检索结果-南通市图书馆

CONSTANS alters the circadian clock in Arabidopsis thaliana

Molecular Plant 2024年第8期17卷 1204-1220页

作者： Pedro de los Reyes gloria Serrano-bueno Francisco J.Romero-Campero He Gao Jose M.Romero Federico Valverde Plant Development Group-Institute for Plant Biochemistry and Photosynthesis Consejo Superior de Investigaciones CientificasUniversidad de SevillaSevilleSpain Department of Computer Science and Artificial Intelligence Universidad de SevillaSevilleSpain Department of Plant Developmental Biology Max Planck Institute for Plant Breeding ResearchCologneGermany Department of Plant Biochemistry and Molecular Biology Universidad de SevillaSevilleSpain

Plants are sessile organisms that have acquired highly plastic developmental strategies to adapt to the *** these processes,the floral transition is essential to ensure reproductive success and is finelyregulated by several internal andexternal genetic *** photoperiodic pathway,which controls plant response to day length,is one of the most important pathways controlling *** Arabidopsis photoperiodic flowering,CONSTANS(CO)is the central gene activating the expression of the florigen FLOWERING LOCUS T(FT)in the leaves at the end of a long *** circadian clock strongly regulates Co ***,to date,no evidence has been reported regarding a feedbackloop from the photoperiod pathway back to the circadian *** transcriptional networks,we have identified relevant network motifs regulating the interplay between the circadian clock and the photoperiod *** expression,chromatin immunoprecipitation experiments,and phenotypic analysis allowed us to elucidate the role of Co over the circadian *** with altered cO expression showed a different internal clock period,measured by daily leaf rhythmic *** showed that co upregulates the expression of key genes related to the circadian clock,such as CCA1,LHY,PRR5,and Gl,at the end of a long day by bindingto specific sites on their ***,a high numberof PRR5-repressed target genes are upregulated by CO,and this could explain the phase transition promoted by *** CO-PRR5 complex interacts with the bZiP transcriptionfactor HY5andhelps to localize the complex in the promoters of clock *** together,our results indicate that there may be a feedback loop in which co communicates back to the circadian clock,providing seasonal information to the circadian system.

关键词： CONSTANS circadian clock photoperiod

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Three-dimensional organ modeling based on deformable surfaces applied to radio-oncology

引用

Journal of Zhejiang University-Science C(Computers and Electronics) 2010年第6期11卷 407-417页

作者： gloria bueno Oscar DéNIZ Jesús SALIDO Carmen CARRASCOSA José M. DELGADO Grupo de Visióny Sistemas Inteligentes Universidad de Castilla-La Mancha E.T.S. Ingenieros Industriales Avda. Camilo José Cela 3. 13071 Ciudad Real Spain Hospital General de Ciudad Real Tomelloso s/n. 13005 Ciudad Real Spain Instituto Oncológico (Grupo IMO) Modesto Lafuente 14 28010 Madrid Spain

This paper describes a method based on an energy minimizing deformable model applied to the 3D biomechanical modeling of a set of organs considered as regions of interest (ROI) for radiotherapy. The initial model consists of a quadratic surface that is deformed to the exact contour of the ROI by means of the physical properties of a mass-spring system. The exact contour of each ROI is first obtained using a geodesic active contour model. The ROI is then parameterized by the vibration modes resulting from the deformation process. Once each structure has been defined, the method provides a 3D global model including the whole set of ROIs. This model allows one to describe statistically the most significant variations among its structures. Statistical ROI variations among a set of patients or through time can be analyzed. Experimental results are presented using the pelvic zone to simulate anatomical variations among structures and its application in radiotherapy treatment planning.

关键词： 3D biomechanical organ modeling Energy minimizing deformable model Finite element model Geodesic active contour Radiotherapy treatment planning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computer vision based eyewear selector

引用

Journal of Zhejiang University-Science C(Computers and Electronics) 2010年第2期11卷 79-91页

作者： Oscar DéNIZ Modesto CASTRILLóN Javier LORENZO Luis ANTóN Mario HERNANDEZ gloria bueno Instituto Universitario de Sistemas Inteligentes y Aplicaciones Numéricas en Ingeniería Universidad de Las Palmas deGran CanariaEdificio Central del Parque Científico-Tecnológico 35017 Las Palmas E.T.S. Ingenieros Industriales Universidad de Castilla-La Mancha Campus UniversitarioAvda. Camilo José Cela

The widespread availability of portable computing power and inexpensive digital cameras are opening up new possibilities for retailers in some markets. One example is in optical shops,where a number of systems exist that facilitate eyeglassess election. These systems are now more necessary as the market is saturated with an increasingly complex array of lenses,frames,coatings,tints,photochromic and polarizing treatments,etc. Research challenges encompass Computer Vision,Multimedia andHuman-Computer Interaction. Cost factors are also of importance for widespread product acceptance. This paper describes alow-cost system that allows the user to visualize different glasses models in live video. The user can also move the glasses toadjust its position on the face. The system,which runs at 9.5 frames/s on general-purpose hardware,has a homeostatic modulethat keeps image parameters controlled. This is achieved by using a camera with motorized zoom,iris,white balance,etc. Thisfeature can be specially useful in environments with changing illumination and shadows,like in an optical shop. The system alsoincludes a face and eye detection module and a glasses management module.

