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Galen’s place in Avicenna’s The Canon of Medicine: Respect,confirmation and criticism

Journal of Integrative Medicine 2020年第1期18卷 21-25页

作者： Sajjad Sadeghi Farzaneh Ghaffari ghazaleh heydarirad Mehdi Alizadeh Department of Traditional Medicine School of Traditional MedicineShahid Beheshti University of Medical SciencesTehran ***Iran

Galen(129–199 A.D.), an ancient Greek scholar, is one of the most influential and recognized physicians and surgeons in the history of medicine. He is one of the most influential Greek scholar in Persian medicine, who has been repeatedly cited by Iranian scholars. The purpose of this article is to describe the exact position of Galen in Avicenna’s The Canon of Medicine, the most important work of Persian medicine. In The Canon of Medicine, Galen is cited about 300 times, and Avicenna always admired and praised Galen repeatedly. Galen’s ideas were important to Avicenna, but there are also many elements of Galen’s views that Avicenna challenged or criticized. For example, Avicenna diverged from Galen’s philosophical view in medicine and rejected some of Galen’s pharmaceutical opinions and Galen’s views on the physiology of pain, the physiology of pulse, the same nature of the tendons and nerves and separation of the mind and body. Although the views of Greek scholars, especially Galen, in The Canon of Medicine have been quoted abundantly, Avicenna revised the knowledge of the ancient scholars through critical thinking and relying on observation and testing, systematized the science of medicine and introduced many ideas and innovations. As such, Europeans considered Avicenna as the most prominent physician of the Islamic Golden Age.

关键词： Galen Avicenna The Canon of Medicine Persian medicine

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Efficacy of a traditional Persian medicine preparation for radiation-induced xerostomia:a randomized,open-label,active-controlled trial

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Journal of Integrative Medicine 2017年第3期15卷 201-208页

作者： ghazaleh heydarirad Hossein Rezaeizadeh Rasool Choopani Seyed Hamdollah Mosavat Ahmad Ameri Department of Traditional Medicine School of Traditional Medicine Shahid Beheshti University of Medical Sciences Tehran 15167-45811 Iran Department of Traditional Medicine School of Traditional Medicine Tehran University of Medical Science Tehran 16687-53961 Iran Research Center for Traditional Medicine and History of Medicine Shiraz University of Medical SciencesShiraz 71356-44144 Iran Essence of Parsiyan Wisdom Institute Traditional Medicine and Medicinal Plant Incubator Shiraz University of Medical Sciences Shiraz 71356-44144 Iran Department of Radiation Oncology Imam Hossein Hospital Shahid Beheshti University of Medical SciencesTehran 19946-15611 Iran

BACKGROUND： Xerostomia is one of the most common side effects of radiation therapy among patients with head and neck cancers （HNC）. However, conventional medicine lacks an effective treatment for radiation-induced xerostomia. OBJECTIVE： Synthesizing the traditional use ofAIcea digitata and Malva sylvestris with their known beneficial effects from recent studies, we evaluated the efficacy of the herbs in the quality of life （QOL） of HNC patients with radiation-induced xerostomia. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： This study is a randomized, double-arm, open-label active-controlled clinical trial. We evaluated the effect ofA. digitata and M. sy/vestris on QOL of HNC patients with radiation-induced xerostomia compared with Hypozalix （artificial saliva）. Patients were enrolled from the Imam Hossein Hospital＇s oncology clinic in Shahid Beheshti University of Medica Sciences. Tehran, Iran. MAIN OUTCOME MEASURES： Primary outcome measures in this trial were changes in patients＇ QOL assessed by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Head and Neck Module （EORTC QLQ-H＆N 35）. RESULTS： Between-group analysis showed that the intervention group patients obtained significantly lower （better） total EORTC QLQ-H＆N 35 scores as compared to the control group at the end of the intervention period （P = 0.007）. Mean scores of dry mouth of EORTC QLQ-H＆N 35 was also significantly lower （better） in the intervention group as compared to the control group （P = 0.017）.

关键词： xerostomia medicine Persian traditional hollyhocks common mallow cancer

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Efficacy and safety of Amla(Phyllanthus emblica L.) in non-erosive reflux disease:a double-blind,randomized,placebo-controlled clinical trial

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Journal of Integrative Medicine 2018年第2期16卷 126-131页

作者： Shahnaz Karkon Varnosfaderani Fataneh Hashem-Dabaghian Gholamreza Amin Mahbubeh Bozorgi ghazaleh heydarirad Esmaeil Nazem Mohsen Nasiri Toosi Seyed Hamdollah Mosavat Department of Traditional Medicine School of Traditional MedicineTehran University of Medical Sciences Research Institute for Islamic and Complementary Medicine Iran University of Medical Sciences Department of Traditional Pharmacy Faculty of Traditional MedicineTehran University of Medical Sciences Department of Traditional Medicine School of Traditional MedicineShahid Beheshti University of Medical Sciences Department of Gastroenterology Imam Khomeini Hospital Tehran University of Medical Sciences Research Centre for Traditional Medicine and History of Medicine Shiraz University of Medical Sciences

Background： Gastroesophageal reflux disease （GERD） is one of the most common gastrointestinal com- plaints. GERD, caused by the reflux of stomach contents into the esophagus, leads to troublesome symptoms such as heartburn and regurgitation. It is classified into two types： erosive esophagitis, characterized by visible esophageal mucosa erosion in endoscopy, and non-erosive reflux disease （NERD）. GERD is a chronic and recurrent disease that impairs the quality of life and imposes socioeco- nomic and therapeutic burdens to both patients and society. Objective： Due to the failure of the conventional treatments for GERD and to the traditional use of Amla （Phyllanthus emblica L.）, in addition to beneficial effects shown in recent studies, we evaluated the safety and efficacy of Amla tablet for improvement of symptoms of patients with NERD. Design, setting, participants and interventions： We designed a double-arm, randomized, double-blind, placebo-controlled clinical trial. Sixty-eight patients who had classic symptoms of GERD （heartburn, regurgitation and epigastralgia） for at least three months before the start of the trial were randomized in two parallel groups. Patients in the Amla group received two 500 mg Amla tablets twice a day, after meals, for 4 weeks. In the control group, patients received placebo tablets similar to the Amla prescription. Main outcome measures： The patients were visited at baseline, and at the end of the 2nd and 4th weeks of intervention; their symptoms were measured on a frequency and severity scale for the symptoms of NERD, according to the quality of life in reflux-associated disease questionnaire. Results： Frequencies of heartburn and regurgitation in both groups of the study were significantly reduced after intervention （P 〈 0.001）. Repeated measures logistic regression analysis showed that, in the Amla group, there was a more significant reduction in regurgitation frequency, heartburn frequency, regurgita- tion severity and heartburn se

关键词： Gastroesophageal reflux Non-erosive reflux disease Amla Phyllanthus emblica Phytotherapy Randomized clinical trials

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