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enhancing perianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.

关键词： Perianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach

NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

Super d-antimagic Labelings of Disconnected Plane Graphs

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Acta Mathematica Sinica,english Series 2010年第12期26卷 2283-2294页

作者： Martin BAA Mirka MILLeR Oudone PHANALASY Andrea SeMANIOV-feOVKOV Department of Applied Mathematics Technical University School of electrical engineering and Computer Science The University of Newcastle Department of Mathematics University of West Bohemia Department of Computer Science King's College London Department of Mathematics National University of Laos

This paper deals with the problem of labeling the vertices, edges and faces of a plane graph in such a way that the label of a face and the labels of the vertices and edges surrounding that face add up to a weight of that face, and the weights of all s-sided faces constitute an arithmetic progression of difference d, for each s that appears in the graph. The paper examines the existence of such labelings for disjoint union of plane graphs.

关键词： Plane graph d-antimagic labeling super d-antimagic labeling disjoint union of graphs

Responsible research and innovation training programmes:implementation and evaluation of the HeIRRI project

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Forensic Sciences Research 2021年第3期6卷 320-330页

作者： Ružica Tokalić Ivan Buljan Niels Mejlgaard Mar Carrió Alexander Lang Gema Revuelta Ana Marušić HeIRRI Consortium Department of research in Biomedicine and health University of split school of Medicinesplitcroatia Danish centre for studies in research and research Policy Department of Political scienceaarhus UniversityaarhusDenmark health sciences education research Group Department of experimental and health sciencesPompeu Fabra UniversityBarcelonaspain Techno-science&societal Transformation research Group institut für höhere studien-institute for advanced studies(i)Viennaaustria estudies centre on science communication and societyDepartment of experimental and health sciencesPompeu Fabra UniversityBarcelonaspain

Responsible research and innovation,or RRI,is a concept that aims to bring together society and science for a better *** are six key elements of RRI:public engagement,gender equality,science education,open access,ethics and *** education Institutions and Responsible Research and Innovation(HeIRRI)project aimed to bring the concept of RRI into the educational *** state-of-the-art review of good practices,HeIRRI team developed 10 training programmes on RRI for different higher education institution educational levels,including a summer school and a massive open online course(MOOC).We conducted pilot of the trainings and evaluated participants’*** with HeIRRI training programmes on responsible research and innovation was high,both for participants and for the trainers,and trainings raised awareness of ***’feedback was used to identify areas that need improvement and provided for recommendations for final versions of the HeIRRI training *** order to equip researchers with skills to recognize and apply RRI values,RRI should be included in their *** training is suitable for a range of different disciplines,including forensic science,and is free to use and adjust for specific contexts(available from:https://***/heirri-training-programmes).

关键词： Research integrity research ethics responsible research and innovation responsibility societal inclusion higher education institutions RRI teaching

Free vibration and transient response of double curved beams connected by intermediate straight beams

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Applied Mathematics and Mechanics(english edition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-TALOOKOLAeI H.GHANDVAR e.JUMAeV S.KHATIR T.CUONG-Le School of Mechanical engineering Babol Noshirvani University of Technology Department of Mechanical engineering Faculty of Engineering New Uzbekistan University University of Business and Science Center for engineering Application and Technology Solutions Ho Chi Minh City Open University

This paper investigates the free vibration and transient response of interconnected structures including double curved beams and intermediate straight beams,which are all constructed from functionally graded porous(FGP) materials. The strain potential and kinetic energies of each beam along with the work done by the external force are calculated. Additionally, a higher-order beam element is introduced to derive stiffness and mass matrices, along with the force vector. The curved and straight beams are discretized, and their assembled stiffness, mass matrices, and force vectors, are *** conditions at the joints are used to derive the total matrices of the entire structure. Subsequently, the natural frequencies and transient response of the system are determined. The accuracy of the mathematical model and the self-developed computer program is validated through the comparison of the obtained results with those of the existing literature and commercial software ANSYS, demonstrating excellent ***, a comprehensive study is conducted to investigate the effects of various parameters on the free vibration and transient response of the considered structure.

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effect of salts on earthen materials deterioration after humidity cycling

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Journal of Central South University 2017年第4期24卷 796-806页

作者： SHeN Yun-xia CHeN Wen-wu KUANG Jing DU Wei-fe Key Laboratory of Mechanics on Disaster and environment in Western China (Lanzhou University) Lanzhou 730000 China School of Civil engineering and Mechanics Lanzhou University Lanzhou 73000 China Gansu Building Research Institute Xijin East Road 575 Lanzhou 730050 China China JK Institute of engineering Investigation and Design Xianning Road 52 Xi’an 710043 China

