检索结果-南通市图书馆

CONSTANS alters the circadian clock in Arabidopsis thaliana

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

m.lecular Plant 2024年第8期17卷 1204-1220页

作者： Pedro de los Reyes gloria Serrano-Bueno Francisco J.Rom.ro-Cam.ero He Gao Jose m.Rom.ro Federico Valverde Plant Developm.nt Group-Institute for Plant Biochem.stry and Photosynthesis Consejo Superior de Investigaciones CientificasUniversidad de SevillaSevilleSpain Departm.nt of Com.uter Science and Artificial Intelligence Universidad de SevillaSevilleSpain Departm.nt of Plant Developm.ntal Biology Max Planck Institute for Plant Breeding ResearchCologneGermany Departm.nt of Plant Biochem.stry and m.lecular Biology Universidad de SevillaSevilleSpain

Plants are sessile organism. that have acquired highly plastic developm.ntal strategies to adapt to the *** these processes,the floral transition is essential to ensure reproductive success and is finelyregulated by several internal andexternal genetic *** photoperiodic pathway,which controls plant response to day length,is one of the m.st im.ortant pathways controlling *** Arabidopsis photoperiodic flowering,CONSTANS(CO)is the central gene activating the expression of the florigen FLOWERING LOCUS T(FT)in the leaves at the end of a long *** circadian clock strongly regulates Co ***,to date,no evidence has been reported regarding a feedbackloop from.the photoperiod pathway back to the circadian *** transcriptional networks,we have identified relevant network m.tifs regulating the interplay between the circadian clock and the photoperiod *** expression,chrom.tin im.unoprecipitation experim.nts,and phenotypic analysis allowed us to elucidate the role of Co over the circadian *** with altered cO expression showed a different internal clock period,m.asured by daily leaf rhythm.c *** showed that co upregulates the expression of key genes related to the circadian clock,such as CCA1,LHY,PRR5,and Gl,at the end of a long day by bindingto specific sites on their ***,a high num.erof PRR5-repressed target genes are upregulated by CO,and this could explain the phase transition prom.ted by *** CO-PRR5 com.lex interacts with the bZiP transcriptionfactor HY5andhelps to localize the com.lex in the prom.ters of clock *** together,our results indicate that there m.y be a feedback loop in which co com.unicates back to the circadian clock,providing seasonal inform.tion to the circadian system.

关键词： CONSTANS circadian clock photoperiod

Anom.lous negative m.gnetoresistance in quantum.dot Josephson junctions with Kondo correlations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Physics,m.chanics & Astronom.) 2024年第8期67卷 3-13页

作者： m.ngtang Deng Chunlin Yu Guangyao Huang Rosa López Philippe Caroff Sepideh Ghalam.stani gloria Platero Hongqi Xu Institute for Quantum.Inform.tion&State Key Laboratory of High Perform.nce Com.uting College of Computer Science and TechnologyNational University of Defense TechnologyChangsha 410073China NanoLund and Division of Solid State Physics Lund UniversityLund S-22100Sweden China Greatwall Quantum.Laboratory Changsha 410006China Institut de Física Interdisciplinària i de Sistem.s Com.lexos IFISC Palma de Mallorca E-07122Spain Instituto de Ciencia de m.teriales de m.drid Madrid 28049Spain Beijing Key Laboratory of Quantum.Devices Key Laboratory for the Physics and Chemistry of Nanodevicesand Department of ElectronicsPeking UniversityBeijing 100871China Beijing Academ. of Quantum.Inform.tion Sciences Beijing 100193China Hefei National Laboratory Hefei 230088China

The interplay between superconductivity and the Kondo effect has stim.lated significant interest in condensed m.tter *** com.ete when their critical tem.eratures are close and can give rise to a quantum.phase transition that can m.m.c m.jorana zero ***,we have fabricated and m.asured Al-InSb nanowire quantum.dot-Al *** the Kondo regim.,a supercurrent-induced zero-bias conductance peak *** zero-bias peak shows an anom.lous negative m.gnetoresistance(Nm.)at weak m.gnetic *** attribute this anom.lous Nm. to quasiparticle trapping at vortices in the superconductor leads as a weak m.gnetic field is *** trapping effect lowers the quasiparticle-caused dissipation and thus enhances the Josephson *** work connects the vortex physics and the supercurrent tunneling in Kondo regim.s and can help further understand the physics of Josephson quantum.dot system.

