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Polyetheretherketone and titanium surface treatments to modify roughness and wettability–Improvement of bioactivity and antibacterial properties

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Journal of Materials Science & Technology 2021年第36期95卷 213-224页

作者： Davide Porrelli Mario Mardirossian Nicola Crapisi Marco Urban Nicola Andrea Ulian Lorenzo Bevilacqua gianluca turco Michele Maglione Department of Medical Surgical and Health SciencesUniversity of TriestePiazza dell'Ospitale 134129TriesteItaly

Among the materials available for implant production,titanium is the most used while polyetheretherketone(PEEK)is emerging thanks to its stability and to the mechanical properties similar to the ones of the bone *** surface properties like roughness and wettability play a paramount role in cell adhesion,cell proliferation,osteointegration and implant ***,the bacterial adhesion to the biomaterial and the biofilm formation depend on surface smoothness and *** this work,two different treatments,sandblasting and air plasma,were used to increase respectively roughness and wettability of two materials:titanium and *** effects were analyzed with profilometry and contact angle *** biological properties of the material surfaces were also investigated in terms of cell adhesion and proliferation of NIH-3T3 cells,MG63 cells and human Dental Pulp Stem ***,the ability of Staphylococcus aureus to adhere and form a viable biofilm on the samples was *** biological properties of both treatments and both materials were compared with samples of Synthegra;titanium,which underwent laser ablation to obtain a porous micropatterning,characterized by a smooth surface to discourage bacterial *** cell types used were able to adhere and proliferate on samples of the tested *** adhesion was higher on sandblasted PEEK samples for both MG63 and NIH-3T3 cell lines,on the contrary,the highest proliferation rate was observed on sandblasted titanium and was only slightly dependent on wettability;h DPSCs were able to proliferate similarly on sandblasted samples of both tested *** highest osteoblast differentiation was observed on laser micropatterned titanium samples,but similar effects,even if limited,were also observed on both sandblasted materials and air plasma treated *** lowest bacterial adhesion and biofilm formation was observed on micropatterned titanium samples whereas,the

关键词： PEEK Titanium Micropatterning Roughness Wettability Differentiation

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