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Feedback between tidal hydrodynamics and morphological changes induced by natural process and human interventions in a wave-dominated tidal inlet: Xiaohai, Hainan, China

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Acta Oceanologica Sinica 2009年第3期28卷 93-113页

作者： gong Wenping SHEN Jian JIA Jianjun School of Marine Science Sun Yat-Sen University Guangzhou 510275 China Virginia Institute of Marine Science College of William and Mary Gloucester Point VA23062 USA Key Laboratory of Submarine Geosciences Second Institute of Oceanography State OceanicAdministration Hangzhou 310012 China

The feedback between morphological evolution and tidal hydrodynamics in a wave-dominated tidal inlet, Xiaohai, China is investigated through data analysis and numerical model experiments. Historically, Xiaohai Inlet had two openings, located at the north and south of Neizhi Island （a rocky outcrop）, respectively. The evolution of Xiaohai Inlet was dominated by the natural process before 1972. In addition to the natural process, human interventions, including the closure of the north opening, 50% of freshwater reduction, and increase of land reclamation, have altered tidal hydrodynamics and morphological evolution since 1972. A series of numerical model simulations were conducted to investigate the influence of morphological changes on the hydrodynamics and the influence of human activities on the inlet evolution. The natural process has caused narrowing and shoaling of the inlet throat, development of the flood-tidal delta, and shoaling of the tidal channel inside the lagoon. Human interventions have accelerated these changes. Consequently, the tidal propagation from the offshore into the lagoon has been impeded and the tidal energy has been dissipated substantially. Tidal current has changed from ebb-dominant to flood-dominant in most parts of the inlet system whereas the inlet throat has remained as ebb-dominant, the tidal prism has decreased consistently, and sediment has continued to deposit inside the inlet. As a result, the changes of morphology, hydrodynamics, and sediment transport show a positive feedback. The human interventions have had both advantageous and adverse influences on the stability of the inlet. The closure of the North Opening has decreased the longshore sediment input to the inlet, and increased the tidal prism, ebb velocity, and sediment transport in the south opening, thus enhancing the inlet＇s stability. However, reducing the river discharge and landfill of the tidal flats has resulted in a decrease of the tidal prism, the ebb velocity, a

关键词： morphological evolution tidal hydrodynamics ELCIRC Hainan China

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Full Quantum Theory of Molecular Hot-Electroluminescence in Scanning Tunneling Microscope Tunnel Junctions

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Chinese Journal of Chemical Physics 2015年第5期28卷 -页

作者： gong Chen Xiao-guang Li Zhen-chao Dong International Center for Quantum Design of Functional Materials Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of China Hefei 230026 China International Center for Quantum Design of Functional Materials Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of China Hefei 230026 ChinaShenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055China

The pursuit of nanoscale photonics and molecular optoelectronics has stimulated a lot of interests in scanning tunneling microscope (STM) induced molecular emission. In this work, we have introduced a full quantum mechanical approach instead of the previous semiclassical theory to consider the quantized surface plasmon modes in this system. By considering the mutual interactions between a single molecule and the quantized surface plasmon, we have studied the molecular electroluminescence from STM tunnel junctions. Due to the coupling to the surface plasmons, the spontaneous emission rate and the fluorescence intensity of the molecule are both enormously enhanced. In particular, we show that when the radiative decay rate becomes comparable to the vibrational damping rate, hot-electroluminescence can be observed. All these findings are believed to be instructive for further developments of both molecular electronics and photonics.

关键词： Scanning tunneling microscope induced luminescence Master equation Surface plasmon Hot-electroluminescence

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Interference with the formation of the epididymal microenvironment——a new strategy for male contraception?

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Asian Journal of Andrology 2000年第1期2卷 39-45页

作者： X.D.gong G.P.H.Leung B.L.Y.Cheuk P.Y.D.Wong Department of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong ChinaDepartment of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong ChinaDepartment of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong ChinaDepartment of Phsiology The Chinese University of Hong Kong Shatin N. T. Hong Kong China

The cystic fibrosis transmembrane conductance regulator (CFIR) or the small conductance cAMP-activated chlo-ride channel encoded by the CFTR gene has been shown to play an important role in the formation of the epididymalfluid microenvironment. Recent work in our laboratory has shown that this protein is also expressed by developing germcells indicating a role of this protein in spermatogenesis. In view of the fact that the CFTR gene has a far reaching andwidespread effect on human reproduction, understanding the role of CFTR in the male reproductive tissues and its inter-vention by pharmacological agents can open a new avenue of research into the development of novel male contracep-tives. (Asian J Androl 2000; 2: 39 - 45 )

