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Spatial Morphology Evolution Characteristics Analysis of the Resident Population Distribution in Henan, China

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Journal of Geoscience and Environment Protection 2024年第3期12卷 163-180页

作者： Kaiguang Zhang Hongling Meng Mingting ba Danhuan Wen School of Geography and Tourism Zhengzhou Normal University Zhengzhou China

The population spatial distribution pattern and its evolving pattern play an important role in regional allocation of social resources and production factors, formulation of regional development plans, construction of a better life society, and promotion of regional economic development. based on the resident population statistics data of Henan province from 2006 to 2021, with county as the basic study unit, the paper studies the spatial morphology characteristics and its evolution patterns of resident population distribution, by using spatial analysis methods such as population distribution center, standard deviation ellipse, and spatial auto correlation analysis. The results show that: the resident population spatial distribution shows unbalanced state, the population agglomeration areas mainly distribute in the northeast part and north part, where the resident population growth rate is significantly higher than other regions, over time, this trend is gradually becoming significant. The resident population distribution has a trend of centripetal concentration, with the degree and trend of centripetal gradually strengthening. The resident population distribution has obvious directional characteristics, but the significance is not high, the weighted resident population average center is approximately located at (4.13740˚N, 113.8935˚E), and the azimuth of the distribution axis is approximately 11.19˚. The population distribution has obvious agglomeration characteristics, with the built-up areas of Zhengzhou and Luoyang as their centers, where have a significant siphon effect on the surrounding population. The southern and southwestern regions in the province form a relatively stable belt area of Low-Low agglomeration areas.

关键词： Resident Population Spatial Distribution Spatial Morphology Temporal and Spatial Evolution Center Migration Standard Deviation Ellipse Spatial Autocorrelation

Levels of evidence and grades of recommendation supporting European society for medical oncology clinical practice guidelines

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Oncology Research 2024年第5期32卷 807-815页

作者： MARKO SKELIN BRUNA PERKOV-STIPIČIN SANJA VUŠKOVIĆ MARINAŠANDRK PLEHAČEK ANE baŠIĆ DAVIDŠARČEVIĆ MAJA ILIĆ IVAN KREČAK Pharmacy Department General Hospital ofŠibenik-Knin CountyŠibenikCroatia Faculty of Medicine University of RijekaRijekaCroatia Undergraduate Study in Nursing University of Applied SciencesŠibenikCroatia Department of Oncology University Hospital Center ZagrebZagrebCroatia Pharmacies Joukhadar Sveta NedeljaCroatia Pharmacies Prima Pharme ZagrebCroatia Pharmacy Department General Hospital ZadarZadarCroatia Pharmacy Department General Hospital PulaPulaCroatia Department of Internal Medicine General Hospital ofŠibenik-Knin CountyŠibenikCroatia

background:The European Society for Medical Oncology(ESMO)guidelines are among the most comprehensive and widely used clinical practice guidelines(CPGs)***,the level of scientific evidence supporting ESMO CPG recommendations has not been systematically *** study assessed ESMO CPG levels of evidence(LOE)and grades of recommendations(GOR),as well as their trends over time across various cancer ***:We manually extracted every recommendation with the Infectious Diseases Society of America(IDSA)classification from each *** examined the distribution of LOE and GOR in all available ESMO CPG guidelines across different topics and cancer ***:Among the 1,823 recommendations in the current CPG,30%were classified as LOEⅠ,and 43%were classified as GOR ***,there was a slight decrease in LOEⅠ(−2%)and an increase in the proportion of GOR A(+1%)in the current CPG compared to previous *** proportion of GOR A recommendations based on higher levels of evidence such as randomized trials(LOEⅠ–Ⅱ)shows a decrease(71%vs.63%,p=0.009)while recommendations based on lower levels of evidence(LOEⅢ–Ⅴ)show an increase(29%vs.37%,p=0.01)between previous and current *** the current versions,the highest proportion of LOEⅠ(42%)was found in recommendations related to pharmacotherapy,while the highest proportion of GOR A recommendations was found in the areas of pathology(50%)and diagnostic(50%)*** variability in LOEⅠand GOR A recommendations and their changes over time was observed across different cancer ***:One-third of the current ESMO CPG recommendations are supported by the highest level of *** well-designed randomized clinical trials are needed to increase the proportion of LOEⅠand GOR A recommendations,ultimately leading to improved outcomes for cancer patients.

