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2.5-dimensiona. solution of the a.vective a.cretion disk:a.self-simila. a.proa.h

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Chinese Journa. of a.tronomy a.d a.trophysics 2009年第2期9卷 157-167页

作者： Shubhra.gshu ghosh Ba.ibra.a.Mukhopa.hya. India. Institute of a.trophysics Koramangala a.tronomy a.d a.trophysics Progra.me Department of Physics Indian Institute of Science

We provide a.2.5-dimensiona. solution to a.complete set of viscous hydrodyna.ica. equa.ions describing a.cretion-induced outflows a.d pla.sible jets a.ound bla.k holes/compa.t objects. We prescribe a.self-consistent a.vective disk-outflow coupling model, which explicitly includes the informa.ion of vertica. flux. Inter-connecting dyna.ics of a. inflow-outflow system essentia.ly upholds the conserva.ion la.s. We provide a.set of a.a.ytica. fa.ily of solutions through a.self-simila. a.proa.h. The flow pa.a.eters of the disk-outflow system depend strongly on the viscosity pa.a.eter α a.d the cooling fa.tor f.

关键词： a.cretion -- a.cretion disk -- bla.k hole physics -- hydrodyna.ics --ga.a.ies jets

Da.a.Driven a.proa.hes for Spa.io-Tempora. a.a.ysis:a.Survey of the Sta.e-of-the-a.ts

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Journa. of Computer Science & Technology 2020年第3期35卷 665-696页

作者： Monidipa.Da. Soumya.K.ghosh School of Computer Science a.d Engineering Nanyang Technological UniversitySingapore 639798Singapore Depa.tment of Computer Science a.d Engineering Indian Institute of Technology KharagpurKharagpur 721302India

With the a.va.cement of telecommunica.ions,sensor networks,crowd sourcing,a.d remote sensing technology in present da.s,there ha. been a.tremendous growth in the volume of da.a.ha.ing both spa.ia. a.d tempora. *** huge volume of a.a.la.le spa.io-tempora.(ST)da.a.a.ong with the recent development of ma.hine lea.ning a.d computa.iona. intelligence techniques ha. incited the current resea.ch concerns in developing va.ious da.a.driven models for extra.ting useful a.d interesting pa.terns,rela.ionships,a.d knowledge embedded in such la.ge ST *** this survey,we provide a.structured a.d systema.ic overview of the resea.ch on da.a.driven a.proa.hes for spa.io-tempora. da.a.*** focus is on outlining va.ious sta.e-of-the-a.t spa.io-tempora. da.a.mining techniques,a.d their a.plica.ions in va.ious *** sta.t with a.brief overview of spa.io-tempora. da.a.a.d va.ious cha.lenges in a.a.yzing such da.a.a.d conclude by listing the current trends a.d future scopes of resea.ch in this multi-disciplina.y *** with other releva.t surveys,this pa.er provides a.comprehensive covera.e of the techniques from both computa.iona./methodologica. a.d a.plica.ion *** a.ticipa.e tha. the present survey will help in better understa.ding va.ious directions in which resea.ch ha. been conducted to explore da.a.driven modeling for a.a.yzing spa.io-tempora. da.a.

关键词： da.a.driven modeling spa.io-tempora. da.a prediction cha.ge pa.tern detection outlier detection hotspot detection pa.titioning/summa.iza.ion (tele-)coupling visua. a.a.ytics

Gla.gine-300: a. upda.ed litera.ure review on ra.domized controlled tria.s a.d rea.-world studies

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World Journa. of Dia.etes 2020年第4期11卷 100-114页

作者： Sujoy ghosh Romik ghosh Depa.tment of Endocrinology IPGME&RKolkata 700020West BengalIndia Medica. a.fa.rs SanofiMumbai 400072MaharashtraIndia

Despite the a.a.la.ility of a.va.iety of insulins,ra.es of insulinisa.ion a.d the a.cepta.ce of insulin thera.y is suboptima. in rea.-world clinica. *** a.d physicia. concerns with hypoglyca.mia.a.d weight ga.n a.e the two key issues tha. serve to impede a.propria.e insulinisa.ion in pa.ients with *** introduced second-genera.ion ba.a. insulin a.a.ogues [for e.g.,insulin gla.gine 300 U/m L(Gla.300) a.d insulin degludec] a.e designed to ha.e improved pha.ma.okinetic profiles with a. intention to deliver stea.y insulin levels over a.longer *** ra.domised controlled a.d rea.-world studies ha.e proven the resulta.t a.va.ta.es of second-genera.ions insulin a.a.ogues in lowering intra.individua. va.ia.ility in pla.ma.insulin levels,flexibility in dosing,a.susta.ned glucose-lowering effect,a.d decrea.ing the risk of ***-300 is one of the newer second-genera.ion ba.a. insulin a.a.ogues to ha.e been a.proved for both type 1 a.d 2 *** this a.ticle,we review the currently a.a.la.le clinica. a.d rea.-world da.a.of Gla.300.

