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Hepatobiliary Surgery and Nutrition 2021年第2期10卷 267-269页

作者： georgios K.Glantzounis Anastasia Karampa Dimitra Peristeri HPB Unit Department of SurgeryUniversity Hospital of Ioannina and School of MedicineUniversity of IoanninaIoanninaGreece

Radiological simultaneous portohepatic vein embolization(RASPE)is a relatively new technique,which aims to rapidly increase the future liver remnant(FLR)in patients with very small FLR in order to undergo major hepate... 详细信息

关键词： hepatic hepatectomy simultaneous

Closure of a persistent sphincterotomy-related duodenal perforation by placement of a covered self-expandable metallic biliary stent

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World Journal of Gastroenterology 2011年第40期17卷 4539-4541页

作者： Antonios Vezakis georgios Fragulidis Constantinos Nastos Anneza Yallourou Andreas Polydorou Dionisios Voros 2nd Department of Surgery Endoscopy Unit Aretaieion Hospital University of Athens Athens 11528 Greece

Retroperitoneal duodenal perforation as a result of endoscopic biliary sphincterotomy is a rare complication, but it is associated with a relatively high mortality risk, if left untreated. Recently, several endoscopic techniques have been described to close a variety of perforations. In this case report, we describe the closure of a persistent sphincterotomy-related duodenal perforation by using a covered self-expandable metallic biliary (CEMB) stent. A 61-year-old Greek woman underwent an endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy for suspected choledo-cholithiasis, and a retroperitoneal duodenal perforation (sphincterotomy-related) occurred. Despite initial conservative management, the patient underwent a laparotomy and drainage of the retroperitoneal space. After that, a high volume duodenal fistula developed. Six weeks after the initial ERCP, the patient underwent a repeat endoscopy and placement of a CEMB stent with an indwelling nasobiliary drain. The fistula healed completely and the stent was removed two weeks later. We suggest the transient use of CEMB stents for the closure of sphincterotomy-related duodenal perforations. They can be placed either during the initial ERCP or even later if there is radiographic or clinical evidence that the leakage persists.

关键词： Endoscopic sphincterotomy Complications Retroperitoneal perforation Duodenal perforation Metallic stent

Real-time impact of power balancing on power system operation with large scale integration of wind power

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Journal of Modern Power Systems and Clean Energy 2017年第2期5卷 202-210页

作者： Abdul BASIT Anca D.HANSEN Poul E.SØRENSEN georgios GIANNOPOULOS Department of Wind Energy Technical University of DenmarkFrederiksborgvej 3994000 RoskildeDenmark Sino-Danish Center for Education and Research Niels Jensens Vej 28000 AarhusDenmark ELIA SYSTEM OPERATOR Keizerslaan 201000 BrusselsBelgium

Highly wind power integrated power system requires continuous active power regulation to tackle the power imbalances resulting from the wind power forecast errors. The active power balance is maintained in real-time with the automatic generation control and also from the control room, where regulating power bids are activated manually. In this article, an algorithm is developed to simulate the activation of regulating power bids, as performed in the control room, during power imbalance between generation and load demand. In addition, the active power balance is also controlled through automatic generation control, where coordinated control strategy between combined heat and power plants and wind power plant enhances the secure power system operation. The developed algorithm emulating the control room response,to deal with real-time power imbalance, is applied and investigated on the future Danish power system model. The power system model takes the hour-ahead regulating power plan from power balancing model and the generation and power exchange capacities for the year 2020 into *** real-time impact of power balancing in a highly wind power integrated power system is assessed and discussed by means of simulations for different possible scenarios.