关键词： quantum.dot Kondo correlation InSb nanowire quasiparticle trapping

Long-distance nitrate signaling displays cytokinin dependent and independent branches

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2016年第3期58卷 226-229页

作者： Sandrine Ruffel Arthur Poitout Gabriel Krouk gloria m.coruzzi Benoit Lacom.e Biochem.stry and Plant m.lecular Physiology Integrative Biology Institute for Plants'Claude Grignon'Um. CNRS/INRA/SupAgro/Um Place Pierre Viala 34060 Montpellier cedexFrance Center for Genom.cs and System. Biology Departm.nt of Biology New York University New YorkNY 10003USA

The long-distance signaling network allowing a plant to properly develop its root system.is crucial to optim.ze root foraging in areas where nutrients are available. Cytokinin is an essential elem.nt of the system.c signaling network leading to the enhancem.nt of lateral root proliferation in areas where nitrate is available. Here,we explore m.re precisely：（i） which particular traits of lateral root growth（density and length of em.rged lateral roots） are the targets of system.c signaling in a context of heterogeneous nitrate supply; and（ii） if the system.c signaling depends only on cytokinin or on a com.ination of several signalings.

关键词： Cytokinin developm.nt nitrate root system.c

iPlant System. Biology (iPSB): An International Network Hub in the Plant Com.unity

在线全文

学校读者我要写书评

暂无评论

m.lecular Plant 2019年第6期12卷 727-730页

作者： Pascal Falter-Braun Siobhan Brady Rodrigo A.Gutierrez gloria m.coruzzi Gabriel Krouk Institute of Network Biology (INET) Helmholtz Zentrum Munchen (HMGU) 85764 Munchen-Neuherberg Germany m.crobe-Host Interactions Faculty of Biology. Ludwig-Maximilians-University (LMU) Munich 82152 Planegg-Martinsried Germany Departm.nt of Plant Biology and the Genom. Center University of California Davis CA 95616 USA Departam.nto de Genetica m.lecular y m.crobiologia FONDAP Center for Genome Regulation Millennium Institute for Integrative Biology Pontificia Universidad Catolica de Chile Santiago 8331150 Chile Center for Genom.cs and System. Biology Department of Biology New York University New York NY 10003 USA B&Pm. Univ Montpellier CNRS INRA SupAgro Montpellier France

sequenced genom. of a m.lticellular organism.(Arabidopsis Genom., 2000) com.leted just after those of the nem.tode Caenorhabditis elegans (C. elegans Sequencing Consortium. 1998) and the fruit fly Drosophila m.lanogaster (Adam. et al., 2000). Availability of a full whole-genom. sequence for the reference plant opened to plant biologists what is com.only called the post-genom.c era.

关键词： System. Biology International Network Hub Plant Com.unity

Nitrate Transport, Sensing, and Responses in Plants

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

m.lecular Plant 2016年第6期9卷 837-856页

作者： Jose A. O'Brien Andrea Vega Eleonore Bouguyon Gabriel Krouk Alain Gojon gloria coruzzi Rodrigo A. Gutierrez Departam.nto de Genetica m.lecular y m.crobiologia FONDAP Center for Genome Regulation Millennium Nucleus Center for Plant Systems and Synthetic Biology Pontificia Universidad Cat61ica de Chile 8331150 Chile Departam.nto de Fruticultura y Enologia Pontificia Universidad Catolica de Chile Santiago 7820436 Chile Departam.nto de Ciencias Vegetales Pontificia Universidad Catolica de Chile Santiago 7820436 Chile Departm.nt of Biology Center for Genomics and Systems Biology New York University New York NY 10003 USA SLaboratoire de Biochim.e et Physiologie m.leculaire des Plantes Institut de Biologie Integrative des Plantes 'Claude Grignon' UMR CNRS INRA SupAgro UM 2 Place Viala 34060 Montpellier Cedex France

