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Non-Specific Factors Involved in the Treatment： Its Influence on Treatment Adherence

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Journal of Pharmacy and Pharmacology 2017年第6期5卷 340-348页

作者： gerardo A. Fridman Corrientes Pharmacy Santa Fe 1294 City of Corrientes 3400 Argentina

Introduction： The effectiveness of treatment depends on the efficacy of the therapy and the level of compliance of the patient. NF （non-specific factors） involved in treatment are all those effects that do not depend on the pharmacological properties of the drug. Materials and Methods： The job lasted a year. The sample consisted of patients with mental health disorders and was divided into two groups. Treatment compliance was measured with the Morisky-Green Test. Results were compared using the chi square test and relative risk. Results and Discussion： Group A had 23 patients ending 91.3% of them and group B of 22 patients, ending the 77.27%. At the beginning of the study, we found in the group A 0.86 NF/patients while in the group B 0.82 NF/patient. At the end of the study there was a 54.65% decrease in group A while in group B the proportion remained. At the beginning of the study both groups had approximately 40% of compliant patients. Data that remained in the control group rose to 80.95% in group A at the end of the study. Conclusions： The work demonstrates the negative influence of these factors on adherence to treatment.

关键词： Adhesion to treatment nonspecific factors influencing treatment health professional patient family environment.

Resource manipulation reveals flexible allocation rules to growth and reproduction in a Mediterranean evergreen oak

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Journal of Plant Ecology 2014年第1期7卷 77-85页

作者： Fernando Pulido gerardo Moreno Eustolia García José J.Obrador Raúl Bonal Mario Díaz Grupo de Investigación Forestal Ingeniería Forestal y del Medio NaturalUniversidad de ExtremaduraE-10600 PlasenciaCáceresSpain Colegio de Postgraduados Campus TabascoMX-86500 CárdenasTabascoMexico Instituto de Investigación en Recursos Cinegéticos (CSIC-UCLM-JCCM)University of Castilla-La ManchaCiudad RealSpain Department of Biogeography and Global Change(BCG-MNCN) Museo Nacional de Ciencias NaturalesCSICE-28006 MadridSpain

Aims In plants,resource allocation to growth and reproduction may depart from trade-off expectations if(i)investment in growth and reproduction relies on different resource pools,(ii)allocation to reproduction is dependent upon reaching some growth threshold or(iii)reproduction is developmentally linked to growth,both functions relying on the same resource *** examined the effects of enhanced resource level on patterns of resource allocation to growth and reproduction in holm oak(Quercus ilex ***),a Mediterranean evergreen *** In the experimental year(2003),we manipulated the amount of soil nutrients in autumn(to increase nutrient uptake during shoot elongation in the following spring)and soil water in summer(to increase water uptake during acorn growth).Indicators of growth and male and female reproduction were estimated in the preexperimental(2002),experimental(2003)and post-experimental(2004)*** Findings Fertilized trees produced significantly longer shoots,but the number of female flowers per shoot was not affected by *** production of male catkins was also enhanced by *** did not affect the production of female flowers or abortion *** and female reproduction showed no consistent relationship in untreated trees,but resource addition elicited a growth-female reproduction trade-off in the experimental *** sign of this significant relationship changed in the post-experimental year,indicating the existence of lagged effects of resource manipulation on acorn ***,patterns of allocation to growth and reproduction varied as a function of sex,resource availability and year,a result consistent with extreme allocational plasticity in holm oak.

关键词： acorn abortion allocational plasticity dehesa growthreproduction trade-offs nutrient addition Quercus ilex resource allocation

Hot deformation of Mg-Y-Zn alloy with a low content of the LPSO phase studied by in-situ synchrotron radiation diffraction

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Journal of Magnesium and Alloys 2020年第1期8卷 199-209页

作者： Klaudia Horváth Fekete Daria Drozdenko Jan Capek Kristián Máthis Domonkos Tolnai Andreas Stark gerardo Garcés Patrik Dobron Department of Physics of Materials Faculty of Mathematics and PhysicsCharles UniversityKe Karlovu 512116 PragueCzech Republic Nuclear Physics Institute of the CAS 25068ˇRežCzech Republic Magnesium Research Center Kumamoto University2-39-1 Kurokami Chuo-ku860-8555 KumamotoJapan Laboratory for Neutron Scattering and Imaging Paul Scherrer InstituteVilligen PSI5232Switzerland Institute of Materials Science Helmholtz-Zentrum GeesthachtMax-Planck Str.1GeesthachtD21502Germany Department of Physical Metallurgy CENIM-CSICAvenida Gregorio del Amo 8E-28040 MadridSpain

