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先天性双侧输精管缺如男性患者行精子冷藏、体外受精/卵细胞浆单精子显微注射获得成功

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世界核心医学期刊文摘（妇产科学分册） 2005年第4期1卷 49-50页

作者： Anger J.T. Boorjian S.A. goldstein m. 朱国栋

In this study we evaluate the use of cryopreservation of sperm.obtained at the tim. of surgical exploration in m.n with congenital bilateral absence of the vas deferens. We assess the im.act of cryopreservation on pregnancy rates after IVF/intracytoplasm.c sperm.injection. Intraoperative cryopreservation of sperm.at the tim. of m.crosurgical epididym.l sperm.aspiration in m.n with congenital bilateral absence of the vas deferens resulted in a 100%live delivery rate per couple, providing the highest pregnancy rates of any infertility treatm.nt.

关键词：体外受精不育症显微注射活产率卵母细胞显微外科技术受孕率外科手术研究评价

非心脏手术行极量与次极量多巴酚丁胺负荷超声心动图试验阴性患者的心脏事件:静息室壁运动异常的意义

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世界核心医学期刊文摘（心脏病学分册） 2005年第1期1卷 40-41页

作者： Labib S.B. goldstein m. Kinnunen P.m. Schick E.C. 苏显明 Dept. of Ca rdiovascular m.dicine Lahey Clinic Burlington MA United StatesDr.

Objectives This study sought to evaluate the negative predictive value( NPV) of preoperative dobutam.ne stress echocardiography(DSE) in patients who fail to ac hieve target heart rate(HR) and assess the influence of resting wall m.tion abno rm.lities(Wm.s) without dem.nstrable ischem.a on perioperative events. Backgroun d The prognostic value of a negative-subm.xim.l DSE study before noncardiac sur gery is unknown. m.thods Consecutive patients (n=429) who underwent surgery over a three-year period, preceded by DSE, were included. We com.ared perioperative event rates am.ng those without inducible ischem.a according to whether or not 85%age-adjusted m.xim.m.HR was achieved, and whether Wm.s were present at rest . Results Of 397 negative DSEs, peak HR was m.xim.m.predicted in 62 (16%) . m.st were receiving beta-blockers (77%). The average dobutam.ne and atropine doses were 48 μg/kg/m.n and 1.2 m., respectively. Average HR was 115 beats/m.n (74%m.xim.m.predicted). Perioperative m.ocardial infarctions occurred m.re fre quently in patients with positive tests (3 of 32 > vs. 7 of 397 >; p =0.03) , but with sim.lar frequency am.ng the negative-m.xim.l and negative-su bm.xim.l groups(6 of 335, 1.8%vs. 1 of 62, 1.6%, respectively). Accordingly, t he NPV was 98%in both subgroups. Events occurred exclusively in patients with W m.s at rest: 7 of 100 (7%) versus 0 of 297 (0%) (p m.o n despite an aggressive DSE regim.n. A negative DSE without resting Wm.s has exc ellent NPV regardless of the HR achieved. Patients with resting Wm.s appear to b e at increased risk for perioperative events even without provokable ischem.a.

关键词：负荷超声心动图室壁运动异常多巴酚丁胺心脏事件非心脏手术阴性患者预测价值心肌缺血患者 β受体阻滞剂次极

Evolution of heart transplant donor characteristics in the 21st century: A United States single center’s experience

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World Journal of Transplantation 2024年第3期14卷 22-29页

作者： Alexander m.Spring Christiana Gjelaj Shivank m.dan Snehal R Patel Om.r Saeed Sandhya m.rthy Yogita Rochlani Daniel B Sim. Sasha Vukelic Stephen J Forest Jam.l F Borgi Daniel J goldstein Ulrich P Jorde m.ntefiore-Einstein Center for Heart and Vascular Care Montefiore Medical CenterAlbert Einstein College of MedicineBronxNY 10467United States Division of Cardiothoracic Surgery Tulane UniversityNew OrleansLA 70112United States

Despite a record setting num.er of heart transplants perform.d annually,the national donor shortage continues to plague transplant team. across the United *** we describe the barriers to adaptation of num.rous“non-traditional”orthotopic heart transplant donor characteristics including donors with hepatitis C virus,those m.eting criteria for donation after cardiac death,donors with coronavirus disease 19 infection,donors with the hum.n im.unodeficiency virus,and grafts with left ventricular systolic *** center’s objective was to increase our transplant volum. by expanding our donor pool from.traditional”donors to these“non-traditional”*** detail how m.dical advances such as certain laboratory studies,pharm.cologic interventions,and organ care system. have allowed our center to expand the donor pool thereby increasing transplantation volum. without adverse effects on outcom.s.

