检索结果-南通市图书馆

Effects of castration and testosterone replacement on veno-occlusion during penile erection in the rat

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 1999年第Z1期 53-59页

作者： Vivienne Stopper,Ronald Lewis,Thomas mills Department of Physiology and Endocrinology Medical College of Georgia Augusta GA 30912-3000 USA Department of Surgery Urology Section Department of Surgery Urology Section Department of Physilolgy and Endocrinology Medical College of Georgia Augusta GA 30912-3000 USA

Aim: To determine if androgens directly regulate veno-occlusion or if androgens act indirectly to maintain the penilestructures which control outflow. Methods: Using CASTRATE and TESTO rats, measurement was made of meanarterial pressure (MAP), intracavernosal pressure (CCP), and intracavernosal flow (CCF) during erection resultingfrom stimulation of the autonomic innervation of the penis. CCP and CCF were also measured during saline infusioninto the cavernosal sinuses before and after treatment with sodium nitroprusside (SNP, a nitric oxide donor drag) tofully relax cavernosal smooth muscle. Penile tissue was also collected to measure the content of α actin and proline andhydroxyproline to determine if brief withdrawal of androgenic support led to changes in the number of smooth musclecells or the collagen content of the tissue. Results: Infusion of saline into the cavernosal sinuses demonstrated thatveno-occlusion was defective in CASTRATE rats while reno-occlusion was fully functional in TESTO animal

关键词： castration testosterone cavernous sinus penile erection nitric oxide androgens

Local buckling of thin plate on tensionless elastic foundations under interactive uniaxial compression and shear

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Theoretical & Applied Mechanics Letters 2018年第2期8卷 75-82页

作者： Iianghui Dong Xing Ma Yan Zhuge Julie E.mills School of Natural and Built Environments University of South AustraliaAdelaideSA 5095Australia

This paper uses a mathematical method to develop an analytical solution to the local buckling behaviour of long rectangular plates resting on tensionless elastic Winkler foundations and under combined uniform longitudinal uniaxial compressive and uniform in-plane shear loads. Fitted formulas are derived for plates with clamped edges and simplified supported edges. Two examples are given to demonstrate the application of the current method： one is a plate on tensionless spring foundations and the other is the contact between the steel sheet and elastic solid foundation. Finite element （FE） analysis is also conducted to validate the analytical results. Good agreement is obtained between the current method and FE analysis.

关键词： Buckling coefficient Contact buckling Winkler foundation Interaction curve Finite element analysis

Increased Benthic Algal Primary Production in Response to the Invasive Zebra Mussel (Dreissena polymorpha) in a Productive Ecosystem,Oneida Lake,New York

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2008年第11期50卷 1452-1466页

作者： Rebecca K.Cecala Christine M.Mayer Kimberly L.Schulz Edward L.mills Biology Department Syracuse University Biology Deptartment Department of Environmental Sciences and Lake Erie Center University of Toledo State University of New York School of Environmental Science and Forestry Cornell Biological Field Station and Department of Natural Resources Cornell University

Increased water clarity associated with zebra mussel （Dreissena polymorpha） populations may favor benthic algal primary production in freshwater systems previously dominated by pelagic phytoplankton production. While zebra mussel-mediated water clarity effects on benthic primary production have been implicated in published reports, few production estimates are available. This study estimates benthic primary production in Oneida Lake, NY before and after zebra mussel invasion （1992）, using measured photosynthetic parameters （P^Bmax, α^β and β） from sampled benthic algal communities. In the summers of 2003 and 2004, primary production was measured as O2 evolution from algal communities on hard （cobble） and soft （sediment） substrate from several depths. We also backcast estimates of benthic primary production from measurements of light penetration since 1975. Estimates of whole-lake epipelic and epilithic algal primary production showed a significant （4%） increase and exhibited significantly less interannual variability subsequent to the establishment of zebra mussels. We applied our model to two lakes of differing trophic status; the model significantly overestimated benthic primary production in a hypereutrophic lake, but there was no significant difference between the actual and predicted primary production values in the oligotrophic lake. The hypereutrophic lake had higher zebra mussel densities than Oneida （224 vs. 41 per sample respectively）. Though total community respiration （measured in total darkness） was factored into our model predictions of production, our model may need modification when heterotrophic respiration is a large portion of total community metabolism.

关键词： Dreissena ecosystem engineering nonindigenous species Oneida Lake periphyton primary production.

Solidification and crystallization properties of CaO-SiO_2-Na_2O based mold fluxes

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2009年第3期16卷 261-264页

作者： Sheng-ping He Qian Wang Dan Xie Chu-shao Xu Z.S. Li K.C. mills Chongqing Key Laboratory of Metallurgical Engineering College of Materials Science and Engineering Chongqing University Chongqing 400044 China Department of Materials Imperial College London London SW72AZ UK

Crystallization properties play an important role in keeping a smooth running of continuous casting process and high surface quality of cast strands. To reduce fluorine pollution in slag, a new type of CaO-SiO2-Na2O （CSN） based mold flux was studied. The solidification and crystallization properties, including crystallization temperature, crystallization ratio and solidification mineragraphy, were measured, which were compared with the CaO-SiO2-CaF2 （GF） mold flux. The results show that the crystallization performance is equal to the high fluoride mold powder and CSN can be used for peritectic steel grades sensitive to longitudinal cracking in continuous casting.

