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mid-term survival of the Optimys short stem: A prospective case series of 500 patients

World journal of Orthopedics 2024年第3期15卷 257-265页

作者： Bryan Hamans Sheryl de Waard Sjoerd Kaarsemaker Esther R C janssen Inger N Sierevelt gino m m j kerkhoffs Daniël Haverkamp Department of Orthopaedic Surgery Xpert ClinicAmsterdam 1101EANetherlands Department of Orthopedic Surgery Amsterdam University Medical CenterAmsterdam 1105 AZNetherlands Esther R C janssen Department of Orthopaedic SurgeryViecuri Medisch CentrumVenlo 5912 BLNetherlands Centre for Orthopaedic Research Spaarne ZiekenhuisHoofddorp 2134 TMNetherlands Department of Orthopaedic Surgery and Sports medicine Amsterdam UMC-Location AMCAmsterdam 1105 AZNetherlands Department of Orthopedic Surgery Xpert Orthopedic Surgery ClinicAmsterdam 1101 EANetherlands

BACKGROUND In recent years,there has been an increase in the number of total hip arthroplasty procedures in the younger patient *** active group has higher expectations of their prosthesis in comparison to the older population,and there is a greater physical demand for the *** femoral stems were in-troduced to retain proximal bone stock and joint biomechanics and became more common to implant in this specific ***,the long-term survival and functional outcomes of various short stems are still being investigated in different *** To determine the 5-year survival of the Optimys hip *** This was a prospective multicenter cohort study of 500 patients conducted in two hospitals in the *** patients received the Optimys short stem(mathys Ltd,Bettlach,Switzerland).The primary outcome measure was survival of the hip stem,with revision as the *** secondary outcome measurements included patient-reported outcome measures(PROms).Kaplan-meier analysis was used to calculate the 5-year survival ***-minus-log transformation was performed to calculate the 95%confidence interval(95%CI).mixed model analyses were performed to assess the course of the PROms during the 1st 2 years after *** were modeled separately for the 1st and 2nd years to calculate the yearly change in PROms during both follow-up periods with accompanying 95%*** The mean age of the total 500 patients was 62.3 years(standard deviation:10.6)and 202 were male(40%).At a median follow-up of 5.5 years(interquartile range:4.5-6.7),7 patients were deceased and 6 revisions were registered,for infection(n=3),subsidence(n=2)and malposition(n=1).This resulted in an overall 5-year survival of 98.8%(95%CI:97.3-99.5).If infection was left out as reason for revision,a stem survival of 99.4%(95%CI:98.1-99.8)was *** questionnaires were completed by 471 patients(94%),317 patients(63%)completed the 1-year follow-up questionna

关键词： Total hip arthroplasty Femoral stem Short stem Optimys Survival 5-year survival Revision PROms

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Can bedside needle arthroscopy of the ankle be an accurate option for intra-articular delivery of injectable agents?

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World journal of Orthopedics 2022年第1期13卷 78-86页

作者： Tobias Stornebrink Sjoerd A S Stufkens Nathaniel P mercer john G Kennedy gino m m j kerkhoffs Department of Orthopedic Surgery Amsterdam UMCUniversity of AmsterdamAmsterdam Movement SciencesAmsterdam 1105AZNetherlands Academic Center for Evidence based Sports medicine Amsterdam 1105AZNetherlands Amsterdam Collaboration for Health and Safety in Sports International Olympic Committee Research Center Amsterdam UMCAmsterdam 1105AZNetherlands Department of Orthopedic Surgery NYU Langone HealthNew YorkNY 10010United States

BACKGROUND Bedside needle arthroscopy of the ankle under local anesthesia has been proposed for intra-articular delivery of injectable *** and tolerability of this approach in the clinical setting–including patients with end-stage ankle pathology and/or a history of prior surgery–is not *** To assess clinical accuracy and tolerability of bedside needle arthroscopy as a delivery system for injectable agents into the tibiotalar *** This was a prospective study that included adult patients who were scheduled for an injection with hyaluronic acid to the tibiotalar *** our center,these injections are used as a last resort prior to extensive *** primary outcome was injection accuracy,which was defined as injecting through the arthroscopic cannula with intra-articular positioning confirmed by a clear arthroscopic view of the joint *** outcome measures included a patientreported numeric rating scale(NRS,0-10)of pain during the procedure and willingness of patients to return for the same *** of ankle pain at rest and during walking was collected at baseline and at 2-wk *** were monitored from inclusion up to a 2-wk control *** We performed 24 ***(46%)participants were male,and mean age was 46.8±14.5 *** was the indication for injection in 20(83%)cases,of which 8(33%)patients suffered from osteoarthritis Kellgren-Lawrence grade IV,and 10(42%)patients from Kellgren-Lawrence grade *** osteochondral defect was the indication for injection in 4(17%)cases.A history of ankle surgery was present in 14(58%)participants and a history of multiple ankle surgeries in 11(46%)*** was possible to confirm accuracy in 21(88%)*** 3(12%)participants where needle arthroscopy did not reach a clear view of the joint space all suffered from Kellgren-Lawrence grade IV *** during the procedure was reported with a median of 1[i

