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Linear endoscopic ultrasonography vs magnetic resonance imaging in ampullary tumors

World Journal of Gastroenterology 2010年第44期16卷 5592-5597页

作者： Raffaele Manta Rita Conigliaro Danilo Castellani Alessandro Messerotti Helga Bertani giuseppe sabatino Elena Vetruccio Luisa Losi Vincenzo Villanacci Gabrio Bassotti Gastroenterology and Endoscopy Unit Nuovo Ospedale Civile Sant'Agostino EstenseViale Giardini 135541121 BaggiovaraModenaItaly Gastroenterology and Hepatology Section Department of Clinical and Experimental MedicineUniversity of Perugia Medical School06156 PerugiaItaly Department of Radiology S.Agostino Estense Civil Hospital41121 BaggiovaraModenaItaly Department of Pathology University of Modena41121 ModenaItaly Department of 2nd Pathology Spedali Civili25100 BresciaItaly

AIM:To assess linear endoscopic ultrasound (L-EUS) and magnetic resonance imaging (MRI) in biliary tract dilation and suspect small ampullary ***:L-EUS and MRI data were compared in 24 patients with small ampullary tumors;all with subsequent histological *** were collected prospectively and the accuracy of detection,histological characterization and N staging were assessed retrospectivelyusing the results of surgical or endoscopic treatment as a ***:A suspicion of ampullary tumor was present in 75% of MRI and all L-EUS examinations,with 80% agreement between EUS and histological findings at ***,L-EUS and histological TN staging at surgery showed moderate agreement (κ=0.54).CONCLUSION:L-EUS could be a useful adjunct as a diagnostic tool in the evaluation of patients with sus-pected ampullary tumors.

关键词： Ampullary tumors Endoscopic ultrasound Magnetic resonance imaging

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Is hyperhomocysteinemia relevant in patients with celiac disease?

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World Journal of Gastroenterology 2011年第24期17卷 2941-2944页

作者： Giovanni Casella Gabrio Bassotti Vincenzo Villanacci Camillo Di Bella Fabio Pagni Gian Luigi Corti giuseppe sabatino Mara Piatti Vittorio Baldini Division of Internal Medicine Desio General Hospital Gastroenterology and Hepatology Section Department of Clinical and Experimental MedicineOspedale Santa Maria della Misericordia 2nd Pathology Section Spedali Civili Pathology Unit Desio General Hospital Endoscopy Unit Division of SurgeryDesio General Hospital Laboratory Medicine Unit Desio General Hospital

AIM： TO investigate whether this might be related to the presence of hyperhomocysteinemia. METHODS： From January 1998 to December 2008, we evaluated the presence of hyperhomocysteinemia in a series of 165 adult celiac disease （CD） patients （138 females and 27 males, mean age 43 years）.RESULTS： Hyperhomocysteinemia was evident in 32 patients （19.3%）, although most of them had moderate levels （mean value 25 mcg/ml; range 15-30）. Only one patient had a history of myocardial infarction （heterozygosis for N5-N10-metil tetrahydrofolate reductase mutation）. CONCLUSION： The systematic assessment of hyperhomocysteinemia seems, at present, unjustified in CD patients.

关键词： Celiac disease Endoscopy Histology Hyperhomocysteinemia

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Functional Characterization of Bifidobacteria of Human Origin: A Case Study by the Students of Food Science and Technology of the University of Foggia (Southern Italy)

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Food and Nutrition Sciences 2014年第13期5卷 1153-1161页

作者： Emanuela Ciuffreda Angino Veronica Antonietta Cifelli Rossana Foti Rosaria Ilenia Forte Fabio Graziani Andrea giuseppe Longo Angela Longo Valeria Maglia Emilio Francesco Ricciardi Alessandra sabatino Annamaria Tomaiuolo Maria Rosaria Corbo Milena Sinigaglia Antonio Bevilacqua Department of the Science of Agriculture Food and Environment (SAFE) University of Foggia Foggia Italy

The aim of this paper was to study the potential technological and probiotic properties of bifidobacteria isolated from human feces. Bifidobacteria, naturally present in the dominant colonic microbiota, represent up to 25% of the cultivable faecal bacteria in adults and 80% in infants. Bifidobacteria have been shown to adhere and colonize in high numbers different types of cultured intestinal epithelial cells;moreover some authors reported that some strains are able to stabilize the intestinal microbiota during and after antibiotic therapy, modulate the immune system, protecting against chemically induced intestinal inflammation and reducing symptoms of colitis. Eight isolates of bifidobacteria were studied to assess their technological and probiotic traits;the technological characterization relied on the assessment of enzymatic activities (proteolytic and lipolytic activity), growth under various conditions (pH, temperature and addition of salt), acidifying ability and metabolism (arginine deamination, esculin, esculin hydrolysis and citrate metabolism). The study of the probiotic characteristics focused on the evaluation of the survival at low pH and with bile salts added, antibiotic resistance, and hydrophobic properties. As a result of this process, two promising strains were selected for further studies.

关键词： Bifidobacteria Technology Probiotic Traits Functional Characterization

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