关键词： mold fluxes crystallization properties mineragraphy peritectic steel

Geochemical and Nd-Sr Isotopic Compositions of Hypabyssal Adakites in the Torud-Ahmad Abad Magmatic Belt,Northern Central Iran Zone:Analysis of Petrogenesis and Geodynamic Implications

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2021年第6期32卷 1428-1444页

作者： Fazilat Yousefi Ryan D.mills Mahmoud Sadeghian David R.Lentz Christina Wanhainen Habibollah Ghasemi Laicheng Miao Department of Earth Sciences University of New BrunswickFrederictonCanada Department of Geological Sciences University of North Carolina at Chapel HillChapel HillUSA Faculty of Earth Sciences Shahrood University of TechnologyShahroodIran Department of Civil Environmental and Natural Resources EngineeringLulea University of TechnologyLuleaSweden Institute of Geology and Geophysics Chinese Academy of SciencesBeijing100029China

Eocene intermediate to felsic subvolcanic rocks of the Torud-Ahmad Abad magmatic belt(TAMB),in the northern part of the Central Iran zone,are exposed between the Torud and Ahmad Abad regions in South-Southeast *** igneous rocks include hypabyssal dacite,trachyte,andesite,trachy-andesite,and basaltic andesite;they are mainly composed of phenocrysts and microcrystalline groundmass of pyroxene,amphibole,and plagioclase,with minor biotite and titanomagnetite;they form domal structures(plugs and stocks),dikes,and sills that intruded into Neoproterozoic to cogenetic Eocene volcano-sedimentary *** on isotopic analysis of these intermediate to acidic rocks,initial ratios of^(143)Nd/^(144)Nd range from 0.512775 to 0.512893 and initial ratios of^(87)Sr/^(86)Sr range from 0.703746 to 0.705314,with quite positiveε_(Nd(i))values of+3.69 to+*** are enriched in light rare earth elements and large ion lithophile elements and depleted in heavy rare earth elements and high-field strength elements,the SiO_(2) content is(52-62)wt.%,and Na_(2)O content>3 wt.%,Al_(2)O_(3) content>16 wt.%,Yb<1.8 ppm,and Y<18 *** geological,geochemical,and Sr and Nd isotopic data are consistent with adakitic signatures originating by partial melting of the subducted Neo-Tethys oceanic slab(Sabzevar branch)and lithospheric suprasubduction zone *** mantle signatures typifying the rapidly emplaced adakitic rocks(slab(high-silica adakite)and suprasubduction zone(low-silica adakite)melts)together with their locally voluminous extent are evidences that support a locally extensional geodynamic setting;and the evidence is consistent with an evolution to local transpression in the Late Eocene in this convergent margin are environment to rifting(basalts to adakites)towards submarine conditions in the Neogene.

关键词： isotope geochemistry adakite rocks Central Iran zone Shahrood Iran

Micromorphology of Surface Crusts in the Knersvlakte,South Africa

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2009年第2期6卷 189-196页

作者： Sarah-Jane C.Fox Anthony J.mills Rosa M.Poch Department of Soil Science Stellenbosch UniversityStellenbosch South Africa Department of Environment and Soil Science University of LleidaRovira Roure 191 Lleida

Soils in the Knersvlakte are particularly prone to crusting and have lower inherent infiltrability than other soils across western southern Africa. Micromorphological techniques were used to examine the structure and porosity of soil crusts in the Knersvlakte to ascertain why crusting is so intense in this region. Quantile regression using boundary lines was employed to examine the relationships between infiltrability and soil properties for all samples （n = 67）. This analysis showed that infiltrability is potentially maximal at low water- dispersible ＇clay plus silt＇ content and low silt content （r^2 = 0.72 and 0.64; respectively, n = 67）（Figure 2）. The strength of crusts, pH, EC, clay mineralogy, and water-dispersible clay, silt and ＇clay plus silt＇ content were compared, and a pore analysis using optical microscopy was undertaken on images of six soil thin sections （n = 6）（circular and parallel polarizers）. Pore analysis was further undertaken on five horizontal slices of equal dimensions taken through each soil thin section. The porosity samples with low infiltrability （〈 100 mm·hr^-1, n = 4） had greater crust strength, lower porosity （both total and in the least porous slice） and greater water-dispersible ＇day plus silt＇ and silt content than the porosity samples with high infiltrability （〉 100mm·hr^-1, n = 2）. The porosity samples with low infiltrability showed a trend of lower pH and greater water dispersible clay percentage. Porosity varied within the porosity samples due to the presence of dense clay/silt bands （〈 0.5 mm in width） with relatively few air vesicles. The porosity samples with horizontal slices of low porosity （but large numbers of air vesicles） had low infiltrability, while those without slices of low porosity （and relatively few air vesicles） had high infiltrability. We conclude that the intense crusting and resultant low infiltrability of soils in the Knersvlakte appears to be related to the formation of thin, dense clay/silt bands in the

