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Evaluation of Simulated CO_2 Concentrations from the CarbonTracker-Asia Model Using In-situ Observations over East Asia for 2009–2013

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Advances in Atmospheric Sciences 2019年第6期36卷 603-613页

作者： Samuel Takele KENEA Young-Suk OH Jae-Sang RHEE Tae-Young goo Young-Hwa BYUN Shanlan LI Lev D.LABZOVSKII Haeyoung LEE Robert F.BANKS Climate Research Division National Institute of Meteorological Sciences Environmental Meteorology Research Division National Institute of Meteorological Sciences Meteorology Department Delta Air LinesInc.

The CarbonTracker(CT) model has been used in previous studies for understanding and predicting the sources, sinks, and dynamics that govern the distribution of atmospheric CO_2 at varying ranges of spatial and temporal scales. However, there are still challenges for reproducing accurate model-simulated CO_2 concentrations close to the surface, typically associated with high spatial heterogeneity and land cover. In the present study, we evaluated the performance of nested-grid CT model simulations of CO_2 based on the CT2016 version through comparison with in-situ observations over East Asia covering the period 2009–13. We selected sites located in coastal, remote, inland, and mountain areas. The results are presented at diurnal and seasonal time periods. At target stations, model agreement with in-situ observations was varied in capturing the diurnal cycle. Overall, biases were less than 6.3 ppm on an all-hourly mean basis, and this was further reduced to a maximum of 4.6 ppm when considering only the daytime. For instance, at Anmyeondo, a small bias was obtained in winter, on the order of 0.2 ppm. The model revealed a diurnal amplitude of CO_2 that was nearly flat in winter at Gosan and Anmyeondo stations, while slightly overestimated in the summertime. The model's performance in reproducing the diurnal cycle remains a challenge and requires improvement. The model showed better agreement with the observations in capturing the seasonal variations of CO_2 during daytime at most sites, with a correlation coefficient ranging from 0.70 to 0.99. Also, model biases were within-0.3 and 1.3 ppm, except for inland stations(7.7 ppm).

关键词： model evaluation in-situ observations CarbonTracker East Asia

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中国经济增长:一个文化变迁的分析框架

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南京社会科学 2007年第7期 17-25页

作者：高波南京大学长江三角洲经济社会发展研究中心教授博导南京210093

本文应用文化成本和文化变迁理论对近代以来中国的经济停滞和经济增长进行分析,认为是三次文化变迁有效降低了人们的文化成本,为制度创新、技术创新创造了条件,从而促进了经济增长。从这一认识出发,作者指出文化创新是实现中国经济增长... 详细信息

本文应用文化成本和文化变迁理论对近代以来中国的经济停滞和经济增长进行分析,认为是三次文化变迁有效降低了人们的文化成本,为制度创新、技术创新创造了条件,从而促进了经济增长。从这一认识出发,作者指出文化创新是实现中国经济增长的重要前提。

关键词：经济增长文化成本文化变迁

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Comparative study of rendezvous techniques in post-liver transplant biliary stricture

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World Journal of Gastroenterology 2012年第41期18卷 5957-5964页

作者： Jae Hyuck Chang In Seok Lee Ho Jong Chun Jong Young Choi Seung Kyoo Yoon Dong goo Kim Young Kyoung You Myung-Gyu Choi Sok Won Han Department of Internal Medicine College of MedicineThe Catholic University of KoreaSeoul 137-701South Korea Department of Radiology College of MedicineThe Catholic University of KoreaSeoul 137-701South Korea Department of Surgery College of MedicineThe Catholic University of KoreaSeoul 137-701South Korea

AIM： To investigate the usefulness of a new rendezvous technique for placing stents using the Kumpe （KMP） catheter in angulated or twisted biliary strictures. METHODS： The rendezvous technique was performed in patients with a biliary stricture after living donor liver transplantation （LDLT） who required the exchange of percutaneous transhepatic biliary drainage catheters for inside stents. The rendezvous technique was performed using a guidewire in 19 patients （guidewire group） and using a KMP catheter in another 19 （KMP catheter group）. We compared the two groups retrospectively. RESULTS： The baseline characteristics did not differ between the groups. The success rate for placing insidestents was 100% in both groups. A KMP catheter was easier to manipulate than a guidewire. The mean pro- cedure time in the KMP catheter group （1012 s, range： 301-2006 s） was shorter than that in the guidewire group （2037 s, range： 251-6758 s, P = 0.022）. The cu- mulative probabilities corresponding to the procedure time of the two groups were significantly different （P = 0.008）. The factors related to procedure time were the rendezvous technique method, the number of inside stents, the operator, and balloon dilation of the stric- ture （P 〈 0.05）. In a multivariate analysis, the rendez- vous technique method was the only significant factor related to procedure time （P = 0.010）. The procedural complications observed included one case of mild acute pancreatitis and one case of acute cholangitis in the guidewire group, and two cases of mild acute pancre- atitis in the KMP catheter group. CONCLUSION： The rendezvous technique involving use of the KIVlp catheter was a fast and safe method for placing inside stents in patients with LDLT biliary stric- ture that represents a viable alternative to the guide- wire rendezvous technique,

