检索结果-南通市图书馆

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING 2024年第9期18卷 106-0页

作者： gong, ziqin Li, Zengyong Zeng, Xu Yue, Fengxia Lan, Wu Liu, Chuanfu South China Univ Technol Sch Light Ind & Engn State Key Lab Pulp & Paper Engn Guangzhou 510640 Peoples R China Anhui Agr Univ Anhui Prov Engn Ctr High Performance Biobased Nylo Sch Mat & Chem Hefei 230036 Anhui Peoples R China

A significant reaction in the synthesis of biomass-based chemicals is the catalyst-based and targeted oxidation of monosaccharides into valuable sugar acids. In this study, an activated carbon supported gold catalyst was used to oxidize glucose and xylose to gluconic acid and xylonic acid under neutral condition. Optimization of reaction conditions for the catalysts was performed using both a batch reactor and a flow-through reactor. In a batch reactor, the yields of gluconic and xylonic acid reached 93% and 92%, respectively, at 90 degrees C within 180 min. In a flow reactor, both reactions reached a similar yield at 80 degrees C with the weight hourly space velocity of 47.1 h-1. The reaction kinetics were explored in the flow reactor. The oxidation of glucose and xylose to gluconic and xylonic acid followed a first-order kinetics and the turnover frequency was 0.195 and 0.161 s-1, respectively. The activation energy was evaluated to be 60.58 and 59.30 kJmol-1, respectively. This study presents an environmentally friendly and feasible method for the selective oxidation of monosaccharides using an activated carbon supported gold catalyst, benefiting the high-value application of carbohydrates.

关键词： monosaccharides oxidation gluconic acid xylonic acid flow reactor kinetics BASE-FREE OXIDATION SELECTIVE OXIDATION NIOBIUM PHOSPHATE AEROBIC OXIDATION GLUCONIC ACID DEFECT-RICH BIOMASS NANOPARTICLES PERFORMANCE DERIVATIVES

TGF-βsignaling in health,disease,and therapeutics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第4期9卷 1466-1505页

作者： ziqin Deng Tao Fan Chu Xiao He Tian Yujia Zheng Chunxiang Li Jie He Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

ransforming growth factor(TGF)-βis a multifunctional cytokine expressed by almost every tissue and cell *** signal transduction of TGF-βcan stimulate diverse cellular responses and is particularly critical to embryonic development,wound healing,tissue homeostasis,and immune homeostasis in *** dysfunction of TGF-βcan play key roles in many diseases,and numerous targeted therapies have been developed to rectify its pathogenic *** the past decades,a large number of studies on TGF-βsignaling have been carried out,covering a broad spectrum of topics in health,disease,and ***,a comprehensive overview of TGF-βsignaling is required for a general picture of the studies in this *** this review,we retrace the research history of TGF-βand introduce the molecular mechanisms regarding its biosynthesis,activation,and signal *** also provide deep insights into the functions of TGF-βsignaling in physiological conditions as well as in pathological ***-β-targeting therapies which have brought fresh hope to the treatment of relevant diseases are *** the summary of previous knowledge and recent updates,this review aims to provide a systematic understanding of TGF-βsignaling and to attract more attention and interest to this research area.

关键词： homeostasis healing wound

The stance and factors of international organizations towards countries from a Chinese perspective

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Data Intelligence 2024年第1期6卷 158-182页

作者： Qin Zhang Haili Xue Yaotian Wang Yao Wang ziqin Zhang Qinghua Qin Haoguang Liang National Science Library Chinese Academy of Sciences100190China China Center for Modernization Research 100190China Beijing International Studies University 100024China Beijing Key Laboratory of National Belt and Road Data Analysis and Decision Support 100024China University College London WC1E 6BTUK

The degree and scope of constraints imposed by International Organizations(IOs)on States are increasing,and identifying the factors affecting the IOs’stances on States is helpful to enhance the state's discourse power and influence in the international ***,by coding the records of Regular Press Conferences of the Speaking Office of the Chinese Ministry of Foreign Affairs during the period of 20182022,we obtained a dataset of IOs’stances on China-related ***,we constructed political relation,economic relation,and humanistic relation indicators to complement the influence factors,adopted the Bayesian logit model,and applied the Monte Carlo Markov chain algorithm and Gibbs sampling to analyze the probability of IOs’positive stances towards *** result shows that IOs’category,length of establishment,functional position,and relationship with China are all related to their tendency of making a statement about *** terms of the heterogeneity of event types,forum-type IOs are significantly inclined to give positive assessment compared to service-type IOs on events focusing on China's own *** analysis reveals that the model for analyzing and predicting the attitudes of IOs is more effective when the international situation is in a stable period.

