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Thermal lens analysis in a diode-pumped 10 Hz 100 mJ Yb:YAG amplifier

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High Power Laser Science and Engineering 2020年第2期8卷 24-31页

作者： Victor Hariton Celso Paiva Joao Hugo Pires Mario Galletti goncalo figueira GoLP/Instituto de Plasmas e Fusao Nuclear Instituto Superior TécnicoUniversidade de LisboaAv.Rovisco Pais1049-001 LisbonPortugal Central Laser Facility Science and Technology Facilities CouncilRutherford Appleton LaboratoryHarwell Science and Innovation CampusDidcot OX110QXUK

We address the power scaling issue in end-pumped laser rod amplifiers by studying,experimentally and numerically,the magnitude of thermal lensing in a high-energy diode-pumped Yb:YAG *** spatio-temporal temperature profile of the gain medium and the focal length of the induced thermal lens are determined *** influence of the repetition rate and pumping power on the temperature distribution is *** measurements covered repetition rates between 1 and 10 Hz and up to 4 kW pumping power.

关键词： diode-pumped lasers high-energy laser amplifiers thermal effects in lasers ytterbium-doped laser media

High efficiency second harmonic generation of nanojoule-level femtosecond pulses in the visible based on BiBO

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High Power Laser Science and Engineering 2019年第1期7卷 82-89页

作者： Mario Galletti Hugo Pires Victor Hariton Celso Paiva Joao Swen Künzel Marco Galimberti goncalo figueira GoLP/Instituto de Plasmas e Fusao Nuclear Instituto Superior Técnico Universidade de Lisboa Central Laser Facility Science and Technology Facilities Council Rutherford Appleton Laboratory Harwell Science and Innovation Campus

We demonstrate high efficiency second harmonic generation(SHG) of near infrared femtosecond pulses using a BiB3 O6 crystal in a single-pass tight focusing geometry setup. A frequency doubling efficiency of 63% is achieved, which is,to the best of our knowledge, the highest value ever reported in the femtosecond regime for such low energy(nJ-level)pumping pulses. Theoretical analyses of the pumping scheme focusing waist and the SHG efficiency are performed, by numerically solving the three wave mixing coupled equations in the plane-wave scenario and by running simulations with a commercial full 3 D code. Simulations show a good agreement with the experimental data regarding both the efficiency and the pulse spectral profile. The simulated SHG pulse temporal profile presents the characteristic features of the group velocity mismatch broadening in a ‘thick' crystal.

关键词： nonlinear process second harmonic generation pumping scheme parametric amplification/oscillators high power laser

Preliminary notes on brain weight variation across labrid fish species with different levels of cooperative behaviour

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Current Zoology 2015年第2期61卷 274-280页

作者： Marta C. SOARES goncalo I. ANDRE Jose R. PAULA CIBIO Centro de Investiga~ao em Biodiversidade e Recursos Gen6ticos Universidade do Porto Campus AgrS.rio de Vairao4485-661 Vair~o Portugal

Brain size and weight vary tremendously in the animal kingdom. It has been suggested that brain structural development must evolve balanced between the advantages of dealing with greater social challenges and the energetic costs of maintaining and developing larger brains. Here we ask if interspecific differences in cooperative behaviour (i.e. cleaning behaviour) are related to brain weight variations in four close-related species of Labrid fish: two are obligatory cleanerfish throughout their entire life (Labroides dimidiatusandL. bicolor), one facultative cleaner fishLabropsis australisand one last species that never engage in cleaningLabrichthys unilineatus. We first search for the link between the rate of species’ cooperation and its relative brain weight, and finally, if the degree of social complexity and cooperation are reflected in the weight of its major brain substructures. Overall, no differences were found in relative brain weight (in relation to body weight) across species. Fine-scale differences were solely demonstrated for the facultative cleanerL. australis, at the brainstem level. Furthermore, data visual examination indicates that the average cerebellum and brainstem weights appear to be larger forL. dimidiatus. Because variation was solely found at specific brain areas (such as cerebellum and brainstem) and not for the whole brain weight values, it suggests that species social-ecological and cognitive demands may be directly contributing to a selective investment in relevant brain areas. This study provides first preliminary evidence that links potential differences in cognitive ability in cooperative behaviour to how these may mediate the evolution of brain structural development in non-mammal vertebrate groups.

