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Effect of an amalgamated antibiotic and its connection to cytogenotoxicity and histo-architectural malformations in stinging catfish

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Emerging Contaminants 2022年第1期8卷 381-390页

作者： Mostt Tajnova Islam golam mohammod mostakim Md golam Azom Umme Ohida Rahman Mst Mansura Khan Mohd golam Quader Khan M.Sadiqul Islam Department of Fisheries Biology&Genetics Bangladesh Agricultural UniversityMymensingh2202Bangladesh Graduate Training Institute(GTI) Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Marine Fisheries Science Bangladesh Agricultural UniversityMymensingh2202Bangladesh

Intensive fish farming has an excessive prevalence of infection and is typically controlled by the administration of *** amalgamated antibiotics are a relatively novel therapeutic idea and more effective than traditional antibiotic monotherapy,they can also have a toxic effect on the fish body when it is administered *** study investigated the cyto-genotoxic effects on erythrocytes and histo-architectural malformations in the liver and kidneys of stinging catfish(Heteropneustes fossilis)in relation to Enrocip plus use as an amalgamated antibiotic *** experimental fish with an initial average weight of 17.38±1.94 g were divided into four treatment groups with antibiotic doses:according to the recommendation of the manufacturer 0.167 mg/ml Enrocip plus was used as a standard dose(x)and it was treated as T3,while 0%of the standard dose(0×mg/ml),1/2×(0.083 mg/ml),and 2×(0.333 mg/ml)were treated as T1,T2 and T4,respectively for a period of 30 *** observed erythrocyte cellular deformities(ECD)were twin,tear-drop,serrated,tail budded and de-membranated cells,whereas the erythrocyte nuclear deformities(END)were a nuclear bridge,bi-nucleus,nuclear termination,karyopyknosis,and micronucleus at different concentrations of Enrocip *** ECD and END percentages experienced the interaction of antibiotic dose and exposure time,and were significantly different(P<0.01).Significant changes in hepatocytes,mild to severe necrosis,vacuole formation,and hepatopancreas damage were also observed in the liver of the treated fish whereas highly degraded renal tubules and hematopoietic tissue,glomerular occlusion,and vacuolation were evident in the *** current investigation fully emphasizes the adverse effects of amalgamated antibiotics on the cytogenotoxicity and the histomorphology of the kidneys and liver of ***,the use of an amalgamated antibiotic in aquaculture must be carefully evaluated.

关键词： Antibiotic Cytotoxicity Genotoxicity Histomorphological defects Stinging catfish

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Reduction of epinephrine in the lumbar spinal cord following repetitive blast-induced traumatic brain injury in rats

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Neural Regeneration Research 2024年第7期19卷 1548-1552页

作者： Shigeharu Tsuda Mustafa golam Jiamei Hou Kevin K.W.Wang Floyd J.Thompson Prodip Bose Brain Rehabilitation Research Center Malcom Randall VA Medical CenterNorth Florida/South Georgia Veterans Health SystemGainesvilleFLUSA Department of Anesthesiology College of MedicineUniversity of FloridaGainesvilleFLUSA Department of Emergency Medicine University of FloridaGainesvilleFLUSA Department of Neuroscience University of FloridaGainesvilleFLUSA Department of Neurology University of FloridaGainesvilleFLUSA

