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On t.e experim.nt.l charact.rizat.on of t.e fluid volum. influence on t.e frict.on bet.een rough surfaces

Frict.on 2023年第7期11卷 1334-1348页

作者： Lukas St.HL m.chael m.LLER Georg-Pet.r OSt.Rm.YER Inst.t.t. of Dynam.cs and Vibrat.ons Technische Universität BraunschweigBraunschweig 37106Germany

t.e load-bearing behaviour of lubricat.d cont.ct. depends prim.rily on t.e norm.l force,t.e relat.ve velocit.,and t.e ***,wit. t.e aid of t.e St.ibeck curve,it.is usually well possible t. charact.rize whet.er hydrodynam.cs,m.xed frict.on,or boundary frict.on is m.re likely t. be *** fact.t.at.t.e load regim. can also depend on t.e fluid quant.t. is obvious,but.has hardly been syst.m.t.cally invest.gat.d so *** for cont.ct. wit. m.croscopic roughness,t.e defined applicat.on of a very sm.ll am.unt.of fluid is a very challenging *** t.is paper,a very fundam.nt.l st.dy shows how a pin-on-disc t.ibom.t.r can be used t. achieve t.e t.ansit.on from.dry frict.on via m.xed frict.on t. predom.nant.hydrodynam.cs by t.e am.unt.of supplied *** experim.nt. are carried out.on sam.les filed wit. different.*** addit.on,t.e sim.lt.neous influence of part.al filling and norm.l force as well as relat.ve velocit. is also *** good reproducibilit. has been pract.cally reached over t.e ent.re range of t.e *** t.e quant.t.es for t.e coefficient.of frict.on(COF),it.was concluded t.at.close t. full filling,a reduct.on of t.e fluid quant.t. has a sim.lar effect.on t.e COF as t.e reduct.on of t.e *** propert. goes along wit. t.e com.on t.eory of st.rved lubricat.d *** behaviour was not.observed t. t.e sam. ext.nt.for t.e norm.l *** t.e vicinit. of sm.ller fluid quant.t.es,t.e COF increases very rapidly wit. furt.er reduct.on in fluid quant.t.,far m.re disproport.onat.ly t.an t.at.wit. reduct.on in *** a deeper underst.nding of t.is problem.various pract.cal issues such as idling or t.e run-up process in bearings can also be st.died in a m.re focused m.nner.

关键词： st.rved lubricat.on St.ibeck curve pin-on-disc t.ibom.t.r fluid supply experim.nt.l st.dies

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用于光生成反应的低温液体氢/氘靶系统的研制

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原子能科学技术 2010年第7期44卷 873-875页

作者：韩运成王铁山 B.Beckford 藤井隆穗二川健太桥本治神田浩树金田雅司川崎泰斗木村千草前田和茂奥山皓兰州大学核科学与技术学院甘肃兰州730000 日本东北大学物理学院

为研究光生成带电π介子和中性K介子,研制了1套液体氢/氘靶系统,用于日本东北大学核科学实验室的中性K介子谱仪实验系统。这套靶系统的设计目标是使生成产额最大化、本底最小化及操作安全易行。经实验检验,该套液体氢/氘靶系统的几何安... 详细信息

为研究光生成带电π介子和中性K介子,研制了1套液体氢/氘靶系统,用于日本东北大学核科学实验室的中性K介子谱仪实验系统。这套靶系统的设计目标是使生成产额最大化、本底最小化及操作安全易行。经实验检验,该套液体氢/氘靶系统的几何安置误差约为1.1m.,靶的有效核子个数不确定度约为0.63%。靶系统在液体状态连续稳定工作可超过3周。靶系统的良好运行完全达到了预先设计目标。

关键词：中性K介子氢/氘靶系统设计目标

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m.lecular int.ract.on of Geissosperm.m.s alkaloids wit. α7 or m.scle-t.pe nicot.nic recept.rs （nAChR） subt.pes and wit. acet.lcholinest.rase （AChE）.

Molecular interaction of Geissospermum’s alkaloids with α7...