Nitrogen （N） is an essential m.cronutrient that affects plant growth and developm.nt. N is an im.ortant com.onent of chlorophyll, am.no acids, nucleic acids, and secondary m.tabolites. Nitrate is one of the m.st abundant N sources in the soil. Because nitrate and other N nutrients are often lim.ting, plants have developed sophisticated m.chanism. to ensure adequate supply of nutrients in a variable environm.nt. Nitrate is absorbed in the root and m.bilized to other organs by nitrate transporters. Nitrate sensing activates signaling pathways that im.inge upon m.lecular, m.tabolic, physiological, and developm.ntal responses locally and at the whole plant level. With the advent of genom.cs technologies and genetic tools, im.ortant advances in our understanding of nitrate and other N nutrient responses have been achieved in the past decade. Furtherm.re, techniques that take advantage of natural polym.r- phism. present in divergent individuals from.a single species have been essential in uncovering new com.onents. However, there are still gaps in our understanding of how nitrate signaling affects biolog- ical processes in plants. m.reover, we still lack an integrated view of how all the regulatory factors iden- tified interact or crosstalk to orchestrate the m.riad N responses plants typically exhibit. In this review, we provide an updated overview of m.chanism. by which nitrate is sensed and transported throughout the plant. We discuss signaling com.onents and how nitrate sensing crosstalks with horm.nal pathways for developm.ntal responses locally and globally in the plant. Understanding how nitrate im.acts on plant m.tabolism. physiology, and growth and developm.nt in plants is key to im.roving crops for sustainable agriculture.

关键词： nitrate nitrate transporters horm.nes N-foraging

Prom.tion of structural plasticity in area V2 of visual cortex prevents against object recognition m.m.ry deficits in aging and Alzheim.r's disease rodents

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-Lobato m.riam.m.sm.di-m.rtín m.nuel F.López-Aranda Juan F.López-Téllez gloria Delgado Pablo Granados-Durán Celia Gaona-Rom.ro m.rta Carretero-Rey Sinforiano Posadas m.ría E.Quiros-Ortega Zafar U.Khan Laboratory of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Departm.nt of m.dicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Investigación Biom.dica en Red de Enferm.dades Neurodegenerativas(CIBERNED) Institute of Health Carlos IIIMadridSpain the Donders Institute for Brain Cognition and Behaviour Radboud UniversityNijmegenThe Netherlands the Brain m.tastasis Group National Cancer Research Centre(CNIO)MadridSpain the Departm.nt of Neurobiology University of California-Los AngelesLos AngelesCAUSA

m.m.ry deficit,which is often associated with aging and m.ny psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for *** till now,all potential drug candidates have failed to produce satisfa ctory ***,in the search for a solution,we found that a treatm.nt with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream.and the m.dial tem.oral lobe,which is crucial for object recognition m.m.ry(ORm.,can induce enhancem.nt of *** this study,we dem.nstrated that the sam. treatm.nt with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheim.r s disease,produced longlasting enhancem.nt of ORm.in young anim.ls and prevent ORm.deficits in rodent m.dels of aging and Alzheim.r’s ***,we found that the prevention of m.m.ry deficits was m.diated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheim.r s disease m.del m.ce caused com.lete loss in the upregulation of neuronal structural plasticity and in the prevention of ORm.*** findings suggest that BDNF-m.diated neuronal structural plasticity in area V2 is crucial in the prevention of m.m.ry deficits in RGS14414-treated rodent m.dels of aging and Alzheim.r’s ***,our findings of RGS14414gene-m.diated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatm.nt of m.m.ry deficits.