Traumatic brain inju ry-induced unfavorable outcomes in human patients have independently been associated with dysregulated levels of monoamines,especially epinephrine,although few preclinical studies have examined the epinephrine level in the central nervous system after traumatic brain *** has been shown to regulate the activities of spinal motoneurons as well as increase the heart rate,blood pressure,and blood flow to the hindlimb ***,the purpose of the present study was to determine the impact of repeated blast-induced traumatic brain injury on the epinephrine levels in seve ral function-s pecific central nervous system regions in *** three repeated blast injuries at 3-day intervals,the hippocampus,motor cortex,locus coeruleus,vestibular nuclei,and lumbar spinal cord were harvested at post-injury day eight and processed for epinephrine assays using a high-sensitive electrochemical detector cou pled with high-performance liquid *** results showed that the epinephrine levels were significantly decreased in the lumbar spinal cord tissues of blast-induced traumatic brain injury animals compared to the levels detected in age-and sex-matched sham *** other function-specific central nervous system regions,although the epinephrine levels were slightly altered following blast-induced tra u matic brain injury,they were not statistically *** results suggest that blast injury-induced significant downregulation of epinephrine in the lumbar spinal cord could negatively impact the motor and cardiovascular *** is the first repo rt to show altered epinephrine levels in the spinal cord following repetitive mild blast-induced traumatic brain injury.

关键词： balance blood flow cardiovascular system central nervous system epinephrine ischemic damage lumbar spinal cord muscle tone repeated blast spasticity traumatic brain injury

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Repercussion of salinity on hematological parameters and tissue morphology of gill and kidney at early life of tilapia

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Aquaculture and Fisheries 2024年第2期9卷 256-264页

作者： Azhar Ali Md golam Azom Bhakta Supratim Sarker Hasu Rani Md Samsul Alam m.sadiqul islam*department of fisheries biology and genetics bangladesh agricultural universitymymensingh2202bangladesh

This study was attempted to reveal the changes in three hematological parameters such as blood hemoglobin,number of white blood cells(WBCs)and number of red blood cells(RBCs)and one biochemical(e.g.,glucose)parameter along with the changes in histomorphological structures of gills and kidney of Nile tilapia fry reared in saline *** experimental set up were used for two different age groups-5 days-after-hatch(5DAH)and 15 days-after-hatch(15DAH)-to test a novel hypothesis:if a little difference in the age during the first exposure to saline water could produce any variation in the *** were placed into 6 plastic drums having six different salinity levels:0,5,10,15,20 and *** 60 days,at least 5 individuals were taken out from each drum to observe the above-hematological and histomorphological parameters.A two-way-ANOVA revealed that,except for hemoglobin,all the observed parameters have been affected the effect of age×salinity interaction(P<0.05).Between the two age groups,only the overall average glucose value and RBC count were significantly *** various salinity levels,only RBC and WBC counts differed ***,the mean glucose value,RBC counts and WBC count at different salinities differed significantly from the base mean value of each *** regard to the histomorphological structure of the gills and kidney,various malformations were *** hypertrophy,epithelial uplifting and epithelial necrosis were present as gill degenerations,hyperplasia was prevalent across almost all salinity *** the other hand,glomerular necrosis,pyknotic nucleus,hyaline droplets degeneration,shrinking of the glomeruli,*** observed in kidney *** assisting to understand the effects of salinity stress,all these data on tilapia fry will help to determine the prospects and scope of culturing the species in high-salinity water.

关键词： Nile tilapia Salinity Blood parameters Histomorphology Age groups

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Microplastic Impacts on Greenhouse Gases Emissions in Terrestrial Ecosystems

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Open Journal of Soil Science 2024年第1期14卷 64-80页

作者： Tazeen Fatima Khan M. M. golam Rabbani Department of Soil Water and Environment University of Dhaka Dhaka Bangladesh Lancaster Environment Centre University of Lancaster Lancaster UK