关键词： ESMO guidelines Clinical practice guidelines Level of evidence Grade of recommendation

Aviation Safety and Data Mining in Marketing Dimension

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Advances in Aerospace Science and Technology 2024年第3期9卷 117-127页

作者： Sevgi Adigüzel Murat başal Emel Saraç Transportation Services Department Idr University Idr Trkiye Vocational School Istanbul Gelisim University Istanbul Trkiye Department of Business Administration Institute of Social Sciences Ostim Technical University Ankara Trkiye

The aviation industry is a sector that is developing, changing and growing every day in terms of technological and legal framework. There are generally three factors that enable airlines to hold on to the market. These factors are safety, service quality and price. Airline companies can analyze the customers in the market with a focus on price and quality and develop a business model according to their expectations. For example, business class and economy class passenger expectations are different from each other, so the service and price to be offered to them will be different. However, all customers have one common expectation and that is safety. No matter how high quality the service is or how cheap the price is, no one wants to fly with an airline or plane that is not safe. From an airline company’s point of view, an accident or breakdown of one of the company’s aircraft can cause irreparable image loss and financial damage. If we look at past examples, we see that there are many airline companies or maintenance organizations that could not recover after an accident and went bankrupt. Safety is an indispensable factor. Therefore, there is a unit in the sector called the safety management system (SMS), which collects data by taking a proactive and reactive approach. The way and purpose of the safety management system is to take a proactive approach to recognize and prevent unsafe situations before they cause accidents or breakdowns, or to take a reactive approach to find the causes of accidents and breakdowns that have occurred as a result of certain factors and to take the necessary measures to prevent the same situations from happening again in the sector. The field of data mining, which is necessary to predict the future behavior of customers in the field of marketing, is an area that marketing also values. In this study, data mining studies to ensure safety in the aviation industry and the security of customer information in marketing will be emphasized, firs

关键词： Data Mining Aviation Customer Safety Marketing

Selective butyric acid production from CO_(2)and its upgrade to butanol in microbial electrosynthesis cells

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Environmental Science and Ecotechnology 2024年第1期17卷 119-127页

作者： Meritxell Romans-Casas Laura Feliu-Paradeda Michele Tedesco Hubertus V.M.Hamelers Lluis bañeras M.Dolors balaguer SebastiàPuig Paolo Dessì Institute of the Environment University of Girona.Campus MontiliviCarrer Maria Aurélia Capmany 69E-17003GironaSpain Molecular Microbial Ecology Group Institute of Aquatic EcologyUniversity of GironaMaria Aurelia Capmany 4017003GironaSpain Wetsus European Centre of Excellence for Sustainable Water TechnologyOostergoweg 98911MALeeuwardenthe Netherlands

Microbial electrosynthesis(MES)is a promising carbon utilization technology,but the low-value products(i.e.,acetate or methane)and the high electric power demand hinder its industrial *** this study,electrically efficient MES cells with a low ohmic resistance of 15.7 mU m^(2)were operated galvanostatically in fed-batch mode,alternating periods of high CO_(2)and H2 *** promoted acetic acid and ethanol production,ultimately triggering selective(78%on a carbon basis)butyric acid production via chain *** average production rate of 14.5 g m^(-2)d^(-1)was obtained at an applied current of 1.0 or 1.5 mA cm^(-2),being Megasphaera *** key chain elongating *** a second cell with the catholyte containing the enriched community resulted in butyric acid production at the same rate as the previous cell,but the lag phase was reduced by 82%.Furthermore,interrupting the CO_(2)feeding and setting a constant pH2 of 1.7e1.8 atm in the cathode compartment triggered solventogenic butanol production at a pH below *** efficient cell design resulted in average cell voltages of 2.6e2.8 V and a remarkably low electric energy requirement of 34.6 kWhel kg1 of butyric acid produced,despite coulombic efficiencies being restricted to 45%due to the cross-over of O_(2)and H2 through the *** conclusion,this study revealed the optimal operating conditions to achieve energy-efficient butyric acid production from CO_(2)and suggested a strategy to further upgrade it to valuable butanol.

