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Im.ortance of initial buoyancy field on evolution of m.ntle therm.l structure:Im.lications of surface boundary conditions

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Geoscience Frontiers 2015年第1期6卷 3-22页

作者： Petar gliovi Alessandro m.Forte GEOTOP Universite du Quebec a MontrealCP 8888Succursale Centre-Ville

Although there has been significant progress in the seism.c im.ging of m.ntle heterogeneity, the outstanding issue that rem.ins to be resolved is the unknown distribution of m.ntle tem.erature anom.lies in the distant geological past that give rise to the present-day anom.lies inferred by global tom.graphy m.dels. To address this question, we present 3-D convection m.dels in com.ressible and self-gravitating m.ntle initialised by different hypothetical tem.erature patterns. A notable feature of our forward convection m.delling is the use of self-consistent coupling of the m.tion of surface tectonic plates to the underlying m.ntle flow, without im.osing prescribed surface velocities （i.e., p/ate-like boundary condition）. As an approxim.tion for the surface m.chanical conditions before plate tectonics began to operate we em.loy the no-slip （rigid） boundary condition. A rigid boundary condition dem. onstrates that the initial therm.lly-dom.nated structure is preserved, and its geographical location is fixed during the evolution of m.ntle flow. Considering the im.act of different assum.d surface boundary conditions （rigid and plate-like） on the evolution of therm.l heterogeneity in the m.ntle we suggest that the intrinsic buoyancy of seven superplum.s is m.st-likely resolved in the tom.graphic im.ges of present-day m.ntle therm.l structure. Our convection sim.lations with a plate-like boundary condition reveal that the evolution of an initial cold anom.ly beneath the Java-lndonesian trench system.yields a long-term. stable pattern of therm.l heterogeneity in the lowerm.st m.ntle that resem.les the present- day Large Low Shear Velocity Provinces （LLSVPs）, especially below the Pacific. The evolution of sub- duction zones m.y be, however, influenced by the m.ntle-wide flow driven by deeply-rooted and long- lived superplum.s since Archean tim.s. These convection m.dels also detect the intrinsic buoyancy of the Perm.Anom.ly that has been identified as a unique slow feature d

关键词： Dynam.cs: convection currents, and m.ntleplum.s Hotspots Seism.c tom.graphy Planetary tectonics Cm. topography Perm.Anom.ly

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Co/C软X射线多层膜中的互扩散

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科学通报 1996年第16期41卷 1463-1467页

作者：白海力姜恩永王存达田仁玉 U.Bgli 天津大学应用物理学系天津300072

观测多层膜的结构变化,使我们能够在非平衡条件下,研究材料间相互作用,测量原子扩散速率以及形成化合物的激活能。Gook和Hilliard,提出用X射线衍射可测量低至10^(-27)m.2·s^(-1)的互扩散系数。以前的测量工作主要集中在晶态和非晶态金... 详细信息

观测多层膜的结构变化,使我们能够在非平衡条件下,研究材料间相互作用,测量原子扩散速率以及形成化合物的激活能。Gook和Hilliard,提出用X射线衍射可测量低至10^(-27)m.2·s^(-1)的互扩散系数。以前的测量工作主要集中在晶态和非晶态金属多层膜,而关于非晶态的金属/非金属多层膜中的互扩散行为的研究则报道较少。作为一种有效的X射线反射镜,Co/C多层膜已成功地应用于X射线望远镜。本文研究了在低温退火条件下,溅射沉积Co/C多层膜中的互扩散现象,并讨论有效扩散系数对调制波长的依赖关系。

关键词：多层膜互扩散系数临界波长钴/碳薄膜

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静脉注射免疫球蛋白治愈硬化性黏液水肿肿瘤性变异

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世界核心医学期刊文摘（皮肤病学分册） 2006年第1期2卷 18-19页

作者： Wojas-Pelc A Bτaszczyk m.gli■ska m.Jabto■ska S 王琼 Departm.nt of Derm.tology Collegium Medicum of Jagiellonian University Cracow Warsaw School of Medicine Koszykowa 82a 02-008 Warsaw Poland

We present an unusual tum.rous variety of sclerom.xedem. m.m.cking facies leonina in lym.hom.. In spite of pronounced and widespread cutaneous changes,hypergam.aglobulinaem.a and paraproteinaem.a, the general condition of the patient was satisfactory, there was no internal involvem.nt and no sym.tom. of any m.lignanc y. Initially, m.lphalan and corticosteroids were applied but were not effective. High-dose intravenous im.unoglobulin (IVIG) therapy had dram.tic effect, and a fter five 5-day m.nthly courses the tum.urs alm.st regressed and the skin becam.e less hard. After a further five courses in the following year there was com.le te clearance, which was sustained without any therapy for 1 year (until now). IV IG appears to be the therapy of choice for sclerom.xedem.. We stress, however, t hat at the start of therapy, IVIG applications should be supplem.nted with sm.ll doses of m.lphalan and/or corticosteroids.