关键词： Bayesian Logit Model IOs' stances Attitude analysis Monte Carlo Markov chain International relation indicator

3D printing encouraging desired in-situ polypyrrole seed-polymerization for ultra-high energy density supercapacitors

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第8期95卷 117-125,I0004页

作者： Tiantian Zhou Shangwen Ling Shuxian Sun Ruoxin Yuan ziqin Wu Mengyuan Fu Hanna He Xiaolong Li Chuhong Zhang State Key Laboratory of Polymer Materials Engineering Polymer Research InstituteSichuan UniversityChengdu 610065SichuanChina

The tireless pursuit of supercapacitors with high energy density entails the parallel advancement of wellsuited electrode materials and elaborately engineered ***(PPy)emerges as an exceedingly conductive polymer and a prospective pseudocapacitive materials for supercapacitors,yet the inferior cyclic stability and unpredictable polymerization patterns severely impede its real-world ***,for the first time,an innovative seed-induced in-situ polymerization assisted 3D printing strategy is proposed to fabricate PPy-reduced graphene oxide/poly(vinylidene difluoride-cohexafluoropropylene)(PVDF-HFP)(PPy-rGO/PH)electrodes with controllable polymerization behavior and exceptional areal mass *** preferred active sites uniformly pre-planted on the 3D-printed graphene substrates serve as reliable seeds to induce efficient polypyrrole deposition,achieving an impressive mass loading of 185.6 mg cm^(-2)(particularly 79.2 mg cm^(-2)for polypyrrole)and a superior areal capacitance of 25.2 F cm^(-2)at 2 mA cm^(-2)for a 12-layer *** agreement with theses appealing features,an unprecedented areal energy density of 1.47 mW h cm^(-2)for a symmetrical device is registered,a rarely achieved value for other PPy/rGO-based *** work highlights a promising route to preparing high energy density energy storage modules for real-world applications.

关键词： 3D printing Seed-induced polymerization Supercapacitor Polypyrrole High energy density

The underlying mechanism of variety–water–nitrogen–stubble damage interactions on yield formation in ratoon rice with low stubble height under mechanized harvesting

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第3期23卷 806-823页

作者： Jingnan Zou ziqin Pang Zhou Li Chunlin Guo Hongmei Lin Zheng Li Hongfei Chen Jinwen Huang Ting Chen Hailong Xu Bin Qin Puleng Letuma Weiwei Lin Wenxiong Lin College of Life Sciences Fujian Agriculture and Forestry University(FAFU)/Fujian Key Laboratory for Agroecological Processes and Safety MonitoringFuzhou 350002China College of Agriculture FAFU/Fujian Key Laboratory for Crop Physiology and Molecular EcologyFuzhou 350002China Institute of Oceanography College of Geography and OceanographyMinjiang UniversityFuzhou 350108China Crop Science Department The National University of LesothoRoma 00100Lesotho The Agricultural Extension Station of Pucheng County Nanping 353400China

Agronomic measures are the key to promote the sustainable development of ratoon rice by reducing the damage from mechanical crushing to the residual stubble of the main crop, thereby mitigating the impact on axillary bud sprouting and yield formation in ratoon rice. This study used widely recommended conventional rice Jiafuzhan and hybrid rice Yongyou 2640 as the test materials to conduct a four-factor block design field experiment in a greenhouse of the experimental farm of Fujian Agricultural and Forestry University, China from 2018 to *** treatments included fertilization and no fertilization, alternate wetting and drying irrigation and continuous water flooding irrigation, and plots with and without artificial crushing damage on the rice stubble. At the same time, a 13C stable isotope in-situ detection technology was used to fertilize the pot experiment. The results showed significant interactions among varieties, water management, nitrogen application and stubble *** to the long-term water flooding treatment, the treatment with sequential application of nitrogen fertilizer coupled with moderate field drought for root-vigor and tiller promotion before and after harvesting of the main crop, significantly improved the effective tillers from low position nodes. This in turn increased the effective panicles per plant and grains per panicle by reducing the influence of artificial crushing damage on rice stubble and achieving a high yield of the regenerated rice. Furthermore, the partitioning of 13C assimilates to the residual stubble and its axillary buds were significantly improved at the mature stage of the main crop, while the translocation rate to roots and rhizosphere soil was reduced at the later growth stage of ratooning season rice. This was triggered by the metabolism of hormones and polyamines at the stem base regulated by the interaction of water and fertilizer at this time. We therefore suggest that to achieve a high yield of ratoon rice