关键词：重量差异合作率大脑行为鱼种社会生态动物类群脑结构

Neutrophile-to-lymphocyte,lymphocyte-to-monocyte,and platelet-tolymphocyte ratios as prognostic and response biomarkers for resectable locally advanced gastric cancer

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World Journal of Gastrointestinal Oncology 2022年第7期14卷 1307-1323页

作者： Tiago Cruz Tomás Ines Eiriz Marina Vitorino Rodrigo Vicente Joao Gramaca Alicia Guadalupe Oliveira Paulo Luz Mafalda Baleiras Ana Sofia Spencer Luísa Leal Costa Patrícia Liu Joana Mendonca Magno Dinis Teresa Padrao Marisol Correia goncalo Atalaia Michelle Silva Teresa Fiúza Department of Medical Oncology Hospital Professor Doutor Fernando Fonseca EPEAmadora 2720-276Portugal Department of Medical Oncology Centro Hospitalar Barreiro-Montijo EPEBarreiro 2830-003Portugal Department of Medical Oncology Hospital do Espírito Santo deÉvora EPEÉvora 7000-811Portugal Department of Medical Oncology Centro Hospitalar Universitário do Algarve EPEAlgarve 8000-386Portugal Department of Medical Oncology Hospital São Francisco XavierCentro Hospitalar Lisboa Ocidental EPELisboa 1449-005Portugal Department of Medical Oncology Hospital Santo António dos CapuchosCentro Hospital Lisboa Central EPELisboa 1169-050Portugal Department of Medical Oncology Hospital BeatrizÂngeloLoures 2674-514Portugal Department of Medical Oncology Centro Hospitalar de Trás-os-Montes e Alto Douro EPEVila Real 5000-508Portugal Department of Medical Oncology Hospital da Senhora da Oliveira EPEGuimarães 4835-044Portugal Department of Medical Oncology Hospital Garcia de Orta EPEAlmada 2805-267Portugal Department of Medical Oncology Hospital da LuzLisboa 1500-650Portugal Department of Medical Oncology Hospital Distrital de Santarém EPESantarém 2005-177Portugal

BACKGROUND Perioperative fluorouracil plus leucovorin,oxaliplatin,and docetaxel(FLOT)improves prognosis in locally advanced gastric cancer(LAGC).Neutrophil-to-lymphocyte(NLR),lymphocyte-tomonocyte(LMR),and platelet-to-lymphocyte(PLR)ratios are prognostic biomarkers but not predictive *** To assess blood ratios’(NLR,LMR and PLR)potential predictive response to FLOT and survival outcomes in resectable LAGC *** This was a multicentric retrospective study investigating the clinical potential of NLR,LMR,and PLR in resectable LAGC patients,treated with at least one preoperative FLOT cycle,from 12 Portuguese *** were compared through non-parametric Mann-Whitney *** operating characteristic curve analysis defined the cut-off values as:High PLR>141 for progression and>144 for mortality;high LMR>3.56 for T stage regression(TSR).Poisson and Cox regression models the calculated relative risks/hazard ratios,using NLR,pathologic complete response,TSR,and tumor regression grade(TRG)as independent variables,and overall survival(OS)as the dependent *** This study included 295 patients(mean age,63.7 years;59.7% males).NLR was correlated with survival time(r=0.143,P=0.014).PLR was associated with systemic progression during FLOT(P=0.022)and mortality(P=0.013),with high PLR patients having a 2.2-times higher risk of progression[95% confidence interval(CI):0.89-5.26]and 1.5-times higher risk of mortality(95%CI:0.92-2.55).LMR was associated with TSR,and high LMR patients had a 1.4-times higher risk of achieving TSR(95%CI:1.01-1.99).OS benefit was found with TSR(P=0.015)and partial/complete TRG(P<0.001).Patients without TSR and with no evidence of pathological response had 2.1-times(95%CI:1.14-3.96)and 2.8-times(95%CI:1.6-5)higher risk of *** Higher NLR is correlated with longer survival *** LMR patients have a higher risk of decreasing T stage,whereas high PLR patients have higher odds of progressing under FLOT a

关键词： Gastric cancer Perioperative fluorouracil plus leucovorin,oxaliplatin,and docetaxel Neutrophil-to-lymphocyte Lymphocyte-to-monocyte Platelet-to-lymphocyte Tumor regression grade

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水产饲料中霉菌毒素的危害

饲料研究 2011年第11期34卷 75-76页

作者： Katia Pedrosa goncalo Santos 程宗佳(摘译) 美国大豆协会国际项目北京办事处北京市朝阳区建国门外大街1号国贸大厦2座904室100004 不详

近年来,几个因素导致鱼粉价格不断上涨,所以利用价格低廉的植物性蛋白原料替代鱼粉的趋势越来越明显,导致水产饲料被一种或多种类型霉菌毒素污染的风险也越来越高。更多的农作物被霉菌毒素污染的情况在动物性饲料行业是一个普遍存在的... 详细信息

近年来,几个因素导致鱼粉价格不断上涨,所以利用价格低廉的植物性蛋白原料替代鱼粉的趋势越来越明显,导致水产饲料被一种或多种类型霉菌毒素污染的风险也越来越高。更多的农作物被霉菌毒素污染的情况在动物性饲料行业是一个普遍存在的问题。