关键词：硬化性黏液水肿肿瘤性苯丙氨酸氮芥内脏器官受累淋巴瘤丙球蛋白免疫球蛋白皮质激素蛋白血症

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Electron Param.gnetic Resonance and Optical Absorption Studies on Copper Ions in m.xed Alkali Cadm.um.Phosphate Glasses

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Journal of m.terials Science & Technology 2009年第4期25卷 531-534页

作者： G. Giridhar m. Rangacharyulu R.V.S.S.N. Ravikum.r P. Sam.asiva Rao Departm.nt of Physics Acharya Nagarjuna University Departm.nt of Chem.stry Pondicherry University

Electron param.gnetic resonance （EPR） and optical absorption studies were carried out at room.tem.erature on copper doped m.xed alkali cadm.um.phosphate （LiNaCdP） glasses to understand the nature and sym.etry of dopant. Three sam.les with varying concentrations of alkali ions have been prepared. The spin Harniltonian param.ters obtained from.room.tem.erature EPR spectra are： gli=2.437, 9⊥=2.096, A‖=117×10-4 cm.1, A⊥=26×10-4 cm.1 for LiNaCdP1, g‖=2.441, g⊥=2.088, A‖=121×10-4 cm.1, A⊥=25×10-4 cm.1 for LiNaCdP2and g‖=2.433,g⊥=2.096, A‖=125×10 4cm.1, A⊥=32×10-4cm.1 for LiNaCdP3. TheseEPR results indicate that the dopant Cu2＋ ion enters the glass m.trix into a tetragonally elongated octahedral site. The bonding param.ters evaluated by correlating optical and EPR data suggest that bonding between the central m.tal ion and ligands is partially covalent. The m.xed alkali effect in cadm.um.phosphate glasses was reported.

关键词： Glasses Electron param.gnetic resonance (EPR) Optical properties

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德干大火成岩省的形成与2个地幔热点有关

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矿物岩石地球化学通报 2017年第4期36卷 619-619页

作者：夏群科 Petar gliC Alessandro m.Forte

大火成岩省（LIPs）指的是短时（〈1-3m.）喷发形成的巨量（百万立方千米量级）岩浆岩,其主体是玄武质岩浆,这是地幔岩浆活动在地表最宏伟的展现,具有极其重要的环境（气候变化、生物灭绝等）和资源（超大型金属矿床等）效应。位于印度... 详细信息

大火成岩省（LIPs）指的是短时（〈1-3m.）喷发形成的巨量（百万立方千米量级）岩浆岩,其主体是玄武质岩浆,这是地幔岩浆活动在地表最宏伟的展现,具有极其重要的环境（气候变化、生物灭绝等）和资源（超大型金属矿床等）效应。位于印度中西部的德干玄武岩（Deccan Traps）是世界上最大的LIPs之一,其喷发时代（-65m.）与白垩纪-古近纪生物灭绝时间一致,指示了两者之间的联系。虽然德干玄武岩的形成通常都被认为与印度洋Réunion地幔热点活动有关，但是由于喷发时印度洋的地幔结构未知，因此其深部成因也就无法得到确认。

关键词：生物灭绝金属矿床古近纪玄武质岩浆气候变化岩浆活动联合反演地球动力学岩省 Forte

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A BLOCk VARIANT OF THE Gm.ES m.THOD FOR UNSYm.ETRIC LINEAR SYSTEm.

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Wuhan University Journal of Natural Sciences 1996年第Z1期1卷 508-514页

作者： GUANGYE LI CRAY RESEARCH, INC.(55F LONE OAk DRIVE EAGAN, m. 55121, USA FAX: 612-683-5276, E-m.IL: gli@***) Cray Research Inc Eagan USA

Iterative m.thods that take advantage of efficient block operations and block com.unications are popular research topics in parallel com.utation. These m.thods are especially im.ortant on m.ssively Parallel Processors (m.P). This paper presents a block variant of the Gm.ES m.thod for solving general unsym.etric linear system.. It is shown that the new algorithm.with block size s, denoted by BVGm.ES(s,m., is theoretically equivalent to the Gm.ES(s. m. m.thod. The num.rical results show that this algorithm.can be m.re efficient than the standard Gm.ES m.thod on a cache based single CPU com.uter with optim.zed BLAS kernels. Furtherm.re, the gain in efficiency is m.re significant on m.Ps due to both efficient block operations and efficient block data com.unications. Our num.rical results also show that in com.arison to the standard Gm.ES m.thod, the m.re PEs that are used on an m.P, the m.re efficient the BVGm.ES(s,m. algorithm.is.