关键词： epididymis cyclooxygenase contraception cystic fibrosis transmembrane conductance regulator

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肺动脉CTA与D-二聚体对肿瘤患者肺栓塞诊断的一致性研究

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中国CT和MRI杂志 2025年第1期23卷 72-74页

作者：张建泉沈智勇龚海鹏张慧王丽南通市肿瘤医院影像科江苏南通226361

目的分析肺动脉CT angiography(CTA)与D-二聚体在肿瘤患者急性肺动脉栓塞诊断中的一致性。方法收集南通市肿瘤医院2019-2021年住院的肿瘤患者中,临床怀疑肺栓塞的连续80例患者作为研究对象,所有患者进行D-二聚体检测、肺动脉CTA检查,... 详细信息

目的分析肺动脉CT angiography(CTA)与D-二聚体在肿瘤患者急性肺动脉栓塞诊断中的一致性。方法收集南通市肿瘤医院2019-2021年住院的肿瘤患者中,临床怀疑肺栓塞的连续80例患者作为研究对象,所有患者进行D-二聚体检测、肺动脉CTA检查,使用Kappa检验比较两者对急性肺栓塞诊断的一致性。结查92.5%(74/80)的患者两者检查一致,其中两者均阳性(诊断为肺动脉栓塞)62例,两者均阴性(诊断为非肺动脉栓塞)12例。7.5%(6/80)的患者两者检查不一致,其中D-二聚体阳性而肺动脉CTA阴性(两肺动脉及其分支未见明显栓子形成)4例;D-二聚体阴性而肺动脉CTA阳性(肺动脉分支栓子形成)2例。Kappa值为0.75,P<0.01。结论D-二聚体与肺动脉CTA对肺动脉栓塞检查具有较高的一致性。肺动脉CTA在肺栓塞的诊断中具有重要价值。少部分D-二聚体阴性患者,如有相应临床症状,仍需及时肺动脉CTA,以排除肺栓塞可能。

关键词：肺动脉CTA D-二聚体肺栓塞肿瘤

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A quantitative method for storm surge vulnerability assessment – a case study of Weihai city

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International Journal of Digital Earth 2017年第5期10卷 539-559页

作者： Jin Liu Jian-Hua gong Jian-Ming Liang Yi Li Lin-Chong Kang Li-Li Song Sui-Xiang Shi State Key Laboratory of Remote Sensing Science Institute of Remote Sensing and Digital EarthChinese Academy of SciencesBeijingPeople’s Republic of China National Marine Data and Information Service TianjinPeople’s Republic of China University of Chinese Academy of Sciences BeijingPeople’s Republic of China

In traditional vulnerability assessments,a synthetic index method is usually used to select all types of social and economic indexes so that more aspects can be covered;however,the requisite social and economic data are not always available or are not highly relevant to the studied geographical space,which makes it difficult to conduct quantitative *** this paper,a spatial value density assessment method was developed to improve the hazard of place ***,a three-dimensional(3D)model of a coastal city was obtained using oblique airborne photogrammetry and image-based 3D reconstruction and then,architecture footprints were employed to extract the geometric information of each individual ***,a vulnerability assessment system was established to quantitatively account for the aggregate economic value of a selected set of urban surface *** geographic information system(GIS)techniques,the aggregate value of these urban features within each geographic unit can be accurately calculated to quantify the exposure and vulnerability of coastal cities to storm surge.A vulnerability assessment was conducted using Weihai city as an *** study shows that vulnerability assessment accuracy was greatly improved by downscaling the assessment granularity from county-level administrative districts to a 1-km grid.

关键词： Storm surge vulnerability assessment oblique photogrammetry 3D-GIS Weihai city

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Comparative study on hemodynamic environments around patient-specific carotid atherosclerotic plaques with different symmetrical features

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Medicine in Novel Technology and Devices 2021年第3期11卷 182-188页

作者： Xianghui gong Zhuqing Liang Yawei Wang Chi Zhang Sheng Xie Yubo Fan Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education Beijing Advanced Innovation Centre for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Radiology China-Japan Friendship HospitalBeijingChina

Atherosclerotic plaque near the carotid sinus is a key risk factor for ischemic *** disturbed hemodynamic environments around atherosclerotic plaque had been investigated in many studies,the effect of their symmetrical features,especially longitudinal asymmetrical characteristics,had not been comparatively *** this study,three-dimensional carotid bifurcation models were established based on CT images of three patients with 50%stenosis and with different symmetrical features of carotid atherosclerotic plaques including concentric plaque,eccentric plaque,or eccentric longitudinal asymmetrical plaque.A healthy subject was chosen as the *** shear stress(WSS)and oscillating shear index in the regions of upstream,downstream,downstream shoulders and regions around the point of maximum stenosis were *** results indicated that the maximum WSS around the eccentric longitudinal asymmetrical plaque were 8.6 times larger than that of the eccentric plaque and 1.9 times larger than that of the concentric *** the distributions of WSS and OSI around the eccentric longitudinal asymmetric plaque were more disordered than those of the *** results highlighted the risk of the eccentric longitudinal asymmetrical plaque on plaque development and rupture and might provide a new index for evaluating the development of atherosclerosis.

