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The Doppelgänger phenomenon and death:a peculiar case of homicide by a subject with first-episode psychosis

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Forensic Sciences Research 2022年第4期7卷 798-802页

作者： Cristiano Barbieri Gabriele Rocca Caterina Bosco Lucia Tattoli Ignazio Grattagliano giancarlo Di Vella Section of Forensic Medicine and Forensic Sciences University of PaviaPaviaItaly Department of Health Sciences University of GenoaGenoaItaly S.C.Medicina Legale U A.O.U.Cittàdella Salute e della Scienza di TorinoTurinItaly Department of Education PsychologyCommunication University Aldo Moro of BariBariItaly Department of Public Health and Pediatric Sciences Legal Medicine UnitUniversity of TurinTurinItaly

The Doppelgänger phenomenon refers to the experience of a direct encounter with one’s self,characteriswed by:(i)the perception of a figure with one’s own identical physical features;or(ii)the apprehension that the perceived figure shares the same personality and *** Doppelgänger does not only look like the same person,it is his/her *** perceptual element is usually a hallucination,although occasionally a false perception of an actual figure may be *** phenomenon has been described in individuals suffering from overwhelming fear,severe anxiety or intoxication,epilepsy,as well as in the sleep-wakefulness *** has also been reported in major *** fear of imminent death often precedes the Doppelgänger *** report presents the case of a 30-year-old man,Mr.Y,who was stabbed to death by Mr.X,his“double”.The aggressor and his victim,although not related,were truly doubles;remarkably,they shared the same name and surname,age,professional activity and place of ***,they attended the same sports center but barely knew each *** forensic psychiatric evaluations in Mr.X,subsequent to the crime committed,were suggestive of a psychotic *** case is unique in the scientific *** the most serious psychotic forms,the issue of the“double”calls into question not only the dissociative processes involved in the etiopathogenesis of the disorder,but also bio-psycho-social elements,as well as personal data in this case,which made the victim and the aggressor“identical”.In the context of psychopathological functioning,the delusional mood(Wahnstimmung)that precedes the development of delirium is a sort of gateway to an impending psychotic illness,involving delusional awareness or mood(atmosphere).In psychosis,splitting is the main issue and this influence is seen as an evil,foreign,apocalyptic and unknown side no longer recognised as belonging to the self even in a physical *** such a situation,it is

关键词： Forensic sciences forensic psychiatry homicide first-episode psychosis Doppelgänger delusional disorder criminal responsibility

Pemphigoid Gestational and the Importance of Differential Diagnosis: A Case Report

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Open Journal of Obstetrics and Gynecology 2022年第11期12卷 1129-1133页

作者： Gabriela Francoes Rostirolla Carolina dalla Santa dal moro Karine Cappelletti Mariana Moreira Rizzolli Marília Damo Patrícia Borchardt Bolson Taciana Cappelletti Thaís Hunoff Ribeiro Universidade de Caxias do Sul Caxias do Sul Brazil

Pemphigoid Gestational (PG), an uncommon autoimmune bullous dermatosis of pregnancy, stands out between the specific dermatological diseases of the gestational period. Despite being self-limited and benign, it has a significant impact on women’s health, both physiologically and psychologically. In addition, it promotes pathological changes that can be complicated during pregnancy. This paper reports the case of a pregnant patient with blistering lesions throughout the whole body. The diagnostic hypothesis initially involved PG and the specific treatment with corticosteroids was initiated, but after the anatomopathological result of the biopsy there has been diagnostic confusion with drug hypersensitivity, since clinical and histological manifestations were exuberant for both pathologies. As the lesions recurred in the puerperium, due to the corticoid abstention that was administered for the treatment of the differential diagnosis, a diagnostic review with immunofluorescence was made and confirmed PG. It is important to establish a correct diagnosis therefore, in order to improve the quality of care offered to the mother-baby binomial.