Microplastics can influence global climate change by regulating the emissions of greenhouse gases from different ecosystems. The effects of microplastics in terrestrial ecosystems are still not well studied particularly greenhouse gases emissions. Thus, we conducted a laboratory experiment over a period of 90 days with two types of microplastics (differing in their chemical structure), high density polyethylene (HDPE) and low density polyethylene (LDPE), which were applied to the soil at a rate of 0% to 0.1% (w/w). The overarching aim was to investigate the effects of microplastic type, microplastic concentration and days of exposure on greenhouse gases emissions. We also used original and artificially weathered microplastics (the same HDPE and LDPE) to make a comparison of greenhouse gases emissions between the original microplastics treated soils and the soils treated with weathered microplastics. Our findings showed that HDPE and LDPE microplastics significantly increased the emissions of greenhouse gases from the soil than that of the control soils. Emissions were increased with the increases in the level of microplastic in the soil. The weathered microplastic emitted greater quantity of greenhouse gases compared to that of the original microplastics. In contrast to a low initial emission quantity, the emissions were gradually increased at the termination of the experiment. Our experiment on the emissions of greenhouse gases from the soil vis-à-vis microplastic additions indicated that the microplastic increased the emissions of greenhouse gases in terrestrial ecosystems, and pervasive microplastic impacts may have consequences for the global climate change. Greenhouse gases emissions from the soil not only depend on the type and concentration of the microplastic, but also on the days of exposure to the microplastic.

关键词： Microplastic Climate Change Greenhouse Gas Type Concentration

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Contribution to the Full 3D Finite Element Modelling of a Hybrid Stepping Motor with and without Current in the Coils

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Journal of Electromagnetic Analysis and Applications 2024年第2期16卷 11-23页

作者： Belemdara Dingamadji Hilaire Mbaïnaïbeye Jérôme Guidkaya golam Department of Physics and Engineering Sciences University of N&#8217Djamena N&#8217Djamena Chad Department of Physics University of Moundou Moundou Chad Department of Physics University of Ngaoundere Ngaoundere Cameroon

The paper presents our contribution to the full 3D finite element modelling of a hybrid stepping motor using COMSOL Multiphysics software. This type of four-phase motor has a permanent magnet interposed between the two identical and coaxial half stators. The calculation of the field with or without current in the windings (respectively with or without permanent magnet) is done using a mixed formulation with strong coupling. In addition, the local high saturation of the ferromagnetic material and the radial and axial components of the magnetic flux are taken into account. The results obtained make it possible to clearly observe, as a function of the intensity of the bus current or the remanent induction, the saturation zones, the lines, the orientations and the magnetic flux densities. 3D finite element modelling provide more accurate numerical data on the magnetic field through multiphysics analysis. This analysis considers the actual operating conditions and leads to the design of an optimized machine structure, with or without current in the windings and/or permanent magnet.

关键词： Modelling 3D Finite Elements Magnetic Flux Hybrid Stepping Motor

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Quantifying River Bank Erosion and Accretion Patterns along the Gorai River in Kushtia, Bangladesh: A Geospatial Analysis Utilizing GIS and Remote Sensing Techniques

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Journal of Geographic Information System 2024年第1期16卷 70-88页

作者： Chisti Muzahid Samsunnahar Popy Rifat Islam Md. Shafiqul Ahsan Emon Md. Selim Reja Md. Mustafizur Rahman Jubayer Hoque Md. golam Rabbani Saim Raiyan Department of Environmental Science and Disaster Management Bangabandhu Sheikh Mujibur Rahman Science and Technology University Dhaka Bangladesh

River bank erosion is a natural process that occurs when the water flow of a river exceeds the bank’s ability to withstand it. It is a common phenomenon that causes extensive land damage, displacement of people, loss of crops, and infrastructure damage. The Gorai River, situated on the right bank of the Ganges, is a significant branch of the river that flows into the Bay of Bengal via the Mathumati and Baleswar rivers. The erosion of the banks of the Gorai River in Kushtia district is not a recent occurrence. Local residents have been dealing with this issue for the past hundred years, and according to the elderly members of the community, the erosion has become more severe activities. Therefore, the main objective of this research is to quantify river bank erosion and accretion and bankline shifting from 2003 to 2022 using multi-temporal Landsat images data with GIS and remote sensing technique. Bank-line migration occurs as a result of the interplay and interconnectedness of various factors such as the degree of river-related processes such as erosion, transportation, and deposition, the amount of water in the river during the high season, the geological and soil makeup, and human intervention in the river. The results show that the highest eroded area was 4.6 square kilometers during the period of 2016 to 2019, while the highest accreted area was 7.12 square kilometers during the period of 2013 to 2016. However, the erosion and accretion values fluctuated from year to year.

