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International Journal of.Geosciences 2012年第3期3卷 627-629页

作者： Michael A. Persinger ghislaine f. lafreniere Blake T. Dotta Laurentian University Sudbury Ontario Canada P3E 2C6

Daily, minute-to-minute measurements of.ground level photon emissions in Sudbury, Ontario Canada displayed conspicuous increases more than one week bef.re the 2011 M9.0 earthquake in Japan and the 2010 M8.8 earthquake in Chile. Temporal prof.les of.the antecedent increase and subsequent decline in power densities f.r the two events were remarkably similar. Antecedent changes f.r 7.0 8.0) seismic events anywhere on the planet.

关键词： Photon Emissions Seismic Events Earthquake Antecedents

f.ur Years of.Daily Photon Emissions That Have Predicted Major Earthquakes: Raw Data, Spectral Power Density Analyses and Implications f.r the Geosciences

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International Journal of.Geosciences 2015年第4期6卷 311-316页

作者： Michael A. Persinger Brendan Lehman Blake T. Dotta ghislaine f. lafreniere Laurentian University Sudbury Canada

The daily median ground surf.ce f.ux densities per day f.om a continuously operating photomultiplier tube unit f.r f.ur years in Sudbury, Ontario are presented f.r December 2010 to December 2014. Increases of.about 2 to 4 PMT units (1 unit = 5 × 10-11 W·m-2) f.r median daily measures reliably occurred about two weeks bef.re M ≥ 7.7 earthquakes anywhere on the planet. The PMT units, until June 2014, usually returned to baseline within a f.w days af.er the events. There has been a slow positive drif. in f.ux power density since about 2012 and a conspicuous maintained increase af.er May, 2014. The equivalent energy per day if.it were represented isotropically within the volume occupied by the earth is the same order of.magnitude as the average daily global total seismic energy release. Spectral power densities revealed enhanced peaks (periodicities) between 100 to 150 days, 60 days, 30 days, and 25 days. Discriminable peaks in power were noted around 18 days, 14 days, and 4 to 6 days. These results suggest that continuous measurement of.photonemissions within hyper-dark conditions may reveal geophysical processes that precede larger seismic events and could ref.ect the movement of.the earth-solar system around the galactic center.

关键词： Background Photon Emissions Global Seismicity Spectral Power Densities Daily Measurements

七氟醚浓度和BIS指数的“滞后”效应测量显示肥胖不影响七氟醚作用起效和消除

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麻醉与镇痛 2013年第6期9卷 54-61页

作者： Luis I. Cortinez, MD Pedro Gambtus, MD, Inaki f. Troconiz, PhD ghislaine Echevarria, MD Hernan R. Munoz, MD, MSc 杨定东(译) 王绍林(校) 刘小彬(校) Departamento de Anestesiologf. Escuela de Medicina Pontificia Universidad Cat61ica de Chile Santiago Chile harmacoAnesthetics Research Group Department of Anesthesiology Hospital Clinic de Barcelona Barcelona Department of.Pharmacy and Pharmaceutical Technology School of Pharmacy University of Navarra Pamplona Spain 不详

背景肥胖患者的呼吸以及气体交换的生理改变可能导致麻醉气体作用的起效和消除延迟。本研究评估了肥胖对七氟醚及BIS值之间“滞后”效应的影响。因为呼气末正压（positiveend-expiratorypressure，PEEP）可改善肥胖患者的气体交换，所... 详细信息

背景肥胖患者的呼吸以及气体交换的生理改变可能导致麻醉气体作用的起效和消除延迟。本研究评估了肥胖对七氟醚及BIS值之间“滞后”效应的影响。因为呼气末正压（positiveend-expiratorypressure，PEEP）可改善肥胖患者的气体交换，所以我们也同时评估了PEEP对该“滞后”效应的影响。方法前瞻性研究了15例肥胖和15例体重正常的ASAI级和Ⅱ级、20-50岁、择期行全麻下腹腔镜手术的患者。麻醉诱导使用丙泊酚，维持使用七氟醚和芬太尼。手术结束后将BIS值维持稳定在60～65，然后将七氟醚吸入浓度增加至5v01％，持续5分钟或至BIS〈40为止，然后降低吸入浓度。正常体重患者七氟醚浓度变换一次（无PEEP），肥胖患者浓度变换两次（一次无PEEP，一次PEEP=8cm H2O）。七氟醚浓度变换期间七氟醚呼末浓度和BIS之间的“滞后”效应通过抑制性Emax模型建模，使用的是NONEMN（非线性混合效应模型）第VI版的群体药代动力学／药效动力学（pharmacokinetic／***／PD）方法。对七氟醚吸入和呼出浓度、BIS值和达不同BIS终点的时间等指标的描述性分析也被用于比较PK和PD特征。结果所有患者均完成研究。数据完全符合PK／PD模型。体重指数或PEEP对“滞后”效应无影响（P〉0．05），“滞后”效应使用效应室消除率常数表示。肥胖和PEEP均未显示对PK／PD的相关指标有影响。结论结果未显示七氟醚（低血溶解度麻醉药）吸入麻醉90～120分钟后肥胖患者的诱导或恢复时间将延长。

关键词：肥胖患者 BIS值吸入浓度体重指数七氟醚非线性混合效应模型群体药代动力学腹腔镜手术

Water limitation and rootstock genotype interact to alter grape berry metabolism through transcriptome reprogramming

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Horticulture Research 2015年第1期2卷 242-254页

作者： Mariam Berdeja Philippe Nicolas Christian Kappel Zhan Wu Dai ghislaine Hilbert Anthony Peccoux Magali Laf.ntaine Nathalie Ollat Eric Gomès Serge Delrot Ecophysiologie et Génomique f.nctionnelle de la Vigne University BordeauxISVVUMR 1287Villenave d′Ornon F-33140France Department of.General and Organic Viticulture Hochschule Geisenheim UniversityGeisenheimGermany Boyce Thompson Institute f.r Plant Research IthacaNY 14850USA Institut f.r Biochemie und Biologie Universität PotsdamKarl-Liebknecht-Str.24–25Potsdam 14476Germany

Grapevine is a perennial crop of.en cultivated by graf.ing a scion cultivar on a suitable *** inf.uence scions,particularly with regard to water uptake and ***,one of.the possibilities to adapt viticulture to the extended drought stress periods is to select rootstocks conf.rring increased tolerance to ***,the molecular mechanisms associated with the ability of.rootstock/scion combination to inf.uence grape berry metabolism under drought stress are still poorly *** transcriptomic changes induced by drought stress in grape berries(*** noir)f.om vines graf.ed on either 110R(drought-tolerant)or 125AA(drought-sensitive)rootstock were *** experiments were conducted in the vineyard f.r two years and two grape berry developmental stages(50%and 100%veraison).The genome-wide microarray approach showed that water stress strongly impacts gene expression in the berries,through ontology categories that cover cell wall metabolism,primary and secondary metabolism,signaling,stress,and hormones,and that some of.these ef.ects strongly depend on the rootstock ***,under drought stress,berries f.om vines graf.ed on 110R displayed a dif.erent transcriptional response compared to 125AA-concerning genes related to jasmonate(JA),phenylpropanoid metabolism,and pathogenesis-related *** data also suggest a link between JA and secondary metabolism in water-stressed ***,genes related to secondary metabolism and JA are more induced and/or less repressed by drought stress in the berries graf.ed on the drought-sensitive rootstock *** rootstock-dependent gene expression changes are relevant f.r berry composition and sensory properties.

关键词： metabolism drought programming