关键词： Ankle arthroscopy NanoScope Needle arthroscopy Injections Proof of concept Patient experience

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Femoroacetabular offset restoration in total hip arthroplasty;Digital templating a short stem vs a conventional stem

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World journal of Orthopedics 2022年第2期13卷 139-149页

作者： Sheryl de Waard Tom Verboom Niels Hendrik Bech Inger N Sierevelt gino m kerkhoffs Daniël Haverkamp Orthopedic Surgery Xpert Orthopedie AmsterdamAmsterdam 1101 EANetherlands Orthopaedic Surgery Academic Medical CentreAmsterdam 1105 AZNetherlands

BACKGROUND Failure in restoring individual anatomy could be a reason for persistent functional limitations post total hip *** offset(FAO)plays an important role in anatomic restoration,as loss of offset≥5 mm is associated with altered gait and decreased functional *** assessment by use of digital templating has shown to be a reliable method for sizing the components in total hip arthroplasty,and can show if anatomic restoration is *** recent years,short stems are growing in popularity as it could allow better restoration due to more variety in *** To assess whether restoration of the FAO differs between a short or a conventional stem by use of digital ***,association of the preoperative offset and caput-colllum-diaphyseal angle(CCD-angle)within restoration of both stems was investigated,and the reliability of measurements was *** A total of 100 standardized hip radiographs were used for digital *** of FAO was classified into“restored”or“not restored”,when amm or≥5 mm difference from baseline value presented,*** between the two stems concerning proportions of correct restoration of the FAO were analyzed by use of mcNemar *** assess association between CCDangle and preoperative FAO with absolute FAO restoration,multi-level analysis was performed by use of a linear mixed model to account for paired *** determination of the optimal point under the curve in operating curve-analysis,bootstrapping of thousand sets was performed to determine the optimal cutoff point of the preoperative FAO for restoration within the limits of 5 *** observers participated for inter-observer reliability,with two observers measuring the radiographs twice for intra-observer *** The mean preoperative FAO was 79.7 mm(range 62.5-113 mm),with a mean CCD-angle of 128.6°(range 114.5°-145°).The conventional stem could only r

关键词： Offset Anatomic offset restoration Total hip arthroplasty Short hip stem Conventional hip stem

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Clinical efficacy of the Ankle Spacer for the treatment of multiple secondary osteochondral lesions of the talus

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World journal of Orthopedics 2022年第2期13卷 178-192页

作者： jari Dahmen j Nienke Altink Gwendolyn Vuurberg Coen A Wijdicks Sjoerd AS Stufkens gino mmj kerkhoffs Department of Orthopedic Surgery Amsterdam UMCLocation AMCAmsterdam 1105AZNetherlands Department of Orthopedic Research ArthrexNaplesFL 34108United States

BACKGROUND The Ankle Spacer was developed as a joint-sparing alternative to invasive endstage ***,there are no clinical studies on the Ankle *** To describe the operative technique and the clinical efficacy of the Ankle Spacer for the treatment of multiple,cystic osteochondral lesions of the talus in patients with failed prior operative *** This is a prospective study during which patients were assessed preoperatively,at 2-and 6 wk,and at 3,6,12 and 24 mo *** with multiple,cystic or large(≥15 mm)osteochondral lesions of the talus after failed prior surgery were *** primary outcome measure was the numeric rating scale(NRS)for pain during walking at 2 years *** outcome measures included the NRS in rest and during stair climbing,the American Orthopaedic Foot and Ankle Society Hindfoot Score,the Foot and Ankle Outcome Score,the Short-Form 36 physical and mental component scale,and the Range of motion(ROm).Radiographic evaluations were conducted to evaluate prosthetic loosening and *** rates and complications were also *** Two patients underwent an Ankle Spacer implantation on the *** NRS during walking improved from 6 and 7 preoperatively to 2 and 2 points postoperatively at 2 years,in patient 1 and 2,*** other patient-reported outcome measures also improved *** were no re-operations nor *** imaging showed no loosening of the implant and no change of implant *** The Ankle Spacer showed clinically relevant pain reduction during walking,improvement in clinical outcomes as assessed with PROms,and no complications or *** treatment option may evolve as a joint-sparing alternative to invasive end-stage surgeries.

关键词： Hemi-arthroplasty Ankle Spacer Talar surface implant Osteochondral lesions of the talus Endstage

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一个很小的界限：基于Dixon-mRI半定量评估的年轻体操运动员和非体操运动员手腕应力性骨髓水肿的发展与验证

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国际医学放射学杂志 2020年第3期 368-369页

作者： L.S.Kox R.B.j.Kraan V.mazzoli m.A.mens G.m.j.j.kerkhoffs A.j.Nederveen 陈家英 Department of Radiology and Nuclear medicine University of Amsterdam Amsterdam Movement Sciences Amsterdam UMC

摘要目的使用基于半定量Dixon-mRI的方法来评估应力相关的干骺端的水分布,进而评估其可靠性和临床实用性,以早期诊断青少年体操运动员的骨骺应力性损伤。方法

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Diagnosing, planning and evaluating osteochondral ankle defects with imaging modalities

