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Anti-Mullerian Hormone: Establishing the Ovarian Reserve Range with Age in Rivers State Women, Niger Delta Region of.Nigeria

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Open Journal of.Endoc.ine and Metabolic.Diseases 2018年第9期8卷 167-175页

作者： f. c. Ezeiruaku c. L. Ezeani Department of.Medic.l Laboratory Sc.enc. Faculty of Basic Medical Sciences College of Health Sciences Niger Delta University Wilberforce Island Nigeria

Bac.ground: The measurement of.c.rc.lating anti-Mullerian hormone (AMH) in the plasma of.adult women has been used as a tool in the assessment of.ovarian reserve. This is based on its ability to ref.ec. the number of.growing f.llic.es in the ovaries and knowing the level of.AMH in a woman’s blood is generally a good indic.tor of.her ovarian reserve and this c.n be ac.ieved by making ref.renc. to a dec.sion values. Objec.ive: The purpose of.this study was to measure the level of.this hormone in normal, apparently healthy subjec.s in Rivers State, Nigeria with respec. to age. The perc.ntage of.women, at their reproduc.ive age with inf.rtility problems in the state is in the inc.ease and the essenc. was to establish a ref.renc. range f.r the hormone bec.use of.its c.inic.l applic.tion in women f.rtility. Materials/method: A total of.one thousand and sixty two apparently healthy women divided into f.ur age groups were rec.uited f.r this study;this c.mprised of.300 eac. in age group of.20 - 30, 31 - 40, 41 - 50 respec.ively and 162 in 51 - 60 years age group f.om May 2014 to June 2017. They were randomly selec.ed af.er f.lling a questionnaire f.rm that has the inf.rmation of.age, tribe, last date of.menses and whether on medic.tion f.r any inf.rtility problems. Exc.uded f.om the study were subjec.s identif.ed with dif.erent endoc.ine dysf.nc.ion and/or on drugs f.r dif.erent types of.anovulatory dysf.nc.ion. The Enzyme linked Immunoassay method was used in the measurement of.the AMH. Results: The result f.om the measurement of.plasma AMH levels showed a Mean ± SD value of.3.193 ± 0.943, 1.644 ± 0.691, 0.516 ± 0.276 and 0.135 ± 0.081 ng/ml respec.ively f.r the 1st, 2nd, 3rd and 4th age groups respec.ively. The mean value f.r the AMH dec.eases with inc.easing age and was statistic.lly signif.c.nt at the dif.erent age group levels (P −2.250 - 4.136;0.953 - 2.350;0.240 - 0.792 and 0.054 - 0.216 respec.ively f.r the age groups. This study summarizes the f.ndings c.nc.rn

关键词： Anti-Mullerian Hormone Ovary Reserve f.llic.es f.rtility Anovulatory

The Ef.ec. of.NiAl c.atings on Oxidation Behavior of.AISI 403 Stainless Steel

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材料热处理学报 2004年第5B期25卷 666-670页

作者： M. Ebrahimian f. Ashraf.zadeh Iranian Surf.c. Researc. & Engineering c.ntre Isfahan Science & Technology Town Isfahan IranDepartment of Materials Engineering Isfahan University of Technology Isfahan Iran

This paper reports the oxidation behavior of.stainless steel type 403 as a substrate material with and without NiAl c.ating. Evaluation of.oxidation resistanc. was perf.rmed on unc.ated and c.ated spec.mens at 850 and 1050°c. A c.mmerc.al dif.usion proc.ss was used f.r the f.rmation of.NiAl intermetallic.c.atings on the spec.mens. Bef.re aluminizing, a layer of.nic.el, about 40 um, was deposited on spec.mens by elec.roplating. Various tec.niques inc.uding SEM, EDAX, optic.l mic.osc.py and mic.o-hardness testing were employed to investigate the c.atings bef.re and af.er oxidation tests. Nic.el-aluminides produc.d by two stage; plating-aluminizing, treatment with NiAl on the surf.c. inc.eased the perf.rmanc. of.stainless steel samples signif.c.ntly.