关键词： mechanized harvesting ratoon rice rice stubble yield attributes

Personalized surgical recommendations and quantitative therapeutic insights for patients with metastatic breast cancer: Insights from deep learning

在线全文

学校读者我要写书评

暂无评论

Cancer Innovation 2024年第3期3卷 65-80页

作者： Enzhao Zhu Linmei Zhang Jiayi Wang Chunyu Hu Qi Jing Weizhong Shi ziqin Xu Pu Ai Zhihao Dai Dan Shan Zisheng Ai School of Medicine Tongji UniversityShanghaiChina Shanghai Engineering Research Center of Tooth Restoration and Regeneration Research Institute of StomatologyStomatological Hospital and Dental School of Tongji UniversityShanghaiChina Tenth People's Hospital of Tongji University School of MedicineTongji UniversityShanghaiChina Department of Anesthesiology and Perioperative Medicine Shanghai Fourth People's HospitalSchool of MedicineTongji UniversityShanghaiChina Shanghai Hospital Development Center ShanghaiChina Columbia University New YorkNYUSA School of Medicine Royal College of Surgeons in IrelandUniversity of Medicine and Health SciencesDublinIreland Department of Biobehavioral Sciences Columbia UniversityNew YorkNYUSA Department of Medical Statistics School of MedicineTongji UniversityShanghaiChina Clinical Research Center for Mental Disorders Chinese-German Institute of Mental HealthShanghai Pudong New Area Mental Health CenterSchool of MedicineTongji UniversityShanghaiChina

Background:The role of surgery in metastatic breast cancer(MBC)is currently *** novel statistical and deep learning(DL)methods promise to infer the suitability of surgery at the individual ***:The objective of this study was to identify the most applicable DL model for determining patients with MBC who could benefit from surgery and the type of surgery ***:We introduced the deep survival regression with mixture effects(DSME),a semi-parametric DL model integrating three causal inference *** models were trained to make individualized treatment *** who received treatments in line with the DL models'recommendations were compared with those who underwent treatments divergent from the *** probability weighting(IPW)was used to minimize *** effects of various features on surgery selection were visualized and quantified using multivariate linear regression and causal ***:In total,5269 female patients with MBC were *** was an independent protective factor,outperforming other models in recommending surgery(IPW-adjusted hazard ratio[HR]=0.39,95%confidence interval[CI]:0.19–0.78)and type of surgery(IPW-adjusted HR=0.66,95%CI:0.48–0.93).DSME was superior to other models and traditional guidelines,suggesting a higher proportion of patients benefiting from surgery,especially breast-conserving *** debiased effect of patient characteristics,including age,tumor size,metastatic sites,lymph node status,and breast cancer subtypes,on surgery decision was also ***:Our findings suggested that DSME could effectively identify patients with MBC likely to benefit from surgery and the specific type of surgery *** method can facilitate the development of efficient,reliable treatment recommendation systems and provide quantifiable evidence for decision-making.

关键词： breast surgery causal inference deep learning metastatic breast cancer

面向执法效能提升的行政执法权下沉路径研究——以浙江省五个试点乡镇(街道)为样本

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国行政管理 2024年第6期40卷 47-58页

作者：方涧刘子琴浙江工商大学法学院浙江工商大学法治浙江建设研究院杭州310000

在深入推进综合行政执法改革的背景下,行政执法权下沉(乡镇、街道)是现阶段的改革重心。其本质在于权力的重新配置,从理论上讲,权力下沉能有效破解行政主体碎片化困境,确保事权分配的终局性,有助于优化行政权的配置与运行,浙江省的试点... 详细信息

在深入推进综合行政执法改革的背景下,行政执法权下沉(乡镇、街道)是现阶段的改革重心。其本质在于权力的重新配置,从理论上讲,权力下沉能有效破解行政主体碎片化困境,确保事权分配的终局性,有助于优化行政权的配置与运行,浙江省的试点改革印证了这一模式的有效性。然而,实践中依然存在下沉机制缺陷凸显、事权资源难以匹配、条块关系自我羁束等问题。为了克服上述问题,需要通过从结构上完善组织法,并坚持“整体政府”理念,构建差异化的权力下沉制度,健全执法人员编配管理机制,提升基层执法者专业素质,以数据信息平台整合碎片化治理层级等方式推动执法效能提升。