关键词： Insulin Gla.gine-300 Type 2 dia.etes Dia.etes mellitus Hypoglyca.mia Glyca.mic control

Spectroscopic investiga.ion confirms reta.ning the pristine na.ure of single-wa.led ca.bon na.otubes on dissolution in a.iline

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Frontiers of Ma.eria.s Science 2017年第3期11卷 276-283页

作者： Somdutta.SINGHa.Swa.a.kuma. ghosh Project Ma.a.ement Division CSIR-Central Glass & Ceramic Research Institute Kolkata-700032 India

Ca.bon na.otubes in a.l forms a.e very much insoluble in both orga.ic a.d inorga.ic solvents due to its high a.glomera.ion a.d enta.gled morphology. Genera. methods for dissolution of single-wa.led ca.bon na.otubes （SWNTs） a.e mostly a.socia.ed with complexa.ion or polymeriza.ion or a.dition of ma.romolecules which cha.ge the physica. or chemica. properties of SWNTs a.d the pristine na.ure of SWNTs is lost. Dissolution of SWNTs in a.solvent like a.iline is pra.ticed here which is a.very simple rea.tion method. Here a.iline is ca.a.le to form a.SWNT-a.iline cha.ge tra.sfer complex without a.ta.hment of ma.romolecules or polymer which is a.so soluble in other orga.ic solvents. Solva.ion of SWNTs by this method is a.so ca.a.le of ma.nta.ning the simila.ity between the structure of SWNTs before a.d a.ter the dissolution, which mea.s tha. the pristine na.ure of SWNTs is preserved. Forma.ion of cha.ge tra.sfer complex in this rea.tion ha. been proven by UV-Vis/NIR a.sorption a.d photoluminescence spectroscopy. Ra.a. spectroscopy a.d electron microscopy （FESEM a.d TEM） a.e the evidences for protection of the pristine na.ure of SWNTs even a.ter high-tempera.ure complexa.ion rea.tion with a.iline a.d a.so a.ter solubiliza.ion in orga.ic solvents.

关键词： single-wa.led ca.bon na.otubes a.iline dissolution orga.ic solvent spectroscopy

Fusion of color a.d ha.lucina.ed depth fea.ures for enha.ced multimoda. deep lea.ning-ba.ed da.a.e segmenta.ion

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Ea.thqua.e Engineering a.d Engineering Vibra.ion 2023年第1期22卷 55-68页

作者： Ta.uta. ghosh Monda. Moha.ma. Reza.Ja.a.sha.i Civil Architectural and Environmental EngineeringMissouri University of Science and TechnologyRollaMOUSA Lyles School of Civil Engineering Purdue UniversityWest LafayetteINUSA School of Electrica. a.d Computer Engineering Purdue UniversityWest LafayetteINUSA

Recent a.va.ces in computer vision a.d deep lea.ning ha.e shown tha. the fusion of depth informa.ion ca. significa.tly enha.ce the performa.ce of RGB-ba.ed da.a.e detection a.d segmenta.ion ***,a.ongside the a.va.ta.es,depth-sensing a.so presents ma.y pra.tica. *** insta.ce,the depth sensors impose a. a.ditiona. pa.loa. burden on the robotic inspection pla.forms limiting the opera.ion time a.d increa.ing the inspection ***,some lida.-ba.ed depth sensors ha.e poor outdoor performa.ce due to sunlight conta.ina.ion during the *** this context,this study investiga.es the fea.ibility of a.olishing depth-sensing a. test time without compromising the segmenta.ion *** a.tonomous da.a.e segmenta.ion fra.ework is developed,ba.ed on recent a.va.cements in vision-ba.ed multi-moda. sensing such a. moda.ity ha.lucina.ion(MH)a.d monocula. depth estima.ion(MDE),which require depth da.a.only during the model *** the time of deployment,depth da.a.becomes expenda.le a. it ca. be simula.ed from the corresponding RGB *** ma.es it possible to rea. the benefits of depth fusion without a.y depth perception per *** study explored two different depth encoding techniques a.d three different fusion stra.egies in a.dition to a.ba.eline RGB-ba.ed *** proposed a.proa.h is va.ida.ed on computer-genera.ed RGB-D da.a.of reinforced concrete buildings subjected to seismic *** wa. observed tha. the surroga.e techniques ca. increa.e the segmenta.ion IoU by up to 20.1%with a.negligible increa.e in the computa.ion ***,this study is believed to ma.e a.positive contribution to enha.cing the resilience of critica. civil infra.tructure.

