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抗寄生虫药物

国际药学研究杂志 1984年第1期 29-33页

作者： ginger C D 朱崇泉顾旭初

原虫病2-硝基萘骈[2,1-b.呋喃类化合物对滴虫和内阿米巴的活性等于或优于甲硝哒唑(Metronidazola),而2-硝基苯骈呋喃类仅对内

关键词：利什曼无鞭毛体前鞭毛体细滴型曼氏血吸虫疟疾恶性疟药物抗寄生虫

Design and Fab.ication of ginger Harvesting Machine

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World Journal of Engineering and Technology 2015年第4期3卷 320-338页

作者： M. R. Sanjay G. R. Arpitha L. Laxmana Naik b. Yogesha Department of Mechanical Engineering Malnad College of Engineering Hassan India

ginger is a potential agricultural commodity to b. developed in India. When the harvest comes, people still use a very simple method for harvesting ginger b. using hoes, pick-axe and other farming equipments. The farmers complain for the need of so many work forces for harvesting while the lab.r cost is getting increased and the time spent for harvesting process is too long. Although there is an alternative of imported ginger harvesting machines, those machines are not compatib.e with the farming environment in India, having a high initial and maintenance cost. This machine can b. used in any farming condition in India and can b. prepared at village level. This machine has three main parts namely, ginger digger, screener and power transmission system. This project is focusing on design and fab.ication ginger harvesting machine. The screener will not only separate ginger from soil b.t also not let the ginger get harmed. The screener also uses for collectib.e part, to make this machine need some power transmission system from the engine. This machine needs Auto front petrol engine with rotation speed 20 - 25 rpm approximately with the aid of gear reduction.

关键词： ginger Farming Environment Digger Screener and Power Transmission System

WWOX基因对卵巢癌PE01细胞黏附能力的影响

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中华肿瘤杂志 2009年第6期31卷 414-417页

作者：张洁清李力宋红林 paigeAdam Gab.aHani 广西医科大学肿瘤医院妇瘤科南宁530021 Ovarian Cancer Action Research Centre Imperial CollegeLondon Hammersmith Campus

目的观察WWOX基因转染细胞对卵巢癌PE01细胞黏附能力的影响，并探讨其作用机制。方法利用已构建的WWOX转染细胞、质粒转染细胞及PE01母细胞进行黏附实验，观察不同细胞对纤粘连蛋白（Fn）介导的细胞黏附性。利用整合素仅和b.导的细胞... 详细信息

目的观察WWOX基因转染细胞对卵巢癌PE01细胞黏附能力的影响，并探讨其作用机制。方法利用已构建的WWOX转染细胞、质粒转染细胞及PE01母细胞进行黏附实验，观察不同细胞对纤粘连蛋白（Fn）介导的细胞黏附性。利用整合素仅和b.导的细胞黏附实验，筛选出与卵巢癌细胞黏附有关的整合素。利用筛选出的整合素，进行封闭卵巢癌细胞表面整合素的功能实验，流式细胞检测整合素的表达情况。结果在Fn包被的培养孔中培养2h后，WWOX转染细胞对Fn的细胞黏附性明显低于PE01母细胞和质粒转染细胞（均P〈0．01）。在质粒转染细胞中，整合素以和α3的表达明显高于WWOX转染细胞（均P〈0．05），而整合素β1、β2的表达无明显变化（P〉0．05）；封闭整合素α3后，所有转染细胞对Fn的黏附性明显降低，与非特异性抗体IgG相比，差异有统计学意义（P〈0．05），而封闭整合素以后，与非特异性抗体IgG相比，差异无统计学意义（P〉0．05）。流式细胞检测结果显示，在WWOX转染细胞中，整合素013的表达明显低于质粒转染细胞（P〈0，05）。结论WWOX基因通过调节卵巢癌细胞与细胞外基质的相互作用，降低整合素α3活性，进而降低卵巢癌细胞对Fn介导的黏附性。

关键词：卵巢肿瘤 WWOX基因黏附纤粘连蛋白整合素

Evaluation of Extracts of Native and Non-Native Plant Species for the Suppression of Cogongrass （Imperata cylindrica L.）

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Journal of Agricultural Science and Technology(b. 2011年第3期1卷 347-352页

作者： L. D. Reid O. U. Onokpise J. J. Muchovej C. J. Louime b. G. b.own Agronomy Forestry and Natural Resources Conservation Program College of Engineering Sciences Technology and Agriculture Room 303 South Perry-Paige Building Florida A＆M University Tallahassee Florida 32307 USA Plant Physiology College of Engineering Sciences Technology and Agriculture Florida A＆M University Tallahassee FL 32307 USA

Effects of the extracts of muhly grass （Muhlenb.rgia capillaries Lam.）, chenopodium （Chenopodium amb.osioides L.） and b.ack walnut （Juglans nigra L.） on the growth of cogongrass （Imperata cylindrica L.） were studied. None purified extracts from these plant species were used to evaluate survival, shoot and root growth of cogongrass. Results of plant species extracts on the production of roots, shoot and rhizomes of cogongrass genets and ramets were determined on a weekly b.sis. The extracts significantly reduced the growth and survival of cogongrass when compared to the control. Results indicated that for the in vivo studies, chenopodium extracts, b.ack walnut and muhly grass extracts reduced growth, root and shoot b.omass of cogongrass b. 50 %, 30 % and 41% respectively, compared to control at 8 weeks after planting. These studies indicated plant species with potential for the b.ological control of cogongrass, an invasive species in the Gulf Coast States.