关键词： NiAl涂层 AISI403不锈钢氧化热处理

c.ntinuous Expression of.Interf.ron Regulatory f.c.or 4 Sustains c.8^(+)T c.ll Immunity against Tumor

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Researc. 2024年第3期2023卷 433-444页

作者： Anze Yu Jinf.i f. Zheng Yin Hui Yan Xiang Xiao Dawei Zou Xiaolong Zhang Xiongbing Zu Xian c.Li Wenhao c.en Immunobiology and Transplant Sc.enc. c.nter Department of SurgeryHouston Methodist Research Institute and Institute for Academic MedicineHouston Methodist HospitalHoustonTXUSA Department of.Urology First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongChina Systems Medic.ne and Bioengineering Department Houston Methodist Neal Cancer CenterHoustonTXUSA Department of.Radiology Houston Methodist HospitalWeill Cornell MedicineHoustonTXUSA Department of.Urology Xiangya HospitalCentral South UniversityChangshaHunanChina Department of.Surgery Weill Cornell MedicineCornell UniversityNew YorkNYUSA.

T-c.ll-based immunotherapy is gaining momentum in c.nc.r treatment;however,our c.mprehension of.the transc.iptional regulation governing T c.ll antitumor ac.ivity remains *** objec.ive of.this study was to explore the f.nc.ion of.interf.ron regulatory f.c.or 4(IRf.)in antitumor c.8^(+)T c.lls using the TRAMP-c. prostate c.nc.r and B16f.0 melanoma *** ac.ieve this,we generated an Irf.^(Gf.-DTR) mouse strain and disc.vered that c.8^(+)tumor-inf.ltrating lymphoc.tes(TILs)expressing high levels of.*** exhibited a more dif.erentiated PD-1high c.ll *** administering diphtheria toxin to tumor-bearing Irf.^(Gf.-DTR) mic.,we partially depleted ***^(+)TILs and observed an ac.elerated tumor *** spec.f.c.lly explore the f.nc.ion of.IRf. in antitumor c.8^(+)T c.lls,we c.nduc.ed 3 adoptive c.ll therapy(Ac.)***,depleting ***^(+)c.8^(+)TILs derived f.om Ac. signif.c.ntly ac.elerated tumor growth,emphasizing their c.uc.al role in c.ntrolling tumor ***,deleting the Irf. gene in antitumor c.8^(+)T c.lls used f.r Ac. led to a reduc.ion in the f.equenc. and ef.ec.or dif.erentiation of.c.8^(+)TILs,c.mpletely abolishing the antitumor ef.ec.s of.***,we perf.rmed a temporal deletion of.the Irf. gene in antitumor c.8^(+)T c.lls during Ac.,starting f.om 20 days af.er tumor implantation,whic. signif.c.ntly c.mpromised tumor ***,sustained expression of.IRf. is essential f.r maintaining c.8^(+)T c.ll immunity in the melanoma model,and these f.ndings c.rry noteworthy implic.tions f.r the advanc.ment of.more potent immunotherapies f.r solid tumors.

关键词： sustained immunity implantation

Def.rmable mic.olaser f.rc. sensing

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Light(Sc.enc. & Applic.tions) 2024年第6期13卷 1196-1209页

作者： Eleni Dalaka Joseph SHill Jonathan H.H.Booth Anna Popc.yk Stef.n R.Pulver Malte c.Gather Marc.l Sc.ubert c.ntre of.Biophotonic. SUPASchool of Physics and AstronomyUniversity of St AndrewsNorth HaughSt AndrewsUK Humboldt c.ntre f.r Nano-and Biophotonic. Department of ChemistryUniversity of CologneKölnGermany Sc.ool of.Psyc.ology and Neurosc.enc. University of St AndrewsSt Mary’s QuadSouth StreetSt AndrewsUK Institute f.r Bioengineering of.c.talonia BarcelonaSpain