关键词： Rendezvous Biliary stricture Liver trans-plantation Endoscopic retrograde cholangiography Percutaneous transhepatic biliary drainage

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Exercise improves the effects of testosterone replacement therapy and the durability of response after cessation of treatment： a pilot randomized controlled trial

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Asian Journal of Andrology 2017年第5期19卷 602-607页

作者： Dae-Yeon Cho Jeong Kyun Yeo Seung Ik Cho Jae Eun Jung Sang Jin Yang Doo Hwan Kong Jeong Ku Ha Jin goo Kim Min Gu Park Inje University Sanggye Paik Hospital Department of Urology Seoul Korea Inje University Seoul Paik Hospital Department of Urology Seoul Korea KonKuk University Medical Center Department of Orthopedics Seoul Korea Inje University Seoul Paik Hospital Department of Orthopedics Sports Medical Center Seoul Korea

The effects of the combination of exercise and TRT on symptoms of late-onset hypogonadism （LOH） and the durability of response after cessation of TRT were investigated. A total of fifty patients with erectile dysfunction （ED） who had a sedentary lifestyle and low serum total testosterone （T） levels were enrolled and followed for 20 weeks. Patients were randomly divided into two groups; all of them received T gel for 12 weeks and it was discontinued for 8 weeks. Patients assigned to Group II were offered a supervised exercise program for 20 weeks. Measurement of serological testing was performed and self-assessment questionnaires and Global Assessment Question （GAQ） were asked. Baseline characteristics and the initial symptom scores showed no significant difference between the two groups. Serum total T levels and the symptom scores were increased at 12 weeks in both groups, and Group II showed better results with statistical significance. There was a decrease in T levels and worsening of symptom scores at week 20 compared to week 12 in both groups, and Group II showed better results with statistical significance. On the GAQ, Group II showed higher ratio of ＂yes＂ at week 12 and the same tendency was sustained at week 20 with significant difference between two groups. The combination of exercise and TRT showed significant improvements in serum T levels and LOH symptoms compared to TRT alone. In addition, these improvements were maintained in the combination group with continuous exercise, even after cessation of TRT.

关键词： erectile dysfunction exercise hypogonadism testosterone

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Clinical outcome after pulmonary metastasectomy from primary hepatocellular carcinoma:Analysis of prognostic factors

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World Journal of Gastroenterology 2008年第37期14卷 5717-5722页

作者： Jong-Bum Kwon Khun Park Young-Du Kim Jong-Hee Seo Seok-Whan Moon Deog-Gon Cho Yong-Whan Kim Dong-goo Kim Seung-Kew Yoon Hyeon-Woo Lim Department of Thoracic and Cardiovascular Surgery the Catholic University of KoreaSeoul 137-701 Korea Department of Surgery the Catholic University of KoreaSeoul 137-701 Korea Department of Internal Medicine the Catholic University of KoreaSeoul 137-701 Korea Department of Preventive Medicine the Catholic University of KoreaSeoul 137-701 Korea

AIM： To review the surgical outcomes in terms of the surgical indications and relevant prognostic factors. METHODS： Sixteen patients underwent therapeutic lung surgery between March 1999 and May 2006. The observation period was terminated on May 31, 2007. The surgical outcomes and the clinicopathological factors were compared. RESULTS： There was no mortality or major morbidity encountered in this study. The mean follow-up period after metastasectomy was 26.7 ＋ 28.2 （range： 1-99 mo）, and the median survival time was 20 mo. The 1- and 5-year survival rates were 56% and 26%, respectively. At the end of the follow-up, 1 patient died from hepatic failure without recurrence, 6 died from hepatic failure with a recurrent hepatocellular carcinoma （HCC）, and 4 died from recurrent HCC with cachexia. Among several clinical factors, Kaplan Meier analysis revealed as a treatment for the that liver transplantation primary lesion, grade of cell differentiation, and negative evidence HBV infection were independent predictive factors. On Cox＇s proportional hazard model, there were no significant factors affecting survival after pulmonary metastasectomy in patients with HCC. CONCLUSION： A metastasectomy should be performed before other treatments in selected patients, Although not significant, patients with liver transplantation of a primary HCC survived longer, Liver transplantation might be the most beneficial modality that can offer patients better survival, A multi- institutional and collaborative study would be needed for identifying clinical prognostic factors predicting survival in patients with HCC and lung metastasis.