关键词：霉菌毒素污染水产饲料危害替代鱼粉蛋白原料饲料行业植物性动物性

Milroy Disease:A Case Report

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Case Reports in Clinical Medicine 2015年第11期4卷 349-351页

作者： goncalo Gomes Pereira Joana Moreira Vaz de Macedo Mário Santos General Practice Departement USF Sem FronteirasSanta Maria da FeiraPortugal General Practice Departement USF CoveloPortoPortugal

Hereditary lymphoedema type I is a congenital onset primary lymphoedema with autosomal dominant inheritance, which is characterized by the swelling of the lower body. In this article, the authors report a case of a 32-year-old woman with repeating episodes of swollen limbs. Imaging studies and genetic study were carried out and a Milroy’s syndrome diagnosis was established. The patient started sintomatic treatment of the edema, with fitting stockings and descompressive massage, with symptomatic benefit.

关键词： Milroy Disease Lower Limbs Edema FLT4 Gene VEGFR-3

Pseudoathletic Appearance:A Case Report in a Male

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Case Reports in Clinical Medicine 2015年第12期4卷 361-363页

作者： Joana Moreira goncalo Gomes Pereira Mário Santos Vaz de Macedo General Practice Department USF CoveloPortoPortugal General Practice Department USF Sem FronteirasSanta Maria da FeiraPortugal

Multiple Symmetric Lipomatosis (MSL) is a rare condition characterized by a symmetrical pattern of massive fatty deposits. This condition predominates in males, between 30 and 60 years. In this article, the authors present a case report of a 47-year-old man that resorted to consultation to perform routine medical exams, without any complaint associated. Physical examination shows multiple bilateral swellings in the proximal region of the upper limbs and analytically presents hyperuricemia, hypertriglyceridemia, hypercholesterolemia and changes in hepatic tests. CT revealed the presence of non-encapsulated homogeneous masses of adipose tissue in the proximal region of the limbs. Currently the patient is asymptomatic, being monitoring in consultation.

关键词： Symmetric Multiple Lipomatosis Hyperuricemia Hypertriglyceridemia Hypercholesterolemia

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松林美宅

现代装饰（家居） 2011年第1期 88-91页

作者： goncalo de Sousa Bandeira 肖俊 Salazar de Sousa

这是个位于葡萄牙辛特拉的住宅项目,该项目地处景色怡人的松林中的一部分,地理位置十分优越,松林一直延伸至人的肉眼所及之处,住户还可观赏到远处辛特拉山脉的全景。根据屋主的要求,希望在这块面积为6700m^2、地势倾斜的建筑用地上建造... 详细信息

这是个位于葡萄牙辛特拉的住宅项目,该项目地处景色怡人的松林中的一部分,地理位置十分优越,松林一直延伸至人的肉眼所及之处,住户还可观赏到远处辛特拉山脉的全景。根据屋主的要求,希望在这块面积为6700m^2、地势倾斜的建筑用地上建造两套住房,其中一套供父母居住,而另一套供孩子们居住。在不改变建筑结构的常规之下,这两套住宅各具特色,同时,在既定的空间规划中还包括围绕两套住宅所建造的花园。然而原本向上抬升的地形也给设计师进行地形转换带来了挑战,为设计师最终创造出一种全新的户外体验形式创造机遇。

关键词：辛特拉空间规划建筑结构景色怡人私密性 garden 形式创造建筑用地 Panoram 屋顶

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沙漠中的时尚生活

现代装饰（家居） 2012年第12期 86-95页

作者： goncalo Salazar de Sousa Joao Morgado 肖俊葡萄牙Gonalo Salazar de Sousa Arquitectos

这是一幢位于葡萄牙海滨旅游区Comporta的度假屋。房屋所在地是一个靠近大海的稻田保护区,这里到处可见当地人建造的小型建筑,它们多数风格简单,用金属、纤维水泥或茅草覆盖屋顶。由于现在度假屋的建造以之前的建筑为基础,因此建筑设计... 详细信息

这是一幢位于葡萄牙海滨旅游区Comporta的度假屋。房屋所在地是一个靠近大海的稻田保护区,这里到处可见当地人建造的小型建筑,它们多数风格简单,用金属、纤维水泥或茅草覆盖屋顶。由于现在度假屋的建造以之前的建筑为基础,因此建筑设计师们必须尊重原有的建筑区域和施工场地。考虑到原有建筑粗劣的工程质量,同时根据业主提供的新方案,设计师们决定彻底拆毁原有建筑。

关键词：原有建筑建筑设计师工程质量海滨旅游功能空间纤维水泥时尚生活小型建筑施工场地环氧树脂涂料