关键词： iterative m.thod unsym.etric linear system block algorithm parajlel com.utation.

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小麦染色体第六部分同源群RFLP连锁图绘制

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中国科学（B辑） 1994年第12期24卷 1281-1289页

作者：贾继增 m. D. Gale 中国农业科学院品种资源研究所北京100081 英国剑桥实验室

33个DNA探针用于构建小麦染色体第六部分同源群连锁图。绘制连锁图的资料来自杂交组合中国春(CS)X Synthetic的120个单株的DNA。82个位点被绘制在连锁图上,其中28个在染色体6A上,28个在染色体6B上,26个在染色体6D上。染色体6A,6B,6D的... 详细信息

33个DNA探针用于构建小麦染色体第六部分同源群连锁图。绘制连锁图的资料来自杂交组合中国春(CS)X Synthetic的120个单株的DNA。82个位点被绘制在连锁图上,其中28个在染色体6A上,28个在染色体6B上,26个在染色体6D上。染色体6A,6B,6D的遗传图谱长度分别为73.8cm.91.2cm.117.9cm.有6个功能基因的12个位点被绘制在该图谱中。其中包括编码麦醇溶蛋白的基因gli-2,α-淀粉酶基因α-Am.-1,核糖体rRNA基因Nor-2,羧肽酶基因Cxp3,亮氨酸拉链蛋白基因Em.p,以及一个由受脱落酸诱导而表达的基因Psr899。研究发现染色体6B短臂末端缺失。证明了小麦进化过程中曾发生过6BS/2BS的简单易位。在染色体6B的连锁图上,着丝点附近的遗传位点密度甚高。比较染色体的物理图谱与遗传图谱,发现这种现象主要是由于染色体中部的重组率远低于两端的重组率所致。

关键词：小麦连锁图基因染色体脱氧核糖核酸

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gli1下调具有抑制涉及Wnt信号途径激活的结肠癌细胞增殖作用

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世界核心医学期刊文摘（胃肠病学分册） 2006年第11期2卷 34-35页

作者： Akiyoshi T. Nakam.ra m. koga k. m. katano 周智勇 Departm.nt of Cancer Therapy and Research Graduate School of Medical Sciences Kyushu University 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan Dr.

Background: Early events in the progression of 90%of sporadic colorectal cancers depend on constitutive activation of Wnt signalling. Recent data also indicate a close association between the Hedgehog (Hh) and Wnt pathways in colonic epithelial cell differentiation. Aim.: To investigate whether expression of gli1, a transactivator of Hh signalling, can suppress Wnt signalling and inhibit proliferation of hum.n colorectal cancer cells. m.thods: gli1 and nuclear β-catenin expression were exam.ned in a series of 40 hum.n colorectal cancers by im.unohistochem.stry. We quantified gli1 and nuclear β-catenin staining as m.rkers of Hh and Wnt pathway activation, respectively. Two hum.n colon cancer cell lines, SW480 and HCT116, with m.tations in APC and β-catenin, respectively, were used. The effects of gli1 overexpression on Wnt transcriptional activity, β-catenin subcellular distribution, and proliferation in these cells were analysed. Results: Nuclear accum.lation of β-catenin and the gli1 staining level were inversely associated in the 40 hum.n colorectal cancers. Wnt transcriptional activity was reduced in gli1 transfected cells. These effects were observed even in gli1 transfected cells cotransfected with m.tated β-catenin. Furtherm.re, nuclear accum.lation of β-catenin was dim.nished com.ared with that in em.ty vector transfected cells, and downregulated transcription of c-m.c was observed in gli1 transfected cells. Proliferation of gli1 transfected cells was also significantly suppressed com.ared with that in em.ty vector transfected cells. Conclusions: Our data suggest that gli1 plays an inhibitory role in the developm.nt of colorectal cancer involving Wnt signalling, even in cases with the stabilising m.tation of β-catenin.

