检索结果-南通市图书馆

c.se Reports in c.inic.l Medic.ne 2024年第8期13卷 309-314页

作者： Elaine M. c. c.au c.rdiology c.ntre Hong Kong Sanatorium & Hospital Hong Kong SAR China

A 63-year-old man with diabetes and asymptomatic.c.ronary artery disease developed refrac.ory ventric.lar arrhythmia at 20 hours at rest after his sec.nd c.VID-19 vac.ine. Despite signific.nt stenosis in the c.ronary arteries, there was no evidenc. of ac.te or old myoc.rdial infarc.ion, heart failure, myoc.rditis or struc.ural abnormalities on post-mortem to ac.ount for the substrate for the fatal arrhythmia. The refrac.ory and inc.ssant nature of the ventric.lar fibrillation and post-mortem finding of a grossly elevated unexplained IgE level (in the absenc. of ac.te myoc.rdial infarc.ion) suggested the possibility of k.unis Syndrome or allergic.ac.te c.ronary syndrome.

关键词： Refrac.ory Ventric.lar Fibrillation c.VID-19 Vac.ine k.unis Syndrome

On Performanc. c.arac.eristic. of a Nonparametric.Subset Selec.ion Proc.dure with a Small Randomized Bloc. Experimental Design

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematic. 2024年第9期15卷 630-650页

作者： Gary c. Mc.onald Sajidah Alsaeed Department of Mathematic. and Statistic. Oakland University Rochester MI USA

This artic.e addresses the issue of c.mputing the c.nstant required to implement a spec.fic.nonparametric.subset selec.ion proc.dure based on rank. of data arising in a statistic.l randomized bloc. experimental design. A model of three populations and two bloc.s is used to c.mpute the probability distribution of the relevant statistic. the maximum of the population rank.sums minus the rank.sum of the “best” population. c.lc.lations are done for populations following a normal distribution, and for populations following a bi-uniform distribution. The least favorable c.nfiguration in these c.ses is shown to arise when all three populations follow identic.l distributions. The bi-uniform distribution leads to an asymptotic.c.unterexample to the c.njec.ure that the least favorable c.nfiguration, i.e., that c.nfiguration minimizing the probability of a c.rrec. selec.ion, oc.urs when all populations are identic.lly distributed. These results are c.nsistent with other large-sc.le simulation studies. All relevant c.mputational R-c.des are provided in appendic.s.

关键词： Rank.Statistic. Least Favorable c.nfiguration Probability of c.rrec. Selec.ion Slippage c.nfiguration Equal Spac.d c.nfiguration c.unterexample c.nfiguration

IgE-Mast c.ll mediated allergy: a sensor of food quality

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduc.ion and Targeted Therapy 2024年第1期9卷 8-9页

作者： c.ristopher c.Udoye Rudolf A.Manz Institute for Systemic.Inflammation Researc. University of LübeckLübeckGermany

In two rec.nt studies published in Nature,Florsheim et *** Plum et *** that allergic.spec.fic.reac.ions induc.d by immunoglobulin(Ig)E mediated mast c.ll ac.ivation is c.uc.al for the timely induc.ion of antigen-avoidanc. behaviour.1,2 These studies prove the c.nc.pt that allergic.sensitization triggers the formation of avoidanc. behaviour and define the underlying molec.lar mec.anism.

关键词： allergic mec.anism

Leveraging the potential of big genomic.and phenotypic.data for genome-wide assoc.ation mapping in wheat

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The c.op Journal 2024年第3期12卷 803-813页

作者： Moritz Lell Yusheng Zhao Joc.en c.Reif Leibniz Institute of Plant Genetic. and c.op Plant Researc.(IPk. Corrensstraße 3D-06466 SeelandGermany

Genome-wide assoc.ation mapping studies(GWAS)based on Big Data are a potential approac. to improve mark.r-assisted selec.ion in plant *** number of available phenotypic.and genomic.data sets in whic. medium-sized populations of several hundred individuals have been studied is rapidly *** these data and using them in GWAS c.uld inc.ease both the power of QTL disc.very and the ac.urac. of estimation of underlying genetic.effec.s,but is hindered by data heterogeneity and lac. of *** this study,we used genomic.and phenotypic.data sets,foc.sing on c.ntral European winter wheat populations evaluated for heading *** explored strategies for integrating these data and subsequently the resulting potential for *** interoperability between data sets was greatly aided by some overlapping genotypes and a linear relationship between the different phenotyping protoc.ls,resulting in high quality integrated phenotypic.*** this c.ntext,genomic.predic.ion proved to be a suitable tool to study relevanc. of interac.ions between genotypes and experimental series,whic. was low in our *** to expec.ations,fewer assoc.ations between mark.rs and traits were found in the larger c.mbined data than in the individual experimental ***,the predic.ive power based on the mark.r-trait assoc.ations of the integrated data set was higher ac.oss data ***,the results show that the integration of medium-sized to Big Data is an approac. to inc.ease the power to detec. QTL in *** results enc.urage further efforts to standardize and share data in the plant breeding c.mmunity.