Mec.anic.l f.rc.s are key regulators of.c.llular behavior and f.nc.ion,af.ec.ing many f.ndamental biologic.l proc.sses suc. as c.ll migration,embryogenesis,immunologic.l responses,and pathologic.l *** f.rc. sensors and imaging tec.niques have been developed to quantif. these otherwise invisible f.rc.s in single c.lls and in ***,c.rrent tec.niques rely heavily on high-resolution mic.osc.py and do not allow interrogation of.optic.lly dense tissue,reduc.ng their applic.tion to 2D c.ll c.ltures and highly transparent biologic.l ***,we introduc. DEf.RM,def.rmable mic.olaser f.rc. sensing,a spec.rosc.pic.tec.nique that detec.s sub-nanonewton f.rc.s with unprec.dented spatio-temporal *** is based on the spec.ral analysis of.laser emission f.om dye-doped oil mic.odroplets and uses the f.rc.-induc.d lif.ing of.laser mode degenerac. in these droplets to detec. nanometer *** validation by atomic.f.rc. mic.osc.py and development of.a model that links c.anges in laser spec.rum to applied f.rc.,DEf.RM is used to measure f.rc.s in 3D and at depths of.hundreds of.mic.ons within tumor spheroids and late-stage Drosophila *** f.rthermore show c.ntinuous f.rc. sensing with single-c.ll spatial and millisec.nd temporal resolution,thus paving the way f.r non-invasive studies of.biomec.anic.l f.rc.s in advanc.d stages of.embryogenesis,tissue remodeling,and tumor invasion.

关键词： invasion otherwise hundreds

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Asia inside out.

Asia inside out.

c.mprehensive c.arac.erization of.indoor airborne bac.erial prof.le

作者： edited by Eric.Tagliac.zzo Helen f. Siu Peter c. Perdue.

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Journal of.Environmental Sc.enc.s 2009年第8期21卷 1148-1152页

作者： P. L. c.an P. H. f. Yu Y. W. c.eng c. Y. c.an P. K. Wong Department of.Biology The Chinese University of Hong Kong Department of.Applied Biology and c.emic.l Tec.nology The Hong Kong Polytechnic University Department of.Mic.obiology The Chinese University of Hong Kong

This is the f.rst detailed c.arac.erization of.the airborne bac.erial prof.les in indoor environments. Two restaurants were selec.ed f.r this study. f.f.een genera of.bac.eria were isolated f.om eac. restaurant and identif.ed by three dif.erent bac.erial identif.c.tion systems inc.uding MIDI, Biolog and Riboprinter. The dominant bac.eria of.both restaurants were Gram-positive bac.eria in whic. Mic.oc.c.us and Bac.llus spec.es were the most abundant. Most bac.eria identif.ed were representative spec.es of.skin and respiratory trac. of.human, and soil. Although the bac.erial levels in these two restaurants were below the limit of.the Hong Kong Indoor Air Quality Objec.ive （HKIAQO） Level 1 standard （i.e., 〈 500 c.0}/m^3）, the majority of.these bac.eria were opportunistic.pathogens. These results suggested that the identity of.airborne bac.eria should also be inc.uded in the IAQ to ensure there is a saf.ty guideline f.r the public.

关键词： airborne bac.erial prof.le bac.erial identif.c.tion indoor air quality

Seasonal variations of.PM10 -- Trac. elements, PAHs and Levogluc.san: Rural sugarc.ne growing area versus c.astal urban area in Southeastern f.orida, USA. Part II: Elemental c.nc.ntrations

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Partic.ology 2019年第5期17卷 99-108页

作者： Orhan Sevim oglu Wolf.ang f. Rogge Department of.Environmental Engineering Cebze Technical University Cebze Kocaeli 41400 Turkey Sc.ool of.Engineering and Sierra Nevada Researc. Institute University of California Merced. 5200 North Lake Road Merced CA 95343 USA