关键词： Pemphigus Pregnancy Dermatology

Geo-environmental parametric 3D models of SARS-CoV-2 virus circulation in hospital ventilation systems

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Geoscience Frontiers 2022年第6期13卷 244-256页

作者： Carla Gabriela Carlot Zorzi Alcindo Neckel Laércio Stolfo Maculan Grace Tibério Cardoso Leila dal moro Alexandre Almeida Del Savio Leopoldo D.Z.Carrasco Marcos L.S.Oliveira Eliane Thaines Bodah Brian William Bodah Faculdade Meridional IMED304-Passo Fundo-RS 99070-220Brazil Universidad de Lima Avenida Javier Prado Este 4600–Santiago de Surco 1503Peru Department of Civil and Environmental.Universidad de la Costa CUCCalle 58#55–66BarranquillaAtlánticoColombia State University of New York Onondaga Community College4585 West Seneca TurnpikeSyracuseNY 13215USA Thaines and Bodah Center for Education and Development 840 South Meadowlark LaneOthelloWA 99344USA

The novel coronavirus, SARS-CoV-2, has the potential to cause natural ventilation systems in hospital environments to be rendered inadequate, not only for workers but also for people who transit through these environments even for a limited duration. Studies in of the fields of geosciences and engineering,when combined with appropriate technologies, allow for the possibility of reducing the impacts of the SARS-CoV-2 virus in the environment, including those of hospitals which are critical centers for healthcare. In this work, we build parametric 3D models to assess the possible circulation of the SARS-CoV-2 virus in the natural ventilation system of a hospital built to care infected patients during the COVID-19 pandemic. Building Information Modeling(BIM) was performed, generating 3D models of hospital environments utilizing Revit software for Autodesk CFD 2021. The evaluation considered dimensional analyses of 0°, 45°, 90° and 180°. The analysis of natural ventilation patterns on both internal and external surfaces and the distribution of windows in relation to the displacement dynamics of the SARS-CoV-2 virus through the air were considered. The results showed that in the external area of the hospital, the wind speed reached velocities up to 2.1 m/s when entering the building through open windows. In contact with the furniture, this value decreased to 0.78 m/s. In some internal isolation wards that house patients with COVID-19, areas that should be equipped with negative room pressure, air velocity was null. Our study provides insights into the possibility of SARS-CoV-2 contamination in internal hospital environments as well as external areas surrounding hospitals, both of which encounter high pedestrian traffic in cities worldwide.

关键词： COVID-19 global epidemic Dimensional analysis Wind velocity Hospital environment Contamination

The role of lysyl oxidase-like 1 and fibulin-5 in the development of atherosclerosis and pelvic organ prolapse

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The Journal of Biomedical Research 2013年第3期27卷 242-242页

作者： Fabrizio dal moro Department of Surgical Oncological and Gastroenterological Sciences-UrologyUniversity of Padova

Dear Editor： I would like to congratulate Zhou et al.[1] on their study of the correlation between expression of lysyl oxidase-like 1 （LOX-1） and fibulin-5 （F5） in the car- dinal ligament tissue and pelvic organ prolapse （POP）. In their elegant work, they evaluated the levels of LOX-1 and F5 in connective tissue of the cardinal ligament in order to demonstrate signs of elastinopa- thy in women with POP. They stress the concept that several environmental risk factors could cause qualitative and quantitative changes in the connective tissue promoting POP. The above authors conclude that the specific mechanism of LOXL1 and F5 involved in the development of POP is unclear.