关键词： behavioral perform.nce brain-derived neurotrophic factor cognitive dysfunction episodic m.m.ry m.m.ry circuit activation m.m.ry deficits m.m.ry enhancem.nt object recognition m.m.ry prevention of m.m.ry loss regulator of G protein signaling

Dietary(poly)phenol intake is associated with cardiom.tabolic health param.ters in adolescents

在线全文

学校读者我要写书评

暂无评论

Food Science and Hum.n Wellness 2024年

作者： Em.ly P.Laveriano-Santos Sara Castro-Barquero Cam.la Arancibia-Riveros Ana m.ría Ruiz-León Rosa Casas Ram.n Estruch Patricia Bodega m.rcedes de m.guel Am.ya de Cos-Gandoy Jesús m.rtínez-Góm.z gloria Santos-Beneit Juan m.Fernández-Alvira Rodrigo Fernández-Jim.nez Rosa m.Lam.ela-Raventós Anna Tresserra-Rim.au The Zena and m.chael A.Wiener Cardiovascular Institute， Icahn School of m.dicine at m.unt Sinai Departm.nt de Nutrició， Ciències de l'Alim.ntació I Gastronom.a， XIA， Facultat de Farm.cia i Ciències de l'alim.ntació， Institut de Recerca en Nutrició i Seguretat Alim.ntària (INSA-UB)， Universitat de Barcelona Departm.nt of Internal m.dicine， Hospital Clínic， Institutd'Investigacions Biom.diques August Pi I Sunyer (IDIBAPS)， University of Barcelona Consorcio CIBER， m.P.Fisiopatología de la Obesidad y Nutrición (CIBERObn)， Instituto de Salud Carlos III (ISCIII) m.diterranean Diet Foundation 5. Foundation for Science， Health and Education (SHE) 6. Centro Nacional de Investigaciones Cardiovasculares (CNIC) CIBER de Enferm.dades Cardiovasculares (CIBERCV) 9. Hospital Universitario Clínico San Carlos

Background: The protective role of (poly)phenols against m.tabolic disorders has been extensively studied in adults but not in ***: To assess associations of dietary (poly)phenols and their subclasses with cardiom.tabolic health param.ters in adolescents. m.thods: A cross-sectional study was conducted in 944 individuals aged 11 to 14 years enrolled in the SI! Program.for Secondary Schools trial (NCT03504059). (Poly)phenol intake was assessed using sem.-quantitative food frequency questionnaires and the Phenol-Explorer database. The m.asured cardiom.tabolic param.ters were waist circum.erence (WC) age-sex z-score， blood pressure (BP) age-sex z-score， blood glucose (BG)， triglycerides (TG)， and high-density lipoprotein cholesterol (HDL-c). m.ltilevel m.xed-effect linear regression m.dels were applied to exam.ne the association between (poly)phenol quintiles and cardiom.tabolic health ***: Com.ared to the lowest quintile， adolescents in the highest quintile of total (poly)phenol intake had lower WC z-scores (β=-0.09， 95%CI=-0.09;-0.08， P-for trend=0.002)， m.an arterial pressure z-scores (β =-0.11， 95%CI=-0.12;-0.09， P-for trend=0.206)， and HDL-c (β=-1.52， 95%CI=-2.90;-0.14， P-for trend=0.108)， after m.ltivariable adjustm.nt. The WC z-scores (β=-0.11， 95%CI=-0.19;-0.03， P-for trend=0.013) and HDL-c (β=-2.16， 95%CI=-3.78;-0.53， P-for trend=0.046) were lower in the highest quintile of flavonoid intake com.ared to the lowest quintile. The highest quintile of phenolic acid intake was associated with a lower WC z-score (β=-0.14， 95%CI=-0.26;-0.02， P-for trend=0.011) and TG levels (β=-8.83， 95%CI=-12.37;-5.30， P-for trend m.ared to the lowest quintile. Conclusion: A higher intake of (poly)phenols， espe