关键词： Wind power plant(WPP) Simulation power Balancing model(SimBa) Centralised or de-centralised combined heat and power plant(CHP or DCHP) Automatic generation control(AGC) Rolling balance

Translational research and innovation in modern transplant practice:Paradigms from Greece and around the world

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World Journal of Transplantation 2023年第2期13卷 25-27页

作者： georgios Tsoulfas Ioannis Boletis Vassilios Papalois Department of Transplantation Surgery Aristotle University School of MedicineThessaloniki 54124Greece Department of Nephrology EKPA UniversityAthens 11527Greece Department of Transplant Surgery Imperial College Renal and Transplant CentreLondon W120HSUnited Kingdom

The continuous clinical and technological advances,together with the social,health and economic challenges that the global population faces,have created an environment where the evolution of the field of transplantation is essentially *** goal of this special issue is to provide a picture of the current status of transplantation in Greece as well as in many other countries in Europe and around the *** from Greece and several other countries provide us with valuable insight into their respective areas of transplant expertise,with a main focus on the field of translational research and *** papers that are part of this Special Issue“Translational Research and Innovation and the current status of Transplantation in Greece”have presented innovative and meaningful approaches in modern transplant research and *** provide us with a clear overview of the current landscape in transplantation,including liver transplantation in the context of a major pandemic,the evolution of living donor kidney transplantation or the evolution of the effect of hepatitis C virus infection in transplantation,while at the same time explore more recent challenges,such as the issue of frailty in the transplant candidate and the changes brought by newer treatments,such as immunotherapy,in transplant ***,they offer us a glimpse of the effect that technological innovations,such as virtual reality,can have on transplantation,both in terms of clinical and educational *** as critical is the fact that this Special Issue emphasizes the multidisciplinary,collaborative efforts currently taking place that link transplant research and innovation with other cutting-edge disciplines such as bioengineering,advanced information technology and artificial *** this Special Issue,in addition to the clinical and research evolution of the field of transplantation,we are witnessing the importance of interdisciplinary collaboration in medicine

关键词： Translational research Non-alcoholic fatty liver disease Immunotherapy Pandemic Liver transplantation Bioengineering Artificial intelligence Immunosuppression Transplant oncology Living donor kidney transplantation

Global dissemination of minimally invasive living donor hepatectomy: What are the barriers?

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 776-787页

作者： Christos Dimitrios Kakos Angelos Papanikolaou Ioannis A Ziogas georgios Tsoulfas Surgery Working Group Society of Junior DoctorsAthens 15123Greece Department of Transplant Surgery Aristotle University of ThessalonikiSchool of MedicineThessaloniki 54622Greece Department of Surgery Johns Hopkins University School of MedicineBaltimoreMD 21287United States Department of Surgery University of Colorado Anschutz Medical CampusAuroraCO 80045United States

Minimally invasive donor hepatectomy(MIDH)is a relatively novel procedure that can potentially increase donor safety and contribute to faster rehabilitation of *** an initial period in which donor safety was not effectively validated,MIDH currently seems to provide improved results,provided that it is conducted by experienced *** selection criteria are crucial to achieve better outcomes in terms of complications,blood loss,operative time,and hospital *** a pure laparoscopic technique,various approaches have been recommended such as hand-assisted,laparoscopic-assisted,and robotic *** latter has shown equal outcomes compared to open and laparoscopic approaches.A steep learning curve seems to exist in MIDH,mainly due to the fragility of the liver parenchyma and the experience needed for adequate control of *** review investigated the challenges and the opportunities of MIDH and the barriers to its global *** need expertise in liver transplantation,hepatobiliary surgery,and minimally invasive techniques to perform *** can be categorized into surgeon-related,institutionalrelated,and *** robust data and the creation of international registries are needed for further evaluation of the technique and the acceptance from more centers worldwide.