关键词： Biocathode Bioelectrochemical system Chain elongation Hydrogen partial pressure Megasphaera

Woody plant taxonomic,functional,and phylogenetic diversity decrease along elevational gradients in Andean tropical montane forests:Environmental filtering and arrival of temperate taxa

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Plant Diversity 2024年第4期46卷 491-501页

作者： Guillermo bañares-de-Dios Manuel J.Macía Gabriel Arellano Íñigo Granzow-de la Cerda Julia Vega-álvarez Itziar Arnelas Carlos I.Espinosa Norma Salinas Luis Cayuela Departamento de Biología y Geología Física y Química InorgánicaUniversidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain Departamento de Biología Área de BotánicaUniversidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridCalle Darwin 2MadridES-28049Spain Ecology and Evolutionary Biology University of MichiganAnn ArborMI 48109USA Oikobit LLC ***AlbuquerqueNM87120USA Real Jardín Botánico–CSIC Plaza Murillo 2MadridES-28014Spain Departamento de Biología Animal EcologíaParasitologíaEdafología y Química AgrícolaUniversidad de SalamancaCalle Donantes de Sangre s/nSalamancaES-37007Spain Departamento de Biodiversidad Ecología y EvoluciónUniversidad Complutense de MadridCalle JoséAntonio Nováis 12Ciudad UniversitariaES-28040Spain Departamento de Ciencias Biológicas y Agropecuarias Universidad Técnica Particular de LojaA.P.11-01-608 LojaEcuador Sección Química Pontificia Universidad Católica del PerúA.P.Lima 32LimaPeru ECI School of Geography and EnvironmentUniversity of OxfordOX13QYOxfordshireUnited Kingdom Instituto de Investigación en Cambio Global(IICG-URJC) Universidad Rey Juan CarlosCalle Tulipán s/nMóstolesMadridES-28933Spain

Mountains are paramount for exploring biodiversity patterns due to the mosaic of topographies and climates encompassed over short *** research has traditionally focused on taxonomic diversity when investigating changes along elevational gradients,but other facets should be *** first time,we simultaneously assessed elevational trends in taxonomic,functional,and phylogenetic diversity of woody plants in Andean tropical montane forests and explored their underlying ecological and evolutionary *** investigation covered four transects(traversing ca.2200 m a.s.l.) encompassing 114 plots of 0.1 ha across a broad latitudinal range(ca.10°).Using Hill numbers to quantify abundance-based diversity among 37,869 individuals we observed a consistent decrease in taxonomic,functional,and phylogenetic diversity as elevation increased,although the decrease was less pronounced for higher Hill *** exception was a slight increase in phylogenetic diversity when dominant species were *** decrease in taxonomic and functional diversity might be attributed to an environmental filtering process towards highlands,where the increasingly harsher conditions exclude species and functional ***,the differences in steepness decrease between Hill orders suggest that rare species disproportionately contribute to functional *** phylogenetic diversity the shifting elevational trend between Hill orders indicates a greater than previously considered influence in central Andean highlands of tropical lowlands originated species with strong niche conservatism relative to distantly related temperate *** could be explained by a decreasing presence and abundance of temperate,extratropical taxa towards the central Andes relative to northern or southern Andes,where they are more prevalent.

