检索结果-南通市图书馆

Ecology,growth and management of black locust(Robinia pseudoacacia L.),a non-native species integrated into European forests

引用

journal of Forestry Research 2020年第4期31卷 1081-1101页

作者： Valeriu-Norocel Nicolescu Károly Rédei William L.mason Torsten Vor Elisabeth Poetzelsberger jean-Charles Bastien Robert Brus Tibor Bencat martinaDodan Branislav Cvjetkovic Sinisa Andrasev Nicola La Porta Vasyl Lavnyy Dejan mandzukovski Krasimira Petkova Dusan Rozenbergar Radoslaw Wasik godefridus m.j.mohren maria Cristina monteverdi Brigitte musch marcin Klisz Sanja Peric Ljiljana Keca Debbie Bartlett Cornelia Hernea michal Pástor Faculty of Silviculture and Forest Engineering Transylvania University of Brasov500123 BrasovRomania Forest Research Institute Budapest 9600Hungary Forest Research Northern Research StationRoslinMidlothian EH259SYUK Faculty of Forest Sciences and Forest Ecology University Georg-August37077 GöttingenGermany University of Natural Resources and Life Sciences Peter Jordan Str.821190 ViennaAustria INRA Centre Val de Loire 45075 ArdonOrléansFrance Biotechnical Faculty University of Ljubljana1000 LjubljanaSlovenia Technical University Ul.T.G.Masaryka 2496053 ZvolenSlovakia Croatian Forest Research Institute 10450 JastrebarskoCroatia Faculty of Forestry University of Banja LukaStepe Stepanovica 75a78000 Banja LukaBosnia and Herzegovina Institute of Lowland Forestry and Environment AntonaČehova 13dNovi Sad 21000Serbia Fondazione Edmund mach Via E.Mach 138010 S.Michele a/AdigeItaly Department of Silviculture Ukrainian National Forestry UniversityL’viv 79057Ukraine Public enterprise makedonski sumi Pero Nakov bbKosta Novakovic 12Skopje 1000Republic of North Macedonia University of Forestry 1797 Sofi aBulgaria Faculty of Forestry University of Agriculture31-425 KrakówPoland Department of Forest Ecology and Forest management Group University of Wageningen6700 WageningenThe Netherlands Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria Viale Santa Margherita8052100 ArezzoItaly UmR 0588 INRA ONF BioForA2163 Avenue de la Pomme de PinCS 4000145075 ArdonOrléans CedexFrance Forest Research Institute Braci Lesnej Streetno.305-090 Sekocin StaryRaszynPoland Faculty of Forestry University of Belgrade1Kneza Viseslava StreetBelgrade 11030Serbia Faculty of Engineering and Science University of GreenwichCentral AvenueChatham MaritimeLondon ME44TBUK Faculty of Horticulture and Forestry Banat’s University of Agricultural Sciences and Veterinary Medicine300645 TimisoaraRomania National Forest Centre Forest Research InstituteT.G.Masaryka 2296092 ZvolenSlovakia

Black locust(Robinia pseudoacacia L.),a species native to the eastern North America,was introduced to Europe probably in 1601 and currently extends over2.3×10~6 *** has become naturalized in all sub-mediterranean and temperate regions rivaling Populus *** the second most planted broadleaved tree species worldwide after Eucalyptus *** wide-spreading planting is because black locust is an important multipurpose species,producing wood,fodder,and a source of honey as well as bio-oil and *** is also important for carbon sequestration,soil stabilization and re-vegetation of landfills,mining areas and wastelands,in biotherapy and *** Europe,black locust is drought tolerant so grows in areas with annual precipitation as low as 500-550 *** tolerates dry,nutrient poor soils but grows best on deep,nutrient-rich,well-drained *** is a fast-growing tree and the height,diameter and volume growth peak before the age of *** mostly regenerates vegetatively by root suckers under a simple coppice system,which is considered the most cost-effective management *** also regenerates,but less frequently,by stool *** early silviculture in production forests includes release cutting to promote root suckers rather than stool shoots,and cleaning-respacing to remove low-quality stems,reduce the number of shoots per stool,and adjust spacing between root *** addition,early,moderate and frequent thinning as well as limited pruning are carried out focusing on crop *** species is regarded as invasive in several European countries and its range here is expected to expand under predicted climate changes.