关键词： Carotid atherosclerosis Hemodynamic environments Symmetrical characteristic Eccentricity index

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Phosphorite generative processes around the Precambrian-Cambrian boundary in South China: An integrated study of Mo and phosphate O isotopic compositions

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Geoscience Frontiers 2021年第5期12卷 237-263页

作者： Haiying Yang Jiafei Xiao Yong Xia Zhuojun Xie Qinping Tan Jianbin Xu Shan He Shengwei Wu Xiqiang Liu Xingxiang gong State Key Laboratory of Ore Deposit Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China School of Earth Sciences Yunnan UniversityKunming650500China School of Qilu Transportation Shandong UniversityJinan 250061China University of Chinese Academy of Sciences Beijing 101408China Reserve Bureau of Land and Mineral Resources of Guizhou Province Guiyang 550081China

Large phosphorite deposits in Central Guizhou,China,were formed around the Precambrian/Cambrian boundary(PC/C),including the Ediacaran(Doushantuo stage)and early Cambrian(Gezhongwu stage).Among them,Gezhongwu phosphorite from Zhijin are enriched in rare earth elements(REE)plus yttrium(REY),reaching 3.503 million *** phosphorites have attracted great attention,the specific sources P and REY remained *** determine the P and REY sources and establish a phosphogenic model of PC/C phosphorite,we present an integrated dataset of Mo and phosphate O isotopes for the first time,along with carbonate C and O isotopes,geology,petrology,and *** all samples,d18Op,Y/Ho,and Zr/Hf decreased from the Ediacaran to the early Cambrian,indicating increased terrigenous weathering fluxes while decreased upwelling water ***,terrigenous weathering delivery significantly elevated marine REY concentrations in the Cambrian in *** Ceanom and d98/95Mo suggest that seawater was oxidized in the later Ediacaran and became entirely oxic in the early *** positive feedback between oxygen levels in atmosphere and primary productivity caused progressive oxygenation in ocean-atmosphere system and enable phosphorites to be formed by different *** show that the Lower Doushantuo consist of abiotic intraclasts and exhibited“seawaterlike”REY types,indicating abiological and mechanical reworking *** Upper Doushantuo and Gezhongwu Formation contained mainly microbial debris and abiogenic intraclasts,and exhibit “hat-shaped”REY plots,suggesting microbially mediated *** on this data set,we developed a phosphogenic model illustrating formation of these two phosphorite deposits,wherein the Lower Doushantuo phosphorite formed through the reworking of pre-existing phosphatic sediments in anoxic and abiotic ocean,whereas the Upper Doushantuo and Gezhongwu phosphorite formed via microbial metabolisms in oxic and bio

关键词： Doushantuo formation Gezhongwu formation Phosphorite Ore-forming material origin Phosphate O isotope Mo isotope

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Orthorhombic 3-LiV2O5 as Cathode Materials in Lithium Ion Batteries： Synthesis and Property

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Chinese Journal of Chemical Physics 2013年第5期26卷 597-600,I0004页

作者： Na Li Hua-xu gong Yi-tai Qian Department of Chemistry University of Science and Technology of China Hefei 230026 China

The rod-like and bundle-like v-LiV205 were synthesized via a simple solvothermal process- ing. The rod-like 7-LiV205 with diameter of 500-800 nm and the bundle-like architectures are composed of several of order-attached rods with diameter of 100-600 nm. ＂y-LiV205 were synthesized using LiOH.H20, NH4VO3, HNO3, C2H5OH without and with PVP as raw materials. At the same time, the actual formation mechanism of Y-LiV205 was also investigated. As the cathode materials for lithium ion batteries, the bundle-like Y-LiV205 prepared with PVP delivers a better electrochemical performance, which has an initial dis charge capacity of 269.3 mAh/g at a current density of 30 mA/g and is still able to achieve 228 mAh/g after the 20th cycle. The good electrochemical properties of the as-synthesized Y-LiV205 coupled with the simple, relatively low temperature, and low cost of the prepara tion method may make this material a promising candidate as a cathode material for lithium ion batteries.