关键词： Face detection. Eve detection Perceptual user interfaces Human-computer interaction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Regulation of floral senescence in Arabidopsis by coordinated action of CONSTANS and jasmonate signaling

引用

Molecular Plant 2022年第11期15卷 1710-1724页

作者： gloria Serrano-bueno Pedro de los Reyes Andrea Chini Gabriel Ferreras-Garrucho Víctor Sánchez de Medina-Hernández Marta Boter Roberto Solano Federico Valverde Plant Development Group Institute for Plant Biochemistry and PhotosynthesisCSIC-Universidad de Sevilla41092 SevillaSpain Department of Plant Molecular Genetics Centro Nacional de BiotecnologíaCSIC28049 MadridSpain Crop Science Centre University of CambridgeCambridge CB3 OLE CambridgeUK Gregor Mendel Institute(GMI) Austrian Academy of SciencesVienna BioCenter(VBC)ViennaAustria

In Arabidopsis,photoperiodic flowering is controlled by the regulatory hub gene CONSTANS(CO),whereas floral organ senescence is regulated by the jasmonates(JAs).Because these processes are chronologically ordered,it remains unknown whether there are common regulators of both *** this study,we discovered that CO protein accumulates in Arabidopsis flowers after floral induction,and it displays a diurnal pattern in floral organs different from that in the *** observed that altered CO expression could affect flower senescence and abscission by interfering with JA response,as shown by petal-specific transcriptomic analysis as well as CO overexpression in JA synthesis and signaling *** found that CO has a ZIM(ZINC-FINGER INFLORESCENCE MERISTEM)like domain that mediates its interaction with the JA response repressor JAZ3(jasmonate ZIM-domain 3).Their interaction inhibits the repressor activity of JAZ3,resulting in activation of downstream transcription factors involved in promoting flower ***,we showed that CO,JAZ3,and the E3 ubiquitin ligase COI1(Coronatine Insensitive 1)could form a protein complex in planta,which promotes the degradation of both CO and JAZ3 in the presence of *** together,our results indicate that CO,a key regulator of photoperiodic flowering,is also involved in promoting flower senescence and abscission by augmenting JA signaling and *** propose that coordinated recruitment of photoperiodic and JA signaling pathways could be an efficient way for plants to chronologically order floral processes and ensure the success of offspring production.

关键词： CONSTANS flower senescence jasmonic acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys

引用

World Journal of Pediatrics 2023年第9期19卷 864-872页

作者： Francisco Javier Ruiz‑Ojeda Augusto Anguita‑Ruiz Maria C.Rico Rosaura Leis gloria bueno Luis A.Moreno Mercedes Gil‑Campos Ángel Gil Concepción M.Aguilera Department of Biochemistry and Molecular Biology Ⅱ School of PharmacyUniversity of GranadaGranadaSpain Instituto de Investigación Biosanitaria Ibs.GRANADA 18012 GranadaSpain Institute of Nutrition and Food Technology“JoséMataix” Center of Biomedical ResearchUniversity of GranadaAvda.del Conocimiento S/N.18016 ArmillaGranadaSpain RG Adipocytes and Metabolism Institute for Diabetes and ObesityHelmholtz Center Munich85764 MunichGermany Barcelona Institute for Global Health ISGlobal08003 BarcelonaSpain CIBEROBN (Physiopathology of Obesity and Nutrition CB12/03/30038)Institute of Health Carlos Ⅲ(ISCⅢ)28029 MadridSpain Unit of Investigation in Human Nutrition Growth and Development of Galicia(GALINUT)University of Santiago de Compostela(USC)Santiago de CompostelaSpain Pediatric Nutrition Research Group Institute of Sanitary Research of Santiago de Compostela(IDIS)CHUS-USC15706 Santiago de CompostelaSpain Unit of Pediatric Gastroenterology Hepatology and NutritioPediatric ServiceUniversity Clinical Hospital of Santiago(CHUS)15706 Santiago de CompostelaSpain GENUD Research group Institute of Sanitary Research of Aragón(IIS Aragón)University of ZaragozaZaragozaSpain Instituto Agroalimentario de Aragón(IA2) Universidad de Zaragoza-CITAZaragozaSpain Unit of Pediatric Endocrinology University Clinical Hospital Lozano Blesa50009 ZaragozaSpain Metabolism and Investigation Unit Reina Sofa University HospitalMaimónides Institute of Biomedicine Research of Córdoba(IMIBIC)University of Córdoba14071 CórdobaSpain

