uplands with application of liquid pig manure was higher than those from the control plots (A and B). Particularly, the outflow from uplands may directly affect the water quality in neighboring streams. This caused the major eutrophication problem in stream water. In conclusion, it is necessary to establish the proper management practices to prevent the nutrient losses from agricultural fields and the pollutants against water environments.

关键词： Liquid Fertilizer Livestock Manure Paddy Field Upland Water Quality

SYNERGISTIC GAINS FROM JOINT OPERATION OF MULTIPLE RESERVOIR SYSTEMS IN HAN RIVER

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SYNERGISTIC GAINS FROM JOINT OPERATION OF MULTIPLE RESERVOIR...

International Symposium on Modern Technology of Dams--The 4th EADC Symposium

作者： Lee.Gwang Man Cha.Hyung Sun Kang,Min goo Kwater Jonmindong 462-1.YusungguDaejeonKorea. K-water Chuncheon.Korea.-82-33-260-3750. Univ.of Illinois at Urbana-Champaign ILUSA.

＜正＞In this study,a methodology was developed to evaluate effects in water use aspect attained by real joint-operation of multi-purpose *** this methodology,to evaluate effects from the viewpoint of water supply and flow condition,the rate of satisfaction at water requirement and the stability of flow condition were measured for the Hart River dam *** evaluate effects from the view point of hydropower generation,total hydropower generation produced in a basin was used as an evaluation *** indexes were applied to evaluating results of joint-operation of Soyanggang and Chungju dams in the klan River *** real joint-operation results from 2001 to 2004 were compared with the results attained by single dam operation and optimal operation model using three evaluation *** results comparing the stability of flow condition with varying operation methods showed that each flow condition in real joint-operation and optimal operation model was more stable than that in single dam operation.

关键词： Effects of joint-operation Evaluation index Dam operation method The Han River Basin

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比你轻一些

收藏 2014年第6期 84-91页

作者： Lin goo.Studio

沈懿和贺晶,两位学贯中西的首饰设计学院派,受了七年专业训练,却从来无法说服她们自己,首饰是什么大不了的东西。在和人的关系中,首饰说的好话有限,恰如其份,比你少重要那么一点儿的首饰,就是她们想帮你做的。"goo.垢"是沈懿和贺晶合作... 详细信息

沈懿和贺晶,两位学贯中西的首饰设计学院派,受了七年专业训练,却从来无法说服她们自己,首饰是什么大不了的东西。在和人的关系中,首饰说的好话有限,恰如其份,比你少重要那么一点儿的首饰,就是她们想帮你做的。"goo.垢"是沈懿和贺晶合作的首饰品牌。这个不常见的英文字来自Sonic Youth的专辑"goo"。而"垢"在字典中,指日常生活中来自人身体上细小而又没用的东西,比如咬下的指甲、拔掉的眉毛。它们没用无聊,但人们做这些事儿时专心投入而满足。现在沈懿在斯得哥尔摩,贺晶在阿姆斯特丹。时差并不是距离,她们的产品已经开始在北京和斯德哥尔摩同步经营及发售。

关键词：首饰服饰沈懿设计师

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《文心雕龙》“文体讹滥”说探原

四川师范大学学报（社会科学版） 2022年第4期49卷 153-163页

作者：陈贝高林广内蒙古师范大学文学院

“文体讹滥”是刘勰对江左文风的基本判断,这一认识贯穿《文心雕龙》文体论始终,其目的性和重要性自不待言。刘勰持广义文体观,其所谓“文体”兼及体统、体貌、体裁等;其“讹滥”说,是对六朝及江左文风之背离经典、追新逐奇,“极貌写物... 详细信息

“文体讹滥”是刘勰对江左文风的基本判断,这一认识贯穿《文心雕龙》文体论始终,其目的性和重要性自不待言。刘勰持广义文体观,其所谓“文体”兼及体统、体貌、体裁等;其“讹滥”说,是对六朝及江左文风之背离经典、追新逐奇,“极貌写物”、“文贵形似”,“诗杂仙心”、“率多浮浅”等倾向的现实指陈。刘勰的“文体讹滥”说,标举了宪章典诰“准的”、“雅润”的文章规范,强调了“极其心实”、“体周事核”的文体创作要求,树立了“风清骨峻”、“街华佩实”的美学风范,提供了“晓变昭体”“望今制奇”的矫讹良方,具有切实的现实意义。其垂示典诰之训、正本矫讹的文学主张,正是《文心雕龙》的精髓所在。