Salt weathering leads to destruction of many valuable cultural heritage monuments and porous building material. The present study aims at providing more laboratory evidence for evaluating the effects of salt precipitation on the deterioration process. In view of this, the remoulded soil specimens were mixed with three kinds of salts(i.e., NaCl, Na_2SO_4 and their mixture) with different salt concentrations, and the specimens were kept in environment cabinet for undergoing different wet-dry cycles. After each cycle, the ultrasound velocity measurements were employed to monitor the deterioration process. For the specimens that have suffered three wet-dry cycles, the mechanical properties(i.e. shear strength and compression strength) were determined to evaluate the degree of deterioration. Furthermore, considering the realistic conservation environment of earthen sites, mechanical stability of these specimens against sediment-carrying wind erosion was conducted in a wind tunnel. These experiments results indicate that the overall average velocities of the specimens after the third cycle are significantly lower than those subjected to only one cycle. Ultrasound velocity, mechanical strength and wind erosion rate decrease when salt content increases. However, the internal friction angle increases firstly, and then decreases with the increase in salt content added to the specimens. Na_2SO_4 contributes most of the surface deterioration, while NaCl plays little role in the deterioration. The damage potential of the salt mixture is less obvious and largely dependent on the crystallisation location.

关键词： earthen archaeological sites wet-dry cycles deterioration salt content salt crystallization

Male reproductive health research needs and research agenda:Asian and Chinese perspective

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Asian Journal of Andrology 1999年第1期1卷 13-20页

作者： Yi-fe WANG Department of Reproductive Health and Research, WHO, Geneva, Switzerland Department of Reproductive Health and Research WHO Geneva Switzerland

Research that addresses male reproductive health should assist in the development of reproductive healthprogrammes and policy; identify and test new leads in male contraceptive technology; establish effective maleinvolvement initiatives which are likely to have a positive impact on the reproductive health of men and women; guidethe allocation of health care resources to ensure cost-effectiveness of interventions; generate new knowledge, developdiagnostic technology in reproductive health and offer optimal treatment/care regimens. In considering the needs and demands of male reproductive health research in Asia and the Pacific, the followingsix research topics are recommended as the priority research areas: male contraceptive technology; male reproductivehealth behaviour and male adolescent reproductive health; male reproductive aging including male menopause and otherdiseases; male RTIs, STDs, HIV/AIDS; prevalence, management and prevention of male infertility; environment andsemen quality and other male reproductive problems. One of the major challenges now facing us is the elaboration of a comprehensive, yet realistic male reproductivehealth research agenda that reflect the needs and demands of Asian developing countries. To this end, to make use of aninterdisciplinary approach is of strategic importance. The most creative insights and productive leads are likely toemerge from a research team that is interdisciplinary especially in the field of reproductive health.

关键词： reproduction health andrology World Health Organization

An imaging spectrometer employing tunable hyperchromatic microlenses

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Light(Science & Applications) 2015年第1期4卷 33-41页

作者： Phuong-Ha Cu-Nguyen Adrian Grewe Patrik feßer Andreas Seifert Stefan Sinzinger Hans Zappe Gisela and erwin Sick Chair of Micro-optics Department of Microsystems EngineeringUniversity of FreiburgFreiburg 79110Germany Fachgebiet Technische Optik Institut fur Mikro-und NanotechnologienTechnische Universitat IlmenauIlmenau 98684Germany

We present the design,fabrication and characterization of hydraulically-tunable hyperchromatic lenses for two-dimensional(2D)spectrally-resolved spectral *** hyperchromatic lenses,consisting of a positive diffractive lens and a tunable concave lens,are designed to have a large longitudinal chromatic dispersion and the images of different wavelengths from each other.2D objects of different wavelengths can consequently be imaged using the tunability of the lens *** hyperchromatic lens concepts are demonstrated and their spectral characteristics as well as their functionality in spectral imaging applications are shown.

关键词： hyperchromatic lens imaging spectrometer tunable filter tunable lens

Hydrogen Storage Materials Based on Single-Layer Aluminum Nitride Nanostructures

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Chinese Physics Letters 2011年第11期28卷 190-193页

作者： WANG Yu-Sheng YUAN Peng-fe LI Meng SUN Qiang JIA Yu College of Mathematics and Information Science North China University of Water Resources and Electric PowerZhengzhou 450011 Center of Clean energy and Quantum Structures and School of Physics and EngineeringZhengzhou UniversityZhengzhou 450052

Using the first-principles method based on density functional theory,we study the hydrogen storage properties of Li-doped single-layer aluminum nitride nanostructures(AlN).For the pristine AlN sheet,each Al atom adsorbs one H_(2) with an average binding energy of 0.14 eV/H_(2).The hydrogen binding energies and storage capacities can be markedly increased by doping Li atoms onto the AlN *** charge analysis shows that there are charges transferring from the Li atoms to the AlN sheet,thus the charged Li atoms can polarize hydrogen molecules and enhance the interaction between hydrogen molecules and the AlN *** the fully loaded cases,the Li-doped AlN sheet can contain up to 8.25wt%of molecular hydrogen with an average binding energy of 0.20 eV/H_(2).

关键词： hydrogen Storage doping