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Frontiers of Structural and Civil Engineering 2022年第1期16卷 99-116页

作者： gizem kac.roglu Mehmet SALTAN Department of Civil Engineering Suleyman Demirel UniversityIsparta 32200Turkey

In this study,bituminous binder was modified with Cocamide Diethanolamide chemical,a non-ionic surfactant,and the physical and rheological properties of modified binders were *** addition,Cocamide Diethanolamide has been used for the first time to modify bituminous binder,and this situation makes the study *** binder was modified more than once with the chemical by changing modification parameters and using certain additive ratios(1%,3%,and 5%).The effects of different modification parameters and chemical additive on modified samples were investigated with conventional bitumen tests(softening point,penetration,ductility)and Superpave tests(rotational viscometer,rolling thin film oven test,pressure aging vessel,dynamic shear rheometer,bending beam rheometer).In addition,the structural characteristics of the reference binder and modified samples were examined by X-ray diffraction,Fourier Transform Infrared Spectroscopy,scanning electron microscopy,and energy dispersive X-ray *** examinations showed that Cocamide Diethanolamide softens bituminous binder and lowers processing *** addition,compared to reference binder,rutting resistances of modified bituminous binders decreased with the increase of additive ***,modification with Cocamide Diethanolamide increased the resistance to fatigue cracks and thermal cracks.

关键词： Cocamide Diethanolamide bitumen modification rheology Superpave tests

The geomechanical properties of soils treated with nanosilica particles

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第4期15卷 954-969页

作者： gizem Aksu Tugba Eskisar Asia Prefabrik Ltd.Co. KemalpasaIzmir35730Turkey Department of Civil Engineering Ege UniversityBornovaIzmir35100Turkey

This study examines the effect of nanosilica(NS)additive to improve the mechanical properties of clay,clayey sand,and *** engineering properties of the soils were investigated through Atterberg limits,compaction,unconfined compression,ultrasonic pulse velocity(UPV),freeze-thaw,and direct shear *** NS content varied from 0%to 0.7%and cement content was 5%and 10%by the dry weight of the *** curing period varied from 7 d to 150 *** consistency,compaction,and strength properties of the soils were affected by the presence of NS and *** optimum NS contents in clay specimens with 5%and 10%cement were 0.5%and 0.7%,*** was 0.7%in sand specimens with both cement ratios,as well as 0.3%and 0.7%in clayey sand specimens with 5%and 10%cement,*** terms of freeze-thaw resistance,clayey sand specimens containing 0.5%NS and 10%cement had the minimum strength *** relationships existed between the ultrasonic pulse velocity(UPV)and the unconfined compressive strength(UCS)of soil specimens having the same curing *** shear strength parameters of the soils also improved with the addition of *** electron microscope(SEM)images demonstrated that cement and NS contributed to the improvement of the soils by producing a denser and more uniform *** was concluded that the minor addition of NS could potentially improve the geomechanical properties of the soils.

关键词： Nanosilica(NS) Atterberg limits Compaction Unconfined compressive strength(UCS) Ultrasonic pulse velocity(UPV) Freeze-thaw

A Hybrid Multi-Hazard Susceptibility Assessment Model for a Basin in Elazig Province,Türkiye

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International Journal of Disaster Risk Science 2023年第2期14卷 326-341页

作者： gizem Karakas Sultan Kocaman Candan Gokceoglu Graduate School of Science and Engineering Hacettepe University06800BeytepeAnkaraTurkey Department of Geomatics Engineering Hacettepe University06800BeytepeAnkaraTurkey Department of Geological Engineering Hacettepe University06800BeytepeAnkaraTurkey

Preparation of accurate and up-to-date susceptibility maps at the regional scale is mandatory for disaster mitigation,site selection,and planning in areas prone to multiple natural *** this study,we proposed a novel multi-hazard susceptibility assessment approach that combines expert-based and supervised machine learning methods for landslide,flood,and earthquake hazard assessments for a basin in Elazig Province,Tü*** produce the landslide susceptibility map,an ensemble machine learning algorithm,random forest,was chosen because of its known performance in similar *** modified analytical hierarchical process method was used to produce the flood susceptibility map by using factor scores that were defined specifically for the area in the *** seismic hazard was assessed using ground motion parameters based on Arias intensity *** univariate maps were synthesized with a Mamdani fuzzy inference system using membership functions designated by *** results show that the random forest provided an overall accuracy of 92.3%for landslide susceptibility *** the study area,41.24%were found prone to multi-hazards(probability value>50%),but the southern parts of the study area are more *** proposed model is suitable for multi-hazard susceptibility assessment at a regional scale although expert intervention may be required for optimizing the algorithms.

