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妊娠期及产后血栓形成

世界核心医学期刊文摘（妇产科学分册） 2005年第11期1卷 11-12页

作者： James A.H. Tapson V.F. goldhaber s.z. 朱晓明 Box 3967 Duke University Medical Center Durham NC 27710 United States Dr.

Objective: To describe the circumstances surrounding deep vein thrombosis among pregnant or postpartum patients enrolled in a large multicenter registry. study design: Consecutive patients with ultrasound-confirmed deep vein thrombosis were enrolled at 183 institutions during a 6-month period from October 2001 to March 2002. Fifty-three who were either pregnant or within 6 weeks postpartum were analyzed. Results: Thirty-four were pregnant and 19 were postpartum. Among those pregnant, 44% experienced deep vein thrombosis in the first trimester, 24% in the second, and 26% in the third. Deep vein thrombosis occurred in the left lower extremity in 76% of the pregnant and 47% of the postpartum women. Four pregnant and 2 postpartum women had pelvic vein thrombosis. Among those postpartum, 74% had undergone surgery within 3 months. Conclusion: During pregnancy, the risk of deep vein thrombosis begins in the first trimester. Thus, we believe that when prophylaxis is indicated, it should be initiated early in gestation.

关键词：产后血栓形成妊娠晚期深部静脉血栓妊娠早期深静脉血栓形成发生者周围环境超声检查预防措施研究设计

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大面积肺动脉栓塞

世界核心医学期刊文摘（心脏病学分册） 2006年第7期2卷 24-25页

作者： Kucher N. Rossi E. De Rosa M. goldhaber s.z. 郭俊 Cardiovascular Division Brigham and Women's Hospital 75 Francis St Boston MA 02115 United States Dr.

Background -Acute massive pulmonary embolism(PE) carries an exceptionally high mortality rate. We explored how often adjunctive therapies, particularly thrombolysis and inferior vena caval(IVC) filter placement, were performed and how these therapies affected the clinical outcome of patients with massive PE. Methods and Results -Among 2392 patients with acute PE and known systolic arterial blood pressure at presentation, from the International Cooperative Pulmonary Embolism Registry(ICOPER), 108(4.5%) had massive PE, defined as a systolic arterial pressuressive PE with a systolic arterial pressure ≥90 mm Hg. PE was first diagnosed at autopsy in 16 patients(15%) with massive PE and in 29 patients(1%) with non-massive PE(Ps were 52.4%(95%CI, 43.3%to 62.1%) and 14.7%(95%CI, 13.3%to 16.2%), respectively. In-hospital bleeding complications occurred in 17.6%versus 9.7%and recurrent PE within 90 days in 12.6%and 7.6%, respectively(Ps with massive PE, thrombolysis, surgical embolectomy, or catheter embolectomy were withheld in 73(68%). Thrombolysis was performed in 33 patients, surgical embolectomy in 3, and catheter embolectomy in 1. Thrombolytic therapy did not reduce 90-day mortality(thrombolysis, 46.3%; 95%CI, 31.0%to 64.8%; no thrombolysis, 55.1%; 95%CI, 44.3%to 66.7%; hazard ratio, 0.79; 95%CI, 0.44 to 1.43). Recurrent PE rates at 90 days were similar in patients with and without thrombolytic therapy(12%for both; P=0.99). None of the 11 patients who received an IVC filter developed recurrent PE within 90 days, and 10(90.9%) survived at least 90 days. IVC filters were associated with a reduction in 90-day mortality(hazard ratio, 0.12; 95%CI, 0.02 to 0.85). Conclusions -In ICOPER, two thirds of the patients with massive PE did not receive thrombolysis or embolectomy. Counterintuitively, thrombolysis did not reduce mortality or recurrent PE at 90 days. The observed reduction in m

关键词：肺动脉栓塞动脉收缩压肺栓塞临床结局切除术过滤装置出血并发症下腔静脉中所

592例上肢深静脉血栓形成患者的前瞻性登记研究

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世界核心医学期刊文摘（心脏病学分册） 2005年第2期1卷 26-27页

作者： Joffe H.V. Kucher N. Tapson V.F. goldhaber s.z. 梁磊 Department of Medicine Brigham and Women’s Hospital Har vard Medical School 75 Francis St Boston MA 02115 United States Dr.