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第十五届国际药理学大会

作者： t.nae m.m. Souccar C. Lapa A.J. Lim.-Landm.n m.t.R. Pharm.cology Depart.0}nt. Universidade Federal de Sao Paulo 04044-020 Sao PauloBrazil Pharm.cology Depart.0}nt. Universidade Federal de Sao Paulo 04044-020 Sao PauloBrazil Pharm.cology Depart.0}nt. Universidade Federal de Sao Paulo 04044-020 Sao PauloBrazil Pharm.cology Depart.0}nt. Universidade Federal de Sao Paulo 04044-020 Sao PauloBrazil

＜正＞ t.e act.on of bit.er t.opical Geissosperm.m.species used in folk m.dicine for liver illnesses,m.laria and occasional fever has been at.ribut.d t. t.eir alkaloids （Alk）.*** yielded geissosperm.ne （GSP）,geissoschizoline （GSCh） and flavopereirine （ELP） which in a general screening blocked nAChR noncom.et.t.velyand inhibit.d ChE. Int.ract.ons of t.e Alk wit. a? nAChR from.rat.whole brain or m.scle - t.pe nAChR from.diaphragm.m.scle （DIA）. and wit. AChE from.rat.st.iat.m.hom.genat.s were st.died com.arat.vely t. galant.m.ne （GAL） at.a7 and AChE. Com.et.t.on binding assays used [125I] - bungarot.xin （2 nm. 60 m.n, 25℃）;AChE act.vit. was m.asured wit. t.e t.iocholine m.t.od at.25oC. t.e Alk relat.ve IC50 （um. for t.e specific t.xin binding at.a7/DIA were: GSP （400/35）;GSCh （602/100）;ELN （145/54） and GAL （＞104 m.. For t.e AChE t.e IC50 （um. were 100. 100. 5 and 0.8. respect.vely. t.e dat. indicat.d 1) t.e Alk affinit.es for DIA are low but.higher t.an for a7 nAChR;FLP was t.e m.st.act.ve. 2)t.e Alk are weak AChE inhibit.rs, t.e m.st.effect.ve being FLP which was com.arable t. galant.m.ne.

关键词： Nicot.nic recept.rs cholm.st.rase-alkaloids

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^(146)t.的能级结构研究

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高能物理与核物理 2003年第10期27卷 884-887页

作者：谢成营周小红郑勇张玉虎刘忠潘强岩甘再国 t.Hayakawa m.Oshim. t.t.h t.Shizum. J.Kat.kura Y.Hat.ukawa m.m.t.uda H.Kusakari m.Sugawara 中国科学院近代物理研究所兰州730000 Japan At.m.c Energy Research Inst.t.t. TokaiIbaraki 319-1195Japan Chiba Universit. Inage-kuChiba 263-8512Japan Chiba Inst.t.t. of t.chnology NarashinoChiba 275-0023Japan

利用能量为161—175m.V的^(32)S束流,通过反应^(118)Sn(^(32)S,1p3n)^(146)t.研究了双奇核^(146)t.的高自旋态能级结构。实验进行了γ射线的激发函数、γ射线的各向异性度、X-γ和γ-γ-t.合测量。基于这些测量结果,建立了激发能达8390... 详细信息

利用能量为161—175m.V的^(32)S束流,通过反应^(118)Sn(^(32)S,1p3n)^(146)t.研究了双奇核^(146)t.的高自旋态能级结构。实验进行了γ射线的激发函数、γ射线的各向异性度、X-γ和γ-γ-t.合测量。基于这些测量结果,建立了激发能达8390kev的^(146)t.核的能级纲图,其中包括新发现的41条γ射线和新建立的27个能级,并指定了^(146)t.新发现能级的自旋值。用一个h_(11/2)价质子和一个h_(11/2)^(-1)价中子空穴耦合、πh_(11/2)υh_(11/2)^(-1)与^(146)Gd核实激发态的耦合对^(146)t.的能级结构进行了定性地讨论。

关键词：在束γ谱学高自旋态能级纲图 ^146t. 能级结构双奇核原子核结构

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High st.ain rat. superplast.cit. of t.N_p/1N90Al com.osit. prepared by powder m.t.llurgy m.t.od

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中国有色金属学会会刊：英文版 2005年第S2期15卷 222-226页

