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Karydaki.瓣手术中常规窦腔引流是否必要:一项前瞻性、随机研究结果

世界核心医学期刊文摘（胃肠病学分册） 2006年第1期2卷 23-24页

作者： Gurer A. gomceli i. Ozdogan M. 尹勇 Mertler sok. 41/7 Bestepe 06510 Ankara TurkeyDr.

Di.ferent surgi.al techni.ues for pi.oni.al di.ease have been descri.ed i. the li.erature. i. thi. study our ai. was to evaluate the i.fluence of routi.e cavi.y drai.age i. the Karydaki. flap techni.ue. METHODS: Fi.ty pati.nts wi.h pi.oni.al si.us who underwent the Karydaki. flap operati.n were evaluated prospecti.ely. The pati.nts were assi.ned randomly i.to two groups - wi.h and wi.hout sucti.n drai.age of the cavi.y - and the effects of drai.s were studi.d i. terms of wound compli.ati.ns, hospi.al stay, and recurrence rate. RESULTS: There was no si.ni.i.ant di.ference between groups i. term of length of hospi.al stay. Compli.ati.n rate was 20 percent and the compli.ati.ns were caused exclusi.ely by flui. collecti.ns. Wound i.fecti.n, dehi.cence, or fai.ure was not observed i. any of the pati.nts. There has been no recurrence i. any of the pati.nts duri.g the follow- up peri.d. There was a si.ni.i.ant i.crease i. the number of flui. collecti.ns i. patents wi.hout a sucti.n drai.. CONCLUSi.N: The present study i.di.ates that routi.e cavi.y drai.age reduces the i.ci.ence of flui. collecti.n after the Karydaki. flap operati.n.

关键词：瓣手术 Karydaki. 随机研究骶尾窦抽吸引流切口并发症切口裂开复发率外科术后窦

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Gastri. carci.ogenesi.

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World Journal of Gastroenterology 2012年第37期18卷 5164-5170页

作者： i.mai. gomceli Bari. Demi.i. Mesut Tez Department of Gastroenterologi. Surgery Antalya Education and Research Hospital Department of General Surgery Ankara Numune Education and Research Hospital

Gastri. cancer i. the second most common cancer worldwi.e and the second most common cause of cancer-related deaths. Despi.e complete resecti.n of gastri. cancer and lymph node di.secti.n, as well as i.provements i. chemotherapy and radi.therapy, there are sti.l 700 000 gastri. cancer-related deaths per year worldwi.e and more than 80% of pati.nts wi.h advanced gastri. cancer di. of the di.ease or recurrent di.ease wi.hi. 1 year after di.gnosi.. None of the treatment modali.i.s we have been applyi.g today can i.fluence the overall survi.al rates:at present, the overall 5-year relati.e survi.al rate for gastri. cancer i. about 28%. Cellular metaplasi. due to chroni. i.flammati.n, i.jury and repai. are the most documented processes for neoplasi.. i. appears that chroni. i.flammati.n sti.ulates tumor development and plays a cri.i.al role i. i.i.i.ti.g, sustai.i.g and advanci.g tumor growth. i. i. also evi.ent that not all i.flammati.n i. tumori.eni.. Addi.i.nal mutati.ns can be acqui.ed, and thi. leads to the cancer cell gai.i.g a further growth advantage and acqui.i.g a more mali.nant phenotype. i.testi.ali.ati.n of gastri. uni.s, whi.h i. called "i.testi.al metaplasi."; phenotypi. antrali.ati.n of fundi. uni.s, whi.h i. called "spasmolyti. polypepti.e-expressi.g metaplasi."; and the development di.ectly from the stem/progeni.or cellzone are three pathways that have been descri.ed for gastri. carci.ogenesi.. Also, an i.portant factor for the development of gastroi.testi.al cancers i. peri.umoral stroma. However, the i.i.i.ti.g cellular event i. gastri. metaplasi. i. sti.l controversi.l. Understandi.g gastri. carci.ogenesi. and i.s precursor lesi.ns has been under i.tense i.vesti.ati.n, and our paper attempts to hi.hli.ht recent progress i. thi. fi.ld of cancer research.

关键词： Gastri. Cancer Cancer Stem Cell Carci.o-genesi. Oncogenesi. Tumori.enesi.

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