关键词： Earthquakes Floods Fuzzy inference systems Landslides Multi-hazard susceptibility assessment Random forest Türkiye

A novel Fe/HNT visible light-driven heterogeneous photocatalyst:Development as a semiconductor and photocatalytic application

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Progress in Natural Science:Materials International 2022年第3期32卷 273-281页

作者： gizem Basaran Dindas Derya Y.Koseoglu-Imer Huseyin Cengiz Yatmaz Gebze Technical University Environmental Engineering Department Istanbul Technical University Environmental Engineering Department

Fe/HNT(Iron/Halloysite-nanotube) heterogeneous semiconductor catalysts operating effectively under visible light were developed by using FeCl3, FeSO4and Fe(OH)3sludge precipitated after electro-Fenton process and named as Fe/HNT-I, Fe/HNT-II and Fe/HNT-III, respectively. Chemical configuration and particle morphology of the catalysts were characterized with XRD, SEM-EDS and UV–vis DRS. Effect of the developed Fe/HNT photocatalysts was investigated for the degradation of Reactive Orange 16(RO16) textile dye under visible light. The photocatalytic decolorization of RO16 was 95.6%, 99.3% and 96.6%, respectively. It was found that the photocatalytic performance of Fe/HNT-III catalyst under visible light was effective compared to Fe/HNT-I and Fe/HNTII. The iron ratio in the catalyst’s structure(Fe:HNT ratio 0.25, 0.5 and 0.75(w/w)) and p H value(4, 7 and 9) in production phase were also changed to investigate the photocatalytic effect of Fe/HNT-III. An Fe:HNT ratio of 0.25 and a p H of 4 were determined as the optimum conditions for catalyst production. Optimum H2O2dosage value was also investigated for photocatalytic oxidation process and determined to be 10 m M. Finally, the optimum conditions were further used for the degradation of Terbinafine hydrochloride(Ter HCl) active drug and the treatment of wastewater from the textile and pharmaceutical industries.

关键词： Halloysite nanoclay Fe/HNT nanoparticle Catalyst Semiconductor Photocatalytic degradation Visible light

Host genetic factors affecting hepatitis B infection outcomes:Insights from genome-wide association studies

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World Journal of Gastroenterology 2018年第30期24卷 3347-3360页

作者： Izzet Mehmet Akcay Seyma Katrinli Kamil Ozdil gizem Dinler Doganay Levent Doganay Department of Molecular Biology and Genetics Istanbul Technical University Department of Gastroenterology and Hepatology Umraniye Teaching and Research Hospital

The clinical outcome of hepatitis B virus(HBV) infection depends on the success or failure of the immune responses to HBV,and varies widely among individuals,ranging from asymptomatic self-limited infection,inactive carrier state,chronic hepatitis,cirrhosis,hepatocellular carcinoma,to liver failure,depending on the success or failure of immune response to ***-wide association studies(GWAS) identified key genetic factors influencing the pathogenesis of HBV-related *** this review,we discuss GWAS for persistence of HBV infection,antibody response to hepatitis B vaccine,and HBV-related advanced liver *** persistence is associated with multiple genes with diverse roles in immune *** strongest associations are found within the classical human leukocyte antigen(HLA) genes,highlighting the central role of antigen presentation in the immune response to *** variants affect both epitope binding specificities and expression levels of HLA *** other susceptibility genes regulate the magnitude of adaptive immune responses,determining immunity vs *** persistence and nonresponse to vaccine share the same risk variants,implying overlapping genetic *** the other hand,the risk variants for HBV-related advanced liver diseases are largely different,suggesting different host-virus dynamics in acute vs chronic HBV *** findings of these GWAS are likely to pave the way for developing more effective preventive and therapeutic interventions by personalizing the management of HBV infection.

