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Sensing in the presence of strong noise by deep learning of dynamic multimode fiber interference

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Photonics Research 2021年第4期9卷 I0029-I0038页

作者： linh V.nguyen Cuong C.nguyen Gustavo Carneiro Heike Ebendorff-Heidepriem Stephen C.Warren-Smith Institute for Photonics and Advanced Sensing and School of Physical Sciences The University of AdelaideAdelaideSA 5005Australia Australian Institute for Machine Learning The University of AdelaideAdelaideSA 5005Australia Australian Research Council Centre of Excellence for Nanoscale BioPhotonics The University of AdelaideSA 5005Australia Future Industries Institute University of South AustraliaMawson LakesSA 5095Australia

A new approach to optical fiber sensing is proposed and demonstrated that allows for specific measurement even in the presence of strong noise from undesired environmental perturbations.A deep neural network model is trained to statistically learn the relation of the complex optical interference output from a multimode optical fiber(MMF)with respect to a measurand of interest while discriminating the *** technique negates the need to carefully shield against,or compensate for,undesired perturbations,as is often the case for traditional optical fiber *** is achieved entirely in software without any fiber postprocessing fabrication steps or specific packaging required,such as fiber Bragg gratings or specialized *** technique is highly generalizable,whereby the model can be trained to identify any measurand of interest within any noisy environment provided the measurand affects the optical path length of the MMF’s guided *** demonstrate the approach using a sapphire crystal optical fiber for temperature sensing under strong noise induced by mechanical vibrations,showing the power of the technique not only to extract sensing information buried in strong noise but to also enable sensing using traditionally challenging exotic materials.

关键词： fiber sapphire noise

Lexical Collocations of “EAT” and “WEAR” in American English from 1800 to 2000:A Corpus-Based Study of Sociolinguistics Approach

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外语教育 2017年第1期 79-90页

作者： Tran Dieu linh nguyen Thi Thu Thuy Wuhan University of Technology—School of Foreign Languages Huazhong University of Science and Technology—School of Foreign Languages

Collocations transmit cultural and societal meanings and stereotypes which have built up over time;therefore,research of collocations,especially lexical collocations,provides particular insights into *** present study examines verb-noun lexical collocations of'eat'and'wear'between 1800 and 2000 through three corpora:Corpus of Historical American English(COHA),Corpus of Contemporary American English(COCA)and Google Books(American).Whilst exploring possible semantic changes in the use of these two verbs,the author seeks for the explanation of the alternative of old collocations and the appearance of new *** is found that there is not much fluctuation in the meaning of'eat'and'wear'after two ***,it also reveals that social changes have had great impacts on language changes which can modify or create new collocations in the verbnoun lexical collocation of'eat'and 'wear'.By means of identifying the syntagmatic and paradigmatic properties of verb-noun lexical collocation of'eat'and 'wear',it is clearly shown that corpus has potential applications in translation studies,language teaching,and other scientific fields.

关键词： corpus-based study sociolinguistics verb-noun lexical collocations American English

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改革开放后越南的通货膨胀研究

改革开放后越南的通货膨胀研究

作者： nguyen THUY linh 宁波大学

学位级别：硕士

论文“改革开放后越南的研究通货膨胀研究”集中于在理论和实践分析越南和世界上的通货膨胀,着力分析自从1986年越南改革开放以后出现的通货膨胀产生的原因以及治理。本文主要解决了以下四个方面：一是通货膨胀成为整个世界一个热闹的话... 详细信息

论文“改革开放后越南的研究通货膨胀研究”集中于在理论和实践分析越南和世界上的通货膨胀,着力分析自从1986年越南改革开放以后出现的通货膨胀产生的原因以及治理。本文主要解决了以下四个方面：一是通货膨胀成为整个世界一个热闹的话题,当然在越南同样是一个热闹的话题。二是引致越南通货膨胀的原因。引致越南通货膨胀的首要原因是越南政府的决策失误,出现了大量的财政赤字;其次是越南国家银行没有权力去独立地调整货币政策,从而导致政策有时无效,甚至于对经济有害。国内生产仍然不能满足国内的需要,从而依赖于进口,导致也存在着输入型通货膨胀。三是分析在不同时期采用不同政策治理通货膨胀和解决经济问题的政策效果。文章分析发现越南在不同时期采用不同的政策治理通货膨胀或者通货紧缩,例如汇率政策、利率政策、货币供给政策和财政政策。但仍然存在着以下问题：过紧的货币供给、政策效果时滞、越南盾贬值等等……。四是文章提出了在今后治理通货膨胀、促进经济增长的对策建议：极端审慎的财政政策、审慎使用的货币政策、银行体系改革和调整汇率政策。尽管本文已经对改革开放后越南通货膨胀的研究有了一定的进展,但随着世界经济一体化的进程,通货膨胀将会成为未来更迫切的课题。因此,我希望这篇文章有益于越南通货膨胀理论和宏观经济的研究。