关键词： Altitudinal gradients Andes Environmentalﬁltering Out of the Tropical Lowlands Functional rarity Tropical Niche Conservatism

Nutritional Characterization of Traditional Foods based on Millet, Sorghum and Cowpea from the North-Central Region of Burkina Faso

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Food and Nutrition Sciences 2024年第8期15卷 681-694页

作者： Rasmata Dabo Fatoumata Hama.ba.Serge Samandoulgou Aly Savadogo Food Technology Department Institute for Research in Applied Sciences and Technologies National Center for Scientific and Technological Research Ouagadougou Burkina Faso Laboratory of Biochemistry and Applied Immunology Training and Research Unit in Life and Earth Sciences Joseph Ki-Zerbo University Ouagadougou Burkina Faso

The food and nutrition situation in Burkina Faso, like most developing countries in sub-Saharan Africa, is marked by growing food vulnerability. The majority of local dishes are being abandoned in favor of a minority of imported cereal dishes and other ultra-processed foods. This minority of cereal foods is blamed for stunted growth in children, while ultra-processed foods are linked to chronic diseases such as hypertension, certain types of diabetes and cancer. Knowledge of the nutritional value of local foods is needed to determine their nutritional quality. The aim of this study was to determine the nutritional values of local dishes based on millet, sorghum and cowpea in the Centre-North region. The methodology consisted of making an inventory of millet-, sorghum- and cowpea.ba.ed dishes using focus groups made up of women and men from three age groups comprising young people, adults and the elderly in the communes of Lebda and Boussouma. The dishes were reproduced, and standard biochemical methods were used for nutritional characterization. A total of 34 dishes were inventoried, including 16 millet/sorghum-based dishes, 8 cowpea.ba.ed dishes and 10 dishes composed of millet/sorghum and cowpea or leaves. The mean protein, carbohydrate, ash and iron contents per 100 g DM of the three types of dishes were significantly different (p ≤ 0.05), ranging respectively from 13.61 to 22.63 g, 70.76 to 80.88 g, 1.87 to 5.96 g and 7.67 to 12.06 mg. Those for lipid, energy and zinc were not significantly different, ranging from 5.51 to 6.56 g, from 427 to 433 Kcal and from 2.98 to 3.32 mg respectively. Cowpea.ba.ed and mixed dishes cover the nutritional requirements for protein, carbohydrates, iron, zinc and energy recommended for children and adults. The consumption of mixed dishes and cowpea.ba.ed dishes could be promoted by nutritional policy to reduce stunting and recommended to obese, hypertensive and diabetic people as part of their diet.

关键词： Cereals Legumes Food Nutritional Burkina Faso

Synaptotagmins family affect glucose transport in retinal pigment epithelial cells through their ubiquitination-mediated degradation and glucose transporter-1 regulation

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World Journal of Diabetes 2024年第5期15卷 958-976页

作者： Hong Xu Li-Bo Zhang Yi-Yi Luo Ling Wang Ye-Pin Zhang Pei-Qi Chen Xue-Ying ba Jian Han Heng Luo Department of Ophthalmology The People’s Hospital of Chuxiong Yi Autonomous Prefecture&The Fourth Affiliated Hospital of Dali UniversityChuxiong Yi Autonomous Prefecture 675000Yunnan ProvinceChina Precision Medicine Center of Chuxiong Yi Autonomous Prefecture The People’s Hospital of Chuxiong Yi Autonomous Prefecture&The Fourth Affiliated Hospital of Dali UniversityChuxiong Yi Autonomous Prefecture 675000Yunnan ProvinceChina Department of Endocrinology The People’s Hospital of Chuxiong Yi Autonomous Prefecture&The Fourth Affiliated Hospital of Dali UniversityChuxiong Yi Autonomous Prefecture 675000Yunnan ProvinceChina Department of Pathology The People’s Hospital of Chuxiong Yi Autonomous Prefecture&The Fourth Affiliated Hospital of Dali UniversityChuxiong Yi Autonomous Prefecture 675000Yunnan ProvinceChina

