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世界核心医学期刊文摘（神经病学分册） 2005年第7期1卷 27-28页

作者： gnanalingham k.k. Bhattacharjee S. Pennington R. 陈云春 Bri ndhoven Queens Drive LondonW3 0HR United Kingdom

Objective: To report the quantitative assessment of visual fields(VF) in patie nts with pituitary macroadenomas, and the time course and predictive factors for recovery of vision. Methods:Retrospective study of 41 patients with pituitary a denomas and visual disturbance. Patients underwent pre-and postoperative VF ass essment at one week, three to six months, one year, two years, and five years us ing the Humphrey field analyser, which gives a quantitative measure of VF in eac h quadrant. Results:36/41 patients (88%) presented with a visual disturbance. M ean(SEM) duration of symptoms was 94 (50) weeks (range 0.5 to 1500); 12 (29%) h ad optic atrophy at presentation. Impairment of VF was greatest in the upper tem poral quadrant, followed by the lower temporal. VF recovery was progressive and apparent even at the five year follow up (p ks; p < 0. 05), better preoperative visual acuity (p < 0.05), and a smaller degree of impai rment in preoperative lateral quadrant VF (p < 0.01) than those whose VF only im proved. On multivariate analysis, the only predictive factor for VF recovery was the degree of impairment in VF preoperatively. Conclusions:Transphenoidal surge ry for pituitary macroadenoma results in a progressive recovery of VF in 95%of patients. The extent of the VF recovery is mainly dependent on the preoperative VF deficit, which emphasises the need for early intervention in these patients.

关键词：垂体腺瘤视野分析仪症状持续时间 Humphrey progressive presentation pituitary 视觉障碍 preoperative shorter

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经蝶骨垂体腺瘤摘除术后视野的恢复时程:一项预测预后的良好指标

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世界核心医学期刊文摘(眼科学分册) 2005年第7期 1-1页

作者： gnanalingham k.k.Bhattacharjee S. Pennington R. 陈立军 Brindhoven Queens DriveLondon W30HR United Kingdom

Objective: To report the quantitative assessment of visual fields (VF) in patients with pituitary macroadenomas, and the time course and predictive factors for recovery of vision. Methods: Retrospective study of 41 patients with pituitary adenomas and visual disturbance. Patients underwent pre and postoperative VF assessment at one week, three to six months, one year, two years, and five years using the Humphrey field analyser, which gives a quantitative measure of VF in each quadrant. Results: 36/41 patients (88% ) presented with a visual disturbance. Mean (SEM) duration of symptoms was 94 (50) weeks (range 0.5 to 1500); 12 (29% ) had optic atrophy at presentation. Impairment of VF was greatest in the upper temporal quadrant, followed by the lower temporal. VF recovery was progressive and apparent even at the five year follow up (pks; P< 0.05), better preoperative visual acuity (p< 0.05), and a smaller degree of impairment in preoperative lateral quadrant VF (p< 0.01) than those whose VF only improved. On multivariate analysis, the only predictive factor for VF recovery was the degree of impairment in VF preoperatively. Conclusions: Transphenoidal surgery for pituitary macroadenoma results in a progressive recovery of VF in 95% of patients. The extent of the VF recovery is mainly dependent on the preoperative VF deficit, which emphasises the need for early intervention in these patients.

关键词：垂体腺瘤蝶骨颅骨损害程度时程视野

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对儿科核查工作情况的审核

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世界核心医学期刊文摘（儿科学分册） 2005年第7期1卷 4-4页

作者： John C.M. Mathew D.E. gnanalingham M.G. 李开 Academic Division of Child Health School of Human Development University Hospital Nottingham NG7 2UH United Kingdom Dr.

An audit of audits at a children’s hospital over a six year period showed that 27.8%fulfilled the criteria for a full audit and 22.2%were *** is recommended that newcomers to audit are given training on audit methodo... 详细信息

关键词：核查工作核查标准儿童医院

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