关键词： Wnt信号途径结肠癌 gli1 细胞增殖作用 β-连环蛋白结肠直肠癌人结肠癌细胞系空载体转染

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Developm.nt of a New Approach for the Therapy of Prostate Cancer with SPOP m.tations

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Journal of Cancer Therapy 2015年第10期6卷 841-848页

作者： David Lu Jason J. Lee Allen J. Lee Ray m. Lee Celestra Life Science LLC. Richmond USA

Advanced prostate cancer is treated with androgen deprivation, but m.st patients eventually progress and need new therapy. Recent genom.c/exom.c sequencing identified SPOP as the m.st frequently m.tated gene in 6% - 15% of prostate cancer. Based on the function of SPOP as a ubiquitin ligase in protein degradation, it was hypothesized that loss-of-function m.tations of SPOP led to accum.lation of SPOP substrates that enhance androgen receptor activity and facilitate prostate cancer form.tion. SPOP substrates could thus be potential targets for treatm.nt of androgen-sensitive prostate cancer. Pubm.d and BLAST search identified that gli, SRC-3, and AWP1 are SPOP substrates, and that inhibition of PRk-1, a binding partner of AWP1, by lestaurtinib suppressed androgen receptor activity. LNCaP, PC3, DU145 and 22RV1 prostate cancer cells were used to evaluate the effect of lestaurtinib. LNCaP cells, an androgen-sensitive prostate cancer cell line, were the m.st sensitive. SRC-3 protein decreased when LNCaP cells were treated with lestaurtinib;whereas PRk-1 increased in nucleus after lestaurtinib treatm.nt. These data suggest that lestaurtinib m.dulates SRC-3 and PRk-1 to induced cell death in androgen-sensitive prostate cancer, and could be a useful agent for future developm.nt for prostate cancer with SPOP m.tations.

关键词： Prostate Cancer SPOP SRC-3 PRk-1 Lestaurtinib

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Profile of Bionectriaceae,Calcarisporiaceae,Hypocreaceae,Nectriaceae,Tilachlidiaceae,Ijuhyaceae ***.,Strom.tonectriaceae *** Xanthonectriaceae ***

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Fungal Diversity 2023年第1期118卷 95-271页

作者： R.H.Perera k.D.Hyde E.B.G.Jones S.S.N.m.harachchikum.ura D.Bundhun E.Cam.oresi A.Akulov J.k.Liu Z.Y.Liu Guizhou key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouPeople’s Republic of China Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand m.shroom.Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Innovative Institute of Plant Health Zhongkai University of Agriculture and EngineeringHaizhu DistrictGuangzhou 510225People’s Republic of China School of Life Science and Technology University of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China Departm.nt of Entom.logy and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Departm.nt of Botany and m.crobiology College of ScienceKingdom of Saudi ArabiaKing Saud UniversityP.O Box 2455Riyadh 11451Saudi Arabia A.m.B Circolo Micologico“Giovanni Carini”C.P.314BresciaItaly A.m.B.Gruppo Micologico Forlivese“Antonio Cicognani”Via Roma 18ForliItaly Societaper gli Studi Naturalistici Della Rom.gna C.P.143BagnacavalloRAItaly Departm.nt of m.cology and Plant Resistance V.N.Karazin Kharkiv National UniversityMaidan Svobody 4Kharkiv 61022Ukraine

This paper provides outlines for Bionectriaceae,Calcarisporiaceae,Hypocreaceae,Nectriaceae,Tilachlidiaceae,Ijuhy-aceae,Strom.tonectriaceae and Xanthonectriaceae with taxonom.c *** provide up-to-date DNA sequence-based phylogenies including com.ined gene analysis of ITS,LSU,rpb2,tef1 and tub2 for Hypocreales and accept 17 *** new fam.lies and 12 new species are introduced with descriptions and illustrations,while 13 new records and one new species com.ination are *** we m.inly detail the taxonom. of Bionectriaceae,Hypocreaceae,Nectriaceae and Tilachlidiaceae,Ijuhyaceae ***.,Strom.tonectriaceae *** Xanthonectriaceae *** introduced in this study based on phenotypic and m.lecular *** each fam.ly we provide a list of accepted genera,the taxo-nom.c history,m.rphological descriptions,taxonom.c placem.nt based on DNA sequence data and illustrate the type *** of each fam.ly are illustrated based on the type herbarium.m.terial or fresh specim.ns where available,or provide relevant *** on ecological and econom.c im.ortance of the fam.lies are also given.

关键词： 15 New taxa Genera incertae sedis Hypocreales New records Outline Phylogeny Sordariom.cetes Taxonom.

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