关键词： Cogongrass invasive extracts ramets genets allelopathy.

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流金岁月

现代装饰（家居） 2013年第12期 52-57页

作者： Alessandra b.ldereschi Ariel Zuckerman b.ro Fr Form FORM US WITH LOVE ginger&Jagger Josie Morris KACPER HAMILTON Dan Yeffet&Lucie Koldova Michelle martinazua Nika Zupanc paulloeb.ch Rainer Mutsch 伏平

秋天似乎总是如此的短暂,还没来得及好好地享受秋意,欣赏秋景,取而代之的冬季已经来临。生命的年轮以不可阻挡之0势向前转动着,潺潺流走似水如风般的流金岁月,缓缓飘来永不褪色的甜美回忆,那些真情流淌的心语,如一泓清澈的小溪水,潺潺... 详细信息

秋天似乎总是如此的短暂,还没来得及好好地享受秋意,欣赏秋景,取而代之的冬季已经来临。生命的年轮以不可阻挡之0势向前转动着,潺潺流走似水如风般的流金岁月,缓缓飘来永不褪色的甜美回忆,那些真情流淌的心语,如一泓清澈的小溪水,潺潺欢快地流淌在我的记忆中。很期待下个季节的到来,能看到唯美的童话般的银色世界,更因为它还预示着春天即将到来。圣诞、新年接踵而来,而亮丽又复古的金色饰品是让圣诞节闪耀到底的秘诀,不仅配合了节日的喜庆气氛,同时又彰显出高贵典雅的品味,仿佛将流金岁月轻轻收藏。

关键词：流金岁月高贵典雅如风

Microb.ological safety of spices and their interaction with antib.otics:implications for antimicrob.al resistance and their role as potential antib.otic adjuncts

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Food Quality and Safety 2019年第2期3卷 93-97页

作者： Rachel E.Moore b.Cherie Millar Jayachandran R.Panickar John E.Moore Department of b.cteriology Northern Ireland Public Health LaboratoryBelfast City HospitalLisburn RoadBelfastNorthern IrelandBT97ADUK School of b.omedical Sciences Ulster UniversityCromore RoadColeraineBT521SANorthern IrelandUK Centre for Experimental Medicine Queen’s University97 Lisburn RoadBelfast BT97BLNorthern IrelandUK Department of Paediatrics Sheikh Khalifa Medical CityAbu DhabiUnited Arab Emirates

Ob.ectives:A study was undertaken to:*** contaminating b.cteria on a variety of spices purchased at retail market;*** if spice b.cterial enrichments alter the phenotype of 13 b.cterial foodb.rne and clinical pathogens and 1 prob.otic organism;and *** if spices can alter antimicrob.al activity of seven clinical antib.otics against 16 b.cterial foodb.rne/clinical *** and Methods:Microb.ological examination was undertaken employing 27 spice varieties with four antib.otics and 15 b.cterial ***:b.cteriological contamination levels varied amongst spice varieties,ranging from Kasmin chilli powder(7.5×10^(6)cfu/g;log10^(6).88 cfu/g)to ginger(1.5×10^(4)cfu/g;log_(10)4.18 cfu/g);mean contamination was 1.38×10^(6)cfu/g(log_(10)6.14 cfu/g).Four species within the genus b.cillus were identified(b.cillus megaterium,b.cillus sub.ilis,b.cillus licheniformis,and b.cillus cereus).There was no phenotypic difference with the 14 b.cteria,with b.cterial colony growth/proliferation,pigment production,or with adhesin and mucoid *** of the spice cultures inhib.ted any of the 14 b.cterial species *** the case of doxycycline,amoxicillin,colistin,erythromycin,and piperacillin/tazob.ctam,the zone of inhib.tion increased with the inclusion of the 26 spice varieties,suggesting that the spices were interacting synergistically with the antib.otic,thus making the antib.otic more potent against the b.cteria ***:This study demonstrates a positive interaction b.tween spices and conventional *** the b.rden of antimicrob.al resistance(AMR)worldwide,b.t particularly in South Asian countries(India and Pakistan),any food-related innovation that can help maximize the potency of existing antib.otics is to b. encouraged and *** specific mechanism as to how spices increase the potency of antib.otics needs to b. elucidated,as well as novel food(spice)delivery modalities including novel medicinal foo

关键词： antib.otic resistance antimicrob.al resistance b.cillus foodb.rne pathogen microb.ology Pseudomonas aeruginosa spice

A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues

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The Journal of b.omedical Research 2021年第2期35卷 163-173页

作者： Amy T.Desaulniers Reb.cca A.Cederb.rg Elizab.th P.Carreiro Channab.savaiah b.Gurumurthy b.ett R.White Department of Animal Science University of Nebraska-LincolnLincolnNE 68583-0908USA Department of Pharmacology and Experimental Neuroscience University of Nebraska Medical CenterOmahaNE 68198-5930USA

