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A novel solution treatment and aging for powder bed fusion-laser beam Ti-6Al-2Sn-4Zr-6Mo alloy:Microstructural and mechanical characterization

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 414-424页

作者： gianluca Pirro Alessandra Martucci Alessandro Morri Mariangela Lombardi Lorella Ceschini Department of Industrial Engineering(DIN) Alma Mater Studiorum-University of BolognaBologna 40136Italy Department of Applied Science and Technology(DISAT) Politecnico di TorinoTorino TO 10129Italy

Ti-6Al-4Zr-2Sn-6Mo alloy is one of the most recent titanium alloys processed using powder bed fusion-laser beam(PBF-LB)*** alloy has the potential to replace Ti-6Al-4V in automotive and aerospace applications,given its superior mechanical properties,which are approximately 10%higher in terms of ultimate tensile strength(UTS)and yield strength after appropriate heat *** as-built conditions,the alloy is characterized by the presence of soft orthorhombicα″martensite,necessitating a postprocessing heat treatment to decompose this phase and enhance the mechanical properties of the ***,PBFed Ti6246 components undergo an annealing process that transforms theα″martensite into anα-βlamellar *** primary objective of this research was to develop a solution treatment and aging(STA)heat treatment tailored to the unique microstructure produced by the additive manufacturing process to achieve an ultrafine bilamellar microstructure reinforced by precipitation *** study investigated the effects of various solution temperatures in theα-βfield(ranging from 800 to 875℃),cooling media(air and water),and aging time to determine the optimal heat treatment parameters for achieving the desired bilamellar *** each heat treatment condition,differentα-βmicrostructures were found,varying in terms of theα/βratio and the size of the primaryα-phase *** attention was given to how these factors were influenced by increases in solution temperature and how microhardness correlated with the percentage of the metastableβphase present after *** tests were performed on samples subjected to the most promising heat treatment parameters.A comparison with literature data revealed that the optimized STA treatment enhanced hardness and UTS by13%and 23%,respectively,compared with those of the annealed *** surface analyses were conducted to investigate fracture mechanisms.

关键词： powder bed fusion-laser beam titanium alloys heat treatments mechanical properties fractographic analysis

Identification of new genetic risk factors for prostate cancer

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Asian Journal of Andrology 2009年第1期11卷 49-55页

作者： Michelle Guy Zsofia Kote-Jarai Graham G. Giles Ali Amin Al Olama Sarah K. Jugurnauth Shani Mulholland Daniel A. Leongamomlert Stephen M. Edwards Jonathan Morrison Helen I. Field Melissa C. Southey gianluca severi Jenny L. Donovan Freddie C. Hamdy David R Dearnaley Kenneth R. Muir Charmaine Smith Melisa Bagnato Audrey T. Ardern-Jones Amanda L. Hall Lynne T. O＇Brien Beatrice N. Gehr-Swain Rosemary A. Wilkinson Angela Cox Sarah Lewis Paul M. Brown Sameer G. Jhavar Malgorzata Tymrakiewicz Artitaya Lophatananon Sarah L. Bryant The UK Genetic Prostate Cancer Study Collaborators British Association of Urological Surgeons＇ Section of Oncology and The UK ProtecT Study Collaborators Alan Horwich Robert A. Huddart Vincent S. Khoo Christopher C. Parker Christopher J. Woodhouse Alan Thompson Tim Christmas Chris Ogden Cyril Fisher Charles Jameson Colin S. Cooper Dallas R. English John L. Hopper David E. Neal Douglas E Easton Rosalind A. Eeles Section of Cancer Genetics The Institute of Cancer Research Sutton Surrey SM2 5NG UK Cancer Epidemiology Centre The Cancer Council Victoria Carlton VIC 3053 Australia Centre for Molecular Environmental Genetic and Analytic Epidemiology The University of Melbourne Carlton VIC 3053 Australia Cancer Research UK Genetic Epidemiology Unit University of Cambridge Strangeways Laboratory Worts Causeway Cambridge CB1 8RN UK Department of Oncology University of Cambridge Strangeways Laboratory Worts Causeway Cambridge CB1 8RN UK Genetic Epidemiology Laboratory Department of Pathology The University of Melbourne Parkville VIC 3052 Australia Department of Social Medicine University of Bristol Bristol BS8 2PR UK Academic Urology Unit University of Sheffield Sheffield SIO 2JF UK The Royal Marsden NHS Foundation Trust Sutton Surrey SM2 5PT and London SW3 6JJ UK University of Nottingham Medical School Queens Medical Centre Nottingham NG7 2UH UK Institute for Cancer Studies University of Sheffield Sheffield SIO 2RX UK Surgical Oncology （Uro-Oncology S4） Departments of Oncology and Surgery University of Cambridge Addenbrooke＇s Hospital Cambridge CB2 2QQ UK A full list of authors is provided in the Supplementary Note online Ka Shing Centre Cambridge CB2 ORE UK Cancer Research UK Cambridge Research Institute Li Ka Shing Centre Cambridge CB2 ORE UK.

