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History of the infantile hepatic hemangioma:From imaging to generating a differential diagnosis

World Journal of Clinical Pediatrics 2016年第3期5卷 273-280页

作者： Maria Gnarra gerald behr Alison Kitajewski June K Wu Sudha A Anupindi Carrie J Shawber Nick Zavras Dimitrios Schizas Chris Salakos Konstantinos P Economopoulos Vascular Biology Program Department of SurgeryBoston Children's Hospital and Harvard Medical School Department of Radiology Columbia University Medical Center Department of Surgery Columbia University Medical Center Department of Radiology the Children's Hospital of PhiladelphiaUniversity of Pennsylvania Perelman School of Medicine Department of OB/GYN Columbia University Medical Center Department of Pediatric Surgical "ATTIKO" General University Hospital Society of Junior Doctors Surgery Working Group Department of Surgery Massachusetts General HospitalHarvard Medical School

We aim to provide an up-to-date summary of infantile hepatic hemangioma(IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the *** peer-reviewed articles on hepatic infantile hemangiomas,published between 2000 and 2015,were reviewed for this *** is the most common hepatic vascular tumor in *** a liver mass is identified in an infant,the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma,hepatoblastoma,metastatic neuroblastoma,so careful physical examination,imaging studies,and,if indicated,tumor markers and biopsy,are of pivotal importance to ascertain the correct *** the benign nature of IHHs,some of these lesions may demand medical and/or surgical intervention,especially for multiple and diffuse *** can include hepatomegaly,hypothyroidism and cardiac ***,a close follow-up is required until complete involution of the *** propose an algorithm to guide the physicians towards the proper management of hepatic lesions.

关键词： Hepatic hemangiomas Infant Children Vascular tumors

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