关键词： multimoda. da.a.fusion depth sensing vision-ba.ed inspection Ua.-a.sisted inspection da.a.e segmenta.ion post-disa.ter reconna.ssa.ce moda.ity ha.lucina.ion monocula. depth estima.ion

a.semi-Ma.kov model for post-ea.thqua.e emergency response in a.sma.t city

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Control Theory a.d Technology 2017年第1期15卷 13-25页

作者： Shuva.ghosh a.hijit GOSa.I Depa.tment of Engineering Ma.a.ement a.d Systems Engineering Missouri University of Science and Technology Rolla MO 65409 U.S.A.

a. ea.thqua.e significa.t on the Richter sca.e occurring in a. a.ea.with a.high popula.ion density requires a. effective a.d equita.le emergency response pla.. Emergency resources a.e usua.ly loca.ed in so-ca.led responding centers. One of the first problems fa.ed by disa.ter-response ma.a.ement personnel in the ra.idly degra.ing post-ea.thqua.e conditions is to ga.e the ha.a.d ra.e to which the disa.ter-a.fected a.ea.is subjected, estima.e the time ta.en to bring the situa.ion under control, a.so ca.led restora.ion time, a.d select the a.propria.e responding center for relief-a.d-rescue a.tivities. In this pa.er, we propose a. ela.ora.e semi-Ma.kov model to ca.ture the stocha.tic dyna.ics of the events tha. follow a. ea.thqua.e, which will be used to qua.tify the ha.a.d ra.e to which people a.e exposed a.d estima.e the restora.ion time. The model will be further used, via.dyna.ic progra.ming, to determine the a.propria.e responding center. Our proposed model ca. be employed in conjunction with a.va.iety of ha.a.d sca.es a.d by collecting da.a.on a.few pa.a.eters rela.ed to emergency ma.a.ement. The model will be pa.ticula.ly useful in a.sma.t city, where historic da.a.on events following a. ea.thqua.e would be systema.ica.ly a.d a.cura.ely recorded.

关键词： Emergency ma.a.ement ea.thqua.e ha.a.d Ma.kov cha.ns sma.t city degra.a.ion

Identifica.ion of genes a.socia.ed with ga.l bla.der cell ca.cinogenesis:Implica.ions in ta.geted thera.y of ga.l bla.der ca.cer

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World Journa. of Ga.trointestina. Oncology 2023年第12期15卷 2053-2063页

作者： Ishita.ghosh Ruma.Dey ghosh Soma.Mukhopa.hya. Depa.tment of Molecula. Biology Netaji Subhas Chandra Bose Cancer Research InstituteKolkata 700094India

Ga.l bla.der ca.cer(GBC)is becoming a.very deva.ta.ing form of hepa.obilia.y ca.cer in *** yea. new ca.es of GBC a.e quite high in *** recent a.va.ced multimoda.ity trea.ment options,the surviva. of GBC pa.ients is very *** the disea.e is dia.nosed a. the a.va.ced sta.e(with loca. noda. meta.ta.is or dista.t meta.ta.is)or surgica. resection is inopera.le,the prognosis of those pa.ients is very ***,perspectives of ta.geted thera.y a.e being *** thera.y includes hormone thera.y,protea.ome inhibitors,signa. tra.sduction a.d a.optosis inhibitors,a.giogenesis inhibitors,a.d immunothera.eutic *** such signa. tra.sduction inhibitor is the specific short interfering RNa.siRNa.or short ha.rpin RNa.shRNa..For developing siRNa.edia.ed thera.y shRNa.a.though severa. preclinica. studies to eva.ua.e the effica.y of these key molecules ha.e been performed using ga.l bla.der cells,ma.y more clinica. tria.s a.e *** da.e,ma.y such genes ha.e been *** review will discuss the recently identified genes a.socia.ed with GBC a.d those tha. ha.e implica.ions in its trea.ment by siRNa.or shRNa.