关键词：通货膨胀需求拉动的通货膨胀成本推动型通货膨胀货币通胀控制通胀

Predicted aerodynamic damping of slender single beam structures in across-wind vibrations

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Acta Mechanica Sinica 2020年第5期36卷 990-998,I0001页

作者： Cung Huy nguyen Dinh Tung nguyen Department of Civil Engineering Industrial University of Ho Chi Minh CityHo Chi Minh City 700000Vietnam Department of Civil Engineering University of NottinghamNottingham NG72RDUK

The paper presents a generalization of the conventional analytical approach where the quasisteady theory is utilised to evalu-ate the across-wind aerodynamic damping of slender single beam *** generalized theory considers the variation of structural and aerodynamic parameters along the structural height,together with the nature of the vertical wind profile and mode ***-form solutions for typical uniform and tapered tall buildings are given.A numerical application on a prototype tall building shows that the conventional method may be oversimplified,which results in incorrect predictions of the aerodynamic damping.

关键词： Aerodynamic damping Across-wind Slender structure-Galloping Tall building

Brain endothelial cell-derived extracellular vesicles with a mitochondria-targeting photosensitizer effectively treat glioblastoma by hijacking the blood-brain barrier

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Acta Pharmaceutica Sinica B 2023年第9期13卷 3834-3848页

作者： Thuy giang nguyen Cao Ji Hee Kang Su Jin Kang Quan Truong Hoang Han Chang Kang Won Jong Rhee Yu Shrike Zhang Young Tag Ko Min Suk Shim Division of Bioengineering Incheon National UniversityIncheon 22012Republic of Korea College of Pharmacy Gachon UniversityIncheon 21936Republic of Korea Department of Pharmacy Integrated Research Institute of Pharmaceutical Sciencesand BK21 PLUS Team for Creative Leader Program for Pharmacomics-based Future PharmacyCollege of Pharmacythe Catholic University of KoreaGyeonggi-do 14662Republic of Korea Research Center for Bio Materials&Process Development Incheon National UniversityIncheon 22012Republic of Korea Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolCambridgeMA 02139USA

Glioblastoma(GBM)is the most aggressive malignant brain tumor and has a high mortality *** therapy(PDT)has emerged as a promising approach for the treatment of malignant brain ***,the use of PDT for the treatment of GBM has been limited by its low blood-brain barrier(BBB)permeability and lack of cancer-targeting ***,brain endothelial cell-derived extracellular vesicles(bEVs)were used as a biocompatible nanoplatform to transport photosensitizers into brain tumors across the *** enhance PDT efficacy,the photosensitizer chlorin e6(Ce6)was linked to mitochondria-targeting triphenylphosphonium(TPP)and entrapped into *** Ce6(TPP-Ce6)selectively accumulated in the mitochondria,which rendered brain tumor cells more susceptible to reactive oxygen species-induced apoptosis under light ***,the encapsulation of TPP-Ce6 into b EVs markedly improved the aqueous stability and cellular internalization of TPP-Ce6,leading to significantly enhanced PDT efficacy in U87MG GBM *** in vivo biodistribution study using orthotopic GBM-xenografted mice showed that b EVs containing TPP-Ce6[b EV(TPP-Ce6)]substantially accumulated in brain tumors after BBB penetration via transferrin receptor-mediated *** such,b EV(TPP-Ce6)-mediated PDT considerably inhibited the growth of GBM without causing adverse systemic toxicity,suggesting that mitochondria are an effective target for photodynamic GBM therapy.

关键词： Extracellular vesicle Chlorin e6 Triphenylphosphonium Mitochondria-targeting photosensitizer Photodynamic therapy Blood-brain barrier Glioblastoma Transferrin receptor

Potential Forecast of Graphite ore Resources in Van Yen Area,Yen Bai

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Journal of Geological Resource and Engineering 2021年第2期9卷 51-60页

作者： Chi Cong nguyen Xuan Truong Tran Khac Hoang giang nguyen Thi Phuong Thanh nguyen Hanoi University of Natural Resources and Environment Hanoi 100000Vietnam

Van Yen district,Yen Bai province belongs to the Red River zone,which is a promising area for graphite ore,however,the methodologies were applied to previous research,evaluation and forecast potential of graphite are still *** on that reason,this paper introduces a method to forecast prospective zoning by using mathematical methods,remote sensing combined with GIS(geographic information system)*** results of the study are an important basis in research orientation,in mineral exploration and exploitation in a reasonable way in order to meet the demand of the graphite raw materials for domestic and industries abroad.