关键词： Black locust Ecology Invasiveness Climate change management

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance

引用

Cancer Drug Resistance 2021年第4期4卷 904-922页

作者： Ornella Randazzo Stella m.Cascioferro Camilla Pecoraro Widad Ait Iddouch Amir Avan Barbara Parrino Daniela Carbone Ugo Perricone godefridus j.Peters Patrizia Diana Elisa Giovannetti Department of medical Oncology Cancer Center AmsterdamAmsterdam UMCVU University Medical CenterAmsterdam 1081 HVThe Netherlands Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche(STEBICEF) Universitàdegli Studi di PalermoPalermo 90133Italy metabolic Syndrome Research Center Mashhad University of Medical SciencesMashhad 91886-17871Iran Cancer Research Center Mashhad University of Medical SciencesMashhad 91886-17871Iran Student Research Committee School of MedicineMashhad University of Medical SciencesMashhad 91886-17871Iran Drug Discovery Unit Fondazione Ri.MEDPalermo 90128Italy Department of Biochemistry Medical University of GdanskGdansk 80-210Poland Cancer Pharmacology Lab AIRC Start Up UnitFondazione Pisana per la ScienzaPisa 56124Italy.

Aim:Because mutations of splicing factor 3B subunit-1(SF3B1)have been identified in 4%of pancreatic ductal adenocarcinoma(PDAC)patients,we investigated the activity of new potential inhibitors of SF3B1 in combination with gemcitabine,one of the standard drugs,in PDAC cell ***:One imidazo[2,1-b][1,3,4]thiadiazole derivative(IS1)and three indole derivatives(IS2,IS3 and IS4),selected by virtual screening from an in-house library,were evaluated by the sulforhodamine-B and wound healing assay for their cytotoxic and antimigratory activity in the PDAC cells SUIT-2,Hs766t and Panc05.04,the latter harbouring the SF3B1 *** effects on the splicing pattern of proto-oncogene recepteur d’origine nantais(RON)and the gemcitabine transporter human equilibrative nucleoside transporter-1(hENT1)were assessed by PCR,while the ability to reduce tumour volume was tested in spheroids of primary PDAC ***:The potential SF3B1 modulators inhibited PDAC cell proliferation and prompted induction of cell *** compounds showed an interesting anti-migratory ability,associated with splicing RON/ΔRON shift in SUIT-2 cells after 24 h ***,IS1 and IS4 potentiated the sensitivity to gemcitabine in both conventional 2D monolayer and 3D spheroid cultures,and these results might be explained by the statistically significant increase in hENT1 expression(Pmodulation to develop effective drug combinations against PDAC.

关键词： Pancreatic ductal adenocarcinoma gemcitabine indole derivatives anti-proliferative activity anti-migratory activity SF3B1 RON hENT1

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gemcitabine followed by radiotherapy in treatment of newly diagnosed high-grade gliomas

引用

journal of Cancer metastasis and Treatment 2016年第1期2卷 188-194页

作者： maha El-Naggar mervat Omar Ahmed Elgeriany godefridus j.Peters Amina mostafa Samir Shehata Department of medical oncology Assiut University HospitalAssiut 71515Egypt Department of Neurosurgery Assiut University HospitalAssiut 71515Egypt Department of medical Oncology VU University Medical Center1081 HV Amsterdamthe Netherlands

Aim:High-grade glioblastoma multiforme(GBm)has a poor median overall survival(OS).The standard treatment after surgery is temozolomide and radiotherapy(RTH).Patients with unmethylated methylguanine-methyltransferase promoter(mGmT)have no or little benefit from temozolomide and are eligible for alternative *** is a good *** aimed to evaluate the combination of gemcitabine with RTH in newly diagnosed ***:The study was a prospective phase II *** patients were required to have histologically proven anaplastic astrocytoma or *** underwent biopsies or subtotal *** treatment consisted of fixed-dose rate gemcitabine 175 mg/m^(2) weekly followed after 24 h by standard cranial RTH for 6 *** response was evaluated by macdonald *** case of progression,patients received temozolomide(200 mg/m^(2)/5 days every 28 days).Results:T hirty patients w ith a median age of 52 years(30-69),73%/27%m ale/female,t he Eastern Cooperative Oncology Group performance status 1(range 0-2)were *** patients had a partial-response(17%)and 13 stable-disease(43%).median time to progression was 7.88 months(95%CI 6.1-9.69)and OS was 11.77 months(95%CI 9.97-13.56).The treatment was well tolerated with grade-3 neutropenia in 3,grade-3 anemia in 2 and impaired liver enzymes in 1 ***:Gemcitabine followed by radiotherapy is active and promising regimen in newly diagnosed *** uptake is easy,with a long local retention of active metabolites,precluding systemic side effects of *** a phase III study this treatment should be evaluated in patients with unmethylated mGmT promoter who will not benefit from temozolomide.

关键词： Gemcitabine radiation glioblastoma multiforma temozolomide

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：