关键词：执法权下沉行政执法效能综合行政执法基层治理

在线全文

学校读者我要写书评

暂无评论

部分服务台同步多重休假的排队库存系统

运筹学学报（中英文） 2024年第1期28卷 40-56页

作者：叶子钦岳德权燕山大学理学院河北秦皇岛066004

本文研究了(s,S)库存策略的多服务台排队库存系统,其中库存为空时有部分服务台同步多重休假,休假时间服从指数分布。顾客到达为泊松过程,每个服务台的服务时间和补货时间均服从指数分布。利用拟生灭过程和矩阵几何解法,计算了系统稳态... 详细信息

本文研究了(s,S)库存策略的多服务台排队库存系统,其中库存为空时有部分服务台同步多重休假,休假时间服从指数分布。顾客到达为泊松过程,每个服务台的服务时间和补货时间均服从指数分布。利用拟生灭过程和矩阵几何解法,计算了系统稳态概率和一些性能指标,并给出了系统单位时间的平均费用函数。最后,通过数值算例分析了参数对费用函数的影响,并得到最优库存策略和最优平均费用。

关键词：排队库存系统部分服务台休假 (s,S)库存策略拟生灭过程矩阵几何解

在线全文

学校读者我要写书评

暂无评论

供应中断风险下竞争零售商的采购与定价决策

计算机集成制造系统 2024年第7期30卷 2553-2565页

作者：张雷王紫琴周学广浙江财经大学管理学院浙江杭州310018

针对由两个竞争供应商和两个竞争零售商组成的二级供应链,研究供应中断风险下企业的最优决策问题。考虑供应商的供应中断之间存在相关性以及零售商的响应定价,建立供应商定价、零售商决定采购量、零售商定价的三阶段博弈模型,得到供应... 详细信息

针对由两个竞争供应商和两个竞争零售商组成的二级供应链,研究供应中断风险下企业的最优决策问题。考虑供应商的供应中断之间存在相关性以及零售商的响应定价,建立供应商定价、零售商决定采购量、零售商定价的三阶段博弈模型,得到供应商和零售商各自的最优策略。研究发现:①虽然供应商之间相关性的增加削弱了双源采购的风险分散好处,但加剧了供应商之间的价格竞争,使得零售商的利润增加,因此零售商会选择相关性更高的两个供应商。②零售商之间的竞争越激烈,供应的可靠性越重要,于是零售商向可靠性更高的供应商采购更多的数量。③供应商提高其可靠性不仅有利于供应商自身,而且对零售商也有益。

关键词：供应中断双源采购响应型定价竞争零售商

在线全文

学校读者我要写书评

暂无评论

棉织物的低共熔溶剂退浆

印染 2021年第10期47卷 1-5页

作者：龚梓琴黄智豪徐华君刘文景余圆圆江南大学生态纺织教育部重点实验室江苏无锡214122 浙江灏宇科技有限公司浙江绍兴312369

针对传统退浆方法环境污染大的问题,利用生态环保的低共熔溶剂对棉织物进行退浆。复配了尿素-氯化胆碱(UC DES)和苹果酸-氯化胆碱(MC DES)两种低共熔溶剂,采用浸渍法对淀粉上浆的纯棉织物分别进行退浆。研究了处理时间、处理温度、坯布... 详细信息

针对传统退浆方法环境污染大的问题,利用生态环保的低共熔溶剂对棉织物进行退浆。复配了尿素-氯化胆碱(UC DES)和苹果酸-氯化胆碱(MC DES)两种低共熔溶剂,采用浸渍法对淀粉上浆的纯棉织物分别进行退浆。研究了处理时间、处理温度、坯布与溶剂的质量比、搅拌和热水浸渍预处理对退浆效果的影响。结果表明,采用MC DES退浆,处理温度105℃,坯布与MC DES的质量比1∶50,处理时间30 min,处理过程中加以搅拌,织物的退浆率达89.73%;采用UC DES退浆,处理温度85℃,坯布与UC DES的质量比1∶25,处理时间30 min,处理过程中加以搅拌,退浆率为90.68%。与传统碱退浆法相比,MC DES退浆织物的断裂强力下降较大,强力约为坯布的21%;UC DES退浆织物的断裂强力略有下降,并且高于碱退浆织物。DES退浆对织物的白度和毛效无明显影响。

关键词：退浆低共熔溶剂氯化胆碱苹果酸尿素棉织物