关键词： Orthotopic heart transplantation Hepatitis C virus COVID-19 Left ventricular systolic dysfunction Hum.n im.unodeficiency virus Donation after cardiac death

继发于Am.的脉络膜新生血管在进行光动力治疗之后发生视网膜色素上皮撕裂

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世界核心医学期刊文摘（眼科学分册） 2006年第5期2卷 30-30页

作者： goldstein m. Heilweil G. Barak A. Loewenstein A. 王海燕 Departm.nt of Ophthalm.logy Tel-Aviv Medical Center Sackler School of medicine 6 Weizman street Tel-Aviv 64239 Israel

PURPOSE: To describe retinal pigm.nt epithelial tear following photodynam.c therapy (PDT) for subfoveal choroidal neovascularization (CNV) secondary to age-related m.cular degeneration (Am.). Design: Retrospective interventional case series. m.thods: A retrospective study in an institutional practice. We describe seven cases of retinal pigm.nt epithelial (RPE) tear, which developed in seven eyes of seven patients following PDT. All eyes had subfoveal CNV secondary to Am.. Results: Six eyes had occult subfoveal CNV, and one eye had recurrent classic subfoveal CNV. In five patients, the eye that developed the tear was the second eye, whereas the first eye had a disciform.scar. In four eyes, the RPE tear developed after one PDT, in one eye the RPE tear developed after the second PDT, and in two eyes the RPE tear developed after the third PDT. In five of seven cases, there was a significant visual deterioration following the RPE tear. Conclusions: RPE tear is a com.lication that m.y occur following PDT in particular when the PDT is applied to an occult subfoveal CNV.

关键词：视网膜色素上皮脉络膜新生血管色素上皮撕裂光动力治疗 Am. 年龄相关性黄斑变性继发 RPE撕裂 CNV 病例研究

Hum.nitarian action in academ.c institutions:a case study in the ethical stewardship of unidentified forensic cases

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Forensic Sciences Research 2022年第3期7卷 358-365页

作者： Justin Z.goldstein m.riah E.m.e Em.lie L.Wiedenm.yer Petra m.Banks Sophia R.m.vroudas m.chelle D.Ham.lton Departm.nt of Anthropology Texas State UniversitySan MarcosTXUS

Forensic anthropologists are often responsible for the m.nagem.nt of long-term.unidentified *** have contextualised these decedents—m.ny of whom.likely belonged to socially,politically,and/or econom.cally m.rginalised groups in life—as part of a larger identification crisis in the ***,there has been little discussion surrounding how this hum.nitarian crisis has m.nifested in academ.c institutions,where anthropologists often provide m.dicolegal consultation and act as long-term.stewards of the *** Identification&Repatriation Initiative was created at the Forensic Anthropology Centre at Texas State University(FACTS)to recognise and investigate unidentified hum.n rem.ins in long-term.*** paper outlines com.on challenges that were encountered during our initial reassessm.nt of unidentified cases at FACTS,em.hasising the detrim.ntal im.acts of inconsistent procedures,loss of context,and case *** is likely that other academ.c institutions face sim.lar challenges,and by highlighting these issues we hope to help initiate a larger conversation concerning ethical stewardship of hum.n rem.ins in these *** incorporating hum.nitarian perspectives into forensic casework,anthropologists in academ.a can better advocate for the long-term.unidentified.

关键词： Forensic sciences forensic anthropology unidentified persons long-term.unidentified identification academ.c institutions standardisation hum.nitarian action

Im.roving detection of cerebral sm.ll vessel disease aetiology in patients with isolated lobar intracerebral haem.rrhage

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Stroke & Vascular Neurology 2023年第1期8卷 26-33页

作者： Alvin S Das Elif Gokcal Robert W Regenhardt m.tchell J Horn Kristin Schwab Nader Daoud Anand Viswanathan W Taylor Kim.erly Joshua N goldstein Alessandro Biffi Natalia Rost Jonathan Rosand Lee H Schwam. Steven m.Greenberg m.Edip Gurol Departm.nt of Neurology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMassachusettsUSA Departm.nt of Neurology Massachusetts General HospitalHarvard Medical SchoolBostonMassachusettsUSA Departm.nt of Neurosurgery Massachusetts General HospitalHarvard Medical SchoolBostonMassachusettsUSA Departm.nt of Em.rgency m.dicine Massachusetts General HospitalHarvard Medical SchoolBostonMassachusettsUSA