关键词： Erosion and Accretion Geographic Information System (GIS) Remote Sensing Satellite Image Bankline Shifting

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Rural Resilience: A Comprehensive Study on Water Supply, Sanitation, Disease Patterns, and Hygiene Practices in Munshiganj, Bangladesh

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Journal of Environmental Protection 2024年第1期15卷 63-75页

作者： Jubayer Hoque Rifat Islam Md. Mustafizur Rahman Md. golam Rabbani Md. Selim Reja Saifur Rahman Soykat Saim Raiyan Md. Shafiqul Ahsan Emon Sakil Khan Department of Environmental Science and Disaster Management Bangabandhu Sheikh Mujibur Rahman Science and Technology University Gopalgnj Bangladesh Department of Political Science Bangabandhu Sheikh Mujibur Rahman Science and Technology University GopalgnjBangladesh Department of Statistics Bangabandhu Sheikh Mujibur Rahman Science and Technology University Gopalgnj Bangladesh

This research project investigates the current status of water supply, sanitation, and hygiene practices in Munshiganj District, Bangladesh. Data collection involved a structured questionnaire and a reconnaissance survey. Findings reveal that 30% of individuals rely on surface water (hand-tube wells, rivers, and ponds), prioritized as canal > river > pond, while 70% depend on groundwater (subterranean electric motor, deep tube-well). Drinking water is generally sufficient, with 95% reporting adequacy throughout the year. About 45% use hand tube-well water, 28% use deep tube-well water, and 11% use supply tap water for various purposes. Bathing trends include underground water through electric motor > pond > hand tube-well water > river, while for cooking, the order is underground water through electric motor > pond > hand tube-well water > river. Toilet water supply ranks as supply tap water > hand tube-well water > deep tube-well water. Although sanitation awareness is high, some lack knowledge of good hygiene practices. After defecating, handwashing methods include soap, ash, soil, or water. Children’s waste disposal varies, with some discarding it in open areas. Approximately 40% suffer from diseases like Diarrhoea due to unsafe water, primarily affecting children and elders. Training exists, but a significant portion lacks sanitation education. Dry skin or exposure to cold water may cause temporary irritation. Local government involvement in sanitation efforts is less active compared to non-governmental organizations. Results emphasize the need to enhance community awareness of safe water supplies and sanitation practices. .

关键词： Water Supply Sanitation Practices Hygiene Awareness Groundwater Dependency Community Health Intervention

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Effect of Trimetazidine on Functional Capacity in Patient with Ischaemic Cardiomyopathy (TOFCAPI)

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International Journal of Clinical Medicine 2024年第2期15卷 55-67页

作者： Mohsin Ahmed golam Morshed Mahmood Hasan Khan Md. Arifur Rahman Muhammed Aminur Razzaque Shariful Islam Sayeedur Rahman Khan Chowdhury Md. Kudrat-E-Khuda Salahuddin Anis Shiblee Md. Habibur Rahman Department of Cardiology National Institute of Cardiovascular Diseases Dhaka Bangladesh Department of Cardiology Government Employee’s Hospital Dhaka Bangladesh Department of Cardiology Delta Hospital Ltd. Dhaka Bangladesh IPDI Foundation Dhaka Bangladesh

Objective: This study aimed to evaluate the efficacy of trimetazidine on exercise capacity via a six-minute walk test in patients with ischaemic cardiomyopathy and also evaluate the effect of trimetazidine on left ventricular function via echocardiography in the same population. Methods: This prospective observational study, conducted at the National Institute of Cardiovascular Diseases in Dhaka, Bangladesh, enrolled 200 patients with ischaemic cardiomyopathy and a depressed left ventricular ejection fraction (LVEF Results: In this study (n = 200) of ischaemic cardiomyopathy patients, the mean age was 58 years, with 76% of the patients being male. All study subjects received GDMT (Guideline-Directed Medical Therapy) for angina and heart failure. Those who received the modified released form of trimetazidine developed lesions during the 1st and 2nd follow-ups, during which the LVEF, LVIDd, and six-minute walk distance significantly improved (p Conclusion: The findings of the present study demonstrated that the addition of modified-release trimetazidine to GDMT can improve exercise capacity and left ventricular function in patients with ischaemic cardiomyopathy.