关键词：《文心雕龙》 “文体讹滥”说正本矫讹

采用铜导电油墨在改性柔性基材上实现喷墨印刷

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中国印刷与包装研究 2010年第5期2卷 76-78页

作者： goo Yongsung LEE Youngin KIM Namwoo LEE Kunjae YOO bongyoung HONG Sungjei KIM Joong-do CHOA Yongho 王晓芳 Division of Materials and Chemical Engineering Hanyang University Information Display Research Center Korea Electronics Technology InstituteSeongnamRepublic of Korea Digital Solution R&D Center Samsung Techwin Co.LTDYongin 446-712Republic of Korea

本文采用铜导电油墨在聚酰亚胺(PI)薄膜上进行喷墨印刷形成铜导电层,并研究基于铜络合物的铜导电油墨与柔性基材的相关性。本研究首先采用氧等离子体对PI薄膜表面进行改性,以测试接触角来表征改性前后薄膜表面性能的变化。通过优化等离... 详细信息

本文采用铜导电油墨在聚酰亚胺(PI)薄膜上进行喷墨印刷形成铜导电层,并研究基于铜络合物的铜导电油墨与柔性基材的相关性。本研究首先采用氧等离子体对PI薄膜表面进行改性,以测试接触角来表征改性前后薄膜表面性能的变化。通过优化等离子体反应参数使接触角降低。再利用喷墨印刷在改性前后PI薄膜上沉积铜导线,在200℃氢气环境下进行热处理,印制铜线发生烧结而收缩。采用光学显微镜(OM)、场发射扫描电子显微镜(FESEM)、X射线衍射(XRD)、非接触式三维轮廓仪和四点探针分析铜导线形状、微观结构、晶体结构及电导率。结果表明,经氧等离子体改性的PI基材上可成功沉积具有纯铜相的连续铜导线且具有良好的烧结微观结构,同时确定了铜导电油墨与基材表面性能的相关性。

关键词：印刷导电油墨等离子体表面改性

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直肠癌术后吻合口漏发生的危险因素

中华胃肠外科杂志 2018年第4期21卷 384-387页

作者：陶凯雄高金波华中科技大学同济医学院附属协和医院胃肠外科武汉430022

吻合口漏是直肠癌术后常见的并发症之一。近年来直肠癌外科手术技术及理念有了明显的进步和发展，特别是直肠全系膜切除、双吻合器技术等微创技术的应用，使得直肠癌术后生存率及保肛率得到明显提高,但吻合口漏的发生率却没有显著改善... 详细信息

吻合口漏是直肠癌术后常见的并发症之一。近年来直肠癌外科手术技术及理念有了明显的进步和发展，特别是直肠全系膜切除、双吻合器技术等微创技术的应用，使得直肠癌术后生存率及保肛率得到明显提高,但吻合口漏的发生率却没有显著改善。吻合口漏的发生与很多因素有关，其中包括患者个体相关因素，如男性患者、肥胖因素、术前营养评分低以及Ⅲ-Ⅴ级美国麻醉医师协会（AsA）分级等：疾病相关因素，如肿瘤位置低、肿瘤直径〉3cm、术前放化疗以及有无合并症等；手术相关因素，如开腹或腹腔镜手术、吻合口肠管血供、吻合口张力、预防性造口、手术时间、术中出血量、术中并发症、术中污染以及吻合器械的选择和使用等。充分了解吻合口漏发生的相关危险因素，对于降低吻合口漏的发生至关重要。对于存在危险因素的患者，要及时采取相应的预防措施，以期尽可能地降低吻合口漏的发毕．

关键词：直肠肿瘤手术吻合口漏危险因素预防措施

Robot-Assisted Laparoscopic Adrenalectomy:15 cases

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Robot-Assisted Laparoscopic Adrenalectomy:15 cases