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Geoscience Frontiers 2024年第1期15卷 304-324页

作者： Martina Busetti Riccardo Geletti Dario civile chiara Sauli giuseppe Brancatelli Edy Forlin Daniela Accettella Lorenza Barro Savonuzzi Laura De Santis Aldo Vesnaver Andrea cova National Institute of Oceanography and Applied Geophysics–OGS Borgo Grotta Gigante 42/c34010 SgonicoTriesteItaly

Seafloor and buried reliefs occur along continental margin of the Ross Sea(Antarctica).These features are several kilometres wide and tens of metres high,exhibiting cone or flat-top dome *** studies have proposed a volcanic or glacial origin for these formations,but these hypotheses do not account for all the available *** this study,we use morpho-bathymetric data,intermediate resolution multichannel seismic and high resolution chirp profiles,as well as magnetic lines to investigate these clusters of *** employing targeted processing techniques to enhance the geophysical characterization of the seafloor and buried reliefs,and to understand the underlying geological features,we propose that the reliefs are mud *** of these formations appear to be associated with a plumbing system,as indicated by acoustic anomalies linked to sediment containing *** formations are likely fed by clayey source rocks of Miocene ***,other reliefs might be the result of mud mobilisation caused by gravity instability and fluid overpressure.

关键词： Ross Sea Antarctica Mud volcanoes Gas plumbing system Gas hydrate Bottom Simulating Reflector

Fuzzy-entropy based robust optimization criteria for tuned mass dampers

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Earthquake Engineering and Engineering Vibration 2010年第2期9卷 285-294页

作者： giuseppe carlo Marano giuseppe Quaranta Sara Sgobba Department of Environmental Engineering and Sustainable Development Technical University of Bari Department of Structural Engineering and Geotechnics University of Rome "La Sapienza" Faculty of Engineering International University UNINETTUNO

Tuned mass dampers (TMD) are well known as one of the most widely adopted devices in vibration control passive strategies. In the past few decades,many methods have been developed to find the optimal parameters of a TMD installed on a structure and subjected to a random base excitation process,but most of them are usually based on an implicit assumption that all of the structural parameters are deterministic. However,in many real cases this simplification is unacceptable,so robust optimal design criteria becomes aviable alternative to better support engineers in the design process. In Robust Design Optimization (RDO) approaches,indeed the solution must be able to not only minimize the performance but also to limitits variation induced by uncertainty. Most of the currently available RDO methods are based on a probabilistic description of the model uncertainty,even if in many cases they are not able to explicitly include the influence of all the possible sources of uncertainties. Therefore,in this study,a fuzzy version of the robust TMD design optimization problem is proposed. The consistency of the fuzzy approach is studied with respect to the available non-probabilistic formulations reported in the literature and an application to an example of a robust design of a linear TMD subjected to base random vibrations in the presence of fuzzy uncertainties. The results show that the proposed fuzzy-based approach is able to give a set of optimal solutions both in terms of structural efficiency and sensitivity to mechanical and environmental uncertainties.

关键词： tuned mass damper random vibration robust design fuzzy variable expected value fuzzy entropy

Mechatronic Design of a Robot for Upper Limb Rehabilitation at Home

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Journal of Bionic Engineering 2021年第4期18卷 857-871页

作者： Elio Matteo curcio giuseppe c.rbone Department of Mechanical Energyand Management EngineeringUniversity of Calabria Via BucciCubo 46C87036 RendeItaly

This paper addresses the design of a novel bionic robotic device for upper limb rehabilitation tasks at *** main goal of the design process has been to obtain a rehabilitation device,which can be easily portable and can be managed remotely by a professional *** allows to treat people also in regions that are not easily reachable with a significant cost *** potential benefits can be envisaged,for instance,in the possibility to keep social distancing while allowing rehabilitation treatments even during a pandemic *** attention has been devoted to design the main mechatronic components by developing specific kinematics and dynamics *** design process includes the implementation of a specific control hardware and *** experimental tests are reported to show the effectiveness and feasibility of the proposed design solution.

关键词： bionic robot design simulations parallel robots upper limb rehabilitation

Intraocular inflammation after Ultrasound cyclo Plasty for the treatment of glaucoma

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International Journal of Ophthalmology(English edition) 2019年第2期12卷 338-341页

作者： Marco Pellegrini Stefano Sebastiani giuseppe Giannaccare Emilio c.campos Ophthalmology Unit S.Orsola-Malpighi University Hospital DIMES University of Bologna

This is a prospective interventional clinical study evaluating intraocular inflammation developed after Ultrasound cyclo Plasty(UcP) for the treatment of glaucoma. Eighteen eyes of 18 patients were treated with UcP second-generation probes(Eye OP1). After treatment, the mean intraocular pressure(IOP) significantly decreased from 26.8±7.2 to 18.8±6.1 mm Hg at day 1 and to 14.7±3.4 mm Hg at month 6(all Pcell photometry value steeply increased after surgery from 12.1±7.5 to 64.1±53.9 ph/ms(P=0.001) at day 1, and then progressively decreased to respectively 60.6±49.7 at day 7, 43.5±38.5 at day 14 and 28.2±18.3 at month 1(all Pctively 16.7±6.2 and 12.8±10.2, both P>0.05). A significant negative correlation was found between postoperative increase of aqueous flare values and anterior chamber depth(R=-0.568, P=0.014). This timeframe may be considered reasonable for repeating UcP treatment, when required.