关键词： Lithium ion battery Electrochemical property Cathode material 7-LiV2O5

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Evodiamine Inhibits Angiotensin Ⅱ-Induced Rat Cardiomyocyte Hypertrophy

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Chinese Journal of Integrative Medicine 2018年第5期24卷 359-365页

作者： HE Na gong Qi-hai ZHANG Feng ZHANG Jing-yi LIN Shu-xian HOU Hua-hua WU Qin SUN An-sheng Key Laboratory of Basic Pharmacology of Guizhou Departmentof Pharmacology Zunyi Medical College Zunyi GuizhouProvince (563099) China

Objective: To investigate the effects of evodiamine(Evo), a component of Evodiaminedia rutaecarpa(Juss.) Benth, on cardiomyocyte hypertrophy induced by angiotensin Ⅱ(Ang Ⅱ) and further explore the potential mechanisms. Methods: Cardiomyocytes from neonatal Sprague Dawley rats were isolated and characterized, and then the cadiomyocyte cultures were randomly divided into control, model(Ang Ⅱ 0.1 μmol/L), and Evo(0.03, 0.3, 3 μmol/L) groups. The cardiomyocyte surface area, protein level, intracellular free calcium([Ca]i) concentration, activity of nitric oxide synthase(NOS) and content of nitric oxide(NO) were measured, respectively. The m RNA expressions of atrial natriuretic factor(ANF), calcineurin(CaN), extracellular signal-regulated kinase-2(ERK-2), and endothelial nitric oxide synthase(e NOS) of cardiomyocytes were analyzed by real-time reverse transcriptionpolymerase chain reaction. The protein expressions of calcineurin catalytic subunit(CnA) and mitogen-activated protein kinase phosphatase-1(MKP-1) were detected by Western blot analysis. Results: Compared with the control group, Ang Ⅱ induced cardiomyocytes hypertrophy, as evidenced by increased cardiomyocyte surface area, protein content, and ANF m RNA expression; increased intracellular free calcium([Ca]i) concentration and expressions of CaN m RNA, CnA protein, and ERK-2 m RNA, but decreased MKP-1 protein expression(P<0.05 or P<0.01). Compared with Ang Ⅱ, Evo(0.3, 3 μmol/L) significantly attenuated Ang Ⅱ-induced cardiomyocyte hypertrophy, decreased the [Ca]i concentration and expressions of CaN m RNA, CnA protein, and ERK-2 m RNA, but increased MKP-1 protein expression(P<0.05 or P<0.01). Most interestingly, Evo increased the NOS activity and NO production, and upregulated the e NOS m RNA expression(P<0.05). Conclusion: Evo significantly attenuated Ang Ⅱ-induced cardiomyocyte hypertrophy, and this effect was partly due to promotion of NO production, reduction of [Ca]i concentration, and inhibition of CaN and

关键词： evodiamine cardiomyocyte hypertrophy angiotensin Ⅱ calcineurin extracellular signal regulated kinase-2 nitric oxide

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Role of macrophages in peripheral nerve injury and repair

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Neural Regeneration Research 2019年第8期14卷 1335-1342页

作者： Ping Liu Jiang Peng gong-Hai Han Xiao Ding Shuai Wei Gang Gao Kun Huang Feng Chang Yu Wang Shanxi Medical University Taiyuan Shanxi Province China Inst让ute of Orthopedics Chinese PLA General Hospital Beijing China Kunming Medical University Kunming Yunnan Province China Shihezi University Medical College Shihezi Xinjiang Uygur Autonomous Region China Department of Orthopaedic Surgery Shanxi Provincial People's Hospital Shanxi Medical University Taiyuan Shanxi Province China Anhui Medical University Air Force Clinical College Hefei Anhui Province China

Resident and inflammatory macrophages are essential effectors of the innate immune system. These cells provide innate immune defenses and regulate tissue and organ homeostasis. In addition to their roles in diseases such as cancer, obesity and osteoarthritis, they play vital roles in tissue repair and disease rehabilitation. Macrophages and other inflammatory cells are recruited to tissue injury sites where they promote changes in the microenvironment. Among the inflammatory cell types, only macrophages have both pro-inflammatory (Ml) and anti-inflammatory (M2) actions, and M2 macrophages have four subtypes. The co-action of Ml and M2 subtypes can create a favorable microenvironment, releasing cytokines for damaged tissue repair. In this review, we discuss the activation of macrophages and their roles in severe peripheral nerve injury. We also describe the therapeutic potential of macrophages in nerve tissue engineering treatment and highlight approaches for enhancing M2 cell-mediated nerve repair and regeneration.

关键词： nerve regeneration macrophage origin polarization function nerve injury nerve repair tissue engineering neural regeneration

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