Background Upper extremity deep vein thrombosis (UEDVT) occurs spontaneously or sometimes develops as a complication of pacemaker use, long term use of a c entral venous catheter (CVC), or cancer. Methods and Results To improve our und erstanding of UEDVT, we compared the demographics, symptoms, risk factors, proph ylaxis, and initial management of 324 (6%) patients with central venous cathete r (CVC) associated UEDVT, 268 (5%) patients with non CVC associated UEDVT, a nd 4796 (89%) patients with lower extremity DVT from a prospective Us multicen ter DVT registry. The non CVC associated UEDVT patients were younger (59.2±18 .2 versus 64.2±16.9 years old; Pss often white (65%versus 73%; P ss index [BMI] 26.8±7.1 versus 28.5±7.3 kg/m2; Psmoke (19%versus 13%; P=0.02) than the lower extremity DVT patients. By way of propensity analysis and multivariable logistic regressi on analysis, we determined that an indwelling CVC was the strongest independent predictor of UEDVT (odds ratio [OR], 7.3; 95%confidence interval [CI], 5.8 to 9 .2). An age ofs, a BMI ofspitalization were the inde pendent predictors of non CVC associated UEDVT. Most(68%) UEDVT patients were evaluated while they were inpatients. Only 20%of the 378 UEDVT patients who di d not have an obvious contraindication to anticoag ulation received prophylaxis at the time of diagnosis. Conclusions UEDVT risk factors differ from the conventional risk factors for lower extremity DVT. Our findings identify deficiencies in our current understanding and the prophylaxis of UEDVT and generate hypotheses for future research efforts.

关键词：上肢深静脉血栓形成传统危险因素静脉导管预防性治疗人口统计学禁忌证

Dynamics of a rotating ring-stiffened sandwich conical shell with an auxetic honeycomb core

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Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 963-982页

作者： s.JAHANGIRI A.GHORBANPOUR ARANI z.KHODDAMI MARAGHI Department of solid Mechanics Faculty of Mechanical EngineeringUniversity of KashanKashan ***Iran Faculty of Engineering Mahallat Institute of Higher EducationMahallat ***Iran

The free vibration analysis of a rotating sandwich conical shell with a reentrant auxetic honeycomb core and homogenous isotropic face layers reinforced with a ring support is *** shell is modeled utilizing the first-order shear deformation theory(FsDT)incorporating the relative,centripetal,and Coriolis accelerations alongside the initial hoop tension created by the *** governing equations,compatibility conditions,and boundary conditions are attained using Hamilton’s *** trigonometric functions,an analytical solution is derived in the circumferential direction,and a numerical one is presented in the meridional direction via the differential quadrature method(DQM).The effects of various factors on the critical rotational speeds and forward and backward frequencies of the shell are *** present work is the first theoretical work regarding the dynamic analysis of a rotating sandwich conical shell with an auxetic honeycomb core strengthened with a ring support.

关键词： free vibration conical shell rotating shell ring support auxetic honeycomb

Probing the Bardeen-Kiselev black hole with the cosmological constant caused by Einstein equations coupled with nonlinear electrodynamics using quasinormal modes and greybody bounds

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Communications in Theoretical Physics 2024年第6期76卷 102-119页

作者： s R Wu B Q Wang z W Long College of Physics Guizhou UniversityGuiyang 550025China College Pharmacy Guizhou University of Traditional Chinese MedicineGuiyang 550025China

In this work,we investigate a static and spherically symmetric Bardeen-Kiselev black hole(BH)with the cosmological constant,which is a solution of the Einstein-non-linear Maxwell field *** compute the quasinormal frequencies for the Bardeen-Kiselev BH with the cosmological constant due to electromagnetic and gravitational *** varying the BH parameters,we discuss the behavior of both real and imaginary parts of the BH quasinormal frequencies and compare these frequencies with the Reissner-Nordström-de sitter BH surrounded by quintessence(RN-dsQ).Interestingly,it is shown that the responses of the Bardeen-Kiselev BH with the cosmological constant and the RN-dsQ under electromagnetic perturbations are different when the charge parameter q,the state parameter w and the normalization factor c are varied;however,for the gravitational perturbations,the responses of the Bardeen-Kiselev BH with the cosmological constant and the RN-dsQ are different only when the charge parameter q is ***,compared with the gravitational perturbations,the electromagnetic perturbations can be used to understand nonlinear and linear electromagnetic fields in curved spacetime *** interesting observation is that,due to the presence of Kiselev quintessence,the electromagnetic perturbations around the Bardeen-Kiselev BH with the cosmological constant damps faster and oscillates slowly;for the gravitational perturbations,the quasinormal mode decays slowly and oscillates *** also study the reflection and transmission coefficients along with the absorption cross section in the Bardeen-Kiselev BH with the cosmological constant;it is shown that the transmission coefficients will increase due to the presence of Kiselev quintessence.