baCKGROUND Synaptotagmins(SYTs)are a family of 17 membrane transporters that function as calcium ion sensors during the release of Ca2+-dependent neurotransmitters and ***,few studies have reported whether members of the SYT family play a role in glucose uptake in diabetic retinopathy(DR)through Ca2+/glucose transporter-1(GLUT1)and the possible regulatory mechanism of *** To elucidate the role of the SYT family in the regulation of glucose transport in retinal pigment epithelial cells and explore its potential as a therapeutic target for the clinical management of *** DR was induced by streptozotocin in C57BL/6J mice and by high glucose medium in human retinal pigment epithelial cells(ARPE-19).Bioinformatics analysis,reverse transcriptase-polymerase chain reaction,Western blot,flow cytometry,ELISA,HE staining,and TUNEL staining were used for *** Six differentially expressed proteins(SYT2,SYT3,SYT4,SYT7,SYT11,and SYT13)were found between the DR and control groups,and SYT4 was highly *** induces SYT4 overexpression,manipulates Ca2+influx to induce GLUT1 fusion with the plasma membrane,promotes abnormal expression of the glucose transporter GLUT1 and excessive glucose uptake,induces ARPE-19 cell apoptosis,and promotes DR *** deficiency inhibits the proteasomal degradation of SYT4 in DR,resulting in SYT4 accumulation and enhanced GLUT1 fusion with the plasma membrane,and these effects were blocked by oe-Parkin ***,dysregulation of the myelin transcription factor 1(Myt1)-induced transcription of SYT4 in DR further activated the SYT4-mediated stimulus-secretion coupling process,and this process was inhibited in the oe-MYT1-treated *** Our study reveals the key role of SYT4 in regulating glucose transport in retinal pigment epithelial cells during the pathogenesis of DR and the underlying mechanism and suggests potential therapeutic targets for clinical DR.

关键词： Diabetic retinopathy Glucose transporter-1 Synaptotagmin 4 Parkin Myelin transcription factor 1

中国特色历史学“三大体系”建设的内生动力与外部推力

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史学理论研究 2024年第2期 34-43页

作者：把增强河北大学历史学院河北省社会科学院

构建中国特色哲学社会科学“三大体系”是2016年5月17日习近平总书记在哲学社会科学工作座谈会上发表的重要讲话(以下简称“5·17”重要讲话)中正式提出的。这里所称的“三大体系”,系学科体系、学术体系、话语体系的简称。“5·17”重... 详细信息

构建中国特色哲学社会科学“三大体系”是2016年5月17日习近平总书记在哲学社会科学工作座谈会上发表的重要讲话(以下简称“5·17”重要讲话)中正式提出的。这里所称的“三大体系”,系学科体系、学术体系、话语体系的简称。“5·17”重要讲话发表后,学术界和理论界围绕如何开展好中国特色哲学社会科学“三大体系”建设进行了积极探索。作为中国特色哲学社会科学的重要组成部分,中国特色历史学“三大体系”建设也随之提上重要日程。这里面还有一个重要契机,即2019年1月3日中国社会科学院中国历史研究院的成立,尤其是习近平总书记致中国社会科学院中国历史研究院成立的贺信,既向广大史学工作者提出了殷切期望,也直接加快了中国特色历史学“三大体系”建设的步伐。

关键词：中国社会科学院中国特色哲学社会科学史学工作者内生动力学术体系哲学社会科学工作座谈会外部推力三大体系

铸牢中华民族共同体意识教育常态化的法治保障——基于《爱国主义教育法》的思考

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中南民族大学学报（人文社会科学版） 2024年第7期44卷 69-74,183页

作者：巴玉玺中南民族大学大学生思想政治教育研究中心湖北武汉430074

《爱国主义教育法》的颁布实施,以国家法规的强制力为铸牢中华民族共同体意识教育提供了更为完善的法规保障。通过从法律上确立铸牢中华民族共同体意识教育的地位和任务,促进铸牢中华民族共同体意识教育体系的不断完善,汇聚起铸牢中华... 详细信息

《爱国主义教育法》的颁布实施,以国家法规的强制力为铸牢中华民族共同体意识教育提供了更为完善的法规保障。通过从法律上确立铸牢中华民族共同体意识教育的地位和任务,促进铸牢中华民族共同体意识教育体系的不断完善,汇聚起铸牢中华民族共同体意识教育的社会合力,并以法规的形式进一步明确了学校始终是铸牢中华民族共同体意识教育的主阵地,有力地推进铸牢中华民族共同体意识教育的常态化开展。

关键词：爱国主义教育法法治保障铸牢中华民族共同体意识教育常态化大思政体系