关键词： Genome-wide association studies Hepatitis B infection Hepatocellular carcinoma Cirrhosis Antigen presentation Immune response to hepatitis B virus

Patterns in the relationship between acute COVID-19/long COVID-19 and quality of life:A cross-sectional study of patients attending a tertiary care hospital in Turkey

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Asian Pacific Journal of Tropical Medicine 2022年第6期15卷 274-282页

作者： Hakan Tuzun Cansu Ozbaş Burkay Budak gizem Altunay F.N.Baran Aksakal Department of Public Health Faculty of MedicineGazi UniversityAnkaraTurkey

Objective:To determine the change in the quality of life(QoL)of patients who applied to a tertiary outpatient clinic according to their COVID-19 ***:This cross-sectional study comprised 1370 *** form-12(SF-12),which includes Physical Component Summary(PCS)and Mental Component Summary(MCS)domains,was used to evaluate the *** linear regression models created using PCS-12 and MCS-12 were dependent ***:A total of 19.2% of participants had acute COVID-19,and 8.4%had long *** most common sypmtoms were fatigue(72.6%),headache(42.5%),and joint pain(39.8%)in patients with long *** model including all participants showed that long COVID-19 reduced the QoL in multivariate analysis for both MCS and PCS,while acute COVID-19 had no significant effect on the QoL comparing with those without *** that included participants with COVID-19 showed that long COVID-19 negatively affected the QoL in the multivariate model for PCS-12 and *** that were significant in the multivariate model for those who had long COVID-19 were having a chronic disease and presence of ongoing *** were disadvantaged for PCS-12 and MCS-12 in the multivariate models including all participants,and models including participants who have had *** educational group were disadvantaged for PCS-12 in the multivariate model including all *** group were also disadvantaged for PCS-12 and MCS-12 in the multivariate models including participants who had ***:In studies,acute COVID-19 and long COVID-19 should be treated as separate *** effects of long COVID-19 should be considered when providing and planning health *** effect of gender,and education,on QoL shows that health inequalities continue to be effective during the pandemic period.

关键词： Long COVID-19 Acute COVID-19 Quality of life Pandemic Health ineaqualities

Effect of asymmetric rolling process on the microstructure,mechanical properties and texture of AZ31 magnesium alloys sheets produced by twin roll casting technique

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Journal of Magnesium and Alloys 2014年第1期2卷 92-98页

作者： Selda Ucuncuoglu Ahmet Ekerim gizem Oktay Secgin Ozgur Duygulu TVBİTAK Marmara Research Center Materials InstituteGebzeKocaeliTurkey Yildiz Technical University Faculty of Chemical and Metallurgical EngineeringDepartment of Metallurgy and Materials Engineering34210 EsenlerİstanbulTurkey

Symmetric rolling(SR)and asymmetric rolling(ASR)processes were carried out on 6 mm thick AZ31 magnesium alloy sheets that were produced by twin roll casting(TRC)*** rolling processes,sheets were heat treated in order to obtain a homogenized *** this study,for the ASR process the rolling speed ratio between upper roller and lower was selected as *** SR and ASR processes were utilized with 40%reduction per passes using 2 pass schedule for a total reduction ratio of *** and asymmetric rolled sheets were characterized using optical microscopy(OM),scanning electron microscopy(SEM)and transmission electron microscopy(TEM)*** measurements were performed by using X-ray diffraction(XRD)technique and mechanical properties were investigated by tensile tests and also hardness measurements.

关键词： Asymmetric rolling(ASR) AZ31 magnesium alloy Texture Twin roll casting

Adipose-derived stem cells in the treatment of hepatobiliary diseases and sepsis

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World Journal of Clinical Cases 2022年第14期10卷 4348-4356页

作者： Basri Satilmis gizem Selen Cicek Egemen Cicek Sami Akbulut Tevfik Tolga Sahin Sezai Yilmaz Hepatology Research Laboratory Liver Transplant InstituteInonu UniversityMalatya 44000BattalgaziTurkey Department of Biochemistry Faculty of PharmacyInonu UniversityMalatya 44000BattalgaziTurkey Department of Anesthesiology and Reanimation Malatya Training and Research HospitalMalatya 44000YesilyurtTurkey Liver Transplant Institute InonuUniversityMalatya 44000BattalgaziTurkey