关键词： quasinormal modes greybody factors Bardeen-Kiselev black hole with cosmological constant

Construction of 2D/2D Ti_(3)C_(2)T_(x)MXene/Cds heterojunction with photothermal effect for efficient photocatalytic hydrogen production

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Journal of Materials science & Technology 2024年第4期171卷 1-9页

作者： T.Y.Huang z.Yang s.Y.Yang z.H.Dai Y.J.Liu J.H.Liao G.Y.zhong z.J.Xie Y.P.Fang s.s.z.ang Key Laboratory for Biobased Materials and Energy of Ministry of Education Guangdong Laboratory for Lingnan Modern AgricultureCollege of Materials and EnergySouth China Agricultural UniversityGuangzhou 510643China school of Physics and Optoelectronics South China University of TechnologyGuangzhou 510640China school of Chemical Engineering and Energy Technology Guangdong Provincial Key Laboratory of Distributed Energy SystemsDongguan University of TechnologyDongguan 523808China

The insensitivity of semiconductors to visible and infrared light is a key constraint on the utilization of light energy in photocatalytic *** photocatalysts with full-spectrum absorption through surface engineering is an effective approach to fully harnessing light energy in semiconductor ***,a novel stable Ti_(3)C_(2)T_(x)MXene/Cds heterojunction catalyst is obtained by in-situ epitaxial growth of two-dimensional(2D)Cds nanosheets on 2D MXene interface via a solvothermal *** exceptional light absorption properties of MXene confer outstanding full-spectrum driven photocat-alytic hydrogen evolution capability upon the heterogeneous *** unique 2D/2D structure effectively mitigated the recombination of photogenerated carriers,enhancing the photocatalytic performance of the ***,the composite catalyst exhibits a significantly higher surface temperature of 80.4℃under visible light irradiation at an intensity of 0.1 W/cm^(2),which is 1.84 times higher than that of *** irradiation of visible and near infrared light,the composite catalyst with photothermal ef-fect demonstrates a remarkable hydrogen evolution rate of 65.4 mmol g^(-1)h^(-1),which is 7.2 times higher than that of Cds *** study introduces a novel approach for constructing full-spectrum absorption catalysts and expands the application of the photothermal effect in photocatalytic hydrogen evolution research.

关键词： Two-dimensional structure Heterostructure Photothermal effect Photocatalyst Hydrogen evolution

Four Late-type Galaxies with Double Radio Lobes and Properties of such Galaxies

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Research in Astronomy and Astrophysics 2024年第4期24卷 84-90页

作者： z.s.Yuan X.Y.Gao z.L.Wen J.L.Han National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China CAs Key Laboratory of FAsT National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China school of Astronomy and space sciences University of Chinese Academy of SciencesBeijing 100049China

The triggering mechanism for radio lobes from late-type galaxies is not fully *** samples are desired for a thorough investigation and *** utilizing the optical data from the newly released Dark Energy spectroscopic Instrument imaging surveys and the radio sources from the NRAO VLA sky survey and the Faint Images of the Radio sky at Twenty-centimeter,we identify four Late-type Galaxies with double Radio Lobes(La GRLs):J0217-3645,J0947+6220,J1412+3723 and J1736+*** previously known La GRLs,we confirm the correlation between radio power P_(1.4GHz)and stellar mass M_(*)of host ***(25/35)La GRLs belong to the blue cloud galaxies,while the newly identified cases in this work are located within the region of the red *** find a clear correlation between the differential radio power,i.e.,the offset from the P_(1.4GHz)-M_(*)relation,and the galaxy color,indicating that bluer galaxies at a fixed M_(*)tend to host more powerful radio ***,the majority(31/36)of La GRLs are either located in a galaxy group or displaying a disturbed *** suggest that all of the galaxy mass,color and surrounding environment could play important roles in triggering radio lobes in late-type galaxies.