关键词： Minimally invasive donor hepatectomy Liver transplantation Living donation Laparoscopic donor hepatectomy Global surgery

Ischemic preconditioning-induced hyperperfusion correlates with hepatoprotection after liver resection

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World Journal of Gastroenterology 2010年第15期16卷 1871-1878页

作者： Oleg Heizmann georgios Meimarakis Andreas Volk Daniel Matz Daniel Oertli Rolf J Schauer Department of Surgery University Hospital Basel Department of Surgery Klinikum of the Ludwig-Maximilians-University-Grosshadern University of Munich Department of Surgery University Hospital of Dresden Department of Surgery Academic Hospital of the Ludwig-Maximilians-University of Munich

AIM:To characterize the impact of the Pringle ma-neuver (PM) and ischemic preconditioning (IP) on total blood supply to the liver following hepatectomies. METHODS: Sixty one consecutive patients who un-derwent hepatic resection under in flow occlusion were randomized either to receive PM alone (n = 31) or IP (10 min of ischemia followed by 10 min of reperfusion) prior to PM (n = 30). Quantification of liver perfusion was measured by Doppler probes at the hepatic artery and portal vein at various time points after reperfusion of remnant livers. RESULTS: Occlusion times of 33 ± 12 min (mean ± SD) and 34 ± 14 min and the extent of resected liver tissue (2.7 segments) were similar in both groups. In controls (PM), on reperfusion of liver remnants for 15 min, portal perfusion markedly decreased by 29% while there was a slight increase of 8% in the arterial blood flow. In contrast, following IP + PM the portal vein flow remained unchanged during reperfusion and a significantly increased arterial blood flow (+56% vs baseline) was observed. In accordance with a better postischemic blood supply of the liver, hepatocellular injury, as measured by alanine aminotransferase (ALT) levels on day 1 was considerably lower in group B compared to group A (247 ± 210 U/I vs 550 ± 650 U/I, P < 0.05). Additionally, ALT levels were significantly correlated to the hepatic artery in ***: IP prevents postischemic flow reduction of the portal vein and simultaneously increases arterial perfusion, suggesting that improved hepatic macrocirculation is a protective mechanism following hepatectomy.

关键词： Ischemic preconditioning Reperfusion injury Liver Surgery Liver blood flow

Choroidal neovascularization post macular surgery:a case series

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International Journal of Ophthalmology(English edition) 2018年第8期11卷 1425-1429页

作者： georgios Tsokolas Benjamin Clarke Hussein Almuhtaseb Bhaskar Gupta Eye Unit University Hospital Southampton

Dear Editor,My name is georgios Tsokolas and I am currently working as Medical Retina Research Fellow at the Eye Unit of Southampton General Hospital in United Kingdom.

关键词： Choroidal neovascularization post macular surgery a case series

Volumetric assessment of hepatic grafts using a light detection and ranging system for 3D scanning:Preliminary data

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World Journal of Hepatology 2022年第7期14卷 1504-1511页

作者： georgios Katsanos Konstantina-Eleni Karakasi Ion-Anastasios Karolos Athanasios Kofinas Nikolaos Antoniadis Vassilios Tsioukas georgios Tsoulfas Department of Transplantation Medical SchoolAristotle University of ThessalonikiHippokration General HospitalThessaloniki 54642Greece Department of Rural and Surveying Engineering Aristotle University of ThessalonikiThessaloniki 54642Greece

BACKGROUND Liver transplantation has evolved into a safe life-saving operation and remains the golden standard in the treatment of end stage liver *** main limiting factor in the application of liver transplantation is graft *** strategies have been developed in order to alleviate graft shortage,such as living donor partial liver transplantation and split liver transplantation for adult and pediatric *** these strategies,liver volume assessment is of paramount importance,as size mismatch can have severe consequences in the success of liver *** To evaluate the safety,feasibility,and accuracy of light detection and ranging(LIDAR)3D photography in the prediction of whole liver graft volume and *** Seven liver grafts procured for orthotopic liver transplantation from brain deceased donors were prospectively measured with an LIDAR handheld camera and their mass was calculated and compared to their actual *** The mean error of all measurements was 17.03 g(range 3.56-59.33 g).Statistical analysis of the data yielded a Pearson correlation coefficient index of 0.9968,indicating a strong correlation between the values and a Student’s t-test P value of *** accuracy of the measurements was calculated at 97.88%.CONCLUSION Our preliminary data indicate that LIDAR scanning of liver grafts is a safe,cost-effective,and feasible method of ex vivo determination of whole liver volume and *** data are needed to determine the precision and accuracy of this method.