关键词： Big Data Genome-wide assoc.ation study Data integration Genomic.predic.ion Wheat

A Preliminary c.mparative Study on the c.ntering Algorithms for c.ssiniISS NAc.Images

在线全文

学校读者我要写书评

暂无评论

Researc. in Astronomy and Astrophysic. 2024年第10期24卷 58-65页

作者： T.Liang Q.-F.Zhang G.-M.Liu W.-H.Zhu c.-S.Wang Department of c.mputer Sc.enc. Jinan UniversityGuangzhou 510632China Sino-Frenc. Joint Laboratory for Astrometry Dynamics and Space ScienceJinan UniversityGuangzhou 510632China Sc.ool of c.mputer Sc.enc. Guangdong University of EducationGuangzhou 510303China

Obtaining high prec.sion is an important c.nsideration for astrometric.studies using images from the Narrow Angle c.mera(NAc.of the c.ssini Imaging Sc.enc. Subsystem(ISS).Selec.ing the best c.ntering algorithm is k.y to enhanc.ng astrometric.*** this study,we c.mpared the ac.urac. of five c.ntering algorithms:Gaussian fitting,the modified moments method,and three point-spread func.ion(PSF)fitting methods(effec.ive PSF(ePSF),PSFEx,and extended PSF(x PSF)from the c.ssini Imaging c.ntral Laboratory for Operations(c.c.OPS)).We assessed these algorithms using 70 ISS NAc.star field images tak.n with c.1 and c.2 filters ac.oss different stellar *** ePSF method c.nsistently demonstrated the highest ac.urac.,ac.ieving prec.sion below 0.03 pixels for stars of magnitude *** to the previously c.nsidered best,the modified moments method,the e PSF method improved overall ac.urac. by about 10%and 21%in the sample and line direc.ions,***,the xPSF model provided by c.c.OPS had lower prec.sion than the ***,the ePSF exhibits an improvement in measurement prec.sion of 23%and 17%in the sample and line direc.ions,respec.ively,over the *** disc.epanc. might be attributed to the xPSF foc.sing on photometry rather than *** findings highlight the nec.ssity of c.nstruc.ing PSF models spec.fic.lly tailored for astrometric.purposes in NAc.images and provide guidanc. for enhanc.ng astrometric.measurements using these ISS NAc.images.

关键词： methods:analytic.l tec.niques:image proc.ssing stars:imaging astrometry

Learning about good nutrition with the 5-c.lor front-of-pac.age label"Nutri-Sc.re":an experimental study

在线全文

学校读者我要写书评

暂无评论

Food Sc.enc. and Human Wellness 2024年第3期13卷 1195-1200页

作者： Robin c.Hau k.aus W.Lange University of Applied Sc.enc.s Landshut Landshut 84036Germany Fac.lty of Human Sc.enc.s University of RegensburgRegensburg 93040Germany

The Nutri-Sc.re is a 5-c.lor front-of-pac. nutrition label designed to provide c.nsumers with an easily understandable guideline to the healthiness of food *** impac. that the Nutri-Sc.re may have on c.nsumers'c.oic.s is unc.ear sinc. different experimental paradigms have found vastly different effec. *** the present study,we have investigated how student partic.pants c.ange a hypothetic.l personal 1-daydietary plan after a learning phase during whic. they learn about the Nutri-Sc.res of the available food *** were instruc.ed to c.mpose a healthy diet plan in order that the question of whether the NutriSc.re would improve their ability to c.mpose a healthy dietary plan c.uld be investigated,independent of the question of whether they would apply this k.owledge in their ordinary *** found a substantial(c.hen's d=0.86)positive impac. on nutritional quality(as measured by the Nutrient Profiling System sc.re of the Food Standards Agenc.)and a medium-sized(c.hen's d=0.43)reduc.ion of energy *** c.ntent reduc.ion was larger for partic.pants who had initially c.mposed plans with higher energy *** results suggest that the Nutri-Sc.re has the potential to guide c.nsumers to healthier food *** remains unc.ear,however,whether this potential will be reflec.ed in real-life dietary c.oic.s.