关键词： Ultrasound cyclo Plasty glaucoma intraocular pressure ciliary body intraocular inflammation laser flare-cell photometry

cUBE, a cable-driven Device for Limb Rehabilitation

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Journal of Bionic Engineering 2019年第3期16卷 492-502页

作者： Daniele cafolla Matteo Russo giuseppe c.rbone IRccS Neuromed Via delFelettronica 86077 Pozzilli IS Italy University of Nottingham Advanced Manufacturing Building C47 Nottingham NG8 IBB UK DIMEG University of Calabria Via Bucci Cubo 46C 87036 Rende Italy cESTER Technical University of Cluj-Napoca MunciiAve. 103-105 400641 Cluj-Napoca Romania

In this paper, a novel cable-driven parallel robot, cUBE, is introduced for the assistance of patients in rehabilitation exercising of both upper and lower limbs. The system is characterized by a lightweight structure that is easy to set-up and operate, for both clinical and home usage for both pre-determined and customized exercises, with control over the position of the end-effector while locking its rotation around the horizontal axes. Its cable-driven design makes it inherently safe in human/robot interactions also due to the extremely low inertia. While a novel end-effector design makes the device wearable both on the upper and lower limbs without having to disassemble any part of the structure. The design is presented with its kinematic analysis. Then, the manufacturing through 3D?printing and commercial components of a first prototype is reported. Finally, the system is validated through motion tests along simple trajectories and two different spatial exercises.

关键词： cable-driven robots medical robots parallel robots rehabilitation devices

Plasmon hybridization engineering in self-organized anisotropic metasurfaces

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Nano Research 2018年第7期11卷 3943-3956页

作者： Maria c. Giordano Stefano Longhi Matteo Barelli Andrea Mazzanti Francesco Buatier de Mongeot giuseppe Della Valle Dipartimento di Fisica Universita di Genova Via Dodecaneso 33 Genova I-16146 Italy Dipartimento di Fisica and IFN-cNR Politecnico di Milano Piazza L. da Vinci 32 Milano 1-20133 Italy

The engineering of self-organized plasmonic metasurfaces is demonstrated using a maskless technique with defocused ion-beam sputtering and kinetically controlled deposition. The proposed reliable, cost-effective, and controllable approach enables large-area （order of square centimeter） sub-wavelength periodic patterning with close-packed gold nanostrips. A multi-level variant of the method leads to high-resolution manufacturing of vertically stacked nanostrip dimer arrays, without resorting to lithographic approaches. The design of these self-organized metasurfaces is optimized by employing plasmon hybridization methods. In particular, preliminary results on the so-called gap-plasmon configuration of the nanostrip dimers, implementing magnetic dipole resonance in the near-infrared range, are reported. This resonance offers a superior sensitivity and field enhancement, compared with the more conventional electric dipole resonance. The translational invariance of the nanostrip configuration leads to a high filling factor of the hot spots. These advanced features make the large-area metasurface based on gap-plasmon nanostrip dimers very attractive for surface-enhanced linear and nonlinear spectroscopy （e.g., surface-enhanced Raman scattering） and plasmon-enhanced photon harvesting in solar and photovoltaic cells.

关键词： metasurfaces self-organization gold nanostructures plasmon hybridization gap plasmon resonances

Exploring the contribution of the mitochondrial disulfide relay system to Parkinson’s disease:the PINK1/cHcHD4 interplay

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Neural Regeneration Research 2021年第11期16卷 2222-2224页

作者： giuseppe Arena Nazanine Modjtahedi Rejko Kruger Translational Neuroscience group Luxembourg Centre for Systems Biomedicine(LCSB)University of LuxembourgEsch-sur-AlzetteLuxembourg UniversitéParis-Saclay Gustave Roussy InstituteCNRSMetabolic and systemic aspects of oncogenesis for new therapeutic approachesVillejuifFrance Parkinson Research clinic Centre Hospitalier du Luxembourg(CHL)Esch-sur-AlzetteLuxembourg Transversal Translational Medicine Luxembourg Institute of Health(LIH)Esch-sur-AlzetteLuxembourg

Parkinson’s disease(PD)is a common movement disorder of the elderly caused by the degeneration of dopaminergic neurons in the substantia nigra pars compacta of the *** environmental and genetic factors pointed out mitochondrial dysfunction as a major cause of neurodegeneration in *** studies using mitochondrial toxins revealed their ability to trigger dopaminergic cell death and irreversible parkinsonism in different animal models(Poewe et al.,2017).Typical features of mitochondrial dysfunction have been also observed in the human brain of idiopathic PD cases,showing alterations of respiratory chain complex I and IV activity,accumulation of mtDNA deletions and increased oxidative stress(Bender et al.,2006).Moreover,a number of genes found mutated in familial PD forms encode for proteins involved in the maintenance of mitochondrial homeostasis and quality *** these,the PINK1 gene encodes a mitochondrial serine/threonine kinase implicated in key neuroprotective functions,including mitophagy,regulation of mitochondrial transport,control of the mitochondria/endoplasmic reticulum crosstalk and calcium homeostasis(Brunelli et al.,2020).