关键词： Bangladesh Heart Failure Exercise Capacity Trimetazidine Ischaemic Cardiomyopathy

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A New Handover Management Model for Two-Tier 5G Mobile Networks

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Computers, Materials & Continua 2022年第6期71卷 5491-5509页

作者： Mohammad Arifin Rahman Khan Mohammed golam Kaosar Mohammad Shorfuzzaman Kire Jakimoski Department of Computer Science and Engineering Bangladesh UniversityDhaka1207Bangladesh Discipline of IT Media and CommunicationsMurdoch UniversityPerthWA6150Australia Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Faculty of Informatics AUE-FON UniversitySkopjeRepublic of North Macedonia

There has been an exponential rise in mobile data traffic in recent times due to the increasing popularity of portable devices like tablets,smartphones,and *** rapid rise in the use of these portable devices has put extreme stress on the network service providers while forcing telecommunication engineers to look for innovative solutions to meet the increased *** solution to the problem is the emergence of fifth-generation(5G)wireless communication,which can address the challenges by offering very broad wireless area capacity and potential cut-power *** application of small cells is the fundamental mechanism for the *** use of small cells can enhance the facility for higher capacity and ***,it must be noted that small cells deployment will lead to frequent handovers of mobile *** the importance of small cells in 5G,this paper aims to examine a new resource management scheme that can work to minimize the rate of handovers formobile phones through careful resources allocation in a two-tier ***,the resource management problem has been formulated as an optimization issue thatwe aim to overcome through an optimal *** find a solution to the existing problem of frequent handovers,a heuristic approach has been *** solution is then evaluated and validated through simulation and testing,during which the performance was noted to improve by 12%in the context of handover ***,this model has been observed to be more efficient as compared to the existing model.

关键词： Two-tier mobile networks small cell densification management of mobility handover cost average throughput power consumption

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Selective superoxide radical generation for glucose photoreforming into arabinose

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Journal of Energy Chemistry 2022年第11期31卷 324-331,I0009页

作者： Jiu Wang Heng Zhao Peng Liu Nael Yasri Na Zhong Md golam Kibria Jinguang Hu Department of Chemical and Petroleum Engineering University of CalgaryCalgaryAlberta T2N 1N4Canada School of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093YunnanChina

Biomass photorefinery to produce fuels and valuable chemicals is a promising approach to alleviating the energy crisis and achieving carbon ***,precisely modulating the photocatalytic conversion of biomass into value-added chemicals is still *** we demonstrate a feasible strategy to selectively produce arabinose via oriented glucose oxidation to gluconic acid,followed by the decarboxylation process for C1-C2 bond *** realize this process,gold nanoparticles(Au NPs)modified carbon nitride(AuCN)is rationally designed to regulate the electron transfer behavior of pristine carbon nitride from a two-electron pathway to a single-electron *** allows selective production of superoxide(·O_(2)^(-))from oxygen reduction reaction which triggers glucose oxidation into gluconic *** addition,the arabinose production is synergistically promoted by the improved charge separation efficiency and extended visible-light absorption via localized surface plasmon resonance(LSPR)of Au *** work demonstrates an example of a mechanism-guided catalyst design to improve biofuels/chemicals production from biomass photorefinery.

关键词： Biomass photorefinery Selective glucose photoreforming Carbon nitride LSPR Oxygen reduction reaction(ORR)

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