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World journal of Orthopedics 2015年第11期6卷 944-953页

作者： Christiaan jA van Bergen Rogier m Gerards Kim Tm Opdam maaike P Terra gino mmj kerkhoffs Department of Orthopedic Surgery Academic Medical Center Department of Radiology Academic Medical Center

This current concepts review outlines the role of diffe-rent imaging modalities in the diagnosis, preoperative planning, and follow-up of osteochondral ankle defects. An osteochondral ankle defect involves the articular cartilage and subchondral bone(usually of the talus) and is mostly caused by an ankle supination trauma. Conventional radiographs are useful as an initial imaging tool in the diagnostic process, but have only moderate sensitivity for the detection of osteochondral defects. Computed tomography(CT) and magnetic resonance imaging(mRI) are more accurate imaging modalities. Recently, ultrasonography and single photon emission CT have been described for the evaluation of osteochondral talar defects. CT is the most valuable modality for assessing the exact location and size of bony lesions. Cartilage and subchondral bone damage can be visualized using mRI, but the defect size tends to be overestimated due to bone edema. CT with the ankle in full plantar flexion has been shown a reliable tool for preoperative planning of the surgical approach. Postoperative imaging is useful for objective assessment of repair tissue or degenerative changes of the ankle joint. Plain radiography, CT and mRI have been used in outcome studies, and different scoring systems are available.

关键词： Cartilage Subchondral bone Imaging Ankle Talus Radiography Computed tomography magnetic resonance imaging Outcome assessment

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Fluctuating temperature modifies heat-mortality association around the globe

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The Innovation 2022年第2期3卷 65-72页

作者： Yao Wu Bo Wen Shanshan Li Antonio Gasparrini Shilu Tong Ala Overcenco Ales Urban Alexandra Schneider Alireza Entezari Ana maria Vicedo-Cabrera Antonella Zanobetti Antonis Analitis Ariana Zeka Aurelio Tobias Barrak Alahmad Ben Armstrong Bertil Forsberg CarmenÍñiguez Caroline Ameling César De la Cruz Valencia ChristoferÅström Danny Houthuijs Do Van Dung Dominic Royé Ene Indermitte Eric Lavigne Fatemeh mayvaneh Fiorella Acquaotta Francesca de’Donato Francesco Sera Gabriel Carrasco-Escobar Haidong Kan Hans Orru Ho Kim Iulian-Horia Holobaca jan Kyselý joana madureira joel Schwartz Klea Katsouyanni magali Hurtado-Diaz martina SRagettli masahiro Hashizume mathilde Pascal micheline de Sousa Zanotti Stagliorio Coélho Noah Scovronick Paola michelozzi Patrick Goodman Paulo Hilario Nascimento Saldiva Rosana Abrutzky Samuel Osorio Tran Ngoc Dang Valentina Colistro Veronika Huber Whanhee Lee Xerxes Seposo Yasushi Honda michelle L.Bell Yuming Guo Department of Epidemiology and Preventive medicine School of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia Climate Air Quality Research UnitSchool of Public Health and Preventive MedicineMonash UniversityMelbourne 3004Australia Department of Public Health Environments and SocietyLondon School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Centre for Statistical methodology London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Centre on Climate Change&Planetary Health London School of Hygiene&Tropical MedicineLondon WC1E 7HTUK Shanghai Children’s medical Centre Shanghai Jiao Tong UniversityShanghai 200025China School of Public Health Institute of Environment and Human HealthAnhui Medical UniversityHefei 230032China Center for Global Health Nanjing Medical UniversityNanjing 211166China School of Public Health and Social Work Queensland University of TechnologyBrisbane 4000Australia National Agency for Public Health of the ministry of Health Labour and Social Protection of the Republic of MoldovaChisinau MD-2009Republic of Moldova Institute of Atmospheric Physics Czech Academy of SciencesPrague 14100Czech Republic Faculty of Environmental Sciences Czech University of Life SciencesPrague 16500Czech Republic Institute of Epidemiology Helmholtz Zentrum M€unchen-German Research Center for Environmental HealthNeuherberg 85747Germany Faculty of Geography and Environmental Sciences Hakim Sabzevari UniversitySabzevar ***Iran Institute of Social and Preventive medicine University of BernBern 3012Switzerland Oeschger Center for Climate Change Research University of BernBern 3012Switzerland Department of Environmental Health Harvard T.H.Chan School of Public HealthHarvard UniversityBostonMA 02115USA Department of Hygiene Epidemiology and Medical StatisticsNational and Kapodistrian University of AthensAthens 11527Greece Institute for Environment Healthand SocietiesBrunel University LondonLondon UB83PNUK Institute of Environmental Assessment and

Studies have investigated the effects of heat and temperature variability(TV)on ***,few assessed whether TV modifies the heat-mortality *** on daily temperature and mortality in the warm season were collected from 717 locations across 36 *** was calculated as the standard deviation of the average of the same and previous days’minimum and maximum temperatures.

关键词： deviation modif heat

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