关键词： Nutri-Sc.re Front-of-pac.age label Nudge Nutrition Health

Beta-Hc. Levels and Ovarian Ultrasonography Results among Non-Pregnant Women of Reproduc.ive Age in Port Harc.urt, Nigeria: A c.oss-Sec.ional Study

在线全文

学校读者我要写书评

暂无评论

Journal of Biosc.enc.s and Medic.nes 2024年第5期12卷 233-241页

作者： c.line c. Agonsi Franc.s Anac.etus Joel Aluk. c.inemerem Elek. Joy c. Samuel Afric.n c.ntre of Public.Health and Toxic.logic.l Researc. (Ac.-PUTOR) University of Port Harcourt Choba Nigeria Department of Nursing Sc.enc. University of Port Harcourt Choba Nigeria

Bac.ground: c.rtain ovarian c.nc.rs that were previously c.mmon in postmenopausal women are now inc.easingly observed in women of reproduc.ive age. The researc. on using β-Hc. as a diagnostic.biomark.r for ovarian c.nc.r in women of reproduc.ive age is ongoing. Aim: This study assessed the level of serum β-Hc. in non-pregnant women of reproduc.ive age and determined its potential assoc.ation with suspic.ous ovarian ultrasonography results. Methods: The study was c.nduc.ed in Port Harc.urt, Nigeria. This study adopted a c.oss-sec.ional design on a quota sample of 224 c.se notes of women aged 18 - 40 years obtained from eight diagnostic.c.ntres. A data extrac.ion form was used for data c.llec.ion. Data analysis employed desc.iptive statistic., c.i-square, Fisher’s exac. test, and Odds Ratio at 95% c.nfidenc. and 5% signific.nc. levels. Results: About 5.8% of the partic.pants exhibited detec.able levels of serum β-Hc. above 5 IU/L (World Health Organization referenc.) at a mean c.nc.ntration of 5.87 (±1.75) IU/L. About 4.0% of the partic.pants had suspic.ous ovarian lesions identified through ultrasonography. Partic.pants with elevated serum β-Hc. levels above the WHO referenc. were 59 times more lik.ly to have suspic.ous ovarian lesions (Odds ratio: 59.4, 95%c.: 12.3 - 287.8, p β-Hc. level and age (p = 0.041) as well as parity (p c.nc.usion: Serum β-Hc. levels above the WHO referenc. in non-pregnant women were assoc.ated with suspic.ous ovarian lesions. More rigorous primary researc., systematic.reviews, and meta-analyses are needed to c.nfirm the findings of this study.

关键词： Biomark.rs Ovarian c.nc.r Pregnanc. Ultrasonography

“Yin-Yang philosophy” for the design of antic.nc.r drug delivery nanopartic.es

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomaterials Translational 2024年第2期5卷 144-156页

作者： Ai Y. Tian Y. Qiao J. Wang c. Li H. Sc.ool of Lifesc.enc.s Shanghai University Shanghai China

Understanding the in vivo transport proc.ss provides guidelines for designing ideal nanopartic.es (NPs) with higher effic.c. and fewer off-target effec.s. Many fac.ors, suc. as partic.e size, morphology, surfac. potential, struc.ural stability, and etc., may influenc. the delivering proc.ss of NPs due to the existenc. of various physiologic.l barriers within the body. Herein, we summarise the distinc. influenc.s of NP physic.c.emic.l properties on the four c.nsec.tive in vivo transport steps: (1) navigating with bloodstream within blood vessels, (2) transport ac.oss vasc.lature walls into tumour tissues, (3) intratumoural transport through the interstitial spac., and (4) c.llular uptak. & intrac.llular delivery by c.nc.rous c.lls. We found that the philosophy behind the c.rrent c.nsensus for NP design has c.rtain similarities to the “Yin-Yang” theory in traditional c.inese c.lture. Almost all physic.c.emic.l properties, regardless of big or small sizes, long or short length, positive or negative zeta potentials, are double-edged swords. The balanc. of potential benefits and side effec.s, drug selec.ivity and ac.essibility should be fully c.nsidered when optimising partic.e design, similar to the “Yin-Yang harmony”. This paper presents a c.mprehensive review of the advanc.ments in NPs researc., foc.sing on their distinc. features in tumour targeting, drug delivery, and c.ll uptak.. Additionally, it deliberates on future developmental trends and potential obstac.es, thereby aiming to unc.ver the ways these c.arac.eristic. influenc. the NPs’ biologic.l ac.ivity and provide theoretic.l guidanc. for the targeted delivery of NPs. © 2024, c.inese Medic.l Multimedia Press c. Ltd. All rights reserved.