The compressive deformation behavior of the extruded WZ42(Mg98.5Y1Zn0.5 in at.%)magnesium alloy containing a low amount of long-period stacking ordered(LPSO)phase was studied by in-situ synchrotron radiation diffraction *** were conducted at temperatures between room temperature and 350℃.Detailed microstructure investigation was provided by scanning electron microscopy,particularly the backscattered electron imaging and electron backscatter diffraction *** results show that twinning lost its dominance and kinking of the LPSO phase became more pronounced with increasing deformation *** cracks of the LPSO phase and no debonding r at the interface between the LPSO phase and the Mg matrix were observed at temperatures above 200℃.At 350℃,the LPSO phase lost its strengthening effect and the deformation of the alloy was mainly realized by the dynamic recrystallization of the Mg matrix.

关键词： Magnesium alloy LPSO phase Kinking High temperature Synchrotron radiation diffraction

Influence of flooding and vegetation on carbon,nitrogen,and phosphorus dynamics in the pore water of a Spartina alterniflora salt marsh

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Journal of Environmental Sciences 2011年第2期23卷 212-221页

作者： Vanesa L.Negrin Carla V.Spetter Raúl O.Asteasuain gerardo M.E.Perillo Jorge E.Marcovecchio Argentine Institute of Oceanography (IADO CONICETCCT-Bahía Blanca)Camino La Carrindanga km 75Building E-1 CC 804Bahía Blanca 8000Argentina Department of Chemistry Southern National Institute of Chemistry (INQUISUR)Southern National University (UNS)Av Alem 1253Bahía Blanca 8000Argentina Department of Geology Southern National University (UNS)San Juan 670Bahía Blanca 8000Argentina National Technological University Regional Faculty of Bahía Blanca (UTN-FRBB)11 de Abril 461Bahía Blanca 8000Argentina University of the Fraternity of Associations Santo Toms de Aquino (FASTA) Gascón 3145Mar del Plata 7600Argentina

Four sites were selected in a salt marsh in the Bahia Blanca Estuary （Argentina）：（1） low marsh （flooded by the tide twice daily） vegetated by S. alterniflora; （2） non-vegetated low marsh; （3） high marsh （flooded only in spring tides） vegetated by S. alterniflora; （4） non-vegetated high marsh. The pH and Eh were measured in sediments, while dissolved nutrients （ammonium, nitrate, nitrite and phosphate） and particulate organic matter （POM） were determined in pore water, pH （6.2-8.7） was only affected by vegetation in low areas. Eh （from -300 to 250 mV） was lower at low sites than at high ones; in the latter, the values were higher in the non-vegetated sediments. The POM concentration was greater in the high marsh than in the low marsh, with no effect of vegetation. Ammonium was the most abundant nitrogen nutrient species in pore water, except in the non-vegetated high marsh where nitrate concentration was higher. All nitrogen nutrients were affected by both flooding and vegetation. Phosphate was always present in pore water at all sites throughout the year and its concentration varied within narrow limits, with no effect of flooding and greater values always at non-vegetated sites. Our results showed that the variability of the pore water composition within the marsh is greater than the temporal variation, meaning that both tidal flooding and vegetation are important in the dynamics of nutrients and organic matter in the sediment pore water.

关键词： organic matter nutrients flooding Spartina alterniflora

Rayleigh waves from correlation of seismic noise in Great Island of Tierra del Fuego,Argentina:Constraints on upper crustal structure

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Geodesy and Geodynamics 2018年第1期9卷 2-12页

作者： Carolina Buffoni Martin Schimmel Nora Cristina Sabbione María Laura Rosa gerardo Connon Faculty of Astronomical and Geophysical Sciences National University of La PlataPaseo Del Bosque Sin B1900F WAArgentina Institute of Earth SciencesJaume Almera-CSIC Lluis SoléSabarfs S/n Barcelona E-08028Spain Astronomical Station of Rio Grande(EARG) Ruta C y Acceso Aeropuerto9420EARRfo GrandeArgentina National Scientific and Technical Research Council(CONICET) Av.Rivadavia 1917 C1033AAJAutonomous City of Buenos AiresArgentina