关键词： Infiltrability optical microscopy porosity air vesicles

在线全文

学校读者我要写书评

暂无评论

Breakinq the Silence

英语学习 1999年第8期 4-9页

作者： Ami Chen mills 流水

二十九岁的美籍华裔作家张纯如(Iris Chang)从小生长在美国中西部一个宁静和谐的小镇。她所著的《南京浩劫》(亦译《南京大屠杀》)1.是第一本全面记录「南京大屠杀」的英文书,自九七年底出版以来,迄今已售出五十万本,在西方社会引起很... 详细信息

二十九岁的美籍华裔作家张纯如(Iris Chang)从小生长在美国中西部一个宁静和谐的小镇。她所著的《南京浩劫》(亦译《南京大屠杀》)1.是第一本全面记录「南京大屠杀」的英文书,自九七年底出版以来,迄今已售出五十万本,在西方社会引起很大回响,令西方人士对日本当年侵华罪行有所认知,亦作出抨击。然而,日本当局仍然坚称「南京大屠杀」纯属捏造。日本驻美大使六

关键词： Breakinq the Silence

Resection margin influences the outcome of patients with bilobar colorectal liver metastases

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2016年第34期8卷 1502-1510页

作者： Sara Di Carlo Derek Yeung Jamie mills Abed Zaitoun Iain Cameron Dhanny Gomez Department of General Surgery University of Rome Department of Hepatobiliary Surgery and Pancreatic Surgery Queen’s Medical CentreNottingham University Hospitals NHS Trust Department of Oncology Queen’s Medical CentreNottingham University Hospitals NHS Trust Department of Histo-pathology Queen’s Medical CentreNottingham University Hospitals NHS Trust NIHR Nottingham Digestive Disease Biomedical research Unit University of Nottingham

AIMTo evaluate the outcome of patients with bilobar colorectal liver metastases (CRLM) and identify clinico-pathological variables that influenced survival. METHODSPatients with bilobar CRLM were identified from a prospectively maintained hepatobiliary database during the study period (January 2010-June 2014). Collated data included demographics, primary tumour treatment, surgical data, histopathology analysis and clinical outcome. Down-staging therapy included Oxaliplatin- or Irinotecan- based regimens, and Cetuximab was also used in patients that were K-RAS wild-type. Response to neo-adjuvant therapy was assessed at the multi-disciplinary team meeting and considered for surgery if all macroscopic CRLM were resectable with a clear margin while preserving sufficient liver parenchyma. RESULTSOf the 136 patients included, thirty-two (23.5%) patients were considered inoperable and referred for palliative chemotherapy, and thirty-four (25%) patients underwent liver resection. Seventy (51.4%) patients underwent down-staging therapy, of which 37 (52.8%) patients responded sufficiently to undergo liver resection. Patients that failed to respond to down-staging therapy (n = 33, 47.1%) were referred for palliative therapy. There was a significant difference in overall survival between the three groups (surgery vs down-staging therapy vs inoperable disease, P P P = 0.017). On multi-variate analysis, R0 resection (P = 0.030) and female (P = 0.036) gender significantly influenced overall survival. CONCLUSIONPatients undergoing liver resection with bilobar CRLM have a significantly better survival outcome. R0 resection is associated with improved disease-free and overall survival in this patient group.

关键词： Colorectal liver metastases Chemotherapy Liver resection

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

透析患者的植入型心脏复律除颤器

英国医学杂志中文版 2020年第4期23卷 223-224页

作者： Mark T mills 刘雨(译) Department of Cardiology Sheffield Teaching Hospitals NHS Foundation TrustSheffieldUK 美国纽约西奈山医院肾内科

与一般人群相比,接受透析治疗的终末期肾病患者的年病死率要高出10倍以上。在透析患者中,很大一部分的死亡归因于心源性猝死(SCD)。血液透析患者SCD的年发病率在5%~7%之间,而心力衰竭患者SCD的年发病率为4%,无需透析的慢性肾病患者SCD... 详细信息

与一般人群相比,接受透析治疗的终末期肾病患者的年病死率要高出10倍以上。在透析患者中,很大一部分的死亡归因于心源性猝死(SCD)。血液透析患者SCD的年发病率在5%~7%之间,而心力衰竭患者SCD的年发病率为4%,无需透析的慢性肾病患者SCD的年发病率为1.5%〜2.7%。SCD风险的增加归因于多种促心律失常因素的综合作用,包括透析引起的血流动力学应激和心肌缺血、电解质和体液的位移、左室肥大和纤维化,以及自主神经的调节异常。

关键词：心源性猝死透析患者左室肥大慢性肾病患者透析治疗心力衰竭患者血流动力学自主神经