关键词： The role of lysyl oxidase-like 1 and fibulin-5 in the development of atherosclerosis and pelvic organ prolapse

Does Helicobacter pylori infection eradication modify peptic ulcer prevalence? A 10 years' endoscopical survey

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World Journal of Gastroenterology 2006年第15期12卷 2398-2401页

作者： Giorgio Nervi Stefania Liatopoulou Lucas Giovanni Cavallaro Alessandro Gnocchi Nadia dal Bò Massimo Rugge Veronica Iori Giulia Martina Cavestro Marta Maino giancarlo Colla Angelo Franzè Francesco Di Mario Gastroenterology Unit Parma Italy Department of Clinical Sciences Chair of Gastroenterology ParmaItaly Gastroenterology Unit Treviso Italy Institute of Pathology University of Padova Italy

瞄准：为了在病人比较消化性溃疡流行，在根除治疗的进步散开以后在 pre-Helicobacter 时代和十年在二所意大利的医院里为上面的胃肠的内视镜检查法参考了。方法：我们检查了连续地在 1992 和 2002 期间在 1986-1987 和 1995-1996 期间... 详细信息

瞄准：为了在病人比较消化性溃疡流行，在根除治疗的进步散开以后在 pre-Helicobacter 时代和十年在二所意大利的医院里为上面的胃肠的内视镜检查法参考了。方法：我们检查了连续地在 1992 和 2002 期间在 1986-1987 和 1995-1996 期间在 Padova 的肠胃病学单位，并且在 Parma 的肠胃病学单位执行的所有内视镜的考试。迟平方测试被用于统计分析。结果：从两个的数据内视镜的中心在溃疡的流行显示出统计上重要的减少：从 12.7% ～ 6.3%(P<0.001 ) 在 Padova 并且从 15.6% ～ 12%(P<0.001 ) 在 Parma。减少两个都是重要的为十二指肠(从 8.8% ～ 4.8% ， P<0.001 ) 并且胃溃疡(3.9% ～ 1.5% ， P<0.001 ) 在 Padova，并且仅仅为在 Parma 的十二指肠溃疡(9.2% ～ 6.1% ， P<0.001；胃溃疡：6.3% ～ 5.8% ， NS ) 。结论：在征兆的病人的根除在消化性溃疡流行导致了重要减小的广泛的 Helicobacter pylori (H pylori ) 的十年。这减小在 Padova 是特别地明显的，在为在一般 practioners 之中的 H pylori 根除的致敏的一个工程在 1990 和 1992 之间被执行的地方。假如我们的假设应该是真的， H pylori 根除可能在未来导致是的消化性溃疡一稀罕内视镜的发现。

关键词：幽门螺杆菌细菌感染胃溃疡流行病学

Verification of the Validity of the NPT Treatment in Hereditary Spastic Paraplegia: An Investigation Performed by Application of Random Matrix Theory

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World Journal of Neuroscience 2016年第1期6卷 1-17页

作者： Elio Conte Ken Ware Riccardo Marvulli giancarlo Ianieri Marisa Megna School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics Bari Italy Neurotricional Sciences Pty Ltd. Arundel Australia Department of Physical Medicine and Rehabilitation University Aldo Moro Bari Italy

We have applied the Random Matrix Theory in order to examine the validity of the NPT treatment in HSP. We have investigated the pathology examining the sEMG recorded signal for about eight minutes. We have performed standard electromyographic investigations as well as we have applied the RMT method of analysis. We have investigated the sEMG signals before and after the NPT treatment. The application of a so robust method as the RMT evidences that the NPT treatment was able to induce a net improvement of the disease respect to the pathological status before NPT.

关键词： Hereditary Spastic Paraplegia NPT Treatment Random Matrix Theory Surface Electromiography

Heart Rate Variability: On the Importance to Perform HRV Analysis in Subjects Affected from Muscular Dystrophy

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World Journal of Cardiovascular Diseases 2015年第6期5卷 141-149页

作者： Elio Conte Ken Ware Riccardo Marvulli giancarlo Ianieri Marisa Megna Sergio Conte Leonardo Mendolicchio Enrico Pierangeli School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics Bari Italy Department of Basic Sciences Neuroscience and Sense Organs University of Bari Aldo Moro Bari Italy The International Neuro Physics Functional Performance Institute Energy Circuit Robina Australia Department of Physical Medicine and Rehabilitation University of Bari Aldo Moro Bari Italy

This paper discusses a case of muscular dystrophy on which it has been performed HRV analysis. The results that we obtain evidence that the subject delineates a net ANS dysfunction. All the basic parameters relating standard time and frequency domain of HRV analysis result profoundly altered. Examination by Poicaré plot evidences in particular that the subject has an atrial fibrillation. Non linear indexes ApEn and Samp En evidence the very high condition of risk of the subject. The merging indication is for the cardiologist and scholars in cardiovascular disease to perform always ANS investigation in subjects in case of muscular dystrophy. After the NPT treatment, the subject obtains a net improvement.