In this study, the ambient seismic noise cross-correlation technique is applied to estimate the upper structure of the crust beneath Great Island of Tierra del Fuego（TdF）, Argentina, by the analysis of shortperiod Rayleigh wave group velocities. The island, situated in the southernmost South America, is a key area of investigation among the interaction between the South American and Scotia plates and is considered as a very seismically active one. Through cross-correlating the vertical components of ambient seismic noise registered at four broadband stations in TdF, we were able to extract Rayleigh waves which were used to estimate group velocities in the period band of 2.5-16 s using a timefrequency analysis. Although ambient noise sources are distributed in homogeneously, robust empirical Green＇s functions could be recovered from the cross-correlation of 12 months of ambient noise, The observed group velocities were inverted considering a non-linear iterative damped least-squares inversion procedure and several 1-D shear wave velocity models of the upper crust were *** to the inversion results, the S-wave velocity ranges between 1.75 and 3,7 km/s in the first10 km of crust, depending on the pair of stations considered. These results are in agreement to the major known surface and sub-surface geological and tectonic features known in the area. This study represents the first ambient seismic noise analysis in TdF in order to constraint the upper crust beneath this *** can also be considered as a successful feasibility study for future analyses with a denser station deployment for a more detailed imaging of structure.

关键词： Ambient seismic noise cross-correlation Rayleigh wave dispersion Upper crust Tierra del Fuego

Rethinking the Barcelona clinic liver cancer guidelines:Intermediate stage and Child-Pugh B patients are suitable for surgery?

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World Journal of Gastroenterology 2021年第21期27卷 2784-2794页

作者： Fabrizio Romano Marco Chiarelli Mattia Garancini Mauro Scotti Mauro Zago gerardo Cioffi Matilde De Simone Ugo Cioffi Department of Surgery School of Medicine and SurgeryUniversity of Milano-BicoccaMonza 20900Italy Emergency and Robotic Surgery A.Manzoni HospitalASST LeccoLecco 23900Italy Department of General Surgery San Gerardo HospitalMonza 20900Italy Department of Sciences and Technologies Universitàdegli Studi del Sannio di BeneventoBenevento 82100Italy Department of Surgery University of MilanMilano 20122Italy

According to Barcelona Clinic Liver Cancer recommendations,intermediate stage hepatocellular carcinomas(stage B)are excluded from liver resection and are referred to palliative ***,Child-Pugh B patients are not usually candidates for liver ***,many hepatobiliary centers in the world manage patients with intermediate stage hepatocellular carcinoma or Child-Pugh B cirrhosis with liver resection,maintaining that hepatic resection is not contraindicated in selected patients with non–early-stage hepatocellular carcinoma and without normal liver *** studies demonstrate that resection provides the best survival benefit for selected patients in very early/early and even in intermediate stages of Barcelona Clinic Liver Cancer classification,and this treatment gives good results in the setting of multinodular,large tumors in patients with portal hypertension and/or Child-Pugh B *** this review we explore this controversial topic,and we show through the literature analysis how liver resection may improve the short-and long-term survival rate of carefully selected Barcelona Clinic Liver Cancer B and Child-Pugh B hepatocellular carcinoma ***,other large clinical studies are needed to clarify which patients with intermediate stage hepatocellular carcinoma are most likely to benefit from liver resection.

关键词： Liver surgery Hepatocellular carcinoma Barcelona liver clinic cancer Child B Intermediate stage

Desmoid type fibromatosis: A case report with an unusual etiology

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World Journal of Gastrointestinal Oncology 2017年第9期9卷 385-389页

作者： Syed Faisal Jafri Obada Obaisi gerardo G Vergara Joe Cates Jaswinder Singh Jennifer Feeback Harathi Yandrapu Gastroenterology Research Medical CenterKansas City School of Medicine University of Missouri in Kansas City Pathology Research Medical CenterKansas City General and Vascular Surgery Research Medical CenterKansas City Hematology/Oncology Research Medical CenterKansas City Clinical Research Research Medical CenterKansas City Internal Medicine Department of Research Medical Center and Research Department of Kansas City Veterans Affairs Medical Center

Desmoid type fibromatosis(DTF) is a rare, locally invasive, non-metastasizing soft tissue tumor. We report an interesting case of DTF involving the pancreatic head of a 54-year-old woman. She presented with intermittent dysphagia and significant weight loss within a 3-mo period. Laboratory findings showed mild elevation of transaminases, significant elevation of alkaline phosphatase and direct hyperbilirubinemia, indicating obstructive jaundice. Computerized tomography of the abdomen revealed a mass in the head of the pancreas, dilated common bile duct, and dilated pancreatic duct. Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound showed a large hypoechoic massin the head of the pancreas causing extrahepatic biliary obstruction and pancreatic ductal dilation. The patient underwent a successful partial pancreatico-duodenectomy and cholecystectomy. She received no additional therapy after surgery, and liver function tests were normalized within nine days after surgery. Currently, surgical resection is the recommended first line treatment. The patient will be followed for any recurrence.