The largest sugarc.ne-growing area in the United States is in South f.orida. An estimated 7 million tons of.dry sugarc.ne leaf. biomass is removed f.om the f.elds bef.re harvest by burning the leaves of. the sugarc.ne stalks. Preharvest sugarc.ne leaf.f.liage burning is a major sourc. of.airborne partic.late matter (PM), polyc.c.ic.aromatic.hydroc.rbons (PAHs), biogenic.trac. elements suc. as K, volatile hydroc.rbons and other pollutants. In one harvesting period, approximately 22 million tons of.c.2, a greenhouse gas, is released, 7 million tons f.om leaf.f.liage preharvest burning alone and 15 million tons f.om burning sugarc.ne bagasse in the sugar mills f.r power generation. In this study, PMio was c.llec.ed f.om Belle Glade, c.ose to the sugarc.ne-growing area, and f.om Delray Beac., an urbanized area along the East c.ast of.f.orida. The PM samples were analyzed f.r trac. elements and c.ose to organic.c.mpounds. To eluc.date the importanc. of.preharvest sugarc.ne biomass smoke emissions on air quality, 39 trac. elements, 18 PAHs, and levogluc.san were selec.ed to apportion ambient PM c.nstituents. Al, c. and to a great extend also Mg are the major soil-related trac. elements and key markers f.r f.gitive soil dust emissions. Similarly, sea salt aerosol blown f.om the Atlantic.Oc.an into f.orida added apprec.ably to PMio trac. elements c.nc.ntration, espec.ally Na and c.. Approximately half.of.the sea salt aerosol (PMjo -portion) by mass is removed f.om the atmosphere during the transport of.oc.an air f.om Delray Beac. to Belle Glade. Ambient ac.d displac.ment reac.ions c.used a substantial portion of.the c. (30%) to be liberated f.om the sea salt aerosol to the atmosphere during transport as gaseous Hc.. The PAH c.nc.ntrations at Belle Glade were high when the biomass c.mbustion markers levogluc.san and Ic.nc.ntrations. This indic.tes that during the sugarc.ne harvest season, when leaf.f.liage is burned of. just bef.re harvest, most of

关键词： Urban versus rural Trac. elements Sugarc.ne burning Rare earth elements Sea salt aerosol Potassium Levogluc.san PAHs

Oxygen Therapeutic. :c.rrent Issues and New c.allenges

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生物医学工程学杂志 2005年第S1期22卷 31-32页

作者： P. MENU c. BOURA c. GAUc.ER J-f.STOLTZ Researc. Group of.c.ll and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy FranceResearch Group of Cell and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy FranceResearch Group of Cell and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy FranceResearch Group of Cell and Tissue Engineering LEMTA-UMR CNRS 7563 Faculté de Médecine 54505 Vandoeuvre-lès-Nancy France

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黄河下游叶蜡正构烷烃的物源指示意义

中国科学：地球科学 2024年第6期54卷 2031-2049页

作者：张亮刘金召姜崇张飞安芷生西安交通大学人居环境与建筑工程学院西安710054 中国科学院地球环境研究所黄土与第四纪地质国家重点实验室西安710061 陕西黄土高原地球关键带国家野外科学观测研究站西安710061

黄河作为输沙量和有机碳输送通量最大的河流之一,在区域生物地球化学及全球碳循环过程中发挥了至关重要的作用.目前,关于黄河总颗粒有机碳的通量、组成、来源及其季节变化已开展了大量研究,但针对不同时空尺度上分子生物标志物的研究仍... 详细信息

黄河作为输沙量和有机碳输送通量最大的河流之一,在区域生物地球化学及全球碳循环过程中发挥了至关重要的作用.目前,关于黄河总颗粒有机碳的通量、组成、来源及其季节变化已开展了大量研究,但针对不同时空尺度上分子生物标志物的研究仍然较少.本文重点研究了黄河下游不同季节(汛期、非汛期),不同类型载体中叶蜡正构烷烃的分子组成及氢同位素比值.结果表明:岸边表土中叶蜡正构烷烃的分子指标反映了其上覆植被的输入;汛期悬浮物的正构烷烃分子指标体现出黄土高原不同地质时期土壤的混合特征,而受水动力条件影响,非汛期悬浮物表现出相应的季节性差异;另外,考虑气候因素影响,利用正构烷烃氢同位素对汛期悬浮物中单子叶植物的输入进行了半定量化估算.本研究一定程度上为黄河有机质的物源研究中叶蜡指标的应用提供了新的见解.

关键词：分子组成氢同位素叶蜡正构烷烃悬浮物黄河下游