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AI Sentience and Socioculture

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Journal of Social Computing 2023年第3期4卷 205-220页

作者： AJ Alvero Courtney peña the Department of Sociology University of FloridaGainesvilleFL 32601USA the Stanford School of Medicine Stanford UniversityStanfordCA 94305USA

Artificial intelligence(AI)sentience has become an important topic of discourse and inquiry in light of the remarkable progress and capabilities of large language models(LLMs).While others have considered this issue from more philosophical and metaphysical perspectives,we present an alternative set of considerations grounded in sociocultural theory and ***,we focus on sociocultural perspectives on interpersonal relationships,sociolinguistics,and culture to consider whether LLMs are *** examples grounded in quotidian aspects of what it means to be sentient along with examples of AI in science fiction,we describe why LLMs are not sentient and are unlikely to ever be *** present this as a framework to reimagine future AI not as impending forms of sentience but rather a potentially useful tool depending on how it is used and built.

关键词： sentience sociology sociolinguistics culture interpersonal relationships quotidian

level excursion analysis of probabilistic quasibrittle fracture

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Science China(Technological Sciences) 2020年第7期63卷 1141-1153页

作者： le Jia-Liang Department of Civil Environmentaland Geo-EngineeringUniversity of MinnesotaMinneapolis 55455USA

It has widely been acknowledged that no structures can be designed to be risk free, and therefore reliability analysis plays an essential role in the design of engineering structures. The recent focus has been placed on structures made of brittle heterogenous(a.k.a. quasibrittle) materials, such as ceramics, composites, concrete, rock, cold asphalt mixture, and many more at the microscale. This paper presents a level excursion model for the analysis of probabilistic failure of quasibrittle structures, in which the failure statistics is calculated as a first passage probability. The model captures both the spatial randomness of local material resistance and the random stress field induced by microstructures(e.g. randomly distributed flaws). The model represents a generalization of the classical weakest-link model at the continuum limit and it recovers the classical Weibull distribution as an asymptotic distribution function. The paper discusses two applications of the model. The model is first applied to the strength distribution of polycrystalline silicon(poly-Si) MEMS specimens. It is shown that the model agrees well with the experimentally measured strength distributions of poly-Si MEMS specimens of different sizes. The model predicts a complete size effect curve of the mean structural strength transitioning from a vanishing size effect at the small-size limit to the classical Weibull size effect at the large-size limit. The second application is concerned with the left tail of strength distribution of quasibrittle *** taking into account both random stress and strength fields, the model is used to investigate the origin of the power-law tail distribution of structural strength.

关键词： quasibrittle materials strength distribution first passage analysis Weibull statistics size effect

One ring is sufficient to inhibit α-synuclein aggregation

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Neural Regeneration Research 2022年第3期17卷 508-511页

作者： Samuel peña-Díaz Salvador Ventura Institut de Biotecnologia i Biomedicina Universitat Autònoma de BarcelonaBellaterraSpain Departament de Bioquímica i Biologia Molecular Universitat Autònoma de BarcelonaBellaterraSpain InstitucióCatalana de Recerca i Estudis Avançats(ICREA) BarcelonaSpain

Parkinson's disease,the second most prevalent neurodegenerative disorder worldwide,is characterized by a progressive loss of dopaminergic neurons in substantia nigra pars compacta,causing motor *** disorder's main hallmark is the formation of intraneuronal protein inclusions,named lewy bodies and *** major component of these arrangements is α-synuclein,an intrinsically disordered and soluble protein that,in pathological conditions,can form toxic and cell-to-cell transmissible amyloid *** α-synuclein aggregation has attracted significant effort in the search for a disease-modifying therapy for Parkinson's *** molecules like Synu Clean-D,epigallocatechin gallate,trodusquemine,or anle138 b exemplify this therapeutic ***,we describe a subset of compounds containing a single aromatic ring,like dopamine,ZPDm,gallic acid,or entacapone,which act as molecular chaperones against α-synuclein *** simplicity of their structures contrasts with the complexity of the aggregation process,yet the block efficiently α-synuclein assembly into amyloid fibrils,in many cases,redirecting the reaction towards the formation of non-toxic off-pathway ***,some of these compounds can disentangle mature α-synuclein amyloid *** simple structures allow structure-activity relationship analysis to elucidate the role of different functional groups in the inhibition of α-synuclein aggregation and fibril dismantling,making them informative lead scaffolds for the rational development of efficient drugs.

关键词： amyloid aromatic rings dopamine inhibition neurodegeneration oligomers Parkinson's disease protein aggregation α-synuclein

Finite Morse Index Solutions of a Nonlinear Schr?dinger Equation

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Acta Mathematica Sinica,English Series 2023年第3期39卷 513-522页

作者： Phuong le Faculty of Economic Mathematics University of Economics and LawHo Chi Minh CityVietnam Vietnam National University Ho Chi Minh CityVietnam

We prove Liouville type theorems for stable and finite Morse index H_(loc)^(1)∩L_(loc)^(∞)solutions of the nonlinear Schrodinger equation -Δu+λ|x|^(a)u=|x|b|^(u)|^(p-1)u in R^(N),where N≥2,λ>0,a,b>-2 and p>1,Our analysis reveals that all stable solutions of the equation must be zero for all p>1,Furthermore,finite Morse index solutions must be zero if N≥3 an p≥(N+2+2b)/(N-2).The main tools we use are integral estimates,a Pohozaev type identity and a monotonicity formula.