There is evidence that a substantial part of genetic predisposition to prostate cancer （PCa） may be due to lower penetrance genes which are found by genome-wide association studies. We have recently conducted such a study and seven new regions of the genome linked to PCa risk have been identified. Three of these loci contain candidate susceptibility genes： MSMB, LMTK2 and KLK2/3. The MSMB and KLK2/3 genes may be useful for PCa screening, and the LMTK2 gene might provide a potential therapeutic target. Together with results from other groups, there are now 23 germline genetic variants which have been reported. These results have the potential to be developed into a genetic test. However, we consider that marketing of tests to the public is premature, as PCa risk can not be evaluated fully at this stage and the appropriate screening protocols need to be developed. Follow-up validation studies, as well as studies to explore the psychological implications of genetic profile testing, will be vital prior to roll out into healthcare.

关键词： prostate cancer genetics susceptibility loci SNPs relative risks

A novel way to study the nuclear collective excitations

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Nuclear Science and Techniques 2023年第12期34卷 109-111页

作者： gianluca Colò Dipartimento di Fisica“Aldo Pontremoli” Universitàdegli Studi di MilanoVia Celoria 1620133 MilanoItaly INFN Sezione di MilanoVia Celoria 1620133 MilanoItaly

Typically, the unambiguous determination of the quantum numbers of nuclear states is a challenging task. Recently, it has been proposed to utilize to this aim vortex photons in the MeV energy region and, potentially, this could revolutionize nuclear spectroscopy because of the new and enhanced selectivity of this probe. Moreover, nuclei may become diagnostic tools for vortex photons. Still, some open questions have to be dealt *** exhibit intricate excitation spectra. Indeed, not all states within these spectra are equally significant. Some are not sensitive to specific terms in the nuclear Hamiltonian or do not display novel features, so that investigating them is not helpful to enhance our overall understanding of nuclear structure. On the other hand, there are states that manifest themselves as prominent peaks, e.g., in the inelastic scattering spectra. Among the best examples are the so-called Giant Resonances that lie at energies of the order of tens of MeV [1].

关键词： spectra structure excitation

Heavy ion induced charge exchange reactions: A preliminary study within the Constrained Molecular Dynamics model

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Chinese Physics C 2021年第8期45卷 105-109页

作者： gianluca Giuliani School of Nuclear Science and Technology Lanzhou UniversitySouth Tianshui Road222Lanzhou 730000China

We present a preliminary study of charge exchange heavy ion induced reactions based on the constrained molecular dynamics(CoMD)*** purpose is to test the capability of the model in predicting the occurrence of single charge exchange(SCE)and double charge exchange(DCE)exit channels for three different en-trance channels at the same laboratory incident *** nuclear reaction dynamics and nuclear interaction within the CoMD approach are the only ingredients that have given,at this stage,promising results for SCE and DCE cross section *** obtained results suggest an upgrade and possible future employment of the model for studies relating to the production of exotic nuclei through charge exchange reactions or DCE reactions and their connection with neutrinoless double beta decay.