关键词： Graphite ore resources Van Yen ANN

Transient responses of double-curved sandwich two-layer shells resting on Kerr's foundations with laminated three-phase polymer/GNP/fiber surface and auxetic honeycomb core subjected to the blast load

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Defence Technology（防务技术） 2024年第5期35卷 222-247页

作者： nguyen Thi Hai Van Thi Hong nguyen Researcher&Lecturer Faculty of Industrial EducationThe University of Danang-University of Technology and Education48 Cao ThangDanang550000Viet Nam Researcher&Lecturer Faculty of Mechanical EngineeringThuyloi University175 Tay SonDong DaHanoi100000Viet Nam

This work uses refined first-order shear theory to analyze the free vibration and transient responses of double-curved sandwich two-layer shells made of auxetic honeycomb core and laminated three-phase polymer/GNP/fiber surface subjected to the blast *** of the two layers that make up the double-curved shell structure is made up of an auxetic honeycomb core and two laminated sheets of three-phase polymer/GNP/*** exterior is supported by a Kerr elastic foundation with three *** key innovation of the proposed theory is that the transverse shear stresses are zero at two free surfaces of each *** contrast to previous first-order shear deformation theories,no shear correction factor is ***'s exact solution was used to treat the double-curved shell problem with a single title boundary,while the finite element technique and an eight-node quadrilateral were used to address the other boundary *** ensure the accuracy of these results,a thorough comparison technique is employed in conjunction with credible *** problem model's edge cases allow for this kind of *** study's findings may be used in the post-construction evaluation of military and civil works structures for their ability to sustain explosive *** addition,this is also an important basis for the calculation and design of shell structures made of smart materials when subjected to shock waves or explosive loads.

关键词： Blast load Two-layer shell Polymer/GNP/Fiber surface Auxetic honeycomb Shear connectors

Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection

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World Journal of Gastroenterology 2018年第2期24卷 248-256页

作者： Bui Tien Sy Nghiem Xuan Hoan Hoang Van Tong Christian G Meyer nguyen linh Toan Le Huu Song Claus-Thomas Bock Thirumalaisamy P Velavan Vietnamese-German Center of Excellence in Medical Research HanoiVietnam Institute of Clinical Infectious Diseases 108 Military Central HospitalHanoiVietnam Institute of Tropical Medicine University of TübingenTübingen 72074Germany Department of Infectious Diseases Robert Koch InstituteBerlin 13302Germany Department of Pathophysiology Vietnam Military Medical UniversityHanoiVietnam

AIM To investigate possible effects of IRF5 polymorphisms in the 3' UTR region of the IFR5 locus on susceptibilityto hepatitis B virus(HBV) infection and progression of liver diseases among clinically classified Vietnamese *** Four IFR5 SNPs(rs13242262 A/T, rs77416878 C/T, rs10488630 A/G, and rs2280714 T/C) were genotyped in clinically classified HBV patients [chronic hepatitis B(CHB). n = 99; liver cirrhosis(LC), n = 131; hepatocellular carcinoma(HCC), n = 149] and in 242 healthy controls by direct sequencing and Taq Man realtime PCR assays. RESULTS Comparing patients and controls, no significant association was observed for the four IFR5 variants. However, the alleles rs13242262 T and rs10488630 G contributed to an increased risk of liver cirrhosis(LC vs CHB: OR = 1.5, 95%CI: 1.1-2.3, adjusted P = 0.04; LC vs CHB: OR = 1.7, 95%CI: 1.1-2.6, adjusted P = 0.019). Haplotype IRF5*TCGT constructed from 4 SNPs was observed frequently in LC compared to CHB patients(OR = 2.1, 95%CI: 1.2-3.3, adjusted P = 0.008). Haplotype IRF5*TCAT occurred rather among CHB patients than in the other HBV patient groups(LC vs CHB: OR = 0.4, 95%CI: 0.2-0.8, adjusted P = 0.03; HCC vs CHB: OR = 0.3, 95%CI: 0.15-0.7, adjusted P = 0.003). The IRF5*TCAT haplotype was also associated with increased levels of ALT, AST and bilirubin. CONCLUSION Our study shows that IFR5 variants may contribute as a host factor in determining the pathogenesis in chronic HBV infections.

关键词： hepatitis B virus infection Liver diseases IRF5 IFR5 polymorphisms IFR5 haplotypes