关键词： Hepatocellular carcinoma Pulmonary metastasis Metastasectomy Liver transplantation Thoracoscopy

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Transverse Flux Induction Coil for Uniform Bar Heating Excluding Edge

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Journal of Iron and Steel Research International 2012年第S2期19卷 754-757页

作者： PARK Jong-Soo BAE Jin-Su CHO Un-Kwan HA Tae-Jong KIM goo-Hwa Process Engineering Design Research Group Engineering Research Center

This work particularly focuses on compensating Joule heat in under-heated areas occurred when thin steel bar is(<20 mm)heated by transverse flux induction heater(TFIH).The under-heated areas take place in range of 50~150 mm from the both edges,so Transverse Flux Induction Coil(TFIC)including a magnetic core is proposed and optimized to supplement this *** solutions on the electromagnetic field are obtained numerically by commercial code MAXWELL 3D software from ANSYS *** then,verified experimentally by pilot-scale tests,in which the TFIH was manufactured with a nominal power of 100 kW at a fundamental frequency of 1 ***,TFIC having geometrically the optimized magnetic core made the heating pattern U-shaped,so could supply a desirable temperature profile for the rolling process.

关键词： Transverse Flux Induction heating(TFIH) induction coil magnetic core uniform heating

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Severe thrombocytopenia before liver transplantation is associated with delayed recovery of thrombocytopenia regardless of donor type

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World Journal of Gastroenterology 2008年第37期14卷 5723-5729页

作者： Jae Hyuck Chang Jong Young Choi Hyun Young Woo Jung Hyun Kwon Chan Ran You Si Hyun Bae Seung Kew Yoon Myung-Gyu Choi In-Sik Chung Dong goo Kim Department of Internal Medicine College of Medicine the Catholic University of Korea505 Banpo-Dong Seocho-Gu Seoul 137-040 Korea Department of Surgery College of Medicine the Catholic University of Korea505 Banpo-Dong Seocho-Gu Seoul 137-040 Korea

AIM： To compare the recovery of thrombocytopenia and splenomegaly during long-term follow-up after liver transplantation in patients receiving a living donor transplant or a cadaveric donor transplant. METHODS： This was a retrospective cohort study of 216 consecutive liver transplant patients who survived for 〉 6 mo after transplantation; 169 received a liver transplant from a living donor and 47 from a cadaveric donor. The platelet counts or spleen volumes were examined before transplant, i, 6, and 12 mo after transplant, and then annually until 5 years after transplant. RESULTS： The mean follow-up period was 49 mo （range, 21-66）. Platelet counts increased continuously for 5 years after orthotopic liver transplant. The restoration of platelet counts after transplant was significantly slower in patients with severe pretransplant thrombocytopenia （〈 50000/μL） until 4 years after transplant （P = 0.005）. Donor type did not significantlyaffect the recovery of platelet count and spleen volume in either patient group. In multivariate analysis, pretransplant severe thrombocytopenia （〈 50000/μL） was an independent factor associated with sustained thrombocytopenia （P 〈 0.001, odds ratio 6.314; confidence interval, 2.828-14.095）. Thrombocytopenia reappeared after transplant in seven patients with portal flow disturbance near the anastomosis site. CONCLUSION： Our study suggests that severe thrombocytopenia before transplant is closely associated with delayed recovery of platelet count after transplant and donor type did not affect the recovery of thrombocytopenia. The reappearance of thrombocytopenia after transplant should be considered a possible indicator of flow disturbance in the portal vein.

关键词： Liver transplantation Thrombocytopenia Splenomegaly Hypersplenism

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Caenorhabditis elegans deep lipidome profiling by using integrative mass spectrometry acquisitions reveals significantly altered lipid networks

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Journal of Pharmaceutical Analysis 2022年第5期12卷 743-754页

作者： Nguyen Hoang Anh Young Cheol Yoon Young Jin Min Nguyen Phuoc Long Cheol Woon Jung Sun Jo Kim Suk Won Kim Eun goo Lee Daijie Wang Xiao Wang Sung Won Kwon College of Pharmacy Seoul National UniversitySeoul08826Republic of Korea School of Pharmaceutical Sciences Shandong Analysis and Test CenterQilu University of Technology(Shandong Academy of Sciences)Jinan250014China Biological Engineering Technology Innovation Center of Shandong Province Heze Branch of Qilu University of Technology(Shandong Academy of Sciences)HezeShandong274000China