关键词： Light detection and ranging Graft volume 3dscan Ex vivo volumetry Liver grafts

A pricing scheme for electric utility’s participation in day-ahead and real-time flexibility energy markets

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现代电力系统与清洁能源学报（英文） 2019年第5期7卷 1294-1306页

作者： Ioannis MAMOUNAKIS Nikolaos EFTHYMIOPOULOS Dimitrios J.VERGADOS georgios TSAOUSOGLOU Prodromos MAKRIS Emmanouel Manos VARVARIGOS Department of Electrical and Computer Engineering Institute of Communication and Computer SystemsNational Technical University of AthensAthensGreece Department of Computer Engineering and Informatics University of PatrasRio-PatrasGreece Department of Electrical and Computer Systems Engineering Monash UniversityMelbourneAustralia

Liberalized electricity markets,smart grids and high penetration of renewable energy sources(RESs)led to the development of novel markets,whose objective is the harmonization between production and demand,usually noted as real time of flexibility *** necessitates the development of novel pricing schemes able to allow energy service providers(ESPs)to maximize their aggregated profits from the traditional markets(trading between wholesale/day-ahead and retail markets)and the innovative flexibility *** the same time,ESPs have to offer their end users(consumers)competitive(low cost)energy *** this context,novel pricing schemes must act,among others,as automated demand side management(DSM)techniques that are able to trigger the desired behavioral changes according to the flexibility market prices in energy consumption curves(ECCs)of the *** pricing schemes proposed so far,*** pricing,interact in an efficient way with wholesale *** they do not provide consumers with strong enough financial incentives to modify their energy consumption habits towards energy cost ***,they do not interact efficiently with flexibility ***,we develop a flexibility real-time pricing(FRTP)scheme,which offers a dynamically adjustable level of financial incentives to participating users by fairly rewarding the ones that make desirable behavioral changes in their *** evaluation results demonstrate that the proposed FRTP is able to offer a 15%–30%more attractive trade-off between the stacked profits of ESPs,*** sum of the profits from retail and flexibility markets,and the satisfaction of consumers.

关键词： Demand response Flexibility markets Realtime pricing(RTP) Behavioral change Energy efficiency

Colonoscopy attachments for the detection of precancerous lesions during colonoscopy:A review of the literature

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World Journal of Gastroenterology 2018年第37期24卷 4243-4253页

作者： Paraskevas Gkolfakis georgios Tziatzios Eleftherios Spartalis Ioannis S Papanikolaou Konstantinos Triantafyllou Hepatogastroenterology Unit Second Department of Internal Medicine-PropaedeuticResearch Institute and Diabetes CenterMedical SchoolNational and Kapodistrian University of Athens''Attikon”University General HospitalAthens 12462Greece Laboratory of Experimental Surgery and Surgical Research National and Kapodistrian University of AthensAthens 12462Greece

Although colonoscopy has been proven effective in reducing the incidence of colorectal cancer through the detection and removal of precancerous lesions, it remains an imperfect examination, as it can fail in detecting up to almost one fourth of existing adenomas. Among reasons accounting for such failures, is the inability to meticulously visualize the colonic mucosa located either proximal to haustral folds or anatomic curves, including the hepatic and splenic flexures. In order to overcome these limitations, various colonoscope attachments aiming to improve mucosal visualization have been developed. All of them-transparent cap, Endocuff, Endocuff Vision and Endorings-are simply mounted onto the distal tip of the scope. In this review article, we introduce the rationale of their development, present their mode of action and discuss in detail the effect of their implementation in the detection of lesions during colonoscopy.

关键词： Adenoma detection rate Adenoma miss rate Colonoscopy Cup Endocuff Endocuff Vision Endorings