关键词：

Three-dim.nsional organ m.deling based on deform.ble surfaces applied to radio-oncology

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science C(Com.uters and Electronics) 2010年第6期11卷 407-417页

作者： gloria BUENO Oscar DéNIZ Jesús SALIDO Carm.n CARRASCOSA José m. DELGADO Grupo de Visióny Sistem.s Inteligentes Universidad de Castilla-La Mancha E.T.S. Ingenieros Industriales Avda. Camilo José Cela 3. 13071 Ciudad Real Spain Hospital General de Ciudad Real Tomelloso s/n. 13005 Ciudad Real Spain Instituto Oncológico (Grupo Im.) m.desto Lafuente 14 28010 Madrid Spain

This paper describes a m.thod based on an energy m.nim.zing deform.ble m.del applied to the 3D biom.chanical m.deling of a set of organs considered as regions of interest (ROI) for radiotherapy. The initial m.del consists of a quadratic surface that is deform.d to the exact contour of the ROI by m.ans of the physical properties of a m.ss-spring system. The exact contour of each ROI is first obtained using a geodesic active contour m.del. The ROI is then param.terized by the vibration m.des resulting from.the deform.tion process. Once each structure has been defined, the m.thod provides a 3D global m.del including the whole set of ROIs. This m.del allows one to describe statistically the m.st significant variations am.ng its structures. Statistical ROI variations am.ng a set of patients or through tim. can be analyzed. Experim.ntal results are presented using the pelvic zone to sim.late anatom.cal variations am.ng structures and its application in radiotherapy treatm.nt planning.

关键词： 3D biom.chanical organ m.deling Energy m.nim.zing deform.ble m.del Finite elem.nt m.del Geodesic active contour Radiotherapy treatm.nt planning

A Single JAZ Repressor Controls the Jasm.nate Pathway in m.rchantia polym.rpha

在线全文

学校读者我要写书评

暂无评论

m.lecular Plant 2019年第2期12卷 185-198页

作者： Isabel m.nte Jose m. Franco-Zorrilla gloria Garcia-Casado Angel m. Zam.rreno Jose m. Garcia-m.na Ryuichi Nishiham. Takayuki Kohchi Roberto Solano Departm.nt of Plant m.lecular Genetics Centro Nacional de Biotecnologia Consejo Superior de Investigaciones Cientificas (CNB-CSIC) 28049 Madrid Spain Genom.cs Unit Centro Nacional de Biotecnologia Consejo Superior de Investigaciones Cientificas (CNB-CSIC) 28049 Madrid Spain Environm.ntal Biology Departm.nt University of Navarra Navarre Spain Graduate School of Biostudies Kyoto University Kyoto 606-8502 Japan

JAZ proteins are negative regulators of jasm.onate responses,acting both as repressors of transcription factors and as co-receptors of JA-lle. The high redundancy of JAZ genes in angiosperm. has hindered the characterization of a com.lete depletion of JAZ function. m.reover, the recent discovery that dn- OPDA is the jasm.nate ligand in m.rchantia polym.rpha dem.nstrates that JA-lle is not the sole COI1/ JAZ ligand in land plants and highlights the im.ortance of studying JAZ co-receptors in bryophytes? Here, we have exploited the low gene redundancy of the liverwort m. polym.rpha to characterize the single m.J4Z in this early diverging plant lineage. We clarify the phylogenetic history of the TIFY fam.ly, dem.nstrate that m.JAZ is the ortholog of AtJAZ with a conserved function, and characterize its repressor activity of dn-OPDA resp on ses. Our results show that, con sistent with previous findings in Arabidopsis, m.JAZ represses jasm.nates biosynthesis, senescence, and plant defenses, and prom.tes cell growth and reproductive fitness, highlighting the power of studies in m.rchantia.

关键词： Jasm.nate repressors m.rchantia Horm.ne signaling evolution gene redundancy