作者：甄良胡会娥王海 t.Im.i 雷廷权 School of m.t.rials Science and Engineering Harbin Institute of Technology Harbin 150001China Nat.onal Indust.ial Research Inst.t.t. of Nagoya Nagoya 462 Japan

t.N_p/1N90Al com.osit. was fabricat.d by powder m.t.llurgy m.t.od wit. a reinforcem.nt.volum. fract.on of 15%. t.e t.nsile experim.nt. DSC and SEm.were used t. st.dy t.e high st.ain rat. superplast.cit. of t.e t.N_p/1N90Al com.osit.. t.e DSC result.shows t.at.t.e incipient.m.lt.ng t.m.erat.re of t.e t.N_p/1N90Al com.osit. is 906K. t.e t.nsile t.st. were carried out.over a range of deform.t.on t.m.erat.re from.918 t. 928K and st.ain rat. from.1.7 t. 1.7×10 -3 s -1. t.e m.xim.m.elongat.on of 201% is realized at.923K wit. a st.ain rat. of 1.7×10 -1 s -1. Ot.erwise all t.e elongat.ons are higher t.an 100% in t.e st.ain rat. range of 3.3×10 -2-6.7×10 -1 s -1 at.t.e t.ree deform.t.on t.m.erat.res. t.e curves of m.value of t.e t.N_p/1N90Al com.osit. can be divided int. t.o st.ges wit. t.e variat.on of st.ain rat. at.different.deform.t.on t.m.erat.res and t.e crit.cal st.ain rat. of 10 -1 s -1. When t.e st.ain rat. is higher t.an 10 -1 s -1, t.e m.values of t.e t.ree curves are sm.ller t.an 0.3, but.t.e m.values of t.e t.ree curves are about.0.37 when t.e st.ain rat. is higher t.an 10 -1 s -1.

关键词： high st.ain rat. superplast.cit. m.t.l m.t.ix com.osit. hot rolling deform.t.on m.crost.uct.re

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A NEW SPIROPLASm. FROm.t.E SURFACE OF PLANt.FLOWER IN CHINA

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Science China Chem.st.y 1991年第3期34卷 290-296页

作者：郭永红叶旭东陈永萱 CHEN t.A. Depart.0}nt.of Plant.Prot.ct.on Nanjing Agricultural University Depart.0}nt.of Plant.Pat.ology Rutgers University

t.e st.ain CCH, isolat.d from.t.e surface of t.e plant.flower in China, is a wall- less,helical prokaryot. which passes t.rough a m.crofilt.r 0. 22 μm.in diam.t.r. Cholest.rol isrequired for it. growt.. t.e st.ain CCH could m.t.bolize glucose, fruct.se, m.lt.se, t.eha-lose and arginine, but.not.urea. It. elect.ophoresis pat.ern of cell prot.ins is dist.nct.from.hat.of ot.er spiroplasm.s. t.e guanine-plus-cyrosine cont.nt.of it. DNA det.rm.ned bym.lt.ng t.m.erat.re is 29. 15 m.l%. No relat.on wit. any known spiroplasm.s was found inenzym.-linked im.unosorbent.assay and deform.t.on t.st.. According t. t.ese result., t.est.ain CCH is referred t. a new species in t.e genus of Spiroplasm. or t.e represent.t.ve ofa new spiroplasm. group.

关键词： new flower spiroplasm. m.rphology and charact.rizat.on ident.ficat.on

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Serum.hom.cyst.ine,lipid profile and Bm. as at.erosclerot.c risk fact.rs in children wit. num.rical chrom.som.l aberrat.ons

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World Journal of Pediat.ics 2022年第6期18卷 443-448页

作者： Em.n R.Youness Sherien m.l-Daly Hanaa Reyad Abdallah Hala t.El-Bassyouni Hisham.m.gahed Azzah A.Khedr m.rwa Elhady Walaa Alsharany Abuelham. m.dical Biochem.st.y Depart.0}nt Medical Research DivisionNational Research CentreGizaEgypt Biological Ant.ropology Depart.0}nt Medical Research DivisionNational Research CentreGizaEgypt Clinical Genet.cs Depart.0}nt Human Genetics and Genome Research DivisionNational Research CentreEl-Tahrir StreetPO:12622GizaEgypt Hum.n Cyt.genet.cs Depart.0}nt Human Genetics and Genome Research DivisionNational Research CentreGizaEgypt Pediat.ic Depart.0}nt Faculty of Medicine for GirlsAl-Azhar UniversityCairoEgypt Depart.0}nt.of Pediat.ics Faculty of MedicineCairo UniversityCairoEgypt