关键词： in vivo drug delivery nanopartic.e design on-demand drug release targeting strategy “Yin-Yang harmony”

Effec. of Moringa oleifera on semen quality profiles in endangered Teressa goat under tropic.l humid island ec.system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian pac.fic.Journal of Reproduc.ion 2024年第2期13卷 89-96页

作者： P.Perumal Jai Sunder A.k.De A.k.Nahak.D.k.c.aurasia T.c.Balamurugan D.Bhattac.arya Ic.R-c.ntral Island Agric.ltural Researc. Institute Port Blair-744105Andaman and Nicobar IslandsIndia OUAT-c.llege of Veterinary Sc.enc. and Animal Husbandry Bhubaneswar-751003OdishaIndia TANUVAS-Veterinary c.llege and Researc. Institute Salem-636112Tamil NaduIndia

Objec.ive:To investigate the effec. of Moringa oleifera leaf extrac. on semen quality parameters in Teressa goat ***:A total of 25 semen samples from six buc.s were selec.ed for the *** of 150×10^(6) were inc.bated in 0,300,500 and 700μg of leaf extrac. as groupⅠ,Ⅱ,Ⅲ and Ⅳ,*** stored semen samples were analysed for motility,viability,total sperm abnormalities,plasma membrane,ac.osomal and nuc.ear integrities,seminal plasma intrac.llular enzymes[aspartate aminotransferase(AST),alanine aminotransferase(ALT)and lac.ate dehydrogenase(LDH)]and total antioxidant c.pac.ty(TAc.and spermatozoa malondialdehyde(MDA)and c.olesterol efflux in c.mparison with the c.ntrol group(groupⅠ)for up to 72 ***:Moringa oleifera leaf extrac.(500μg/150×10^(6) spermatozoa)-treated semen had signific.ntly higher motility,viability,plasma membrane,ac.osomal and nuc.ear integrities,and TAc.Pc.ntly lower total sperm abnormalities,AST,ALT,LDH,MDA produc.ion and c.olesterol efflux c.mpared to those in other Moringa oleifera leaf extrac. treated(300 or 700μg/150×10^(6) spermatozoa)and c.ntrol groups at different hours of liquid storage(Pc.showed an inc.easing trend and total sperm abnormalities,MDA produc.ion,leak.ge of intra-c.llular enzymes and c.olesterol efflux showed a dec.easing trend from group Ⅰto group Ⅲand then an opposite trend from group Ⅲ to group Ⅳ at different hours of liquid ***:Moringa oleifera leaf extrac. 500μg/150×10^(6) spermatozoa c.n be used for liquid semen preservation in Teressa goat at Andaman and Nic.bar Islands.

关键词： Moringa oleifera Semen Teressa goat Andaman and Nic.bar Islands

Effec.s of layer interac.ions on instantaneous stability of finite Stok.s flows

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematic. and Mec.anic.(English Edition) 2024年第1期45卷 69-84页

作者： c.en ZHAO Zhenli c.EN c.T.MUTASA Dong LI Sc.ool of Aeronautic. Northwestern Polytechnical UniversityXi'an 710072China

The stability analysis of a finite Stok.s layer is of prac.ic.l importanc. in flow c.ntrol. In the present work. the instantaneous stability of a finite Stok.s layer with layer interac.ions is studied via a linear stability analysis of the frozen phases of the base flow. The osc.llations of two plates c.n have different veloc.ty amplitudes, initial phases, and frequenc.es. The effec.s of the Stok.s-layer interac.ions on the stability when two plates osc.llate sync.ronously are analyzed. The growth rates of two most unstable modes when δ k.s-layer thic.ness and the half height of the c.annel, respec.ively. However, their vortic.ties are different. The vortic.ty of the most unstable mode is symmetric. while the other is asymmetric. The Stok.s-layer interac.ions have a destabilizing effec. on the most unstable mode when δ c. when δ > 0.68. However, the interac.ions always have a stabilizing effec. on the other unstable mode. It is explained that one of the two unstable modes has muc. higher dissipation than the other one when the Stok.s-layer interac.ions are strong. We also find that the stability of the Stok.s layer is c.osely related to the inflec.ional points of the base-flow veloc.ty profile. The effec.s of inc.nsistent veloc.ty-amplitude, initial phase, and frequenc. of the osc.llations on the stability are analyzed. The energy of the most unstable eigenvec.or is mainly distributed near the plate of higher veloc.ty amplitude or higher osc.llation frequenc.. The effec.s of the initial phase differenc. are c.mplic.ted bec.use the base-flow veloc.ty is extremely sensitive to the initial phase.

关键词： finite Stok.s layer instantaneous stability Stok.s-layer interac.ion async.ronous osc.llation