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Determinants of neonatal jaundice in Ethiopia:a systematic review and meta-analysis

World Journal of Pediatrics 2022年第11期18卷 725-733页

作者： Habtamu Gebrehana Belay getachew arage debebe Alemu Degu Ayele Bekalu Getnet Kassa Gedefaye Nibret Mihretie Mulugeta Dile Worke Department of Midwifery College of Health SciencesDebre Tabor UniversityP.O.Box 272Debre TaborEthiopia Department of Nursing College of Health SciencesDebre Tabor UniversityDebre TaborEthiopia

Background Neonatal jaundice is a common condition characterized by a yellowish discoloration of the skin,conjunctiva,and sclera caused by elevated serum or plasma bilirubin levels during the newborn *** condition is usually not dangerous,but it can progress to severe hyperbilirubinemia,which can lead to acute bilirubin encephalopathy and kernicterus,a bilirubin-induced neurological ***,this study aimed to assess the pooled prevalence of neonatal jaundice and its determinants in *** Scopus,PubMed,Google Scholar,Embase,and CINAHL databases were searched for studies published between January 1,2010 and July 30,2021.A weighted DerSimonian Laird random-effects model was used to estimate the pooled prevalence of neonatal jaundice and its associated *** I2 was used to calculate the degree of *** funnel plot and Egger's regression test were used to assess publication *** Totally 697 articles were generated from various databases,and the review included a total of eight *** pooled prevalence of neonatal jaundice was 30.96%[95%confidence interval(CI)16.61%–45.31%)]in *** review showed that prolonged labor[adjusted odd ratio(AOR)=3.39;95%CI 2.41–4.77),low birth weight(AOR=5.12;95%CI 3.11–8.72),birth asphyxia(AOR=3.75;95%CI 2.11–6.66),cephalohematoma(AOR=7.07;95%CI 2.72–18.38),ABO incompatibility(AOR=6.05;95%CI 2.95–12.42),Rhesus(RH)incompatibility(AOR=3.77;95%CI 2.04–6.96),male sex(AOR=4.53;95%CI 3.39–6.07),and neonatal sepsis(AOR=2.47;95%CI 1.49–4.08)were identified as a determining factor for neonatal jaundice in *** In low-and middle-income countries,neonatal jaundice is a significant healthcare burden,accounting for a significant portion of global childhood mortality and ***,some low-cost,effective,practical,and dependable solutions have been *** labor,ABO incompatibility,RH incompatibility,birth asphyxia,neonatal sepsis,low birth weight,ceph

关键词： Ethiopia Meta-analysis Neonatal jaundice Systematic review

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