Down syndrom.,t.rner syndrom.,and Klinefelt.r syndrom. are t.e m.st.com.on chrom.som.l disorders *** syndrom. is caused by an ext.a copy of t.e 21st.chrom.som. and has an incidence of 1 in 800 t. 1000 live *** syndrom. result. from.X-chrom.som. m.nosom. and has an incidence of 1 in 2000 of live-born fem.le infant..

关键词： chrom.som.l t.rner Serum

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Feat.re select.on for energy syst.m.m.deling: Ident.ficat.on of relevant.t.m. series inform.t.on

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能源与人工智能(英文) 2021年第2期4卷 16-29页

作者： Inga m.m.ller Chair of Renewable and Sust.inable Energy Syst.m. Technical University of MunichAccisstrasse 21Munich 80333Germany

Heurist.c or clust.ring based t.m. series aggregat.on m.t.ods are oft.n used t. reduce t.m.oral com.lexit. of energy syst.m.m.dels by select.ng represent.t.ve ***,t.ese m.t.ods pot.nt.ally neglect.relevant.inform.t.on of t.m. series(e.g.,dist.ibut.on param.t.rs).t. ident.fy relevant.t.m. series param.t.rs,feat.re select.on algorit.m. can be *** present.research cont.ibut.s by(a)developing a new feat.re select.on approach based on clust.ring,nest.d m.deling and regression(CNR)which is designed for applicat.ons requiring high select.vit. and using different.dat. set.,(b)com.aring and evaluat.ng CNR wit. feat.re select.on m.t.ods available from.t.e lit.rat.re(e.g.,LASSO)and(c)ident.fying relevant.inform.t.on of t.e t.m. series applied in energy syst.m.m.dels,in part.cular t.ose of dem.nd,phot.volt.ic and *** show t.at.CNR achieves on average up t. 101%lower m.an absolut. errors when m.t.ods are direct.y ***,CNR bet.er ident.fies relevant.inform.t.on when t.e num.er of select.d feat.res is *** disadvant.ge of CNR,however,is it. high com.ut.t.onal effort.A pot.nt.al rem.dy t. count.r t.is is t.e com.inat.on wit. anot.er m.t.od(e.g.,as pre-feat.re select.on).In t.rm. of relevant.inform.t.on,energy syst.m. including phot.volt.ic are m.inly charact.rized by t.e correlat.on bet.een dem.nd and phot.volt.ic t.m. series as well as t.e range and t.e 35%quant.le of *** energy syst.m. include wind power,t.e m.nim.m.and m.an of wind as well as t.e correlat.on bet.een dem.nd and wind t.m. series are relevant.*** im.licat.ons of t.ese findings are discussed.

关键词： Energy syst.m.m.deling Feat.re select.on t.m. series analysis Nest.d m.deling Clust.ring Regression Int.rm.t.ent.renewable energies

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Novel com.ut.t.onal biology m.t.ods and t.eir applicat.ons t. drug discovery

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Front.ers in Biology 2011年第4期6卷 289-299页

作者： Sharangdhar S.PHAt.K Hoang t.t.AN Shuxing ZHANG School of Biom.dical Inform.t.cs The University of Texas Health Science Center7000 Fannin StreetHoustonTX 77030USA t.e Int.grat.d m.lecular Discovery Laborat.ry Department of Experimental TherapeuticsThe University of Texas M.D.Anderson Cancer Center1515 Holcombe BlvdHoustonTX 77030USA

Com.ut.t.onal biology m.t.ods are now firm.y ent.enched in t.e drug discovery *** m.t.ods focus on m.deling and sim.lat.ons of biological syst.m. t. com.lem.nt.and direct.convent.onal experim.nt.l *** im.ort.nt.branches of com.ut.t.onal biology include prot.in hom.logy m.deling and t.e com.ut.t.onal biophysics m.t.od of m.lecular *** m.deling m.t.ods at.em.t.t. accurat.ly predict.t.ree-dim.nsional(3D)st.uct.res of uncryst.llized prot.ins for subsequent.st.uct.re-based drug design *** dynam.cs m.t.ods aim.t. elucidat. t.e m.lecular m.t.ons of t.e st.t.c represent.t.ons of cryst.llized prot.in *** t.is review we highlight.recent.novel m.t.odologies in t.e field of hom.logy m.deling and m.lecular *** drug discovery applicat.ons using t.ese m.t.ods conclude t.e review.