Determination of the mesenchymal stem cells is one of the greatest and most exciting achievements that tissue engineering and regenerative medicine have ***-derived mesenchymal stem cells(AD-MSC)are easily isolated and cultured for a long time before losing their stem cell characteristics,which are self-renewal and ***-MSC are mesenchymal stem cells that have pluripotent lineage *** are easily accessible,and the fraction of stem cells in the adipose tissue lysates is highest among all other sources of mesenchymal stem *** is also HLA-DR negative and can be transplanted allogenically without the need for *** advantages have popularized its use in many fields including plastic reconstructive ***,in the field of hepatology and liver transplantation,the progress is ***-MSC have the potential to modulate inflammation,ameliorate ischemia-reperfusion injury,and support liver and biliary tract *** are very important for the treatment of various hepatobiliary ***,the anti-inflammatory potential of these cells has paramount importance in the treatment of *** need alternative therapeutic approaches to treat end-stage liver ***-MSC can provide a means of therapy to bridge to definitive therapeutic alternatives such as liver *** we propose to review theoretic applications of AD-MSC in the treatment of hepatobiliary diseases and sepsis.

关键词： Adipose-derived stem cells Hepatobiliary diseases Sepsis Mesenchymal stem cells Theoretic application

Artificial neural network analysis of the day of the week anomaly in cryptocurrencies

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Financial Innovation 2023年第1期9卷 2558-2581页

作者： Nuray Tosunoğlu Hilal Abacı gizem Ateş Neslihan SaygılıAkkaya Faculty of Economics and Administrative Sciences Ankara HacıBayram Veli UniversityAnkaraTurkey Faculty of Economics and Administrative Sciences ÇankırıKaratekin UniversityÇankırıTurkey Faculty of Economics and Administrative Sciences İnönüUniversityMalatyaTurkey Institute of Graduate Studies Ankara HacıBayram Veli UniversityAnkaraTurkey

Anomalies,which are incompatible with the efficient market hypothesis and mean a deviation from normality,have attracted the attention of both financial investors and researchers.A salient research topic is the existence of anomalies in cryptocurrencies,which have a different financial structure from that of traditional financial *** study expands the literature by focusing on artificial neural networks to compare different currencies of the cryptocurrency market,which is hard to *** aims to investigate the existence of the day-of-the-week anomaly in cryptocurrencies with feedforward artificial neural networks as an alternative to traditional *** artificial neural network is an effective approach that can model the nonlinear and complex behavior of *** October 6,2021,Bitcoin(BTC),Ethereum(ETH),and Cardano(ADA),which are the top three cryptocurrencies in terms of market value,were selected for this *** data for the analysis,consisting of the daily closing prices for BTC,ETH,and ADA,were obtained from the *** website from January 1,2018 to May 31,*** effectiveness of the established models was tested with mean squared error,root mean squared error,mean absolute error,and Theil’s U1,and R2 OOS was used for *** Diebold–Mariano test was used to statistically reveal the difference between the out-of-sample prediction accuracies of the *** the models created with feedforward artificial neural networks are examined,the existence of the day-of-the-week anomaly is established for BTC,but no day-of-the-week anomaly for ETH and ADA was found.

关键词： Cryptocurrency Bitcoin Ethereum Cardano Day-of-the-week anomaly Artificial neural network

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World Journal of Clinical Cases 2022年第19期10卷 6722-6727页

作者： Aysegul Gencer gizem Ozcibik Fatma Gulsum Karakas Ismail Sarbay Sebnem Batur Sermin Borekci Akif Turna Department of Pulmonary Diseases Istanbul University-CerrahpasaCerrahpasa Medical Faculty CampusIstanbul 34098Turkey Department of Thoracic Surgery Istanbul University-CerrahpasaCerrahpasa Medical FacultyIstanbul 34098Turkey Department of Pathology Istanbul University-CerrahpasaCerrahpasa Medical FacultyIstanbul 34098Turkey

BACKGROUND Pulmonary Langerhans cell histiocytosis(PLCH)is a rare cystic lung disease usually affecting young *** is predicted that PLCH is a lung tumor precursor associated with dysfunction of the myeloid dendritic cells in the *** SUMMARY A 70-year-old male patient presented with chronic cough and *** had symptoms for 5 years and described shortness of breath on exertion for the previous 3 *** had a 60 packs/year smoking *** tomography of the thorax revealed an 11-mm nodule in the right lung lower lobe superior segment and a 7-mm nodule in the right lung lower lobe poster basal *** two nodules were resected by means of right thoracoscopic *** evaluation revealed a squamous cell carcinoma and *** Coexistent squamous cell carcinoma and PLCH suggest possible association between PLCH and lung cancer.

关键词： Pulmonary Langerhans cell histiocytosis Lung cancer Squamous cell carcinoma BRAF Mitogen-activated protein kinase Case report