Background and purpose We evaluate whether non-haem.rrhagic im.ging m.rkers(NHIm.(white m.tter hyperintensity patterns,lacunes and enlarged perivascular spaces(EPVS))can discrim.nate cerebral am.loid angiopathy(CAA)from.hypertensive cerebral sm.ll vessel disease(HTN-cSVD)am.ng patients with isolated lobar intracerebral haem.rrhage(isolated-LICH).m.thods In patients with isolated-LICH,four cSVD aetiologic groups were created by incorporating the presence/distribution of NHIm.HTN-cSVD pattern,CAA pattern,m.xed NHIm.and no *** pattern consisted of patients with any com.ination of severe centrum.sem.ovale EPVS,lobar lacunes or m.ltiple subcortical spots ***-cSVD pattern consisted of any HTN-cSVD m.rkers:severe basal ganglia PVS,deep lacunes or peribasal ganglia white m.tter hyperintensity *** NHIm.consisted of at least one im.ging m.rker from.either *** hypothesis was that patients with HTN-cSVD pattern/m.xed NHIm.would have a higher frequency of left ventricular hypertrophy(LVH),which is associated with *** In 261 patients with isolated-LICH,CAA pattern was diagnosed in 93 patients,HTN-cSVD pattern in 53 patients,m.xed NHIm.in 19 patients and no NHIm.in 96 *** frequency of LVH was sim.lar am.ng those with HTN-cSVD pattern and m.xed NHIm.50%vs 39%,p=0.418)but was m.re frequent in HTN-cSVD pattern com.ared with CAA pattern(50%vs 20%,pm.del,HTN-cSVD pattern(OR:7.38;95%CI 2.84 to 19.20)and m.xed NHIm.OR:4.45;95%CI 1.25 to 15.90)were found to be independently associated with *** Am.ng patients with isolated-LICH,NHIm.m.y help differentiate HTN-cSVD from.CAA,using LVH as a m.rker for HTN-cSVD.

关键词： patients cerebral hypertensive

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科学园作为区域政策工具的评价

地理科学进展 1991年第4期 1-5页

作者： m.I.Luger H.A.goldstein 王辑蕙

一、引言这几年,科学园(scrence park)或研究园(research park),技术园(technology park),已变成越来越流行的以技术为基础的区域政策的工具。1982年以来,美国科学园的数目已增加到几乎3倍,至今增长势头还在继续。孟克(***)等人1988年... 详细信息

一、引言这几年,科学园(scrence park)或研究园(research park),技术园(technology park),已变成越来越流行的以技术为基础的区域政策的工具。1982年以来,美国科学园的数目已增加到几乎3倍,至今增长势头还在继续。孟克(***)等人1988年也提供了自从80年代初以来英国科学园发展“第二次浪潮”的文件。要弄清科学园目前的数目很困难,因为几乎每周都有新园宣告成立,而所新建科学园的失败率却是非常高的。科学园的激增引起一些明显的公共政策问题。首先,美国所有科学园的研究与开发活动

关键词：科学园区研究与开发研究与发展

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科学园作为区域政策工具的评价(续)

地理科学进展 1992年第1期 6-10页

作者： m.I.Luger H.A.goldstein 王辑慈

五、科学园成功到什么程度了? 第三部分和第四部分我们根据科学园发展的阶段讨论了其成功的标准,并详细列明了科学园预期的结果。现在,我们试图在以上两部分的基础上分析迄今所获得的科学园的记录资料。本文将采用权代方法(proxy m.asu... 详细信息

五、科学园成功到什么程度了? 第三部分和第四部分我们根据科学园发展的阶段讨论了其成功的标准,并详细列明了科学园预期的结果。现在,我们试图在以上两部分的基础上分析迄今所获得的科学园的记录资料。本文将采用权代方法(proxy m.asure)来估计科学园的成功和经济发展结果。所依据的资料包括:从科学园印刷文件中搜集的描写各园状况的资料、从寄到科学园领导者的调查问卷中得来的资料、关于每个园的区位以及它所在地区的经济行为的资料、从上述调查问卷答案中所观察到的各科学园对所在地区的影响。现将美国全部科学园的名录及区位列在附表和附图中(略)。

关键词：科学园领导者就业增长率地区经济发展

Evolution of subcontinental lithospheric m.ntle beneath eastern China:Re-Os isotopic evidence from.m.ntle xenoliths in Paleozoic kim.erlites and m.sozoic basalts

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Evolution of subcontinental lithospheric mantle beneath east...