关键词： PINK1 homeostasis protective

Assessing tree crown fire damage integrating linear spectral mixture analysis and supervised machine learning on Sentinel-2 imagery

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International Journal of Digital Earth 2023年第1期16卷 3162-3198页

作者： Giandomenico De Luca giuseppe Modica Joao M.N.Silva Salvatore Praticò JoséM.c.Pereira Dipartimento di Agrari1 Universitàdegli Studi Mediterranea di Reggio Calabri1Reggio Calabri1Italy Dipartimento di Scienze veterinarie Universitàdegli Studi di Messin1Messin1Italy Forest Research centre School of AgricultureUniversity of LisbonLisbonPortugal

crown fire damage is a mixture of three principal fire-related components:charred material,scorched foliage,and unaltered green *** study estimated the abundance of these physical alterations in two immediate post-fire Mediterranean forest contexts(Portugal and Italy)by applying linear spectral mixture analysis(LSMA)on Sentinel-2 *** tree crowns fire damage was subsequently mapped,integrating fractional abundance information in a random forest(RF)algorithm,comparing the accuracy resulting from the adoption of generic or image spectral libraries as the primary investigative *** image-derived endmembers resulted in more effectiveness in terms of fire-related components abundance quantification(LMSAderived RMSEcores always were≥90%whether generic endmembers or image endmembers derived information was *** environmental heterogeneity of the two study areas affected the fire severity gradients,with a prevalence of the charred(PT)(45–46%)and green class(IT)(44–53%).Post-fire temporal monitoring was initialized by applying the proposed strategies,and the preliminary results showed a positive recovery trend in forest vegetation from the first year following the fire event,with a reduced charcoal predominance and an increasing proportion of green components.

关键词： Post-fire assessment fire severity post-fire vegetation recovery random forest(RF) scikit-learn fraction image extraction spectral unmixing endmembers crown fire damage mapping fully constrained least squares pixel purity index

An operator methodology for the global dynamic analysis of stochastic nonlinear systems

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Theoretical & Applied Mechanics Letters 2023年第3期13卷 164-169页

作者： Kaio c.B.Benedetti Paulo B.Goncalves Stefano Lenci giuseppe Rega Department of civil and Environmental Engineering Pontifical Catholic University of Rio de JaneiroRio de JaneiroBrazil Department of civil and Building Engineering and Architecture Polytechnic University of MarcheAnconaItaly Department of Structural and Geotechnical Engineering Sapienza University of RomeRomeItaly

In a global dynamic analysis,the coexisting attractors and their basins are the main tools to understand the system behavior and ***,both basins and attractors can be drastically influenced by *** aim of this work is to illustrate a methodology for the global dynamic analysis of nondeterministic dynamical systems with competing ***,analytical and numerical tools for calculation of nondeterministic global structures,namely attractors and basins,are ***,based on the definition of the Perron-Frobenius,Koopman and Foias linear operators,a global dynamic description through phase-space operators is presented for both deterministic and nondeterministic *** this context,the stochastic basins of attraction and attractors’distributions replace the usual basin and attractor ***,numerical implementation of these concepts is accomplished via an adaptative phase-space discretization strategy based on the classical Ulam *** results of the methodology are presented for a canonical dynamical system.

关键词： Stochastic dynamics Global nonlinear dynamics coexisting attractors Operator methodology Adaptative discretization Noise

Role of exercise in the brain:focus on oligodendrocytes and remyelination

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Neural Regeneration Research 2023年第12期18卷 2645-2646页

作者： Grazia Maugeri Velia D'Agata giuseppe Musumeci Section of Anatomy Histology and Movement SciencesDepartment of Biomedical and Biotechnological SciencesUniversity of CataniaCataniaItaly Research center on Motor Activities(cRAM) University of CataniaCataniaItaly Department of Biology Sbarro Institute for Cancer Research and Molecular MedicineCollege of Science and TechnologyTemple UniversityPhiladelphiaPAUSA

The phrase“Mens sana in corpore sano”taken from Juvenal's Satires(127 a.c.)represents one of the best-known and most used sentences of all time,whose meaning in the modern age refers to the importance of physical activity for mental health and *** literature demonstrated the positive role of exercise in counteracting several diseases,such as diabetes,cardiovascular diseases,neurodegenerative diseases,cancers and age-related disorders including muscle atrophy,the reduction of aerobic capacity,bone and cartilage loss.

关键词： meaning such exercise