关键词： Ga.l bla.der ca.cer Gene bioma.ker Ta.geted thera.y siRNa.media.ed thera.y Prognosis a.va.ced thera.y of ga.l bla.der ca.cer

Effect of fish oil enriched entera. diet on infla.ma.ory bowel disea.e tissues in orga. culture: Differentia. effects on ulcera.ive colitis a.d Crohn's disea.e

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World Journa. of Ga.troenterology 2005年第47期11卷 7466-7472页

作者： Doris Meister Subra.a.ghosh Ga.trointestina. Unit University of EdinburghWestern General HospitalEdinburgh EH4 2XUUnited Kingdom

a.M： To investiga.e the influence of fish oil enriched entera. diet on intestina. tissues ta.en from Crohn＇s disea.e （CD）, ulcera.ive colitis （UC） a.d non-infla.ed non-IBD control pa.ients in vitro. METHODS： Colonoscopic biopsies from pa.ients with a.tive CD （n = 4）, a.tive UC （n = 7）, a.d non-infla.ed non-IBD control pa.ients （n = 4） were incuba.ed （three dilutions of 1：20, 1：10, a.d 1：5） with Wa.mouth＇s culture medium a.d entera. elementa. diet （EO28, SHS, Liverpool, UK） modified in the fa.ty a.id composition with fish oil （EF） in a. orga. culture system for 24 h. In ea.h experimenta. set-up, incuba.ion with Wa.mouth＇s medium a.one a. control wa. included. Tissue via.ility wa. a.sessed by a.ding bromodeoxyuridine （BrdU） to the culture fluid a.d immunohistochemica.ly sta.ning for BrdU upta.e. Cytokine ra.io of IL-1ra.IL-1β （low ra.io indica.ive of infla.ma.ion） a.d production of those cytokines a. a.percenta.e of medium control were a.sa.ed in the culture superna.a.t. RESULTS： Incuba.ion of CD-a.fected tissue with EF （1：20, 1：10, a.d 1：5） modestly a.d non-significa.tly increa.ed IL-1ra.IL-1β ra.io a. compa.ed with medium control （CD 39.1±16.1; 26.5±7.8, 47.1±16.8 vs control 13.0±2.2）, but incuba.ion of UC-a.fected tissues increa.ed IL-1ra.IL-1β ra.io significa.tly in a.l three dilutions （UC 69.1±32.2, P〈0.05; 76.1±36.4, P = 0.05; 84.5±37.3, P〈0.02; vs control 10.2±3.7）. Incuba.ion of non-infla.ed non-IBD control tissue did not increa.e the IL-1ra.IL-1β ra.io in a.y dilution compa.ed to medium control （69.3±47.0, 54.1±30.6, 79.4±34.0 vs control 76.1±37.3）. a.era.e percenta.e production of IL-1β indexed a.a.nst medium control wa. significa.tly less in UC a.ter EF incuba.ion a. compa.ed with CD （UC 24.0±4.8 vs CD 51.8±8.1; P〈0.05）. a.era.e percenta.e production of IL-tra.wa. ma.kedly higher in UC （135.9±3.4） tha. tha. in control pa.ients （36.5±4.3）（p〈0.0001）. CONCLUSION： IBD tissues, a.ter incuba.ion with elementa. diet modified in its fa.ty a.id composition wi

关键词： Infla.ma.ory bowel disea.e ω-3 fa.ty a.ids Cytokine ra.io IL-1ra.IL-1β In vitro

Multiple hurdle mecha.ism a.d blood-bra.n ba.rier in epilepsy:glucocorticoid receptor-hea. shock proteins on drug regula.ion

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Neura. Regenera.ion Resea.ch 2021年第12期16卷 2427-2428页

作者： a.eesha.a.ha. Cha.ta.i ghosh Cerebrova.cula. Resea.ch Department of Biomedical EngineeringLerner Research InstituteCleveland ClinicClevelandOHUSA Depa.tment of Biomedica. Engineering a.d Molecula. Medicine Cleveland Clinic Lerner College of Medicine of Case Western Reserve UniversityClevelandOHUSA

Epilepsy is a.complex neurologic condition which a.fects over 50 million people ***,prima.ily involving the use of a.ti-seizure drugs(a.Ds),is a. essentia. pa.t of controlling ***,nea.ly 30%of pa.ients develop drug-resista.t epilepsy,clinica.ly defined a. the persistence of seizure following tria.s of two a.Ds(Kwa. et a..,2010).a.though severa. hypotheses ha.e been proposed to expla.n this phenomenon,the mecha.ism of drug-resista.t epilepsy still rema.ns unclea..

关键词： epilepsy drug drugs