关键词： Desmoid type fibromatosis Desmoid tumor Aggressive fibromatosis Pancreas Painless jaundice

Helminth parasites of freshwater fishes from Cuatro Ciénegas,Coahuila,in the Chihuahuan Desert of Mexico:inventory and biogeographical implications

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Integrative Zoology 2014年第3期9卷 328-339页

作者： Rogelio AGUILAR-AGUILAR Andrés MARTÍNEZ-AQUINO Héctor ESPINOSA-PÉREZ gerardo PÉREZ-PONCE DE LEÓN Comparative Biology Department National Autonomous University of MexicoMexico CityMexico Laboratory of Helminthology National Autonomous University of MexicoMexico CityMexico Graduate Program in Biological Sciences National Autonomous University of MexicoMexico CityMexico National Collection of Fish National Autonomous University of MexicoMexico CityMexico

As part of an ongoing inventory of the helminth parasites of freshwater fishes in Mexico, 570 individual fish were collected between Apr 2008 and Oct 2011 in 26 localities along the Cuatro Ciénegas region in Coahuila State, northern Mexico. Seventeen species of hosts, mostly corresponding to Nearctic freshwater elements, were studied. A total of 8324 individual worms were collected during this survey, representing 25 species of helminths, of which 9 were digeneans, 3 monogeneans, 3 acanthocephalans, 9 nematodes and 1 cestode. Most of the records in this checklist represent new host or locality records. The information provided in this checklist may be helpful for our understanding of the biodiversity and historical biogeography of this host-parasite system, because in the Cuatro Ciénegas region occur a Nearctic freshwater fish fauna, along with Neotropical and endemic elements, and from a biogeographical point of view, this may represent a transitional area.

关键词： Acanthocephala Cestoda Cuatro Ciénegas Digenea freshwater fish Mexico Monogenea Nematoda

Diversity, Endemism and Conservation of Ferns(Polypodiales) in the Mexican Mountain Component

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Journal of Mountain Science 2015年第4期12卷 891-904页

作者： SANGINéS-FRANCO Celia LUNA-VEGA Isolda CONTRERAS-MEDINA Raúl ESPINOSA David TEJERO-DíEZ José Daniel RIVAS gerardo Laboratorio de Biogeografía y Sistemática Departamento de Biología Evolutiva Facultad de Ciencias Universidad Nacional Autónoma de México (UNAM) Escuela de Ciencias Universidad Autónoma "Benito Juárez" de Oaxaca (UABJO) Av.Universidad s/n Ex Hacienda de Cinco Se?ores Oaxaca de Juárez CP 68120 Oaxaca México Facultad de Estudios Superiores Zaragoza Unidad Multidisciplinaria de Investigación Experimental ZaragozaUniversidad Nacional Autónoma de México (UNAM) Carrera de Biología Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México MéxicoAvenida de los Barrios Número 1 Colonia Los Reyes Iztacala Tlalnepantla CP 54090 Estado de México México Laboratorio de Biogeografía Acuática Departamento de Biología Comparada Facultad de Ciencias Universidad Nacional Autónoma de México (UNAM)

We analyzed the distributional patterns of95 selected species of leptosporangiate ferns inhabiting the Mexican Mountain Component, using grid-cells of one geographical degree as unit areas,applying endemism indices and richness and beta diversity *** data were obtained from several herbaria and specialized *** grid-cells appear to be important for fern species richness, as they contain 35 to 49 *** gridcells are located in the Sierra Madre Oriental(SMO),Trans-Mexican Volcanic Belt(TMVB) and the Sierra Madre del Sur(SMS).Mean richness by latitudinal belts of one degree showed that the belts with highest values are related to the TMVB and SMS.A total of 13grid-cells were recognized as important from theperspective of endemism; most of them are located also in the SMO, TMVB and *** richest gridcells coincided with one of the main centres of endemism for ferns obtained in this study, located in the convergence of the southern part of the SMO, the eastern portion of the TMVB and the northern part of the SMS, reflecting the high humidity existing on the mountain slopes facing the Gulf of *** important grid-cells recognized from richness and endemism analyses coincide with Mexican Natural Protected *** beta diversity analysis showed a low degree of similarity among grid-cells, implying a high species replacement, as the result of environmental heterogeneity occurring in the Mexican mountain *** the other hand, the spatial analysis suggested a pattern of phytogeographical regionalization comprising twomain areas: the Mexican Transition Zone and the Mexican Central *** play an important role in the Mexican biodiversity and contributing to the beta diversity of Mexico.

关键词： Biogeography Distributional patterns Leptosporangiate ferns Mexico