关键词： galaxies:active galaxies:jets galaxies:spiral radio continuum:galaxies

DeepsurNet-NsGA II: Deep surrogate Model-Assisted Multi-Objective Evolutionary Algorithm for Enhancing Leg Linkage in Walking Robots

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Computers, Materials and Continua 2024年第1期81卷 229-249页

作者： Ibrayev s. Omarov B. Ibrayeva A. Momynkulov z. Joldasbekov Institute of Mechanics and Engineering Almaty 050000 Kazakhstan Department of Mathematical and Computer Modeling International Information Technology University Almaty 050000 Kazakhstan Department of Information systems Al-Farabi Kazakh National University Almaty 050000 Kazakhstan

This research paper presents a comprehensive investigation into the effectiveness of the DeepsurNet-NsGA II (Deep surrogate Model-Assisted Non-dominated sorting Genetic Algorithm II) for solving complex multi-objective optimization problems, with a particular focus on robotic leg-linkage design. The study introduces an innovative approach that integrates deep learning-based surrogate models with the robust Non-dominated sorting Genetic Algorithm II, aiming to enhance the efficiency and precision of the optimization process. Through a series of empirical experiments and algorithmic analyses, the paper demonstrates a high degree of correlation between solutions generated by the DeepsurNet-NsGA II and those obtained from direct experimental methods, underscoring the algorithm’s capability to accurately approximate the Pareto-optimal frontier while significantly reducing computational demands. The methodology encompasses a detailed exploration of the algorithm’s configuration, the experimental setup, and the criteria for performance evaluation, ensuring the reproducibility of results and facilitating future advancements in the field. The findings of this study not only confirm the practical applicability and theoretical soundness of the DeepsurNet-NsGA II in navigating the intricacies of multi-objective optimization but also highlight its potential as a transformative tool in engineering and design optimization. By bridging the gap between complex optimization challenges and achievable solutions, this research contributes valuable insights into the optimization domain, offering a promising direction for future inquiries and technological innovations. © 2024 The Authors. Published by Tech science Press.

关键词： deep learning genetic algorithm Multi-objective optimization surrogate model walking robots

structural basis for polyuridine tract recognition by sARs-CoV-2 Nsp15

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Protein & Cell 2024年第7期15卷 547-552页

作者： Fumiaki Ito Hanjing Yang z.Hong zhou Xiaojiang s.Chen Molecular and Computational Biology Department of Biological SciencesUniversity of Southern CaliforniaLos AngelesCA 90089United States Department of Microbiology Immunology and Molecular GeneticsUniversity of CaliforniaLos AngelesCA 90095United States California Nanosystems Institute University of CaliforniaLos AngelesCA90095United States Genetic Molecular and Cellular Biology ProgramKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90089United States Norris Comprehensive Cancer Center University of Southern CaliforniaLos AngelesCA 90089United States Center of Excellence in NanoBiophysics University of Southern CaliforniaLos AngelesCA 90089United States

Dear Editor,Coronaviruses have evolved a wide array of tactics to evade host antiviral *** host cells detect invading foreign nucleic acids including viral genome and viral replication intermediates,they activate interferon(IFN)signaling via cytoplasmic pattern recognition receptors(Kang et al.,2002;Kato et al.,2006).Remarkable stealth activities exhibited by coronaviruses are facilitated by a series of non-structural proteins(Nsps),such as Nsp15(Deng and Baker,2018;Deng et al.,2019;Hackbart et al.,2020),which is a uridine-specific endoribonuclease that mediates evasion of host detection of viral double-stranded RNA(dsRNA)(Bhardwaj et al.,2004;Deng et al.,2017;Frazier et al.,2021;Ivanov et al.,2004).Nsp15 targets a polyuridine[poly(U)]tract on the coronavirus negative strand RNA(Hackbart et al.,2020).Nsp15 limits the abundance and length of poly(U)within the negative strand RNA 5ʹ-extension by trimming down the initially synthes.z.d poly(U)lead sequence to the optimal length that can suppress dsRNA formation but still serves as a template for poly(A)tail of the positive strand genome of the coronaviruses(Hofmann and Brian,1991).

关键词： p15 interferon template