Lipidomics coverage improvement is essential for functional lipid and pathway construction.A powerful approach to discovering organism lipidome is to combine various data acquisitions,such as full scan mass spectrometry(full MS),data-dependent acquisition(DDA),and data-independent acquisition(DIA).Caenorhabditis elegans(***)is a useful model for discovering toxic-induced metabolism,highthroughput drug screening,and a variety of human disease *** determine the lipidome of *** and investigate lipid disruption from the molecular level to the system biology level,we used integrative data *** methyl-tert-butyl ether method was used to extract L4 stage *** after exposure to triclosan(TCS),perfluorooctanoic acid,and nanopolystyrene(nPS).Full MS,DDA,and DIA integrations were performed to comprehensively profile the *** lipidome by Q-Exactive Plus *** annotated lipids were then analyzed using lipid ontology and pathway *** annotated up to 940 lipids from 20 lipid classes involved in various functions and *** biological investigations revealed that when *** were exposed to nPS,lipid droplets were disrupted,whereas plasma membrane-functionalized lipids were likely to be changed in the TCS treatment *** nPS treatment caused a significant disruption in lipid ***,glycerophospholipid,and ether class lipids were those primarily hindered by ***,toxicant exposure frequently involved numerous lipid-related pathways,including the phosphoinositide 3-kinase/protein kinase B *** conclusion,an integrative data acquisition strategy was used to characterize the *** lipidome,providing valuable biological insights into hypothesis generation and validation.

关键词： Caenorhabditis elegans Lipidomics Data-dependent acquisition Data-independent acquisition

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经学的比兴与文学的比兴——《文心雕龙·比兴篇》新说

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人文杂志 2007年第4期 118-122页

作者：郜积意北京大学中文系

在《文心雕龙.比兴篇》中,刘勰区分了比义和比体,扬比义、贬比体。此种论述与汉代经学的比兴论不同,比、兴均为诗之六义,不存在价值的高低。刘勰所以如此立论,是因为他以辞赋为考察对象,故刘勰提倡"宗经",也和汉代经学的经典观有明显区... 详细信息

在《文心雕龙.比兴篇》中,刘勰区分了比义和比体,扬比义、贬比体。此种论述与汉代经学的比兴论不同,比、兴均为诗之六义,不存在价值的高低。刘勰所以如此立论,是因为他以辞赋为考察对象,故刘勰提倡"宗经",也和汉代经学的经典观有明显区别。注意到此种区别,对于把握〈比兴篇〉、〈宗经篇〉的涵义及其相关的文学思想史问题,将不无启迪。

关键词：刘勰《文心雕龙》比兴

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Self-aligned single-electrode actuation of tangential and wineglass modes using PMN-PT

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微系统与纳米工程(英文) 2023年第3期9卷 43-49页

作者： Ozan Erturk Kilian Shambaugh Ha-Seong Park Sang-goo Lee Sunil A.Bhave OxideMEMS Lab Purdue UniversityWest LafayetteINUSA Polytec Inc. IrvineCAUSA iBULe Photonics Company Ltd. Incheon 21999South Korea

Considering the evolution of rotation sensing and timing applications realized in micro-electro-mechanical systems(MEMS),flexural mode resonant shapes are outperformed by bulk acoustic wave(BAW)counterparts by achieving higher frequencies with both electrostatic and piezoelectric *** the 1-30 MHz range,which hosts BAW gyroscopes and timing references,piezoelectric and electrostatic MEMS have similar transduction ***,when designed intelligently,electrostatic transduction allows self-alignment between electrodes and the resonator for various BAW modes,misalignment is inevitable regarding piezoelectric transduction of BAW modes that require electrode *** this paper transverse piezoelectric actuation of[011]oriented single crystal lead magnesium niobate-lead titanate(PMN-PT)thin film disks are shown to excite the tangential mode and family of elliptical compound resonant modes,utilizing a self-aligned and unpatterned electrode that spans the entire disk *** resonant mode coupling is achieved by employing a unique property of[011]PMN-PT,where the in-plane piezoelectric coefficients have opposite *** 1-port disk transducers,RF reflection measurements are performed that demonstrate the compound mode family shapes in the 1-30 MHz *** verification of mode transduction is achieved using in-plane displacement measurements with Polytec’s laser Doppler vibrometer(LDV).While the tangential mode achieves a 40°/s dithering rate at 335 kHz resonant frequency,the n=2 wine-glass mode achieves 11.46 nm tip displacement at 8.42 MHz resonant frequency on a radius of 60μm disk resonator in air.A single electrode resonator that can excite both tangential and wine-glass modes with such metrics lays the foundation for a BAW MEMS gyroscope with a built-in primary calibration stage.

关键词： resonator electrode piezoelectric

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