Objectives To evaluate whether there is an association between the serum levels of the novel insulin-like adipokine isthmin-1(ISM1)and obesity-related phenotypes in a population of Spanish children and to investigate the plausible molecular alterations behind the alteration of the serum levels of this protein in children with *** The study population is a sub-cohort of the PUBMEP research project,consisting of a cross-sectional population of 119 pubertal children with overweight(17 boys,19 girls),obesity(20 boys,25 girls),and normal weight(17 boys,21 girls).All subjects were classified into experimental groups according to their sex,obesity,and insulin resistance(IR)*** were counted anthropometry,glucose and lipid metabolism,inflammation and cardiovascular biomarkers as well as isthmin-1(ISM1)serum *** population was intended as a discovery population to elucidate the relationship between obesity and ISM1 levels in ***,the study population had blood whole-genome DNA methylation examined,allowing deepening into the obesity–ISM1 molecular *** Higher serum ISM1 levels were observed in boys with obesity than in normal weight(P=0.004)and overweight(P=0.007)***1 serum levels were positively associated with body mass index(BMI)Z-score(P=0.005)and fat mass(P=0.058)and negatively associated with myeloperoxidase(MPO)(P=0.043)in *** we did not find associations between ISM1 serum levels and metabolic outcomes in girls,which may indicate a putative sexual dimorphism,fat mass was positively associated in all children,including boys and girls(P=0.011).DNA methylation levels in two-enhancer-related CpG sites of ISM1(cg03304641 and cg14269097)were associated with serum levels of ISM1 in *** ISM1 is associated with obesity in boys at the pubertal stage,elucidating how this protein might be of special relevance as a new biomarker of obesity in *** studies including a longitudina

关键词： Children Epigenetics Isthmin-1 Obesity Puberty

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

局部晚期乳腺癌患者双时相18F-FDGPET/CT显像的纹理特征及基于标准摄取值的相关参数

引用

中华核医学与分子影像杂志 2018年第6期38卷 454-455页

作者：唐军 Ana María Garcia-Vicente David Molina Julián Pérez-Beteta Mariano AmoSalas Alicia Martínez-González gloria bueno María Jesús Tello-Galán Angel Soriano-Castrejón 上海交通大学医学院附属苏州九龙医院核医学科 Nuclear Medicine Department University General Hospital Ciudad RealSpain

目的探讨双时相18F-脱氧葡萄糖(FDG)PET/CT显像对纹理特征分析和基于标准摄取值(SUV)的相关参数的影响及其相互关系。方法该前瞻性研究纳入56例局部晚期乳腺癌(LABC)患者,患者均行常规18F-FDG PET/CT显像(注药后1 h显像,PET-1)和延迟显... 详细信息

目的探讨双时相18F-脱氧葡萄糖(FDG)PET/CT显像对纹理特征分析和基于标准摄取值(SUV)的相关参数的影响及其相互关系。方法该前瞻性研究纳入56例局部晚期乳腺癌(LABC)患者,患者均行常规18F-FDG PET/CT显像(注药后1 h显像,PET-1)和延迟显像(注药后3 h显像,PET-2)。图像经软件分割后计算得到基于SUV的相关参数[最大SUV(SUVmax)、平均SUV(SUVmean)和SUV峰值(SUVpeak)]、代谢肿瘤体积(MTV)和病灶糖酵解总量(TLG)。同时计算18项三维纹理特征分析参数,其中包括行程长度矩阵(RLM)特征、共生矩阵(CM)特征和能量特征(空间能量和总能量)。研究PET-1和PET-2上述参数的差别。结果 PET-1、PET-2间基于SUV的相关参数和MTV的差异有统计学意义,与PET-1相比,PET-2的SUV相关参数更高,但MTV更低。PET-1、PET-2间有明显差异的纹理特征分析参数为短行程增强(RSE)、低灰度行程增强(LGLRE)、短行程高灰度增强(SRHGLE)、行程百分比(RP)、长行程增强(LRE)、灰度非均匀性(GLNU)、同质性(HOM)和差异性(DIS)。纹理特征分析参数与MTV和TLG相关。结论双时相18F-FDG PET/CT显像图像的纹理特征分析参数间有明显差异。因此,18F-FDG PET/CT显像时应考虑到代谢特征的动态变化,即延迟显像时肿瘤组织表现出的异质性更强,且瘤体越大异质性越强。

关键词：双时相18F-FDG PET/CT 乳腺肿瘤肿瘤异质性纹理特征

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：