关键词： Schrodinger equation Liouville type theorems stable solutions finite Morse index solutions monotonicity formula

CLASSIFICATION OF SOLUTIONS TO HIGHER FRACTIONAL ORDER SYSTEMS

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Acta Mathematica Scientia 2021年第4期41卷 1302-1320页

作者： Phuong le Faculty of Economic Mathematics University of Economics and LawHo Chi Minh CityVietnam VietnamNational UniversityHo Chi Minh CityVietnam

let 00 for all s,t≥*** main technique we use is the method of moving spheres in integral *** our assumptions are more general than those in the previous literature,some new ideas are introduced to overcome this diffi... 详细信息

let 0lent integral *** classify all such solutions when f(s,t)is nondecreasing in s and increasing in t,g(s,t)is increasing in s and nondecreasing in i,and f(μ^(n-α)s,μ^(n-β)t)/μ^(n-α),g(μ^(n-α)s,μ^(n-β)t)/μ^(n-β)are nonincreasing in μ>0 for all s,t≥*** main technique we use is the method of moving spheres in integral *** our assumptions are more general than those in the previous literature,some new ideas are introduced to overcome this difficulty.

关键词： Higher fractional order system integral system general nonlinearity method of moving spheres classification of solutions

RANDOM ATMOSPHERIC PRESSURE AT THE FREE SURFACE AND MICROSEISMS IN DEEP OCEAN

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Journal of Hydrodynamics 2008年第6期20卷 741-748页

作者： le Jia-chun Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China

A general stochastic model of the atmospheric pressure at the ocean surface was proposed, in which the pressure variation was represented by a spectral decomposition through a random process of orthogonal increments. From the basic equations of ideal and incompressible fluid a set of perturbation equations up to second order had been derived and solved. The pressure variation in the flow field had been calculated using the explicit solutions obtained, and which demonstrated a clear relation between the atmospheric pressure and the one at the bottom of deep ocean. It can be seen that there is a part of the pressure variation which is not attenuating with the depth. The result had been compared with those of Longuet-Higgins and Kadota et al. and all previous results are contained in the solution given in this artice. The restriction on the previous works with regard to the probability law has been removed, and all conclusions are deduced without specific assumptions. The flexibility of the proposed model allows for further generalization and extension in the physical aspects and statistical treatment.

关键词： random waves water waves nonlinear interaction orthogonal increments spectral decomposition microseism

Analyses on the Ionization Instability of Non-Equilibrium Seeded Plasma in an MHD Generator

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Plasma Science and Technology 2016年第6期18卷 674-679页

作者： le Chi KIEN Ho Chi Minh City University of Technology and Education 01 Vo Van Ngan Thu DucHo Chi Minh City Vietnam

Recently,closed cycle magnetohydrodynamic power generation system research has been focused on improving the isentropic efficiency and the enthalpy extraction *** reducing the cross-section area ratio of the disk magnetohydrodynamic generator,it is believed that a high isentropic efficiency can be achieved with the same enthalpy *** this study,the result relating to a plasma state which takes into account the ionization instability of non-equilibrium seeded plasma is added to the theoretical prediction of the relationship between enthalpy extraction and isentropic *** a result,the electron temperature which reaches the seed complete ionization state without the growth of ionization instability can be realized at a relatively high seed fraction ***,the upper limit of the power generation performance is suggested to remain lower than the value expected in the low seed fraction *** is also suggested that a higher power generation performance may be obtained by implementing the electron temperature range which reaches the seed complete ionization state at a low seed fraction.

关键词： isentropic efficiency enthalpy extraction ionization instability seed fraction

Boundless love:a German Professor Uli Schwarz in China

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Protein & Cell 2024年第8期15卷 553-558页

作者： le Kang State Key Laboratory of Integrated Management of pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijing 100101China

More than 20 years ago,an old German man embarked on a quest to explore the suburbs of Shanghai and the villages of jiangsu Province in search of antique Chinese *** was not a mere antique collector or aficionado of ancient furmiture,but a German scientist motivated by his profound love of Chinese *** name was Uli Schwarz(Fig.1),a distinguished German scientist who had dedicated the majority of his life to promoting cross-cultural scientific exchanges,an effort that left an indelible mark on the landscape of research collaborations between China and Germany.

关键词： Schwarz German landscape

Sensitivity of wastewater surveillance: What is the minimum COVID-19 cases required in population for SARS-CoV-2 RNA to be detected in wastewater?

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Journal of Environmental Sciences 2023年第3期125卷 851-853页

作者： Connie le Li Ka Shing Institute of Virology Department of Radiation Oncologyand Cross Cancer InstituteUniversity of AlbertaEdmontonAlberta T6G 2G3Canada

Wastewater surveillance, also referred to as wastewaterbased surveillance (WBS) and wastewater-based epidemiology(WBE), has become a powerful tool for the monitoring, control, and prevention of infectious diseases, including COVID-19. Wastewater surveillance is a complementary and unbiased approach to evaluate disease burden at a population level(Hrudey et al., 2022;Kitajima et al., 2020;Kumblathan et al.,2021;Polo et al., 2020).

关键词： wastewater Wastewater prevention