关键词： ANS Dysfunction in Muscular Dystrophy HRV Analysis Atrial Fibrillation

Chaos, Fractal and Recurrence Quantification Analysis of Surface Electromyography in Muscular Dystrophy

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World Journal of Neuroscience 2015年第4期5卷 205-257页

作者： Elio Conte Ken Ware Riccardo Marvulli giancarlo Ianieri Marisa Megna Sergio Conte Leonardo Mendolicchio Enrico Pierangeli School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics Bari Italy Department of Basic Sciences Neuroscience and Sense Organs University of Bari Aldo Moro Bari Italy The International NeuroPhysics Functional Performance Institute Robina Queensland Australia Department of Physical Medicine and Rehabilitation University of Bari Aldo Moro Bari Italy

We analyze muscular dystrophy recorded by sEMG and use standard methodologies and nonlinear chaotic methods here including the RQA. We reach sufficient evidence that the sEMG signal contains a large chaotic component. We have estimated the correlation dimension (fractal measure), the largest Lyapunov exponent, the LZ complexity and the %Rec and %Det of the RQA demonstrating that such indexes are able to detect the presence of repetitive hidden patterns in sEMG which, in turn, senses the level of MU synchronization within the muscle. The results give also an interesting methodological indication in the sense that it evidences the manner in which nonlinear methods and RQA must be arranged and applied in clinical routine in order to obtain results of clinical interest. We have studied the muscular dystrophy and evidence that the continuous regime of chaotic transitions that we have in muscular mechanisms may benefit in this pathology by the use of the NPT treatment that we have considered in detail in our previous publications.

关键词： Chaos Analysis Correlation Dimension LZ Complexity Recurrence Quantification Analysis Muscular Dystrophy Chaos and Fractal Estimation by Surface Electromyography

Analysis of Brain-Neuromuscular Synchronization and Coupling Strength in Muscular Dystrophy after NPT Treatment

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World Journal of Neuroscience 2015年第4期5卷 302-321页

作者： Elio Conte Ken Ware Riccardo Marvulli giancarlo Ianieri Marisa Megna Sergio Conte Leonardo Mendolicchio Enrico Pierangeli School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics Bari Italy Department of Basic Sciences Neuroscience and Sense Organs University of Bari Aldo Moro Bari Italy Department of Physical Medicine and Rehabilitation University of Bari Aldo Moro Bari Italy The International NeuroPhysics Functional Performance Institute Robina Australia

We perform an analysis of brain-neuromuscular synchronization and coupling strength in muscular dystrophy before and after NPT treatment. In order to estimate with accuracy the level of brain synchronization, we introduce and use the method of the cross GMI that was elaborated by Pompe. The finality is to account for the nonlinear chaotic dynamic contributions that regulate the dynamics. We find that this method is excellent and it may be applied in such case of sEMG and EEG study as well as at a general neurological level. By it we arrive to quantify the coupling strength and synchronization first between two muscular sections (left and right trapezes) and after between Brain activity, as recorded by the EEG, and the trapezes. We compare the results before and after the NPT treatment and we find that the improvement obtained following such treatment is very consistent. We have now in progress other studies relating in particular the application of such new methodologies to other more serious pathologies as the HSP (Hereditary Spastic Paraplegia).

关键词： Chaos Analysis Muscular Dystrophy Brain Synchronization Analysis Generalized Mutual Information Surface Electromyography EEG