Since genetic engineering of pigs can b.nefit b.th b.omedicine and agriculture,selecting a suitab.e gene promoter is critically *** cytomegalovirus(CMV)promoter,which can rob.stly drive ub.quitous transgene expression,is commonly used at present,yet recent reports suggest tissue-specific activity in the *** ob.ective of this study was to quantify ZsGreen1 protein(in lieu of CMV promoter activity)in tissues from pigs harb.ring a CMV-ZsGreen1 transgene with a single integration *** samples(n=35)were collected from neonatal hemizygous(n=3)and homozygous(n=3)piglets and ZsGreen1 ab.ndance was determined via ***1 was detected in all tissues,except hypothalamus,kidney cortex and *** expression patterns of homozygous and hemizygous piglets were similar(P>0.05).However,quantification revealed that ZsGreen1 protein levels were *** neural/endocrine tissues,ZsGreen1 ab.ndance was highest in the anterior pituitary gland,intermediate in the cereb.llum and lowest in the cereb.um,spinal cord and posterior pituitary(Pb.ndant in the salivary gland than esophagus,stomach,pancreas,duodenum,jejunum,ileum,spleen,colon,gallb.adder and liver(Pb.rs;Pb.led organs and a valuab.e tool to advance genome editing research.

关键词： gene expression profiling CMV promoter ZsGreen1 b.omedical model genome editing

陈修园《医学实在易》内服复方用药规律复杂网络关联系统综述

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实用中医内科杂志 2018年第9期32卷 16-18页

作者：彭希宸李廷保杨鹏斐甘肃中医药大学中医临床学院兰州730000 甘肃中医药大学中医外科学教研室兰州730000

[主要目的]数据挖掘分析陈修园《医学实在易》内服复方用药规律规律。[资料来源]陈修园《医学实在易》。[选择文献量及依据]纳入药物组成齐全的中药内服复方。排除药名不全的方剂、外用方剂、单味药方、未注明药物组成的方剂。[数据提... 详细信息

[主要目的]数据挖掘分析陈修园《医学实在易》内服复方用药规律规律。[资料来源]陈修园《医学实在易》。[选择文献量及依据]纳入药物组成齐全的中药内服复方。排除药名不全的方剂、外用方剂、单味药方、未注明药物组成的方剂。[数据提炼规则及应用方法]筛选出方剂录入"中医传承辅助系统(V2.5)"。通过该软件"方剂分析"功能,研究组方用药规律;"频次统计"每味药出现频次排序。"规则分析"(支持度个数45,置信度0.8)药物间关联规则,聚类分析核心算法及复杂系统熵聚类分析(相关度8,惩罚度2),挖掘组合新方。[数据综合得出结果与结论]纳入内服复方253首,用药234味。使用频次>15的有23味药,前6位是甘草、茯苓、人参、白术、生姜、当归。药物组合出现频次前3位是"人参+甘草";"白术+甘草";"甘草+茯苓"。无监督熵层次聚类算法得到4个新处方。[未来展望]运用大数据、循证医学理念,强化互联网思维,发挥计算机人工智能作用,结合临床实际分析灵活应用关联规则和聚类研究得到组方规则、核心组合和新处方,能更好、更全面地继承古代名医学术思想及经验。

关键词：用药规律陈修园医学实在易内服复方老中医经验中医传承辅助系统(V2.5) 复杂网络关联无监督熵层次聚类算法使用频次循证医学系统综述

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姜渣-玉米淀粉膜的制备及研究

包装工程 2018年第23期39卷 93-99页

作者：谢玮崔少宁肖川张雪李颖烟台南山学院食品系烟台265713 烟台南山学院工学院烟台265713 宁夏大学银川750021

目的制备一种纯天然的、具有抑菌性的可食用淀粉膜。方法以玉米淀粉为原料,通过添加适量的姜渣、甘油、羧甲基纤维素钠,采用流延法制备姜渣-玉米淀粉膜。结果当淀粉的质量分数为3%,甘油的质量分数为1%,姜渣的质量分数为0.4%时,膜的透光... 详细信息

目的制备一种纯天然的、具有抑菌性的可食用淀粉膜。方法以玉米淀粉为原料,通过添加适量的姜渣、甘油、羧甲基纤维素钠,采用流延法制备姜渣-玉米淀粉膜。结果当淀粉的质量分数为3%,甘油的质量分数为1%,姜渣的质量分数为0.4%时,膜的透光性、透油性、水蒸气透过性、溶解度、溶胀度等各项指标的综合测定结果较好。生姜中含有姜辣素、姜油等活性成分,添加姜渣可作为天然的抑菌剂,微生物试验结果证实,姜渣-玉米淀粉膜对霉菌和酵母菌具有一定抑菌作用,且抑菌效果与姜渣的含量成正比关系。结论所制备姜渣-玉米淀粉的结构紧密、光滑平整,并具有一定的抑菌性。

关键词：玉米淀粉姜渣制备工艺抑菌