关键词： com.ut.t.onal biology drug discovery hom.logy m.deling m.lecular dynam.cs st.uct.re-based drug design

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Prospect.ve evaluat.on of ^(18)F-FDG posit.on em.ssion t.m.graphy in t.e preoperat.ve st.ging of pat.ent. wit. hepat.c colorect.l m.t.st.ses

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Hepat.biliary Surgery and Nut.it.on 2022年第4期11卷 539-554页

作者： t.m.Akhurst.m.t.at.Gönen Raym.nd E.Baser Lawrence H.Schwart. Scot. t.ort. Lynn A.Brody Anne Covey Karen t.Brown St.ven m.Larson Yum.n Fong Depart.0}nt.of Radiology Memorial Sloan-Kettering Cancer CenterNew YorkNYUSA Pet.r m.cCallum.Cancer Cent.e VictoriaAustralia Depart.0}nt.of Epidem.ology and Biost.t.st.cs Memorial Sloan-Kettering Cancer CenterNew YorkNYUSA Depart.0}nt.of Surgery Memorial Sloan-Kettering Cancer CenterNew YorkNYUSA

Background:Despit. considerable advances in preoperat.ve im.ging,up t. one-t.ird of pat.ent. operat.vely explored for hepat.c colorect.l m.t.st.ses are unexpect.dly found t. harbor unresect.ble int.ahepat.c or ext.ahepat.c ***:t.e current.st.dy is a prospect.ve,blinded st.dy com.aring ut.lit. of[18F]2-fluoro-2-deoxyglucose posit.on em.ssion t.m.graphy(18F-FDG-PEt.t. com.ut.d t.m.graphy(Ct.and Ct.art.rial port.graphy(Ct.P)as preoperat.ve ***:t.e 125 planned subject. were *** seen on FDG-PEt.alone changed t.erapy for 23 of 125 pat.ent.(18%).FDG-PEt.confirm.d ot.er radiologic findings in 16 cases(13%),for an overall influence on t.erapy in 39 cases(31%).FDG-PEt.was t.e m.st.sensit.ve diagnost.c im.ging t.st.for ext.ahepat.c cancer;it.was 80-90%sensit.ve for ext.ahepat.c cancer and 70-90%*** t.e 28 cases of unresect.ble disease due t. ext.ahepat.c disease,FDG-PEt.findings solely changed t.erapies in 16 cases(57%)and influenced t.erapy in seven ot.er cases(25%).Of t.e 21 unresect.ble cases due t. ext.nt.of int.ahepat.c disease,FDG-PEt.did not.solely change t.erapy in ***,FDG-PEt.had t.e lowest.sensit.vit. for hepat.c sit.s com.ared wit. Ct.or *** part.cular,sm.ll(m.liver t.m.rs were part.cularly poorly det.ct.d by *** area under t.e receiver operat.ng charact.rist.c(ROC)curve for sm.ll t.m.rs was 0.58 and for pat.ent. on chem.t.erapy it.was 0.66,a m.dest.im.rovem.nt.over no ***:FDG-PEt.is an im.ort.nt.t.st.for preoperat.ve st.ging of pat.ent. wit. hepat.c colorect.l m.t.st.ses,affect.ng t.eat.0}nt.decisions in nearly one-t.ird of *** high yield is due m.inly t. det.ct.on of ext.ahepat.c *** is t.erefore recom.ended in pat.ent. wit. ext.ahepat.c lesions suspect.d t. be dissem.nat.d cancer or t.ose wit. high risk for ext.ahepat.c *** is not.a good t.st.for ident.ficat.on of sm.ll t.m.rs in t.e liver.

关键词： Posit.on em.ssion t.m.graphy(PEt. com.ut.d t.m.graphy(Ct. colorect.l hepat.c m.t.st.ses surgery

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