关键词： nuclear physics nuclear reactions molecular dynamics

Non-destructive OAM measurement via light-matter interaction

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Light(Science & Applications) 2022年第3期11卷 10-12页

作者： gianluca Ruffato Department of Physics and Astronomy‘G.Galilei’ University of PadovaPadovaItaly Quantum Technologies Research Center(QTech) University of PadovaPadovaItaly

The detection of orbital angular momentum usually relies on optical techniques,which modify the original beam to convert the information carried on its phase into a specific intensity distribution in ***,the exploitation of high-intensity beams can result destructive for standard optical elements and setups.A recent publication suggests a solution to overcome all those limitations,by probing highly-intense vortex pulses with a structured reference beam in a strong-field photoionization process.

关键词： beam overcome interaction

Yan Theorem in L~∞ with Applications to Asset Pricing

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Acta Mathematicae Applicatae Sinica 2007年第4期23卷 551-562页

作者： gianluca Cassese University of Lugano via G.Buffi 13CH-6904 LuganoSwitzerland and Università del Salento

We prove an L∞ version of the Yan theorem and deduce from it a necessary condition for the absence of free lunches in a model of financial markets, in which asset prices are a continuous R^d valued process and only simple investment strategies are admissible. Our proof is based on a new separation theorem for convex sets of finitely additive measures.

关键词： Arbitrage free lunch fundamental theorem of asset pricing martingale measure Yan theorem

Should we consider patent foramen ovale and secundum atrial septal defect as different steps of a single anatomo-clinical continuum？

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Journal of Geriatric Cardiology 2014年第3期11卷 177-179页

作者： gianluca Rigatelli Section of Adult Congenital and Adult Heart Disease Cardiovascular Diagnosis and Endoluminal Interventions Rovigo General Hospital Rovigo 45100

1 Introduction Isolated atrial septal defects （ASD） represent 7% of all cardiac anomalies and can present at any age. Adolescents and adults with simple congenital heart disease such as isolated atrial septal defects are more likely to reach adult age without being diagnosed. Secundum ASD （sASD） is by far the most common type, occurring in 1/1500 live births, with 65% to 75% involving females, On the other hand, patent foramen ovale （PFO） represents an endemic variant in the normal population with a prevalence of 25%-27%. These two entities appear so different that is difficult to fred a conjunction ring： nevertheless we use the same philosophy for the treatment, Indeed, device-based closure has been proved to be effective in both settings.

关键词： Anatomy Atrial septal defect Echocardiography Patent foramen ovale

OAM-inspired new optics:the angular metalens

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Light(Science & Applications) 2021年第6期10卷 944-946页

作者： gianluca Ruffato Department of Physics and Astronomy‘G.Glilei’ Universitof PadovaPadovaItaly

Analogous to the behavior of a common converging lens for the input of tilted waves,a recent publication suggests a new optical element with an azimuthal-quadratic phase profile for the focusing of orbital angular momentum beams at distinct angular *** realization in a metasurface form enables the combined measurement of orbital and spin angular momentum using a single optical component.

关键词： angular momentum orbital

Effect of operating temperature on aged single lap bonded joints

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Defence Technology（防务技术） 2020年第2期16卷 283-289页

作者： Costanzo Bellini gianluca Parodo Luca Sorrentino Department of Civil and Mechanical Engineering University of Cassino and Southern LazioCassino FR03043Italy

In recent decades,designers have increasingly focused on the stability of assemblies in composite materials over time,particularly when used in structural *** use of structural adhesives allows for realising assemblies without mechanical *** fact,bonding is an assembly technique that prevent corrosion,ensures uniform stresses in the joint,and grows the specific resistance of the *** knowledge of the behaviour of bonded joint is necessary to ensure the reliability of this technique over time,especially in aggressive *** aim of this wo rk consists in investigating the combined effect of hydrothermal ageing and temperature test on the lap shear strength of single lap joints realised in *** results showed a higher influence of the ageing on paste adhesive compared to film ***,the ageing,combined with the operating temperature,played a fundamental role on the shear strength of the bonded joints.

关键词： Temperature tests Hydrothermal ageing Adhesive bonding Single lap joint Experimental tests